Tibetan medicine compound for treating gastrointestinal diseases of calves and preparation method and application thereof

A gastrointestinal disease and compound technology, which is applied in the field of Tibetan medicine compound and its preparation for the treatment of calf gastrointestinal diseases, can solve the problems of antibacterial, analgesic and anti-inflammatory drugs that have not been studied in detail, and achieve the goal of not being resistant to bacteria. Medicinal properties, promoting rapid healing, and reducing the effect of inflammatory cell infiltration

Active Publication Date: 2021-04-06
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it did not study the antibacterial, analgesic, anti-inflammatory effects of the drug in detail

Method used

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  • Tibetan medicine compound for treating gastrointestinal diseases of calves and preparation method and application thereof
  • Tibetan medicine compound for treating gastrointestinal diseases of calves and preparation method and application thereof
  • Tibetan medicine compound for treating gastrointestinal diseases of calves and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0039] The preparation of the Tibetan medicine compound for the treatment of calf diarrhea provided by the invention:

[0040] The Tibetan medicine compound formula is shown in Table 1, and the data in Table 1 are mass ratios.

[0041] Table 1 Tibetan medicine compound prescriptions with different ratios

[0042]

[0043]The preparation method of Tibetan medicine compound oral liquid:

[0044] (1) Take three needles, seabuckthorn, myrobalan, sweet orchid and corydalis, weigh them according to the proportion, wash with cold water to remove floating dust;

[0045] (2) Soak the medicinal material obtained in step (1) in cold water for 24 hours;

[0046] (3) In the airtight decoction machine, add the medicinal materials soaked in step (2), add 5-10 times the volume of water, and decoct in water for 2 hours at 115°C;

[0047] (4) collect step (3) decocted medicinal liquid, filter with four layers of gauze to obtain the filtrate;

[0048] (5) Add 5-10 times more water to the ...

Embodiment 6

[0055] Example 6, antidiarrheal, analgesic and antibacterial effects of Tibetan medicine compound

[0056] 1. Antibacterial effect research

[0057] Take Example 1 according to 200 grams of three needles, 300 grams of seabuckthorn, 500 grams of Myrobalan, 200 grams of Ganqing Qinglan, 200 grams of Corydalis dwarf, and embodiment 2 according to 300 grams of three needles, 30 grams of seabuckthorn, and 500 grams of Myrobalan , Ganqing Qinglan 200 grams, Dwarf Corydalis 200 grams, embodiment 3 according to three needles 200 grams, seabuckthorn 400 grams, myrobalan 500 grams, Ganqing Qinglan 200 grams, dwarf Corydalis 200 grams, embodiment 4 according to three needles 100 grams of needles, 300 grams of seabuckthorn, 500 grams of myrobalan, 200 grams of Ganqing Qinglan, 200 grams of Corydalis dwarf, embodiment 5 according to three needles 300 grams, 100 grams of seabuckthorn, 500 grams of myrobalan, 200 grams of Ganqing Qinglan, Corydalis dwarf 200 grams, the prepared Tibetan medi...

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PUM

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Abstract

The invention relates to a Tibetan medicine compound for treating calf diarrhea and a preparation method thereof, and relates to the technical field of medicines. The Tibetan medicine compound is prepared from the following raw materials in parts by weight: 1-3 parts of barberry root, 1-4 parts of hippophae rhamnoides, 5 parts of myrobalan, 2 parts of dracocephalum tanguticum and 2 parts of corydalis pygmaea. The Tibetan medicine compound disclosed by the invention has the effects of inhibiting bacteria, stopping diarrhea and easing pain, also has the effect of reducing intestinal advancement rate, inhibits intestinal epithelial cell shedding, reduces mucosal edema, reduces inflammatory cell infiltration, promotes rapid healing of diarrhea, does not easily generate bacterial drug resistance, and does not influence animal production performance.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a compound Tibetan medicine for treating calf gastrointestinal diseases and its preparation method and application. Background technique [0002] Gastrointestinal diseases cover diseases of the esophagus, stomach, small intestine, colon and rectum. The common main symptoms include rhythmic and periodic epigastric pain, diarrhea, hunger abdominal pain, acid reflux, fever, melena and bloody stool, gastrointestinal bleeding and intestinal obstruction etc. Gastrointestinal disorders are among the most common in humans, the most common of which include dysphagia, gastric ulcer, peptic ulcer, gastroparesis, delayed gastric emptying, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). Diarrhea is a symptom of intestinal diseases. It is mostly caused by disease factors, and intestinal diseases are the most common. Other common ones include acute fo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61K9/08A61P1/00A61P1/12A61P29/00A61P31/04
CPCA61K36/29A61K36/185A61K36/53A61K36/66A61K9/0095A61K9/0053A61P1/12A61P1/00A61P29/00A61P31/04A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00Y02A50/30
Inventor 张凯张康仇正英王磊张景艳王贵波郭志廷王学智李建喜
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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