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63 results about "Corydalis edulis" patented technology

Medicament for treating gout and its preparation method

The invention discloses a medicament for treating gout. The medicament is a Tibetan medicine and is also called Shisiwei Tongfengding, which is composed of an active component or is composed of active ingredients and pharmaceutically acceptable accessories. The active component is prepared from Tinospora sinensis Merr, (pitted) Terminalia chebula Retz., Acorus calamus L., Semen Cassiae, Corydalisimpatiens (Pall.) Fisch, (pitted) Fructus Terminaliae Billericae, frankincense (processed), ambrette, benzoin, acaciae catechu, Yanjinggao, (pitted) Phyllanthus emblica L., radix aucklandiae, and copper ash (processed) in certain weight proportion. The medicament can be prepared into any forms of common preparations for oral administration. With the functions of dispelling wind, eliminating dampness, diminishing inflammation, relieving pain and removing yellow water, the medicament provided in the invention can be used for treating arthritis, rheumatoid arthritis, gout, arthrocele, pain and deformation of limbs as a result of arthralgia diseases, stiff limbs, and yellow water accumulation, etc.
Owner:青海久美藏药药业有限公司

Use of protoberberine alkaloid in preparing against bacterial resistance medicament

The invention discloses an application of protoberberine alkaloid to prepare anti-drug tolerant bacterial drug, in particular to an application of compound coptisine, dehydrokaweidin and dihydroapokaweidin in the anti-drug tolerant bacterial drug, which is characterized by the following: extracting protoberberine from Corydalis saxicola Bunt. of Corydalis of Papaveraceae; displaying obvious inhibition for MRSA in the clinic through pharmacological test; using the compound protoberberine alkaloid as active component to make the drug to treat anti-drug tolerant bacterial drug.
Owner:成都军区昆明总医院

Method for controlling quality of corydalis tuber and preparation thereof and drug effect thereof by using finger print

The invention relates to a fingerprint map for controlling the quality and efficacy of rhizoma corydalis and preparation of the rhizoma corydalis and a preparation method of the fingerprint map. The invention discloses that the fingerprint map is one of anti-myocardial ischemic active site in the rhizoma corydalis, and the active site mainly comprises quaternary ammonium base components, wherein, columbamine, 13-methyldehydrocorydalmine, dehydrocorybulbine, palmatine, dehydrocorydaline are the main five components of quaternary ammonium base. The fingerprint map can identify the authenticity of samples and evaluate the quality and efficacy of the rhizoma corydalis or the preparation thereof, so that the quality of the rhizoma corydalis and the preparation thereof have real controllable standards, so as to ensure the product quality to be stable. The method has the advantages of being simple to operate and being accurate and reliable, which is applicable to controlling the quality and efficacy of the rhizoma corydalis and the preparation thereof.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI

Medicine for treating Qi-stagnation and blood stasis type chloasma and preparation method thereof

The invention discloses a medicine for treating Qi-stagnation and blood stasis type chloasma and a preparation method thereof. The medicine is prepared by eclipta, caulis sargentodoxae, large-leaved gentian, gynostemma pentaphylla, fructus aurantii, nux prinsepiae, testiset penis phocae, iris ensata thumb, hippocampus, angelica, rhizoma sparganii, curcuma zedoary, rhizome of glabrous greenbrier, moutan bark, rhizoma alismatis, rhizoma anemarrhenae, corydalis bowerihemsl., cortex phellodendri, cortex lycii radicis, herba melastomatis dodecandri, bamboo fern, pericarpium citri reticulatae, kohlrabi, rhizoma cyperi, melastoma sanguineum, radix paeoniae rubra, impure mirabilite, polygonum sagittatum, euphorbia maculata, tuber fleeceflower stem, rubus hirsutus and viola variegate. The medicine provided by the invention has the effects of regulating vital energy and promoting blood flow and removing stasis and ecchymoses, is mainly used for treating the Qi-stagnation and blood stasis type chloasma, and has the advantages of being fast to take effect, high in effective rate, definite in curative effect, short in treatment course, low in price, and is free from toxic and side effects.
Owner:王竞鹏

