The invention discloses a method for manufacturing an MOS
transistor with a
germanium silicon source and drain. The method comprises steps that S1, a
silicon substrate is provided, a gate structure isformed on a surface of the
silicon substrate, and a side wall is formed on a side surface of the gate structure; and S2, a groove having the meandering shape is formed on two sides of the gate structure, including sub steps of S21, a
hard mask layer is formed; S22, a formation region of the groove of the
photolithography process is employed; S23, first
dry etching is performed to form a first portion of the groove; S24, second cleaning process is performed, the cleaning solution adopts the combination of DHF and DIO3, the DHF is employed to remove
contamination on the surface of the silicon substrate, the DIO3 is employed to control the
etching rate of the
oxide layer brought by the DHF, and S25, third wet
etching is performed to form a final groove. The method is advantaged in that control of the cleaning process after the groove is dry can be realized, and loss of an
oxide layer can be reduced or avoided while the
contamination on the surface of the silicon substrate can be sufficiently removed.