502 results about "Phthalic acid ester" patented technology

An improved process of coating tacky or soft polymer pellets to maintain a free-flowing property, uses a liquid binder, in conjunction with an anti-tack or partitioning powder such as talc to prevent aggregation during storage. The binder is a non-volatile material such as an oil or plasticizer including triglycerides, mono- / di-glycerides, acetylated mono- / di-glycerides, fatty acids, epoxidized triglycerides, phthalates, benzoates, sebacates, lactates, citrates, mineral oils etc. Applications of this process include chewing gum bases, hot-melt adhesives, sealants, rubber masterbatches, powdered rubber, and other soft and tacky polymer materials.

The invention relates to a medical multifunctional polyvinyl chloride composite material which consists of polyvinyl chloride (PVC) resin powder, a nano modified material, a plasticizer, a stabilizer and a lubricant. In the formula, every 100 portions of PVC resin powder is added with 0.5 portion to 3 portions of nano modified material, 20 portions to 40 portions of phthalic acid ester, 10 portions to 30 portions of trimellitate, 10 portions to 30 portions of citrate, 5 portions to 10 portions of epoxidized soybean oil (ESO), 0.5 portion to 1 portion of calcium stearate (CaSt), 0.5 portion to 1 portion of zinc stearate (ZnSt) and 0.1 portion to 0.5 portion of silicon oil according to portions by weight. The nano modified material is nano silver-supported zinc oxide or nano silver-supported titanium dioxide and has the main effects of having anti-bacterial function and being capable of improving the physical properties of resins. The composite material has reasonable formula, stable performance, simple technology, nano antibacterial function and low dissolution performance of the plasticizer, and can be used for producing various medical apparatuses.

The invention relates to a preparation method for a compound fungus agent for specifically degrading an organic matter for a biological enhancing water treatment system. The compound fungus agent is added into a biological treatment process, has high biological activity, a stable effect and low cost, is easy to adsorb on the surface of a carrier and is difficult to lose. The preparation method issimple and practical, and has a short preparation period and low cost. The compound fungus agent comprises the following four strains: 20 to 30 percent of pseudomonas-stutzeri, 20 to 30 percent of pseudomonas putida, 10 to 20 percent of pseudomonas-pertucinogena and 30 to 50 percent of bacillus subtilis. The compound fungus agent is prepared by combining and screening the strains, performing slant culture and primary culture, mixing according to the proportion, and performing secondary cycle culture. The preparation method is widely used in a biological enhancing water treatment process, has a long-term and stable operation period, and has specific degradation ability for toxic and harmful organic pollutants such as halogenated hydrocarbons, phenol, benzoic acid, aromatics, polycyclic aromatic hydrocarbon, heterocyclic compounds, phthalic acid ester and the like.

Reactor grade thermoplastic polyolefins with high flowability and excellent surface quality comprising (A) 40-90 wt % of a propylene homo- or copolymer matrix with an MFR in accordance with ISO 1 133 (230° C., 2.16 kg load) of >200 g / 10 min and (B) 2-30 wt % of an elastomeric ethylene-propylene copolymer having an intrinsic viscosity IV (according to ISO 1628 with decalin as solvent) of ≦2.8 dl / g and an ethylene content of >50 to 80 wt % and (C) 8-30 wt % of an elastomeric ethylene-propylene copolymer having an intrinsic viscosity IV (according to ISO 1628 with decalin as solvent) of 3.0-6.5 dl / g and an propylene content of 50 to 80 wt %, the reactor grade thermoplastic polyolefins being obtainable by a multistage polymerization process with at least 3 polymerization steps in the presence of a catalyst system comprising (i) a Ziegler-Natta procatalyst which contains a trans-esterification product of a lower alcohol and a phthalic ester and (ii) an organometallic cocatalyst and (iii) external donor represented by formula (I) Si(OCH2CH3)3(NR1R2) wherein R1 and R2 can be the same or different a represent a hydrocarbon group having 1 to 12 carbon atoms, as well as the use of these reactor grade thermoplastic polyolefins and molded articles produced from them.