Corydalis edulis extract, pharmaceutical composition containing same and uses thereof

The invention provides Corydalis edulis extract, prepared by a method comprising the following steps: (1), after crushing a Corydalis edulis plant, and extracting with alkaline ethyl alcohol or methyl alcohol to obtain an extract; (2), subjecting the extract obtained in step (1) to normal pressure or vacuum concentration to obtain concrete, or spray drying to obtain powder; (3), adding an acid solution into the concrete or powder obtained in step (2), filtering to obtain an acid aqueous solution, adding an alkaline solution to the acid aqueous solution to obtain an alkali treated solution; (4), adding an organic solvent to the alkali treated solution obtained in step (3), vacuum recycling the organic solvent after extracting to obtain Corydalis edulis total alkaloids crude extract. The Corydalis edulis extract or a pharmaceutical composition containing the extract can be used to prepare pharmaceuticals for preventing and / or treating diseases caused by glucose and lipid metabolism disorder.
Owner:BEIJING UNIV OF CHINESE MEDICINE

Corydalis ochotensis total alkaloid and preparation method and medicinal application thereof

The invention relates to a corydalis ochotensis total alkaloid and a preparation method and a medicinal application thereof. The corydalis ochotensis total alkaloid is prepared by the following methods: grinding corydalis ochotensis into coarse powder; adding sulfuric acid solution with a concentration of 0.1-5% for soaking the coarse powder; then carrying out extraction by the sulfuric acid solution with a concentration of 0.1-5% by means of percolation; adjusting pH value of percolation liquid to 5-8 by NaOH solution; applying macroporous resin, eluting the percolation liquid by NaOH solution with a concentration of 1-10% until effluent liquid becomes almost colorless; washing the percolation liquid until the pH value of the percolation liquid ranges from 7 to 9; eluting the percolation liquid by ethanol with a concentration of 40% until the effluent liquid becomes colorless; eluting the percolation liquid by ethanol with a concentration of 80-95% until no alkaloid reactions occurs; and finally recovering ethanol by eluent and drying.The invention also relates to the application of the corydalis ochotensis total alkaloid in preparing medicine for improving memory function and treating senile dementia.Being a common medicinal material in Changbaishan Mount in China, the corydalis ochotensis is in existence in large quantities; therefore development of such a medicinal material is of positive significance.
Owner:JILIN UNIV

Traditional Chinese medicine preparation for treating heat stroke and preparation method thereof

The invention discloses a traditional Chinese medicine preparation for treating heat stroke and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following medicinal materials: scutellaria baicalensis, urtica laetevirens, soapstone, japonese pearlwort herb, amomum cardamomum, tetrapanax papyriferus, tibet velvetplant, coptis chinensis, tinospora sinensis, rhizoma anemarrhenae, radix scrophulariae, brunon larkspur herb, cortex moutan, honeysuckle, gordon euryale, agastache rugosus, mangnolia officinalis, sal ammoniac, citrullus vulgaris schrad, lotus leaf, all-grass of annual saltmarsh aster, sweet wormwood, schefflera pauciflora, Chinese waxgourd peel, acanthophyllous shield fern herb, acorus tatarinowii, longicorn larva, red yam rhizome, radix cynanchi atrati, jasminum giraldii diels, kelie (Chinese character) corydalis, walton lepisorus, panicum repens, common mappianthus stem and zanthoxylum avicennae. The traditional Chinese medicine preparation has the beneficial effects that the traditional Chinese medicine preparation disclosed by the invention has the efficacies of clearing summer-heat and tonifying qi, and inducing resuscitation and has the characteristics of being quick in effect taking, high in efficiency, accurate in curative effect, high in safety, free of toxic and side effects, short in treatment course, simple and convenient in preparation process, low in cost and the like, the pharmacological effect is direct to the lesion, the drug resistance is not easily generated, and the heat stroke does not easily reappear after being cured.
Owner:QINGDAO BAIHUIZHIYE BIOTECH

