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95 results about "Saccharolipid" patented technology
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Saccharolipids describe compounds in which fatty acids are linked directly to a sugar backbone, forming structures that are compatible with membrane bilayers. In the saccharolipids, a monosaccharide substitutes for the glycerol backbone present in glycerolipids and glycerophospholipids. The most familiar saccharolipids are the acylated glucosamine precursors of the lipid A component of the lipopolysaccharides in Gram-negative bacteria. Typical lipid A molecules are disaccharides of glucosamine, which are derivatized with as many as seven fatty-acyl chains. The minimal lipopolysaccharide required for growth in E. coli is Kdo2-Lipid A, a hexa-acylated disaccharide of glucosamine that is glycosylated with two 3-deoxy-D-manno-octulosonic acid (Kdo) residues.
Combined production method for abalone polysaccharide, lipid and protein peptide
The invention discloses a combined production method for abalone polysaccharide, lipid and protein peptide. According to the technological process, the abalone polysaccharide, lipid and protein peptide are prepared by carrying out composite enzymatic hydrolysis, membrane separation, alcohol precipitation, centrifugal separation, freezing crystallization, decoloration, drying and the like on abalone viscera which is taken as a raw material. The combined production method is simple in process, the deficiency that raw materials are utilized insufficiently in a traditional technology can be improved, the emission of wastes in the preparation process can be reduced, and the production cost can be lowered. The abalone polysaccharide and lipid extracted can be taken as intermediate raw materials to research and develop all novel functional foods; and the abalone protein peptide prepared is colorless and tasteless, and the molecular weight is mainly concentrated near 350 dalton, so that the abalone protein peptide is easily absorbed by a human body, and can be widely applied to industries of health-care food, biomedicines, cosmetics and the like relating to human health.
Owner:XIAMEN DAOZHIYUAN BIOTECH
Novel fucosyltransferases and their applications
The present invention relates to nucleic acid and amino acid sequences from Escherichia coli serogroup O126, coding for / representing a novel alpha-1,2-fucosyltransferase. The invention also provides uses and methods for using the alpha-1,2-fucosyltransferase to generate fucosylated products, such as oligosaccharides, (glyco)proteins, or (glyco)lipids, in particular oligosaccharides found in human milk, such as 2′-fucosyllactose.
Owner:CHR HANSEN HMO GMBH
Intra-intestinal nutrient emulsion for tumor patients
InactiveCN103609933ANutritional balanceRecovery functionMetabolism disorderEmulsion deliveryNutritionTryptophan
Owner:湖北一半天制药有限公司
Polygonatum kingianum polysaccharide extract with sugar and lipid metabolism regulating activity and preparation method thereof
InactiveCN104479035AAvoid color changesOrganic active ingredientsMetabolism disorderAmylaseFreeze-drying
The invention discloses an extraction method and application of polygonatum kingianum polysaccharide. The extraction method comprises the following steps: cleaning and slicing polygonatum kingianum taken as a raw material, naturally drying in the sun, and then grinding into coarse powder; extracting with distilled water for three times, then concentrating to a certain concentration, and depositing by using anhydrous ethanol to obtain a polygonatum kingianum polysaccharide crude product; dissolving by using distilled water, adding alpha-amylase to remove starch, depositing by using anhydrous ethanol, and then washing by using anhydrous ethanol, acetone and ethyl ether to remove fat-soluble components to obtain yellow powder; removing protein by using a Sevage method after deionized water dissolution, volatilizing an organic solvent, then performing dialysis, and finally freeze-drying to obtain white powder namely polygonatum kingianum polysaccharide. The obtained polygonatum kingianum polysaccharide is used for preparing tablets and has effects of reducing blood pressure, blood fat and blood sugar.
