311 results about "Pentanoic Acids" patented technology

The invention relates to a method for producing volatile fatty acid through promoting the anaerobic fermentation of kitchen wastes. The method comprises the steps of firstly, crushing the kitchen wastes to be up to the particle size of 1-5mm; then, regulating the content of solids to 100mg/L; next, placing the crushed kitchen wastes into an anaerobic fermentation reactor, adding 10-40g/L of marketing zero-valent iron with the particle size of 800 meshes, fermenting at the temperature of 15-40 DEG C for 4-17 days while stirring at the rotating speed of 120r/min, centrifuging, recycling the zero-valent iron in filter residues, and taking out the residual organic components to be composted or used as a liquid fertilizer to obtain the volatile fatty acid with the yield of 29.1-35.8g/L in a supernatant liquid, wherein the volatile fatty acid is detected to contain 32% of acetic acid, 17% of propionic acid, 27% of n-butanoic acid and 20% of n-pentanoic acid when the yield of the volatile fatty acid in the supernatant liquid is 29.1g/L. Compared with the conventional anaerobic fermentation for the kitchen wastes, the method has the advantages that the content of the volatile fatty acid in the supernatant liquid is increased by 2.3-13 times, the recycling of the kitchen wastes is effectively realized, and the method is low in cost, high in speed and high in social, economic and environmental benefits.

The invention relates to a medicament for fast preventing the malignant float grasses and the water algae and the application thereof, belonging to the pesticide formulation technical field, which is characterized in that the medicament comprises from 40% to 90% of a plant vinegar fluid, from 5% to 35% of an organic acid, and from 1% to 20% of pesticide addition agent, the plant vinegar fluid is either a bamboo vinegar fluid, a wooden vinegar fluid, and (or) grass vinegar fluid, the organic acid is one of or a mixture of more than one of a formic acid, an acetic acid, a propionic acid, a 2-methyl propionic acid, an ethyl acetic acid, a 4-hydroxy ethyl acetic acid, a pentanoic acid, a benzoic acid, a 2,6-hydroxy benzoic acid, a 3-hydroxy-4-methoxy benzoic acid or a 3-methoxy-4-hydroxy benzoic acid. The medicament has the advantages of fast destroying the chlorophyll, stopping the plant to do the photosynthesis, commonly killing the water algae in a half hour and the float grass in three hours by spraying, having low production cost, strong killing capability, wide adaptable temperature range and pH value range. The active component of the invention has the advantages of being the natural-occurring substance, no corrosion, nonirritant, safe use, and reliability, easy biodegradation, and no secondary pollution.

The invention relates to isoalantolactone derivatives and salts thereof and provides an isoalantolactone derivative as shown in a formula (I). Salification acids are selected from inorganic acids or organic acids; the inorganic acids are selected from hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boric acid, seleninic acid, phosphomolybdic acid, phosphorous acid and sulphurous acid; the organic acids are selected from citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-acid, oxalic acid, methylsulfonic acid, pentanoic acid, oleic acid, lauric acid, p-toluene sulfonic acid, 1-naphthalenesulfonic acid, 2-naphthalenesulfonic acid, phthalic acid, tartaric acid, malonic acid, succinic acid, fumaric acid, glycolic acid, mercaptan acid, glycine, sarcosine, sulfonic acid, nicotinic acid, methylpyridine acid, isonicotinic acid, benzoic acid or substituted benzoic acid.

Disclosed is a method for synthesizing d-biotin by catalytic double debenzylation. The method is simple in process, high in yield and low in cost. The method includes: dissolving (3aS, 6aR)-hexahydro-2-oxo-1, 3-dibenzyl-1Hthieno [3, 4-d] imidazole-4-pentenoic acid into low molecular alcohol, adding mixed catalyst of Palladium-carbon and solid superacid, and feeding hydrogen for stirring reaction for 2-12 hours at 80-200 DEG C and 2.5-12.5 MPa; filtering after reaction, and washing residue with 1-20% (weight ratio) aqueous alkali; filtering, adjusting pH of filtrate to acidity, and standing for crystallization; and filtering to obtain the crystallized d-biotin. The method is applicable to production of the d-biotin.

The invention relates to an application of an isoalantolactone derivative and a salt thereof in the preparation of medicines for treating lung fibration, and provides an isoalantolactone derivative represented by formula (I). An acid for forming the salt is an inorganic acid or an organic acid, the inorganic acid is selected from hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boric acid, seleninic acid, phosphomolybdic acid, phosphorous acid and sulfurous acid, and the organic acid is selected from citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-lactic acid, oxalic acid, methanesulfonic acid, pentanoic acid, oleic acid, lauric acid, p-methyl benzenesulfonic acid, 1-naphthalenesulfonic acid, 2-naphthalenesulfonic acid, phthalic acid, tartaric acid, propane diacid, succinic acid, fumaric acid, glycollic acid, thioglycollic acid, glycine, sarcosine, sulfonic acid, nicotinic acid, methylpyridine acid, isonicotinic acid, benzoic acid and substituted benzoic acid.