Chicken feed capable of promoting growth and improving disease resistance and meat quality

The invention discloses a chicken feed capable of promoting growth and improving disease resistance and meat quality. The chicken feed is prepared from the following raw materials: corn, sorghum, soybean meal, mung beans, medulla stachyuri, common nandina fruit, fructus polygoni orientalis, corydalis impatiens, Chinese mahonia, copperleaf, pterocephalus hookeri heck, root of sambucus chinensis, dogbane leaf, exocarpium, angelica decursiva, fistular onion seed, plum blossom, air potato, galanga galangal seed, radix onosmatis, wild carrot fruit, akebia fruit, papermulberry fruit, cape jasmine fruit, locus leaves, common anemarrhena rhizome, fleeceflower root, spina date seed, hemp seed, radix rehmanniae, mulberry twigs, figwort root, dwarf lilyturf tuber, pagoda tree flower, garden balsam and chicken yolk. Compared with the prior art, the chicken feed has the beneficial effects that the disease resistance and healthy survival rates of chicken are greatly improved; the growth speeds of chicken are high; the quality and taste of chicken are greatly improved; the safety factors are high; the chicken feed does not have negative effects on human health; the used raw materials are cheap and accessible, thus greatly reducing the production cost.
Owner:郑志保

Traditional Chinese medicine composition for treating cerebral thrombosis and preparation method of composition

The invention relates to the field of traditional Chinese medicines, particularly to traditional Chinese medicine composition for treating the cerebral thrombosis and a preparation method of the composition. The composition comprises components in parts by weight as follows: radix astragali, angelicae sinensis, white peony roots, fructus liquidambaris, cassia bark, centipedes, scorpions, safflower, pubescent angelica roots, ground beetles, roots of pseudo-ginseng, longan pulp, salvia miltiorrhiza, common selfheal fruit-spike, oriental waterplantain rhizome, gastrodia rhizome, ternate pinellia rhizome, dodder seeds, corydalis impatiens, emblic leafflower fruits, anomalous Artemisia, bear gall powder, bombyx batryticatus, Chinese clematis roots, suberect spatholobus stems, bile arisaema, licorice roots, lumbricus, chrysanthemums, peach kernels and fructus aurantii immaturus. The composition has functions of promoting blood circulation, removing blood stasis, resisting thrombus and freeing vessels and has the significant curative effect on the cerebral thrombosis.
Owner:QINGDAO MUNICIPAL HOSPITAL

Traditional Chinese medicine for treating respiratory disease of livestock and preparation method thereof

The invention discloses a traditional Chinese medicine for treating respiratory disease of livestock and a preparation method thereof. The traditional Chinese medicine comprises five traditional Chinese medicinal materials of herba violae, turkey corn, aster, herba ephedra and radix scutellariae. The traditional Chinese medicine can be effectively used for treating diseases of swine enzootic pneumonia, swine contagious pleuropneumonia, porcine reproductive and respiratory syndrome, swine plague, swine influenza, infectious bronchitis of chicken, infectious laryngotracheitis of chicken and thelike, and has the advantages of environment protection without toxic and side effects, simple preparation process, low production cost and the like.
Owner:BEIJING DABEINONG ANIMAL HEALTH TECH