Owner:YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
Low-toxicity sophorolipid-containing composition and use therefor
ActiveUS20160324747A1Low cytotoxicityLess irritatingAntibacterial agentsCosmetic preparationsLactonic sophorolipidHydroxy group
The present invention provides a low-toxicity sophorolipid-containing composition. The low-toxicity sophorolipid-containing composition contains at least a coloring component, an acidic sophorolipid, a fatty acid, and a hydroxy fatty acid that are derived from an SL-producing yeast culture. The composition contains the following components in the following proportions, in terms of dry weight, based on the total amount of the acidic sophorolipid, a lactonic sophorolipid, the fatty acid, and the hydroxy fatty acid in the composition taken as 100 mass %:(1) acidic sophorolipid: 94 to 99.99 mass %,(2) lactonic sophorolipid: 0 to 2 mass %,(3) total amount of fatty acid and hydroxy fatty acid: 0.01 to 4 mass %
Owner:SARAYA CO LTD
Cationic nano emulsion with anti-allergic effect and preparation method of cationic nano emulsion
ActiveCN104784074ANo toxicityImprove permeabilityCosmetic preparationsAntipyreticSkin sensitizationGlycerol
The invention relates to cationic nano emulsion with an anti-allergic effect. The cationic nano emulsion is characterized by comprising the following components in percentage by mass: 10-30% of a plant anti-allergic compound, 3-30% of glycerin, 5-30% of caprylic / capric triglyceride, 0.1-3% of cholesterol, 2-25% of glycolipid, 0.1-2% of polyquaternary ammonium salt-51, 0.05-0.3% of methylparaben and the balance of water, wherein the plant anti-allergic compound comprises the following components in percentage by mass: 15-30% of olive leaf extract, 5-10% of gorgonian extract, 10-20% of laminaria saccharina extract, 3-5% of piper methysticum extract and the balance of octyldodecanol; the average particle size of nanoparticles is 100-600 nm. The cationic nano emulsion has the benefit of capability of comprehensively and efficiently resisting a skin allergy symptom, is nontoxic to skin, penetrates the skin easily and can quickly achieve the anti-allergic effect.
Owner:PROYA COSMETICS
Application of galactooligosaccharides and derivatives of galactooligosaccharides as SGLT inhibitor
PendingCN110812364AInhibition of transport functionReduce resistanceOrganic active ingredientsMetabolism disorderGalactooligosaccharideOligosaccharide
The invention belongs to the field of marine medicine, and particularly relates to an application of oligosaccharides containing D-galactose and L-galactose and derivatives of the oligosaccharides asa sodium-glucose cotransporter (SGLT) inhibitor. The galactooligosaccharides and derivatives are prepared by the following steps: by using red algae polysaccharide containing the D- / L-galactose as a raw material, performing degradation by using a physical method, a chemical method, a bioenzyme method or any combination of the above methods to prepare the galactooligosaccharides and the derivativesof the galactooligosaccharides with different degrees of polymerization, wherein the molecular skeleton contains the D-galactose and the L-galactose and derivatives thereof. The raw material of the product provided by the invention is from the red algae polysaccharide, and has the advantages of rich resources, a simple preparation process, high safety, clear targets and easy industrialization, the oligosaccharides and the derivatives are used as the SGLT1 and 2 inhibitor, and has broad application prospects in the development of medicines for treating diseases such as diabetes mellitus, obesity, diabetic nephropathy and glucose and lipid metabolism disorder and functional foods for improving non-alcoholic fatty liver diseases.
Owner:OCEAN UNIV OF CHINA
Corydalis edulis extract, pharmaceutical composition containing same and uses thereof
ActiveCN105560390ALower levelLower plasma cholesterolMetabolism disorderDigestive systemDiseaseAlkaloid
The invention provides Corydalis edulis extract, prepared by a method comprising the following steps: (1), after crushing a Corydalis edulis plant, and extracting with alkaline ethyl alcohol or methyl alcohol to obtain an extract; (2), subjecting the extract obtained in step (1) to normal pressure or vacuum concentration to obtain concrete, or spray drying to obtain powder; (3), adding an acid solution into the concrete or powder obtained in step (2), filtering to obtain an acid aqueous solution, adding an alkaline solution to the acid aqueous solution to obtain an alkali treated solution; (4), adding an organic solvent to the alkali treated solution obtained in step (3), vacuum recycling the organic solvent after extracting to obtain Corydalis edulis total alkaloids crude extract. The Corydalis edulis extract or a pharmaceutical composition containing the extract can be used to prepare pharmaceuticals for preventing and / or treating diseases caused by glucose and lipid metabolism disorder.