The invention discloses a capacitor film with low density polyethylene as substrate and a preparation method thereof. The capacitor film comprises the following raw materials by weight: 50-55 parts of LDPE (low density polyethylene), 20-25 parts of LLDPE (linear low density polyethylene), 10-15 parts of homo-polymer, 3-5 parts of epoxy linseed oil, 2-3 parts of polyvinyl alcohol, 1-2 parts of aluminum hydroxide, 1-2 parts of polyisobutylene, 8-12 parts of diatomite, 1-2 parts of ferrocene, 0.8-1.2 parts of poly-4-methyl-1-pentene, 5-10 parts of calcium carbonate, 2-4 parts of hydrotalcite, 1.3-1.8 parts of zinc dialkyl dithiophosphate, 0.4-0.6 part of phthalic acid ester, 0.4-0.7 part of smoke sheet rubber, 1-3 parts of zinc stearate and 0.9-1.3 parts of modified wood ash. The invention mainly adopts low density polyethylene assisted with linear low density polyethylene; and various accessories and additives are subjected to mixing and extrusion, blown film sizing and cutting to prepare the capacitor film. The preparation method is simple; and diatomite, hydrotalcite and modified wood ash are added into the raw materials at the same time to enhance barrier property and air tightness of the film; besides, the capacitor film has characteristics of good pressure resistance, impact resistance, high heat sealing strength, and good heat sealing performance.

The invention relates to a preparation method of an environmentally-friendly disposable polyvinyl chloride (PVC) glove, belonging to the fields of synthesis, application and processing shaping of high polymer materials. PVC paste resin is used as a raw material, a non-phthalic acid ester plasticizer, a non-heavy metal heat stabilizer and the like are used as the additives of an environmentally-friendly formula, and a calcium / zinc composite is used as the heat stabilizer to prepare the environmentally-friendly disposable PVC medical or civilian glove, wherein the plasticizer can be triisooctyl trimellitate (TOTM), dioctyl terephthalate (DOTP), biological oil-based ester, vegetable oil-based ester, fatty acid triglyceride, epoxy fatty acid ester or citrate ternary ester compounds. The invention provides the method for preparing the non-toxic and environmentally-friendly disposable PVC glove; and the prepared glove successfully passes the international SGS detection and the main properties of the product are obviously better than those of the similar PVC products in the market.

The invention discloses a food grade plasticizing polrvinyl chloride (PVC) glove and belongs to an environment-friendly food grade plasticizing PVC glove. The glove does not contain lead, cadmium and other toxic stabilizers, and phthalic acid ester plasticizer, has the advantages of high elasticity, high intensity and extremely low content of evaporation residues of n-heptane soluble substances, and can be used for the common food packaging industry, in particular contact fat type food industry with the high requirement, so that the application range of the food grade plasticizing PVC glove can be greatly widened. The food grade plasticizing PVC glove is prepared from the following raw materials in part by mass: 100 parts of emulsion method PVC resin, 40 to 80 parts of nitrile rubber liquid, 0 to 15 parts of vinyl terpolymer resin, 0 to 20 parts of polyester type plasticizer, 0 to 15 parts of aliphatic ester type plasticizer, 0.5 to 1.5 parts of compound stabilizer liquid, 0.1 to 0.5 part of antioxidant and 10 to 60 parts of organic solvent diluent.

The invention discloses a biodegradable plastic line for three-dimensional (3D) printing. The biodegradable plastic line comprises polylactic acid, impact modifier, plasticizer and an aid, wherein the impact modifier is compounded by one or more of acrylate impact modifiers and thermoplastic elastomer impact modifiers; the plasticizer is compounded by one or more of phthalic acid ester plasticizers, citrate plasticizers, epoxy plasticizers and lactate plasticizers; the aid comprises one or a mixture of more of a lubricating agent, an antioxidant and a chain extender. The material has high liquidity and dimensional stability, the requirements of a 3D printer on printing fluency and dimensional stability of the material are met, and the material is biodegradable, high in degradation rate, environmental friendly and pollution-free. Meanwhile, the material has a certain transparency, and the product printed by the 3D printer has semipermeability and is attractive in appearance and bright in color.

The invention discloses a method for quickly detecting dibutyl phthalate, which comprises the following steps of: a, constructing an inhibitory curve; and b, sample detection. Compared with the prior art, the method is high in sensitivity, quick and high in specificity, adopts simple method and consumes less time, is applicable to the quick analysis of environment pollutant DBP (Dibutyl Phthalate) and is also significant for the determination of phthalate.