Preparation method of corynoloxine

The invention discloses a preparation method of corynoloxine, which is simple and easy to operate and less in pollution. The preparation method of the corynoloxine comprises the following steps: (1) preparing dry incised corydalis herb, smashing into 20-80 meshes, extracting in a CO2 supercritical extraction tank, introducing liquid CO2 at a flow rate of 1-4ml / min for one gram raw material while introducing chloroform as a cosolvent at a flow rate of 1-4ml / min / g, and resolving to obtain an extractant, wherein a raw material extraction temperature is 30-50 DEG C, pressure is 15-25MPa, and extraction time is 1-3 hours; and 2) dissolving the extractant with a 70% acetone solution, passing through a calcium peroxide short column, collecting liquid passing through the short column and concentrating, then separating by adopting a high-speed countercurrent chromatographic instrument, carrying out online monitoring by adopting an ultraviolet detector, collecting fractions, and carrying out reduced pressure drying, thus the corynoloxine is obtained. When the preparation method of the corynoloxine is adopted for preparing the corynoloxine, the obtained corynoloxine product is high in purity, and industrial production is easy to realize.
Owner:NANJING TONGZE AGRI SCI & TECH

Traditional Tibetan medicine for treating hyperlipidemia and preparation method thereof

The invention discloses a traditional Tibetan medicine for treating hyperlipidemia. The traditional Tibetan medicine is composed of active components or composed of active components and auxiliary material acceptable in pharmacy, wherein the active components are prepared, by weight, by amomum tsao-ko, corydalis impatiens, fructus piperis longi, herpetospermum, amomum kravanh, sandalwood, tabasheer, agilawood, pomegranate seed and flowers carthami. The traditional Tibetan medicine can be prepared into any commonly-used oral agent type. The traditional Tibetan medicine has effects of dehumidification, phlegm eliminating, blood activating, stasis removing and venation warming and penetrating. The traditional Tibetan medicine is used for chills and fever complication, weakness of the spleen and the stomach, venation blocked by bacon and the hyperlipidemia, and also can be used for auxiliary treatment of cardiovascular and cerebrovascular diseases caused by the hyperlipidemia and atherosis.
Owner:青海久美藏药药业有限公司

Medical efficient wound disinfectant and preparation method thereof

InactiveCN109010531ASignificant strong bactericidal functionHas a cleaning effectAntipyreticAntisepticsTreatment effectDisinfectant
The invention relates to the technical field of a medical article, in particular to a medical efficient wound disinfectant and a preparation method thereof. The medical efficient wound disinfectant isprepared from the following raw materials: leptospermum scoparium, saffron crocus, humifuse euphorbia herb, geranium wilfordii, Chinese torreya, edelweiss, fructus cnidiif, corydalis edulis, medicinal alcohol, span and a proper amount of distilled water. The prepared disinfectant has prominent strong sterilization functions such as antivirus and antimildew; the disinfectant has the obvious inhibition effect on staphylococcus aureus, beta streptococcus, apex pulmonis coccus and the like. The medical efficient wound disinfectant can effectively disinfect the inside and outside of the wound; thesterilization effect is good; the infection probability of the wound can be reduced; meanwhile, a certain cleaning effect is achieved. The prepared disinfectant has the efficacy of treating pain fromrheumatism, ulcer and traumatic injury, and also has an obvious treatment effect on peculiar smell, and skin inflammation, pruritus and desquamation caused by vulvae pruritus and moistness.
Owner:HUBEI ZANBO INFORMATION TECH CO LTD

Corydalis impatiens total alkaloid extractive for preparing anti-cancer drugs and application thereof