Owner:BEIJING UNIV OF CHINESE MEDICINE
Method for producing sophorose ester through fermenting waste molasses and waste glycerin
InactiveCN102329833ASolve the problem of difficult storage and large emission pollutionReduce manufacturing costFungiMicroorganism based processesBiotechnologySporeling
The invention relates to a method for producing sophorose ester through fermenting waste molasses and waste glycerin, which comprises the following implementation steps that: (1) spore suspension preparation: torulopsis utilis TJZKBA 10326 is inoculated on the inclined surface of a culture medium and is cultured for 2 to 4 days at the constant temperature being 30 DEG C, and normal saline with the mass concentration being 0.75 percent is added for washing mycelia, and the bacterial suspension is obtained; (2) the bacterial suspension is used for being inoculated into the sterilized liquid seed culture medium, the spore suspension is inoculated into the cooled liquid seed culture medium according to the inoculation quantity with the volume percentage being 2 to 5, and liquid seeds are obtained; (3) the liquid seed culture medium is used for being inoculated into a sterilized 5L fermentation tank, then, the liquid culture medium is inoculated into the cooled fermentation tank culture medium according to the inoculation quantity with the volume percentage being 2 to 5, the fermentation temperature is 30 to 34 DEG C, the dissolved oxygen is controlled to be 30 to 40 percent, and the fermentation time is 48 to 72h; and (4) after the fermentation is completed, the mixed organic solvent of organic solvent ethyl acetate / isopropanol with the same volume as the fermentation liquid is used for extracting the sophorose ester. The method has the advantages that the process is simple, the cost is low, and the effect is obvious.
Owner:天津实发中科百奥工业生物技术有限公司
Method for producing sophorolipid by double carbon source fermentation of waste molasses and illegal cooking oil
ActiveCN103589759AReduce manufacturing costRealize resource utilizationMicroorganism based processesFermentationBiotechnologyEthyl acetate
The invention discloses a method for producing sophorolipid by double carbon source fermentation of waste molasses and illegal cooking oil. The method is characterized by comprising the following steps: (1) inoculating torulopsis utilis to a YPD (yeast peptone dextrose) slant culture medium to prepare a bacterial suspension; (2) preparing a seed solution; (3) inoculating the seed solution to a fermentation medium taking the waste molasses and the illegal cooking oil as substrates for fermenting; (4) extracting the sophorolipid by ethyl acetate. According to the method, wastes are recycled, the production cost of the sophorolipid is greatly reduced, the problems of high emission pollution and large harm in the field of foods for the illegal cooking oil are solved, illegal cooking oil resources are reasonably utilized, complex equipment is not required, a fermentation process is simple and easy to implement, and the development, application and popularization of the sophorolipid are facilitated.
Owner:QINGDAO UNIV OF SCI & TECH
Three-high reducing assisting composition and preparation method thereof
InactiveCN108112973AImprove immunityNo dependenciesYeast food ingredientsNatural extract food ingredientsGINSENG EXTRACTPrunus
The invention relates to the field of healthcare foods. A three-high reducing assisting composition mainly comprises sea cucumber polypeptide, corn oligopeptide, extract of semen cassia, hawthorn extract, ginseng extract, dioscorease rhizome extract, extracts from pueraria, dendrobium extract, indian buead extract, prunus persica kernel extract, L-arabinose, xylooligosaccharide, dietary fiber, arabian jasmine flower, xylitol and nutritive yeast powder. According to the three-high reducing assisting composition, traditional Chinese medicine and high technology are combined; comprehensive conditioning and accurate targeted treatment are combined; the function test result shows that three high can be comprehensively conditioned by assisting, and the effects of integrally regulating sugar andfat and conditioning the three highs together can be achieved; and meanwhile, the intestinal functions can be improved, the body immunity can be improved, and as a result, the effect of treating bothsymptoms and root causes can be achieved; the formula is subjected to scientific mixing of oligopeptide and medical food materials, so that the effects of efficient utilizing, fast acting and assisting of three highs (blood sugar, blood pressure and blood fat) reducing are obviously achieved; in addition, hormone and drug independence are avoided, so that the safety of eating is ensured.
Owner:DALIAN SHENLAN PEPTIDE TECH R & D CO LTD
Benzothiazole derivative, preparation method and application thereof
ActiveCN103044414APromote growthLower systolic blood pressureOrganic chemistryMetabolism disorderChemistryDiabetes model
The invention relates to a benzothiazole derivative, a preparation method and an application thereof, wherein the benzothiazole derivative is 2-m-aniline benzothiazole-1H-pyrazole-3-formamide, and the structural formula of the benzothiazole derivative is shown in the description. The benzothiazole derivative disclosed by the invention can accelerate the growth of saccharomycetes, strengthen the metabolic activity of the saccharomycetes, obviously reduce the plasma triglyceride, the total cholesterol and the high-density lipoprotein of C57 BL / 6J mice fed with high-fat feedstuff, reduce the systolic pressure and the diastolic pressure of model mice, reduce the fasting blood glucose of the model mice, improve the sugar tolerance of the mice, affect the expression of SIRT1 and relevant genes (FOXO1, P53, PPAB gamma and PGC-1 alpha), and obviously improve the sugar and fat metabolism of diabetic model mice. Therefore, the benzothiazole derivative can be applied to preparing medicines for preventing and treating diabetes mellitus and complications of the diabetes mellitus.