Methanol is produced from bacterially oxidized waste methane by reaction with Pd+2, Cu+2 air, and molten phthalic anhydride in an entrained oxidizer generating half ester of methyl phthalate which is reaction distilled to prodtice methanol and recycle phthalic anliydride containing the Pd+2,Cu+2 phthalate catalyst.

C4-C7 secondary aliphatic alcohol esters of cyclohexanediacid are especially useful as plasticizers for PVC. In embodiments, these fast fusing plasticizers are useful in plastisol formulations to help improve the processability of flexible PVC material. In preferred embodiments these same plasticizers can be used in blends with other plasticizers, especially slower fusing plasticizers or plasticizers with reduced solvency, such as di-2-propylheptyl phthalate or di-isononyl cyclohexanedicarboxylic acid, to improve processability.

The invention provides a method for detecting various phthalic acid ester plasticizers at the same time. The method includes the steps that firstly, a sample is extracted and purified in an optimized QuEChERS pretreatment mode; secondly, analysis is carried out in a gas chromatography-tandem mass spectrometry mode; finally, accurate qualitative and quantitative analysis is carried out with an isotope internal standard method. The method can be applied to detecting twenty-three phthalic acid ester plasticizers in plant source character foods such as common Chinese cabbages, tomatoes, strawberries, grapes, shiitake mushrooms and agaric at the same time. By means of the method, the plasticizers introduced through external source ways are avoided to the maximum degree, the pretreatment step is simple, consumed time of solid-phase extraction and purification is shortened, and consumed solvents and argent compound losses of the solid-phase extraction and purification are reduced; the method has the advantages of being sensitive, accurate, good in stability, short in consumed time and easy to popularize; the method can be suitable for detecting mass samples at the same time.

The invention belongs to tobacco field, especially relating to a method for measuring phthalic acid ester (PAE) in water-based adhesive for tobacco. The method comprises the following steps: extracting phthalic acid ester (PAE) in water-based adhesive for tobacco by acetone, measuring by gas chromatography, using HP-5 or an equivalent chromatographic column, using a flame ionization detector (FID) and taking benzyl benzoate as an internal standard substance. The method for measuring phthalic acid ester (PAE) in water-based adhesive for tobacco provided by the invention is accurate in measurement, simple in operation, high in sensitivity and good in repeatability, which is applicable to carrying out qualitative and quantitative measurement on phthalic acid ester (PAE) in water-based adhesive for tobacco for technicists in enterprises of tobacco field and tobacco bonding adhesive and fills up the technical gap in the field.

A synthetic method of a general artificial antigen of phthalate plasticizers for immunodetection belongs to the field of bio-chemical engineering technology. The synthetic method of the present invention comprises the following steps of carrying out an esterification reaction between phthalic acid and 6-(fluorenyl methoxy carbonyl acyl-amino)-1-hexanol, removing fluorene methoxy carbonyl acyl protecting groups to form a hapten, and coupling with amino from carrier protein to obtain the general artificial antigen of phthalate plasticizers. Experimental results disclose that titer of antiserum obtained by immunizing animals by the antigen of the invention is up to 160000;the 50% inhibiting concentration IC50 for DBP, DEHP and DINP is less than 500 ng / ml; and the generated antibodies have good generality and high sensitivity. The antigen or antibodies of the invention can be used for the establishment of enzyme-linked immunosorbent assay and colloidal gold test paper rapid detection methods, thus can be used for rapid detection of residues of phthalic acid ester plasticizers in food, and have broad application prospects.

The invention discloses a resin anti-corrosive paint which is prepared from 10-35 of resin composition, 5-15 of plasticiser, 45-70 of solvent, and 1-5 of assistant according to the weight percent, wherein the resin composition is prepared from 30-60 of polyvinyl chloride, 20-50 of chlorinated polyvinyl chloride and 0-20 of polyfluortetraethylene according to the weight percent; the plasticiser is phthalic acid esters; the solvent is one or more of a ketone solvent, a benzene solvent or an ester solvent; the assistant is antioxidant or age inhibitor; and the polyvinyl chloride uses powder as the raw material. The anti-corrosive paint has the advantages of corrosion resistance, long service life, simple and convenient coating and mending, little pollution and cheap price, can be widely used for flue gas purification and surface corrosion of chemical equipment, engineering construction, ships, and the like, and has a good market prospect.