ActiveCN103623066AAnti-breast cancerOvarian cancerOrganic active ingredientsAntineoplastic agentsStomach cancerLung cancer
The invention discloses corydalis impatiens total alkaloid extractive for preparing anti-cancer drugs. The content of total alkaloids in the discloses corydalis impatiens total alkaloid extractive is not less than 50wt percent; the disclosed corydalis impatiens total alkaloid extractive comprises 10 to 12wt percent of protopine, 8 to 10wt percent of alpha-bicuculline and 10 to 15wt percent of ochotensimine; the extracting steps of the extractive comprise grinding corydalis impatiens drugs, performing reflux extraction to the corydalis impatiens drugs through saturated alkaline ethyl alcohol or saturated alkaline methyl alcohol, and concentrating and trying the corydalis impatiens drugs, so as to obtain corydalis impatiens extractive, then dissolving and filtering the extractive through acid solution, adding alkali solution into filter liquor, and adjusting the pH value of the solution to be 9 to 10, so as to obtain acid and alkali treated fluid, adding organic solvent into the acid and alkali treated fluid, so as to perform extraction, obtaining corydalis impatiens total alkaloid crude extract, and then purifying the corydalis impatiens total alkaloid crude extract, so as to obtain the corydalis impatiens total alkaloid extractive. The corydalis impatiens total alkaloid extractive obtained through the method has effects of breast cancer resistance, ovarian cancer resistance, stomach cancer resistance and lung cancer resistance.
Owner:SHANDONG JINHE DRUG RES DEV

Tibetan medicine for treating hypertension and preparation method thereof

The invention discloses a tibetan medicine for treating hypertension, which is composed of active ingredients or active ingredients and pharmaceutically acceptable additives, wherein the active ingredients are prepared from agilawood, lagotisglauca, corydalis pygmaea, radix onosmatis, tinospora sinensis merr, elecampane, pleurospermum hookeri, flos pyrethri tatsienensis, caragana sinica, shellac,rubia wallichiana decne, gastrodia elata, fructus choerospondiatis, fruit of emblic leafflower and corydalis impatiens according to a weight ratio. The tibetan medicine can be prepared to any common oral medication dosage form. The tibetan medicine disclosed by the invention has the functions of soothing the nerves, quieting the heart and decreasing the blood pressure. The tibetan medicine is suitable for headache, dizziness, limb numbness, palpitation, dismay, tinnitus, insomnia and hypertension.
Owner:青海久美藏药药业有限公司

Tibetan medicinal preparation for treating essential hypertension and preparation method thereof

The invention relates to a Tibetan medicinal preparation for treating essential hypertension. The Tibetan medicinal preparation for treating the essential hypertension is prepared from the following raw medicinal materials in parts by weight: 100-200 parts of Tibetan caragana, 50-150 parts of Adhatoda Vasica Nees, 50-150 parts of Herba Lagotis, 50-150 parts of corydalis pygmaea, 50-150 parts of lignum rhamnellae ointment or 500-1500 parts of lignum rhamnellae and 80-180 parts of phyllanthus emblica. The Tibetan medicinal preparation for treating the essential hypertension has the effects of treating the essential hypertension and lowering blood pressure and can be used for preparing an antihypertensive drug.
Owner:TIBET QIZHENG TIBETAN MEDICINE

Traditional Chinese medicine preparation for treating acute cholecystitis and preparation method of traditional Chinese medicine preparation

InactiveCN104758466AHigh-qualityStrong and long-lasting effectDigestive systemPlant ingredientsAngelica Sinensis RootBiology
The invention discloses a traditional Chinese medicine preparation for treating acute cholecystitis. The traditional Chinese medicine preparation is prepared from the following main raw materials in parts by weight: 12-17 parts of rhizoma corydalis, 10-15 parts of daphne koreana, 9-15 parts of Yunnan swertia herb, 13-18 parts of christina loosestrife herb, 8-13 parts of veitch gentian herb with root, 12-18 parts of isodon serra, 9-13 parts of lushan mountain barberry, 9-15 parts of cinnamon, 13-20 parts of calamint, 12-15 parts of scarlet swertia herb, 8-13 parts of herb of lygodium japonicum, 11-17 parts of clove, 8-12 parts of corydalis impatiens, 15-20 parts of angelica sinensis and 12-17 parts of areneria kensuensis. The traditional Chinese medicine preparation has the efficacy of discharging the liver, regulating qi, benefiting gallbladder, relieving pain, warming the middle warmer, arresting vomiting, regulating qi and activating blood circulation, has an obvious curative effect on acute cholecystitis, and is capable of treating both symptoms and root causes of cholecystitis.
Owner:王玉玲