Owner:斯芬克司药物研发(天津)股份有限公司
Biological enzyme composite blocking remover and preparation method thereof
ActiveCN112778991AReduce surface and interfacial tensionAvoid adsorptionDrilling compositionAmylaseActive agent
The invention relates to a biological enzyme composite blocking remover and a preparation method thereof, which belong to the technical field of oil field yield increase renovation. The blocking remover comprises the following components by mass: 0.1-0.5% of biological enzyme, 3-5% of a biological surfactant, 5-10% of a biological enzyme stabilizer, and the balance of water; the biological enzyme comprises at least one of xylanase, lipase, cellulase, mannase, protein complex enzyme, amylase and xanthan gum lyase; the biological surfactant is prepared from at least one of the following components: the biological surfactant is mainly prepared from rhamnolipid, sophorolipid and N-acetylgalactosamine; and the biological enzyme stabilizer comprises at least one of the following components: disodium ethylene diamine tetraacetate, citric acid and triethanolamine. The biological enzyme composite blocking remover provided by the invention can solve the problems of permeability reduction and the like caused by low-permeability and medium-low-permeability reservoir reconstruction residual gum and organic matter (wax, asphaltene and the like) blocking in the later development period.
Owner:BC P INC CHINA NAT PETROLEUM CORP +2
Functional edible oil as well as preparation method and application thereof
PendingCN112772731AImprove glucose and lipid metabolism disordersGood for healthEdible oils/fatsFatty acid esterificationNutritionCarbon chain
The invention relates to functional edible oil as well as a preparation method and application thereof. The functional edible oil is formed by performing ternary ester exchange on medium- carbon-chain glyceride, linoleic acid grease and linolenic acid grease. On the basis of the mass of fatty acid, the mass ratio of medium-carbon-chain fatty acid in the medium-carbon-chain glyceride to long-carbon-chain fatty acid in the linoleic acid grease and the linolenic acid grease is 2.3-4.0, and the mass ratio of linoleic acid to linolenic acid in the long-carbon-chain fatty acid is 0.5-1.0. The addition amount of the functional edible oil in foods is greater than or equal to 18.00%. The functional edible oil can significantly improve in-vivo glucose and lipid metabolism disorder, balance and supplement in-vivo necessary and functional fatty acids, and rapidly supplement energy, has a freezing point lower than 7.5 DEG C, can meet consumers, particularly, dietary and nutritional requirements of patients with metabolic syndromes such as overweight, obesity, fatty liver, hyperlipidemia, hyperglycemia, hypertension, hyperblood viscosity, hyperuricemia and hyperinsulinemia and athletes can be met, and the functional edible oil can be widely applied to foods and special medical application industries.
Owner:NANCHANG UNIV
Biological wetting reversal agent for high-temperature high-salt heavy oil reservoir, and preparation method thereof
ActiveCN110669490AIncrease adsorption densityImprove competitive adsorption capacityMicroorganism based processesDrilling compositionActive agentAlkyl polyglycoside
The invention relates to a biological wetting reversal agent, and concretely relates to a biological wetting reversal agent for a high-temperature high-salt heavy oil reservoir, and a preparation method thereof. The reversal agent comprises 20-30 wt% of a rhamnolipid fermentation liquor, 15-20 wt% of a sophorolipid fermentation liquor, 3-5 wt% of alkyl polyglycoside, 0.1-0.3 wt% of an alcohol assistant, and the balance of water. The rhamnolipid fermentation liquor is a Pseudomonas aeruginosa fermentation liquor with the concentration of above 35 g / L; the sophorolipid fermentation liquor is a yeast fermentation liquor with the concentration of above 100 g / L; the alkyl polyglycoside is a biological anionic and nonionic surfactant, and the relative molecular weight is 290-370; and the alcoholassistant is one of butanol, pentanol and hexanol. The biological wetting reversal agent has the advantages of wide oil reservoir application range, simple construction process and good field test effect, has a validity period of above 24 months, and allows the daily oil increase of a single well to be more than 10 t and the input-output ratio to be larger than 1:10.