The invention relates to the following general formula compound (I) and use of the general formula compound in preparing anti-inflammatory and anti-endotoxin medicines. In formula I, R is an acid solubilizing side chain of hydroxide radical in an arctigenin molecule, and can be an acid group or side chain imported through alkylation reaction or acylating reaction, such as sulphonic acid ester, sulfuric acid ester, organic phosphate, succinate, propionic ether, butyric ester, semi-succinate, semi-glutaric acid ester, semi-tartrate, semi-phthalic acid ester, m-benzene sulfonic acid ester and so on.

The invention discloses a method for measuring the phthalate ester content of tipping paper for tobaccos. The method comprises the steps of: preparation of internal standard extract liquor, standard working solution and sample solution, gas chromatography-mass spectrography, calculation of measurement results and the like. The improved and optimized measurement method has the advantages of operation simplicity and accuracy, high sensitivity, high recovery rate, high repeatability and the like. Errors caused by pretreatment or apparatus precision and the like are effectively reduced by utilizing an internal standard quantity. Under adopted chromatographic conditions, seven target compounds and internal standard chromatographic peaks have relatively higher degrees of separation, relatively higher linear correlation and the detection limit of 0.01 to 0.03 mu g per centimeter spare. By the method, a standard recovery rate is 94 to 106 percent and an average relative standard deviation is 3.4 to 4.8.

The present invention discloses a flame-retardant cation dyeable polyester copolymer and the preparation method. The method includes esterification and condensation reactions and the reactions take terephthalic acid and ethylene alcohol as a first monomer and a second monomer, and reactive phosphorus flame retardant and m-phthalic acid ester with sulphonate respectively as a third monomer and a fourth monomer; metatitanic acid ester is catalyst, phosphorus compound is stabilizer and alkali metal compound is assistant additive. The fiber of the product provided by the present invention with excellent flame retardant and cation dyeability can ensure good processing ability and dynamic performance and apply the polyester to different spinning processes.

The invention relates to immobilized microspheres for degrading bacteria of PAEs (phthalic acid esters) in farmland soil and a preparation method of such immobilized microspheres. The preparation method includes (1), preparing a bacterial suspension, namely culturing pseudomonas putida RXX-01 (preservation number: CGMCC No.13224) to a logarithmic phase, cleaning bacteria with normal saline, and mixing the bacteria into the bacterial suspension with the normal saline so as to enable OD600 of the bacterial suspension to equal 0.8-1.2; (2), preparing mixed bacterial liquid, namely preparing a sodium alginate solution with sterile water, adding activated carbon into the sodium alginate solution with mixing uniformly to obtain mixed liquid, and adding the bacterial suspension obtained in the step (1) into the mixed liquid with mixing uniformly so as to obtain the mixed bacterial liquid, wherein the mixed bacterial liquid comprises, by weight, 15-25% of bacterial suspension, 2-3% of sodium alginate and 2-4% of activated carbon; (3) preparing the immobilized microspheres, namely preparing a 20-30 g / L calcium chloride solution with sterile water, dropwise adding the mixed bacterial liquid into the calcium chloride solution, and crosslinking for 20-30 hours so as to obtain the immobilized microspheres, wherein a volume ratio of the mixed bacterial liquid to the calcium chloride solution is 1:1.5-1:2. The preparation method is simple, and the immobilized microspheres are high in efficiency of degrading the phthalic acid esters in the soil.

The invention belongs to the field of power materials and in particular discloses anticorrosive paint for power cables. The paint is prepared from crylic acid, N-methyl pyrrolidone, laurinol polyoxyethylene ether, silicone emulsion, phthalic acid ester, borax, sodium silicate, white graphite, tripolyphosphoric acid, nanosize silica powder and nano titanium dioxide. The paint is capable of effectively preventing acid-base salts from corroding power cables and is relatively good in high-temperature flame retardancy and mechanical property.

The invention discloses a hydrophilic magnetic resin with a high specific surface area and a preparation method thereof and a method for rapidly extracting phthalic acid ester in a water body, belonging to the technical filed of preparation of absorbent resins for rapid enrichment and separation of trace organic substances in the water body. A precursor resin is prepared through addition of magnetic particles and the copolymerization reaction of divinylbenzene, benzoic acid vinyl esters and glycidyl methacrylate, the specific surface area of the resin is improved by a post cross-linking reaction, an ester group on the surface of the resin is hydrolyzed in an alkaline solution, so that the magnetic resin rich in hydroxyl perssad with high specific surface area is prepared. The resin has higher extracting performance and selectivity to phthalic acid ester substances in the water body, and trace phthalic acid ester substances in large volume of water body can be rapidly and efficiently enriched and separated through a rapid separation technology based on a novel magnetic solid phase extraction rod.

