The invention relates to a
controlled degradation magnesium alloy coating stent and a preparation method. The
stent body is made of medical high purity
magnesium or
magnesium alloy by mechanical
processing or
laser carving; the
stent body is provided with a
drug-loading
coating which bears curative
drug; the surface of the stent body is provided with an anti-corrosive
coating; the surface of the anti-corrosive coating is provided with a degradable
polymer film
drug-loading coating; the preparation method includes
surface cleaning, preparation of the degradable
polymer film drug-loading coating, and application of curative drug; through (1)
surface cleaning, (2)preparation of the degradable
polymer film drug-loading coating, and (3)application of curative drug, an
oxide film is formed on the surface; different drugs and dosage can be fixed by regulating the molecular weight and the thickness of the polymer layer, the drug-loading quantity is more than 30 percent, which improves the fixed stability of the drug, greatly reduces the degradation speed of the
magnesium alloy and controls release of the drug, delays
corrosion of the
magnesium alloy, extends the service life of the stent, is safe in use, and meets the clinical requirement.