Owner:CHINA PETROLEUM & CHEM CORP +1
Aquatic product preserving method and preparation method of polysaccharide-lipid edible film solution used by aquatic product preserving method
InactiveCN104055191AHigh viscosityHigh tensile strengthLipidic food ingredientsMeat/fish preservation using chemicalsWater bathsAdditive ingredient
The invention discloses a preparation method of a polysaccharide-lipid edible film solution. The preparation method comprises the following steps: 1, adding starch and a polysaccharide reinforcing agent into distilled water, and stirring; 2, adding a lipid ingredient, lauric acid monoglyceride and glycerinum into the obtained starch suspension, and stirring; 3, adding calcium chloride and a synergist into the obtained polysaccharide-lipid emulsified liquid, homogenizing for 3-6 min at a pressure of 1000-2000 bar to obtain a homogenate; 4, processing the homogenate in a water bath at temperature of 60-85 DEG C for 20-40 min, then cooling to room temperature, and degassing in a vacuum degree of 0.09 MPa for 3-5 min to obtain a homogeneous polysaccharide-lipid edible film solution. Meanwhile, the invention further provides an aquatic product preservation method used by the polysaccharide-lipid edible film solution prepared by using the preparation method. By adopting the polysaccharide-lipid edible film solution provided by the invention, the guarantee period of an aquatic product can be effectively prolonged.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES
Biological polysaccharide gel for oil displacement as well as preparation method and application thereof
The invention belongs to the technical field of tertiary oil recovery and particularly relates to biological polysaccharide gel for oil displacement as well as a preparation method and application thereof. The biological polysaccharide gel comprises the following components in percentage by weight: 2 to 5 percent of biological polysaccharide, 0.1 to 0.5 percent of biological polysaccharide dispersant, 10 to 20 percent of biological polysaccharide gelatinizing agent, 0.5 to 2 percent of biological polysaccharide regulator and the balance of water, wherein the biological polysaccharide is one ofxanthan gum, Curdlan, Welan gum and sclemglucan; the biological polysaccharide dispersant is one of sophorolipid, rhamnolipid, lipopeptid and lipoprotein; and the biological polysaccharide regulatoris one of ferric sulfate, ammonium carbonate, sodium acetate and sodium hydrogen carbonate. The biological polysaccharide gel has high anti-shearing property, temperature resistance and salt resistance and has good application prospect particularly in an oil well of a high-temperature and high-salt oil reservoir; and in field application, the water content is reduced by over 10 percent, the validity period exceeds 60 days and the average daily-increased oil quantity is more than 5 t.
Owner:CHINA PETROLEUM & CHEM CORP +1
Fucosyltransferases and their applications
The present invention relates to nucleic acid and amino acid sequences from Escherichia coli serogroup O126, coding for / representing a novel alpha-1,2-fucosyltransferase. The invention also provides uses and methods for using the alpha-1,2-fucosyltransferase to generate fucosylated products, such as oligosaccharides, (glyco)proteins, or (glyco)lipids, in particular oligosaccharides found in human milk, such as 2′-fucosyllactose.
Owner:CHR HANSEN HMO GMBH
Sophorolipid compound for improving soil and spraying device
ActiveCN114130560ASolve the stickinessReduce volumeContaminated soil reclamationLiquid spraying apparatusSoil scienceSoil remediation
The invention discloses a sophorolipid compound for improving soil and a spraying device, and belongs to the field of soil remediation. The invention relates to a sophorolipid compound for improving soil. The sophorolipid compound is prepared from the following components: sophorolipid, NaCl, ethylenediamine tetraacetic acid, diethyl aminoethyl hexanoate, konjac glucomannan and water. The spraying device for improving the soil comprises a storage layer, a rotating layer and a base which are sequentially connected from top to bottom, a plurality of helical teeth are arranged at the joint of the storage layer and the rotating layer, outflow channels are arranged above the adjacent helical teeth, and the outflow channels are communicated with the storage layer. According to the technical scheme, due to the special sprayed substance, the sprayed substance is a sophorolipid compound with certain viscosity. Therefore, in the technical scheme, the sophorolipid compound flowing from the storage layer to the outflow channel is cut through the helical teeth, so that the agglomerated viscous compound is prevented from blocking the channel, the volume of the compound is reduced, the single-flow sophorolipid compound can be sprayed out conveniently, and the spraying speed and distance of the sophorolipid compound can be kept conveniently.