The invention discloses a water-based superspeed cigarette lap adhesive and a preparation method thereof. In the product, ethylene-vinyl acetate copolymer emulsion and polyvinyl alcohol are used as main raw materials; under the action of tert-butyl hydroperoxide-ferrous sulfate, a part of residual vinylacetate is reacted; then the content of the vinylacetate is controlled to be less than 1,000mg / kg by vacuum pumping; the viscosity of an adhesive and the solid content technical index are adjusted by adding lemon butyl acetate plasticizer and water; and the lap adhesive is lacte fluid and has fine and smooth texture, the particles are uniform, the viscosity is 200 to 1,000mPa.S, the solid content is 45 to 55 percent, the pH value is 4 to 6, the content of vinyl acetate is less than 1,000mg / kg, phthalic acid esters are less than 500mg / kg, and the formaldehyde content is less than 50mg / kg. The product is the water-based, safe and environment-friendly, is high in drying speed, and used for lapping and bonding cigarette paper of a superspeed cigarette making machine of a cigarette making factory, and has strong bonding capacity; and the engine speed reaches 12,000 to 17,000 cigarettes / min.

The invention discloses a bacillus strain capable of efficiently degrading DMP (dimethyl phthalate), a culture method and application thereof to remediation of soil PAEs (phthalic acid esters) pollution. A strain QD-9-10 which grows by mainly taking DMP as a carbon source is separated and identified from black soil covered with mulching films for a long term by adopting inorganic salt culture medium. According to morphological characteristic observation of a colony and 16SrDNA base sequence determination and homological analysis, the identification result of the bacterium is that QD-9-10 belongs to Bacillus subtilis. According to results of orthogonal experiments, the optimum culture method of the strain QD-9-10 is to perform culture by adopt inorganic salt culture medium under culture conditions that pH is 8.0, temperature is 35DEG C and shaking speed is 150rpm and DMP initial concentration is 100mg L<-1>, and biomass reaches the maximum at 32h. In addition, according to substrate utilization tests, the strain QD-9-10 can also utilize other common PAEs. Accordingly, the Bacillus subtilis QD-9-10 strain has a capability of degrading DMP and other common PAEs, and has a certain application prospect in aspects of degrading PAEs pollutants and remedying soil PAEs pollution.

A method for quickly detecting phthalic acid esters compound in plastics, comprising: producing a standard sample; performing the infrared spectrum transmission test; obtaining the linear regression equation and correlation coefficient and detecting the plastics. The method uses the di(2-ethy(hexylphthalate)-DEHP as main researching object and the standard sampler is prepared by adding DEHP in the blank solution thereby preventing the change of character substance DEHP due to effect of adding additive and high temperature during expanding a roller, thus the reliability of the standard curve is ensured and the effect of the solvent is not easy to be detected using the infrared spectrum; The curve of peak area ratio of carbonyl peak to carbon-hydrogen telescopic vibration to the concentration is calculated using relative peak area and the effects of the exogenous pollution and other factors are reduced and more reasonably the reliability of the standard curve and the result reality are ensured; the sampler processing way is simple and the infrared spectrum transmission test is performed on by dissolving the plastics to be tested, in favor of lab quick detection.

The invention provides an environment-friendly anti-bacterial PVC (Polyvinyl Chloride) thin film. The environment-friendly anti-bacterial PVC thin film is prepared from the following raw materials in parts by weight: 90-110 parts of PVC resin powder, 0.1-0.2 part of lavender essential oil, 20-25 parts of acetyl-tri-n-butyl citrate, 4-8 parts of heat stabilizer and 0.2-0.6 part of lubricant, wherein the heat stabilizer is one or more than one of calcium ricinoleate, calcium stearate, zinc stearate or magnesium stearate, and the lubricant is one or more than one of glyceryl stearate, octadecanamide, paraffin wax and polyethylene wax. The environment-friendly anti-bacterial PVC thin film can be used for inhibiting the breeding of bacteria around the thin film. Compared with a common commercially available thin film, the environment-friendly anti-bacterial PVC thin film has an obvious inhibitory effect on trichoderma viride, escherichia coli and staphylococcus aureus. As the lavender essential oil is a natural plant extraction anti-bacterial agent, the environment-friendly anti-bacterial PVC thin film can be used for a long term and is safe and non-toxic. The acetyl-tri-n-butyl citrate and tri-n-butyl citrate are used as the plasticizers, so that the health problem caused by use of phthalic acid ester-containing plasticizer products can be effectively avoided.