Medicine composition for treating spleen and stomach damp-heat type peptic ulcer and method for preparing medicine composition

InactiveCN105362843AImprove damp heat constitutionRegulate immune functionDigestive systemPlant ingredientsCirsiumSide effect
The invention discloses a medicine composition for treating spleen and stomach damp-heat type peptic ulcer and a method for preparing the medicine composition. The medicine composition comprises diaphragma juglandis, Cipadessa cinerasce-ns (Pell.) Hand.-Mazz., radix glycyrrhizae, asian butteflybush roots and leaves, filipendula palmata, violet, codonopsis pilosula, smilax stans, hedyotis diffusa, herb of largeserrate molsa, fructus chaenomelis lagenariae, clerodenrum bungei steud, polygonum hydropiper, textile screw pine shoot, michelia alba, pararuellia delavayana, cirsium vlassovianum, camellia oil, biondia henryi, fructus psoraleae, cynanchum glaucescens, loofah juice, delavay falsepanax herb, blumea, caulis clematidis armandii, panax notoginseng, radix fici simplicissimae, corydalis gigantea Trautv. & C.A. Mey. and hypericum attenuatum. The medicine composition and the method have the advantages that effects of regulating spleens, harmonizing stomachs, clearing heat, removing dampness, promoting qi circulation and strengthening the spleens can be realized by the medicine composition, the medicine composition is mainly used for treating the spleen and stomach damp-heat type peptic ulcer, the stomach mucosae can be protected, the damp-heat constitution of patients further can be effectively improved, immune functions of the bodies of the patients can be integrally regulated, the medicine composition can become effective fast and is high in efficiency, short in treatment course, free of toxic and side effects and low in cost, definite curative effects can be realized, and the like.
Owner:李孝国

Preparation method of tertiary amine alkali components in rhizoma corydalis

The present invention provides a preparation method of tertiary amine alkali components in rhizoma corydalis. The preparation method of the provided components is as follows: berberine quaternary ammonium alkali in the rhizoma corydalis extract is reduced into protoberberine tertiary amine alkali, wherein two quaternary ammonium alkalis with highest content in the rhizoma corydalis, namely palmatine and dehydrocorydaline, are respectively reduced into tetrahydropalmatine and corydaline, pH of a reaction supernatant is adjusted to be neutral, dry-steaming is conducted, and drying is conducted after desalting to obtain the tertiary amine alkali components, wherein a total alkali content is 50% or more. The preparation method is simple in process, high in efficiency, high in recovery rate andlow in production cost, and provides a good technical scheme for developing safe, effective and controllable rhizoma corydalis alkali component preparations.
Owner:TAIZHOU GUOKEHUAWU BIOMEDICAL TECH CO LTD

Production method of vinegar rhizoma corydalis decoction pieces

The invention discloses a production method of vinegar rhizoma corydalis decoction pieces, and belongs to the technical field of traditional Chinese medicine decoction pieces. The method includes thefollowing steps that rhizoma corydalis is cleaned, dewatered and dried; vinegar is added for covered moistening, and the rhizoma corydalis is steamed until the vinegar is completely absorbed; the finished product is dried and discharged after it is detected that the finished product is qualified. The method is easy to operate, reduces the waste of the vinegar, improves the utilization of the vinegar, can be used for evenly heating the rhizoma corydalis, and improves the quality and drug effect of the rhizoma corydalis.
Owner:台州仁民中药有限公司

Pharmaceutical composition for treating stomach cancer and preparation method thereof

The invention discloses a pharmaceutical composition for treating stomach cancer and a preparation method thereof. The pharmaceutical composition is prepared from crude drugs comprising mature seeds of entada phaseoloides, whole herb of corydalis hendersonii, whole herb of ajuga lupulina, sciadopitysin, taraxerol and inokosterone according to ratio, can be prepared into various dosage forms according to a conventional preparation process and has a remarkable curative effect for treating the stomach cancer.
Owner:JINAN XINGYI MEDICAL TECH