Owner:HEFEI UNIV OF TECH
Special grease base oil for functional food as well as preparation method and application of special grease base oil
PendingCN112772924AWide melting rangeImprove glucose and lipid metabolism disordersEdible oils/fats with fatty acid estersFood ingredient functionsBiotechnologyNutrition
The invention discloses special grease base oil for a functional food as well as a preparation method and application of the special grease base oil. The special grease base oil is formed by performing ternary ester exchange on medium-carbon-chain glyceride, high-melting-point fat and linolenic acid grease, and performing ternary ester exchange on the medium-carbon-chain glyceride, the high-melting-point fat and the linolenic acid grease under the conditions of temperature and stirring intensity by taking lipase as a catalyst, so as to obtain the special grease base oil for the functional food in one step. The special grease base oil for for the functional food is wide in melting range, can remarkably improve in-vivo glucose and lipid metabolism disorder, balance and supplement in-vivo necessary and functional fatty acids and quickly supplement energy, can meet the requirements of consumers, particularly, dietary and nutritional requirements of patients with metabolic syndromes such as overweight, obesity, fatty liver, hyperlipidemia, hyperglycemia, hypertension, hyperblood viscosity, hyperuricemia and hyperinsulinemia and athletes can be met, and the special grease base oil can be widely applied to grease powder, margarine and sports nutritional foods.
Owner:NANCHANG UNIV
Environment-friendly trace lubricant and preparation method thereof
ActiveCN111154542AImprove the lubrication effectPromote degradationLubricant compositionSucroseIsostearyl alcohol
The invention provides a lubricant composition which is characterized by being prepared from lac eleostearic acid and fatty acid, wherein the molar ratio of the lac eleostearic acid to the fatty acidis 1:(1-2). The prepared lubricant composition is lac eleostearic acid fatty acid ester, is a good nonionic surfactant and lubricant, and has good lubricating performance; meanwhile, the biodegradability is good, and the environment-friendly effect is achieved. The invention also provides a trace lubricant prepared from the lubricant composition, and the trace lubricant is characterized by being prepared from the following components in percentage by weight: 30-40% of the lubricant composition, 20-30% of sophorolipid, 10-20% of polysucrose fatty acid ester, 5-10% of castor oil sodium sulfonate, 5-10% of isostearyl alcohol, and the balance being deionized water. The prepared trace lubricant can meet the requirements of lubrication cooling, extreme pressure wear resistance and rust prevention in metal processing; and the usage amount of the lubricant can be saved by 90% or more when the trace lubricant is matched with a minimal quantity lubrication device.
Owner:上海贝能环保科技有限公司
Methods for analysis of isomeric lipids
ActiveUS20150316507A1Allow separationEasy to separateSamples introduction/extractionMaterial analysis by electric/magnetic meansLipid formationPolyketide
A method for analyzing a sample that contains a plurality of lipid isomers is described that involves forming one or more lipid metal ion adducts and transporting the one or more lipid metal ion adducts through a Mix of POPC+OPPC differential mobility spectrometer to cause separation of the one or more lipid metal ion adducts from each other. The lipid isomers can be chosen, for example, from fatty acids, glycerolipids, glycerophospholipids, sphingolipids, saccharolipids, polyketides, sterol lipids, and prenol lipids. Particular examples include phosphatidylcholine regioisomers such as 1-palmatoyl-2-oleoyl-sn-phosphatidylcholine (POPC) and 1-oleoyl-2-palmatoyl-sn-phosphatidylcholine and triacylglycerols containg palmetic and oleic acid groups. The metal chosen can include a cationization reagent that contains sodium, potassium, silver or lithium.
Owner:DH TECH DEVMENT PTE
Microbial pesticide granule containing trehalose lipid as well as preparation method and application of microbial pesticide granule
PendingCN113243363AGood dispersionPlay the role of film protectionBiocidePlant growth regulatorsMicroorganismActive agent
The invention relates to a microbial pesticide granule containing trehalose lipid. The microbial pesticide granule comprises the following components in parts by weight: a phase-B component: 85-95 parts by weight of a granule carrier; a phase B component: 0.1-10 parts by weight of mother powder of microbial pesticide active ingredients; and a phase-C component: 0.1-3 parts by weight of functional slurry, and the functional slurry comprises the following components in parts by weight: 1-10 parts by weight of a binder, 1-20 parts by weight of an inducer, 1-20 parts by weight of a trehalose lipid surfactant, 0.1-5 parts by weight of warning coloration and the balance of water, totaling 100 parts by weight. According to the microbial pesticide granule containing trehalose lipid, trehalose lipid is used as an auxiliary agent and has excellent surface activity and interface activity, and trehalose lipid is a biological source surfactant, so that the biological activity of thalli in microbial powder is guaranteed, and effective components of microorganisms can be quickly and uniformly distributed on the surface of a particle carrier, which is beneficial to rapid colonization of thalli of the microbial granules in soil, promotion of plant growth, improvement of crop growth traits and improvement of quality, meanwhile, the trehalose lipid has good corrosion resistance, radiation resistance, drying and dehydration resistance protection and the like, great convenience is brought to storage, transportation and use of the microbial pesticide granules, and the storage period is guaranteed.
