The invention provides a pregnant sow high-efficiency feed and a preparation method thereof. Raw materials such as corn, maize, wheat bran, soybean, fish meal, feather meal, soybean phospholipids, powdered zeolite, L-lysine hydrochloride, DL-methionine, threonine, arginine, talc powder, calcium hydrogen phosphate, potassium chloride, sodium bicarbonate, sodium chloride, coating VC (vitamin C), monomer VE (vitamin E), vitamin premix, choline, a trace element premix, ethoxy quinoline, a physiological regulator, a hydrated aluminosilicate mycotoxin adsorbent and the like are adopted, and the pregnant sow high-efficiency feed is prepared by smashing and mixing the raw materials. The feed has the following advantages: especially the equilibrium of amino acid, a special function of the arginineto a pregnant sow, the nutrition effect of fiber source and level to the pregnant sow, the nutrition effect of energy source and level to the pregnant sow and the nutrition requirement difference of different parities are especially considered, so that the breeding potential of the pregnant sow can be greatly excavated, the survival rate of embryos is improved, nutrition requirements in each stage of good development of the embryos are guaranteed, and the normal physique and body weight increase of the sow in pregnancy duration are maintained.