The invention relates to a preparation method of (3R, 5R)-3,5-dihydroxy-6-methyl cyan-caproate (I) and belongs to the technical field of pharmaceutical chemistry. The preparation method concretely comprises the following steps of: firstly, carrying out asymmetric catalysis alcoholysis on 3-siloxy cyclopentane anhydride (II) to prepare (R)-3-siloxy-5-alkoxy-5-oxo-pentanoate (III); secondly, condensing the (R)-3-siloxy-5-alkoxy-5-oxo-pentanoate (III) and methyl cyanoacetate to prepare (R)-2-cyano-3-oxo-5-siloxy diethyl pimelate (IV); thirdly, carrying out decarboxylation on the (R)-2-cyano-3-oxo-5-siloxy diethyl pimelate (IV) to prepare (R)-3-hydroxy-5-oxo-6-benzyl cyanohexanoate (V) by using desilicication protective groups; and fourthly, carrying out asymmetric reduction on the (R)-3-hydroxy-5-oxo-6-benzyl cyanohexanoate to prepare a product of (3R,5R)-3,5-dihydroxy-6-methyl cyan-caproate (I). The preparation method is mild in reaction conditions, simple and convenient to operate, high in stereoselectivity, environment-friendly, and suitable for industrial production; and products have high yield, the used chiral catalyst is small in dosage and can be recovered with fix quantify, raw materials which are easily obtained are low in cost, and particularly hypertoxic cyanides are avoided.

The invention discloses a new method for preparing ceftizoxime alapivoxil hydrochloride and belongs to the technical field of medicine synthesis. The method comprises the following steps: step (1), performing Boc protection on 7-amino of raw material 7-amino-3-cephem-4-carboxylic acid (7-ANCA) and then making the raw material have reaction with iodomethyl pivalate, then removing Boc protection group to obtain a midbody 7-amino-3-cephem-4-carboxylic pivaloyl oxymethyl ester (7-ANCA-POM); step (2), making N-t-butyloxycarboryl-L-alanine (Boc-L-Ala) and methoxyiminoacetic acid (ATMA) have condensation reaction to obtain a midbody 2-(2-N-t-butyloxycarboryl-amino-(S)-triacylamino-thiazole-4-yl)-2-(Z)-methoxyimino-acetic acid (Boc-L-Ala-ATMA); step (3), activating the midbody Boc-L-Ala-ATMA and making the midbody Boc-L-Ala-ATMA have condensation reaction with the midbody 7-ANCA-POM, and then removing the Boc protection group to prepare a target compound ceftizoxime alapivoxil hydrochloride (CZX-AP-HC1,I). The method adopts a collection type synthesis route, is simple and convenient to operate and mild in technical conditions, has high product quality and low cost, and avoids the problem about benzothiazole residue caused by the use of AE active ester in the present technique, so the collection type synthesis route is a good synthesis route suitable for industrial production.

The invention relates to a cefcapene pivoxil hydrochloride and a method for preparing an intermediate of cefcapene pivoxil hydrochloride, the method is characterized in that 7-DACA (iii) is taken as a raw material, and is performed condensation reaction with cefcapene pivoxil hydrochloride side chain acid (iv) and a carbamylated reagent to obtain tertbutyloxycarbonyl cefcapene acid sodium salt (vi), an amino protective group is removed to obtain the cephalospene acid (ii), then performed esterification reaction with iodomethyl pivalate, salifying with hydrochloric acid to obtain the cefcapene pivoxil hydrochloride hydrate (i) (a flow chart is shown as follows). The preparation method has the advantages of cheap raw material, easy raw material acquisition, less reaction step, high yield and high purity of intermediate and product, and is suitable for industrial production.

A PE corrugated pipe modified with phyllosilicate is characterized by being prepared by weight part from high-density polyethylene, low-density polyethylene, inorganic montmorillonoid, 1-butyl-3-methylimidazolium hexafluorophosphate, an ethanol aqueous solution with the concentration of 40-60%, butanediamine, vinyl cyanide, raney nickel, alpha-(diphenylphosphino) acetic acid, borax, vinyltrimethoxyacyloxygroupsilanes, gamma-glycidyl trimethoxy silane, N,N-diphenyl p-aniline, tert-butyl peroxypivalate, cobalt stearate, polyvinyl chloride, glass fibers, decabromodiphenyl ether, antimonous oxide and dibasic lead phthalate. The PE corrugated pipe has the advantages of being high in crushing resistance, good in corrosion resistance, antistatic, flame-retardant and long in service life.

The invention relates to a preparation method of Cefditoren Pivoxil. The preparation method comprises steps as follows: 7-ACA (3-acetyloxymethyl-5-thio-7-amino-8-oxy-1-nitrogen heterobicyclic octyl-2-ene-2 carboxylic acid) is taken as a starting raw material and is subjected to iodination and Wittig reaction after silanization protection, and a Cefditoren parent nucleus 7-ATCA (7-amino-3-[(Z)-2-(4-methyl-5-thiazole) vinyl]-3-cephem-4-carboxylic acid) is generated; after amino protection of aminothiazole ethyl gallate, a compound 2 is produced from 7-ATCA under catalysis of AlMe3; the compound2 is subjected to an esterification reaction with iodomethyl pivalate under actions of a phase transfer catalyst and an acid adsorbent, the amino protection is removed, and a target product CefditorenPivoxil is obtained. According to the preparation method, reaction conditions are mild, product purity and yield are high, the process is stable, amplification is easy, and the method is applicable to industrial production.