Owner:TIANJIN HIGHPOINT PLANT PROTECTION
Application of pharmaceutical adjuvant, sophorolipid, in field of medicine
InactiveCN107737340AHigh drug loading rateConvenient sourceOrganic active ingredientsPharmaceutical non-active ingredientsBiocompatibility TestingPharmaceutical formulation
The invention discloses an application of a pharmaceutical adjuvant, sophorolipid, in the field of medicine. Sophorolipid can be used as a pharmaceutical adjuvant in pharmaceutical production, and isnatural and nonhazardous, good in biocompatibility, strong in surface activity, dispersing capacity and emulsifying capacity, and capable of remarkably improving the stability of a main drug and the drug loading capacity and directly prolonging the drug storage time. Sophorolipid contains any one of lactone type sophorolipid and acid type sophorolipid or a mixture of the two in any ratio. The pharmaceutical adjuvant, sophorolipid, can be used for preparation of micro emulsion, submicron emulsion, lipidosome, microcapsules, magnetic medicine preparations or other preparations or other intramuscular injection or intravenous injection preparations with a surfactant. By adding the pharmaceutical adjuvant into preparation systems of different dosage forms with the proportion of 0.05%-3%, dosageforms meeting requirements can be prepared; the drug loading capacity and the preparation storage time are both obviously superior to those of a conventional surfactant, Tween 80, the adverse reaction occurring rate is lower than that of Tween 80, and therefore, the pharmaceutical adjuvant, sophorolipid, is an excellent natural microbial pharmaceutical adjuvant.
Owner:HEFEI UNIV OF TECH +1
Huidouba polysaccharide and preparation method thereof
InactiveCN105906737AThe preparation method is safe and non-toxicReduce energy consumptionOrganic active ingredientsMetabolism disorderUltrafiltrationEthanol precipitation
The invention belongs to the fields of health foods and medicines and discloses a Huidouba polysaccharide and a preparation method thereof. The preparation method comprises the steps of extracting Huidouba as a raw material with hot water, carrying out ethanol precipitation to obtain rough Huidouba polysaccharide, carrying out activated carbon decoloration, removing protein by virtue of a Sevage reagent, carrying out separation and purification by virtue of a ultrafiltration technique, and screening to obtain a Huidouba polysaccharide 2 with relatively low molecular weight, wherein the peak molecular weight Mp is 6277Da, the weight-average molecular weight Mw is 9703Da, and the number-average molecular weight Mn is 7144Da. By virtue of the preparation method, the Huidouba polysaccharide 2 can be efficiently prepared through separation, is capable of remarkably reducing blood glucose of type 2 diabetes KKAy mice, glycosylating hemoglobin, improving glucose tolerance and glucolipid metabolism, has an in-vitro antioxidation effect and is applicable to the preparation of health Huidouba polysaccharide foods and medicines with the hypoglycemic effect.
Owner:SOUTH CHINA UNIV OF TECH +1
Methods for analysis of isomeric lipids
ActiveUS9360455B2Allow separationEasy to separateSamples introduction/extractionMaterial analysis by electric/magnetic meansLipid formationPolyketide
Owner:DH TECH DEVMENT PTE
Biosynthetic composite oil-displacing agent and application thereof
ActiveCN111334275ALow critical micelle concentrationStrong crude oil emulsification abilityFluid removalDrilling compositionRhamnolipidEmulsion
The invention relates to a biosynthetic composite oil-displacing agent and application thereof. The oil-displacing agent is prepared from the following raw materials in percentage by weight: 40-50% ofsophorolipid fermentation liquor; 10 to 20 percent of rhamnolipid fermentation liquid; 0.5 to 2 percent of sclerotium rolfsii polysaccharide; 1-10% of micron-sized beet waste molasses; 0.05-0.2% of astabilizing agent; remaining water. The oil-displacing agent provided by the invention can enable an oil film adhered to the surface of a rock to be quickly stripped and residual oil retained by water power to fall off, dispersed oil drops are promoted to converge, start to flow and migrate, emulsified emulsion and polysaccharide components can play a role in profile control and displacement, thewater-displacing swept volume is enlarged, the oil-displacing efficiency and the oil-washing efficiency are improved, and the final recovery ratio is increased.