The invention relates to a new composition by slowing-releasing envelope with cysteamine or its saline compound. Said composition comprises: A, cysteamine or its saline compound in 1-95 wt %; main materials used for covering in 1-80 wt % which is mainly sodium alginate, polyacrylic resin II, polylactic acid, polyamino acid, corn zein plasm, poly(D.L-Lactide)-poly(ethylene glycol) block copolymer, crosslinked polyvinyl pyrrolidone, hydroxypropylmethylcellulose phtha late, polyvinyl acetate phthalic acid esters, cellulose ethyl ether, and succinic acetate methylcellulose. This invention also relates to process of slowing-releasing envelope on new compound with cysteamine or its saline, and its use as animal feedstuff additive. The strongpoint of said invention is the excellent effect on envelope; the available utilization by animals of envelope materials degraded in the inner body of animals; further, the reached slowing-releasing technique on the combined use of envelope materials which can express the biological value more effectively in inner body of animals.

The invention discloses a sound-insulation elastic plastic floor. The floor comprises a surface layer, an interface layer and a base layer, wherein the surface layer comprises, by weight, 80-90 parts of a polyvinyl chloride resin, 100-120 parts of calcium carbonate, 15-25 parts of dioctyl phthalate, 10-15 parts of a zinc-barium composite stabilizer, 1-5 parts of an epoxy resin, 1-5 parts of pentaerythritol and 0.5-2 parts of trioctyl ester; the interface layer comprises, by weight, 100-120 parts of the polyvinyl chloride resin, 20-30 parts of calcium carbonate, 50-60 parts of dioctyl phthalate, 0.5-3 parts of pentaerythritol, 0.5-2 parts of the trioctyl ester and 0.5-2 parts of an AC foaming agent; and the base layer comprises, by weight, 90-120 parts of the polyvinyl chloride resin, 60-70 parts of dioctyl phthalate, 3-8 parts of barium stearate, 2-6 parts of pentaerythritol, 1-3 parts of the trioctyl ester and 3-8 parts of acetyl citrate.

The invention provides a pesticide aqueous emulsion and a preparation method thereof. The pesticide aqueous emulsion has effective constituents of abamectin and chlorantraniliprole amide and also comprises a solvent and a surface active agent, wherein the solvent is selected from one or more substances of N-alkyl pyrrolidone, alkylene carbonic ester, phthalic acid ester, ionic liquid and arene; the surface active agent is selected from one or more substances of an anion surface active agent and a nonionic surface active agent. The preparation method comprises the following steps: (1) preparing a disperse phase; (2) preparing a continuous phase; and (3) mixing the disperse phase and the continuous phase under high shear to prepare the pesticide aqueous emulsion. The pesticide aqueous emulsion has the advantages of stability, high efficiency, low toxicity, environmental protection, no ignition hazard, convenient storage and transportation, and the like.

The invention discloses an enteric-coated tilmicosin sustained release microcapsule and a preparation method thereof, and belongs to the field of tilmicosin preparations. The enteric-coated tilmicosin sustained release microcapsule is prepared from 10wt%-50wt% of raw tilmicosin powder, 40wt%-88wt% of an auxiliary fatty powder material and 2wt%-10wt% of an enteric coating material, wherein the enteric coating material is prepared from one or more of cellulose acetate phthalate, hydroxypropyl methylcellulose phthalate, L-type acrylic resin, S-type acrylic resin, polyvinyl acetate phthalate and hydroxypropyl methylcellulose acetate succinate; the diameter of the prepared microcapsule is 50-200 mu m. The preparation method comprises the steps as follows: the raw tilmicosin powder and the auxiliary material are subjected to primary coating, are subjected to secondary coating with the enteric coating material and then are dried, and a finished product is obtained. According to the enteric-coated tilmicosin sustained release microcapsule and the preparation method thereof, the sustained release purpose is achieved, the acting time of tilmicosin is prolonged, the fluidity and the dispersity of a drug are improved, the pharmacodynamical function is remarkably improved, and the dosage of the drug is reduced.