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Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction. The visual display also includes windows depicting a virtual fly-through perspective and real-time video images acquired at the head of the endoscope, which can be stored as data, with an audio or textual account.

A method and apparatus for communicating with and monitoring the operation of a device implanted within a patient. A transceiver capable of being implanted within a patient provides a communication interface between an implanted medical device and a monitor external to the patient's body. The external monitor can communicate with a remote monitoring center over a communication network. The external monitor also provides control signals to the implanted device via the transceiver unit. The transceiver apparatus is capable of two-way communication between the implanted device and the external monitor. The transceiver apparatus is also capable of detecting actions performed by the implanted device and physiological signals directly from the patient's body. Thus, the transceiver apparatus provides circuitry for determining whether an implanted medical device is operating properly. The transceiver apparatus provides a way to remotely reprogram one or more implanted medical devices.

Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and / or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important application of the invention involves a method and device for monitoring blood glucose values.

A virtualization infrastructure that allows multiple guest partitions to run within a host hardware partition. The host system is divided into distinct logical or virtual partitions and special infrastructure partitions are implemented to control resource management and to control physical I / O device drivers that are, in turn, used by operating systems in other distinct logical or virtual guest partitions. Host hardware resource management runs as a tracking application in a resource management “ultravisor” partition, while host resource management decisions are performed in a higher level command partition based on policies maintained in a separate operations partition. The conventional hypervisor is reduced to a context switching and containment element (monitor) for the respective partitions, while the system resource management functionality is implemented in the ultravisor partition. The ultravisor partition maintains the master in-memory database of the hardware resource allocations and serves a command channel to accept transactional requests for assignment of resources to partitions. It also provides individual read-only views of individual partitions to the associated partition monitors. Host hardware I / O management is implemented in special redundant I / O partitions. Operating systems in other logical or virtual partitions communicate with the I / O partitions via memory channels established by the ultravisor partition. The guest operating systems in the respective logical or virtual partitions are modified to access monitors that implement a system call interface through which the ultravisor, I / O, and any other special infrastructure partitions may initiate communications with each other and with the respective guest partitions. The guest operating systems are modified so that they do not attempt to use the “broken” instructions in the x86 system that complete virtualization systems must resolve by inserting traps. System resources are separated into zones that are managed by a separate partition containing resource management policies that may be implemented across nodes to implement a virtual data center.

Apparatus and methods are disclosed for detecting anomalies in microwave penetrable material that may be used for locating plastic mines or pipes underneath the ground. A transmitter is positioned at a plurality of different positions above the ground. A microwave signal is transmitted that is stepped over a plurality of frequencies. At each position, a plurality of reflections are received corresponding to each of the plurality of frequencies that were transmitted. A complex target vector may be produced at each position that contains complex values corresponding to magnitude, phase, and time delay for each of the plurality of reflections received at that location. A complex reference data vector may be produced, either based on predetermined values or based on data from the received plurality of reflections. A comparison is made between the complex target vector and the complex reference data vector to produce a channel vector. In one embodiment, an operator may be applied to the channel vector such as a complex filter matrix or to add a complex conjugate. A response signal is produced and anomalies are detected by variations in the response signal with respect to the plurality of positions.

Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction. The visual display also includes windows depicting a virtual fly-through perspective and real-time video images acquired at the head of the endoscope, which can be stored as data, with an audio or textual account.

A virtualization infrastructure that allows multiple guest partitions to run within a host hardware partition. The host system is divided into distinct logical or virtual partitions and special infrastructure partitions are implemented to control resource management and to control physical I / O device drivers that are, in turn, used by operating systems in other distinct logical or virtual guest partitions. Host hardware resource management runs as a tracking application in a resource management “ultravisor” partition, while host resource management decisions are performed in a higher level command partition based on policies maintained in a separate operations partition. The conventional hypervisor is reduced to a context switching and containment element (monitor) for the respective partitions, while the system resource management functionality is implemented in the ultravisor partition. The ultravisor partition maintains the master in-memory database of the hardware resource allocations and serves a command channel to accept transactional requests for assignment of resources to partitions. It also provides individual read-only views of individual partitions to the associated partition monitors. Host hardware I / O management is implemented in special redundant I / O partitions. Operating systems in other logical or virtual partitions communicate with the I / O partitions via memory channels established by the ultravisor partition. The guest operating systems in the respective logical or virtual partitions are modified to access monitors that implement a system call interface through which the ultravisor, I / O, and any other special infrastructure partitions may initiate communications with each other and with the respective guest partitions. The guest operating systems are modified so that they do not attempt to use the “broken” instructions in the x86 system that complete virtualization systems must resolve by inserting traps.

A system for monitoring a patient's vital signs that features a vital-sign monitor including sensors for measuring from the patient at least one of the following vital-sign data: O2 saturation, blood pressure, electro-cardiogram, respirator rate, and blood glucose level. The system also includes a global positioning system that determines location-based data. A wireless transmitter, in electrical contact with the vital-sign monitor and global positioning system, receives the vital-sign and location-based data and wirelessly transmits these data through a conventional wireless network. A gateway software piece receives and processes the data from the wireless network and stores these data in a computer memory associated with a database software piece. The system also includes an Internet-based user interface that displays the vital sign data for both individual patients and care-providers.

The invention relates to a semiconductor device including a plurality of thin film transistors provided on a base member having a curved surface. The surface may be bent in either a convex shape or a concave shape. All channel length directions of the plurality of thin film transistors may also be aligned in the same direction. Further, the channel length direction may be different from the direction in which the base member is bent. A pixel portion and a driver circuit portion may also be provided on the base member. The invention also includes a method of manufacturing a semiconductor device including forming a layer to be peeled including an element of a substrate, bonding a support member to the layer to be peeled, and bonding a transfer body to the layer to be peeled.

A medical probe device comprises a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and a stylet guide for directing a flexible stylet outward through the stylet port and through intervening tissue at a preselected, adjustable angle to a target tissue. The total catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radiofrequency electrode. Preferably, the non-conductive layer is a sleeve which is axially moveable on the electrical conductor to expose a selected portion of the electrical conductor surface in the target tissue. The stylet can also be a microwave antenna. The stylet can also be a hollow tube for delivering treatment fluid to the target tissue. It can also include a fiber optic cable for laser treatment. The catheter can include one or more inflatable balloons located adjacent to the stylet port for anchoring the catheter or dilation. Ultrasound transponders and temperature sensors can be attached to the probe end and / or stylet. The stylet guide can define a stylet path from an axial orientation in the catheter through a curved portion to a lateral orientation at the stylet port.

The ability to combine multiple audio signals captured from the microphones in a microphone array is frequently used in beamforming systems. Typically, beamforming involves processing the output audio signals of the microphone array in such a way as to make the microphone array act as a highly directional microphone. In other words, beamforming provides a “listening beam” which points to a particular sound source while often filtering out other sounds. A “generic beamformer,” as described herein automatically designs a set of beams (i.e., beamforming) that cover a desired angular space range within a prescribed search area. Beam design is a function of microphone geometry and operational characteristics, and also of noise models of the environment around the microphone array. One advantage of the generic beamformer is that it is applicable to any microphone array geometry and microphone type.

Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and / or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important application of the invention involves a method and device for monitoring blood glucose values.