CDL (corydalmine) medicine composition for preventing and treating opioid analgesic pain relieving tolerance

The present invention discloses the new application of Corydalis CDL (CDL) in the field of analgesic drugs, and specifically discloses the application of CDL in the preparation of drugs for preventing or treating analgesic tolerance of opioid analgesic drugs. The corydalis dammine is used in combination with opioids, or used in compound preparations with opioids, which can enhance its analgesic effect and prevent or alleviate opioid tolerance in the course of chronic opioid treatment. This effect is achieved by inhibiting opioid-induced excessive activation of spinal cord microglial cells, and inhibiting opioid-induced excessive up-regulation of p-P38, p-ERK and p-JNK.
Owner:CHINA PHARM UNIV +1

Sound-insulation and anti-fouling wallpaper and preparing method thereof

The invention discloses a sound-insulation and anti-fouling wallpaper. The sound-insulation and anti-fouling wallpaper is prepared from, by weight, 20-24 parts of white glues, 23-25 parts of rosin, 120-140 parts of paper pulp, 10-16 parts of a mould-proof agent, 10-14 parts of an anti-fouling agent and 1-3 parts of an interfacial modifier in a mixed mode; a fungus-proof agent is prepared from, by weight, 20-30 parts of pomegranate peels, 11-15 parts of whole herbs of corydalis bungeana and 8-13 parts of asparagus officinalis; the anti-fouling agent is prepared from, by weight, 12-16 parts of hexamethyldisilane, 2-4 parts of polysiloxane and 6-8 parts of sodium borate; the interfacial modifier is prepared from castor oil. The sound-insulation and anti-fouling wallpaper is simple in preparing technology, the raw materials are easy to obtain, the cost is low, the sound-insulation, anti-fouling and anti-mildew properties are good, and the service life of the wallpaper is greatly prolonged.
Owner:ANHUI SOYA DECORATIVE MATERIALS

Preparation method of quaternary ammonium base component in corydalis tuber extract

The invention provides a preparation method of a quaternary ammonium base component in a corydalis tuber extract. According to the preparation method, protoberberine tertiary amine bases in a corydalis tuber extract are oxidized into berberine quaternary ammonium bases, wherein the two protoberberine tertiary amine bases with the highest content, such as tetrahydropalmatine and corydaline, in corydalis tuber are respectively oxidized into palmatine and dehydrocorydaline; after the reaction is completed, filtering is performed; and the supernatant is concentrated and dried to obtain the corydalis tuber extract component rich in the berberine quaternary ammonium compound, wherein the total alkali content reaches more than 50%. According to the invention, the preparation method is simple in process, efficient, high in recovery rate and low in production cost, and provides a good technical scheme for safe, effective and controllable development of corydalis tuber alkaloid component preparations.
Owner:TAIZHOU GUOKEHUAWU BIOMEDICAL TECH CO LTD

Preparation method of corydalis incisa amine

The invention discloses a preparation method of corydalis incisa amine. The preparation method comprises the following steps of: (1) taking hypecoum leptocarpum, crushing the hypecoum leptocarpum, adding ethanol for extraction, filtering and concentrating the hypecoum leptocarpum into thick paste with the relative density of 1.1-1.3; (2) taking the thick paste in the step (1), loading the thick paste on a macroporous resin column, sequentially eluting with water and ethanol, collecting an ethanol elution part, concentrating and drying to obtain a hypecoum leptocarpum refined extract; and (3) dissolving the hypecoum leptocarpum refined extract obtained in the step (2) in methanol, filtering, separating filtrate by using preparative high performance liquid chromatography, collecting a chromatographic peak fraction with the highest response value in a preparative chromatogram, concentrating and drying the fraction to obtain the corydalis incisa amine. The purity of the corydalis incisa amine prepared by the preparation method disclosed by the invention is greater than 98%.
Owner:CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST

Traditional Chinese medicine (TCM) preparation for treating infantile anorexia

The invention discloses a traditional Chinese medicine (TCM) preparation for treating infantile anorexia. The TCM preparation is prepared from the following TCMs in parts by weight: 10-20 parts of sandwort, 10-20 parts of benzoin, 5-15 parts of semen hertospermi, 5-15 parts of flos pyrethri tatsienense, 5-15 parts of negundo chastetree fruit, 3-9 parts of herba gentianopsis paludosae, 3-9 parts of solms-laubachia pulcherrima, 3-9 parts of broomjutre sida herb, 3-9 parts of root of damnacanthus indicus, 3-7 parts of ovate leaf holly bark, 3-7 parts of shortspike lagotis, 3-7 parts of huperzia serrata, 1-5 parts of longstamen onion bulb, 1-5 parts of herba corydalis, 1-5 parts of tinospora sinensis merr and 1-5 parts of leaf of Chinese coriaria. Through clinical application and observation, the TCM preparation can be used for effectively treating infantile anorexia, and has the advantages of definite curative effects, easiness in absorption, high effect taking speed, safety, reliability and no side effects.
Owner:朱玉芳

Zangsiwei Qingfei Mixture and Its Application in the Preparation of Drugs for Treating Respiratory Diseases

The invention belongs to the field of natural medicines, and in particular relates to a prescription of Tibetan Siwei Qingfei Mixture, which is the original medicine composed of rhododendron lanceolata, gentian flower, barberry bark and corydalis dwarf and an extract thereof. The research of the present invention has found that the combination of Rhododendron lanceolata, gentian flower, barberry bark and Corydalis dwarf can achieve synergy, effectively improve the anti-inflammatory effect, and improve the therapeutic effect of chronic obstructive pneumonia. In addition, It can also improve the repair function of lung injury.
Owner:湖南惜品医疗科技有限公司

Tibetan medicine compound for treating gastrointestinal diseases of calves and preparation method and application thereof

The invention relates to a Tibetan medicine compound for treating calf diarrhea and a preparation method thereof, and relates to the technical field of medicines. The Tibetan medicine compound is prepared from the following raw materials in parts by weight: 1-3 parts of barberry root, 1-4 parts of hippophae rhamnoides, 5 parts of myrobalan, 2 parts of dracocephalum tanguticum and 2 parts of corydalis pygmaea. The Tibetan medicine compound disclosed by the invention has the effects of inhibiting bacteria, stopping diarrhea and easing pain, also has the effect of reducing intestinal advancement rate, inhibits intestinal epithelial cell shedding, reduces mucosal edema, reduces inflammatory cell infiltration, promotes rapid healing of diarrhea, does not easily generate bacterial drug resistance, and does not influence animal production performance.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS

Tibetan medicine for treating hypertension and preparation method thereof

The invention discloses a tibetan medicine for treating hypertension, which is composed of active ingredients or active ingredients and pharmaceutically acceptable additives, wherein the active ingredients are prepared from agilawood, lagotisglauca, corydalis pygmaea, radix onosmatis, tinospora sinensis merr, elecampane, pleurospermum hookeri, flos pyrethri tatsienensis, caragana sinica, shellac,rubia wallichiana decne, gastrodia elata, fructus choerospondiatis, fruit of emblic leafflower and corydalis impatiens according to a weight ratio. The tibetan medicine can be prepared to any common oral medication dosage form. The tibetan medicine disclosed by the invention has the functions of soothing the nerves, quieting the heart and decreasing the blood pressure. The tibetan medicine is suitable for headache, dizziness, limb numbness, palpitation, dismay, tinnitus, insomnia and hypertension.
Owner:青海久美藏药药业有限公司
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