Owner:陕西中诺油气科技有限公司 +1
Medicine for relieving glucose and lipid metabolism disorder and improving vascular function and preparing method for medicine
InactiveCN107349196AImprove protectionGood effectOrganic active ingredientsMetabolism disorderSalvianolic acid BThrombus
The invention belongs to the technical field of medicine and pharmacology, and discloses a medicine for relieving glucose and lipid metabolism disorder and improving the vascular function and a preparing method for the medicine. The medicine for relieving glucose and lipid metabolism disorder and improving the vascular function is salvianolic acid B. The molecular formula of salvianolic acid B is C36H30O16. The preparing method for the medicine for relieving glucose and lipid metabolism disorder and improving the vascular function comprises the following steps that radix salviae miltiorrhizae medicinal materials are smashed into fine powder and are sieved through a 20-60-mesh sieve; an ethanol solution is added into the fine powder, the fine powder is soaked under the temperature less than 5 DEG C, ultrasonic extracting is conducted, and the extraction process temperature is lower than 25 DEG C; centrifuging is conducted on extracted liquid, filtering is conducted, ethanol is recovered after pressure reducing till the extracted liquid has no alcohol smell, and the extracted liquid is concentrated and filtered; and the extracted liquid is clarified, enrichment is conducted through macroporous resin first, then chromatographic column chromatography purifying is conducted, freezing and drying are conducted, and a salvianolic acid B extract substance is obtained. The medicine for relieving glucose and lipid metabolism disorder and improving the vascular function has the good protective effect on myocardial infarction and also can obviously relieving injuring of myocardial ischemia / reperfusion; thrombus is prevented from forming by anti-platelet aggregation; microcirculation is improved; and anti-oxidation injury is avoided.
Owner:成都医学院第一附属医院
Bifidobacterium bifidum capable of reducing fat, relieving hyperglycemia and regulating intestinal immunity and application of bifidobacterium bifidum
ActiveCN114686405AImprove resistance indexLower levelMilk preparationSugar food ingredientsBiotechnologyGut immunity
The invention relates to the technical field of microorganisms, in particular to bifidobacterium bifidum capable of reducing fat, relieving hyperglycemia and regulating intestinal immunity and application of the bifidobacterium bifidum. The preservation number of the bifidobacterium bifidum B11 is CGMCC (China General Microbiological Culture Collection Center) No.24381. The strain has good tolerance to gastric acid environment and bile salt and can effectively improve glucose and lipid metabolism disorder phenomena induced by obesity and the like, and viable thalli, inactivated thalli or metabolites of the bifidobacterium bifidum B11 have the capacity of improving constipation or repairing intestinal mucosal barriers, so that the bifidobacterium bifidum B11 can be used for preparing the oral preparation for treating constipation. Meanwhile, the organism immunity can be remarkably improved by viable thalli or inactivated thalli.
Owner:河北一然生物科技股份有限公司
Bifidobacterium longum 070103 with effects of remarkably reducing blood sugar and blood fat by targeting glucokinase and application of bifidobacterium longum 070103
The invention discloses bifidobacterium longum 070103 capable of remarkably reducing blood sugar and blood fat by targeting glucokinase and application of the bifidobacterium longum 070103. The preservation number of the Bifidobacterium longum 070103 is GDMCC (China General Microbiological Culture Collection Center) NO: 62526, and the preservation number of the Bifidobacterium longum 070103 is CGMCC NO: 62526. The bifidobacterium longum 070103 is separated from intestinal flora of healthy people, when the bifidobacterium longum 070103 is used for fermenting milk, the bifidobacterium longum 070103 has an activation effect on human liver glucokinase in vitro, in addition, the strain is derived from excrement of the healthy people and has no toxic or side effect on the human body, and meanwhile, the whole genome sequencing analysis finds that the strain is free of toxic genes, so that the bifidobacterium longum 070103 can be used for fermenting milk. Compared with traditional medicines for treating glucose and lipid metabolism disorder metabolic diseases such as obesity and type 2 diabetes mellitus, the pharmaceutical composition has certain advantages. The strain can be used for preparing probiotic fermented milk and has a wide market prospect.
Owner:GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY +2
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