220 results about "Ftir spectra" patented technology

The system and method for spectral analysis uses a set of spectral data. The spectral data is arranged according to a second dimension, such as time, temperature, position, or other condition. The arranged spectral data is used in a signal separation process, such as an independent component analysis (ICA), which generates independent signals. The independent signals are then used for identifying or quantifying a target component.

A spectral measurement device comprising an entrance aperture for receiving an electromagnetic energy and a mask located at the entrance aperture in the form of a two-dimensional encodement pattern. An optical element conditions the electromagnetic energy received from the mask for presentation to the spectral dispersion element and the and a spectral dispersion element disperses the electromagnetic energy in one or more dimensions. Additionally, the optical element conditions the dispersed electromagnetic energy onto an array of detector elements.

An illumination subsystem for use in optical analysis which provides spatially and angularly homogenized radiation to the sample being analyzed. The system eliminates the illumination system as an interferent in the overall optical analysis. Thus, modest translations or rotations of the illumination source or changing the illumination source does not require recalibration of the instrument or prior modeling of illumination variability due to such changes. Illumination stability is achieved by incorporating a light pipe which both angularly and spatially homogenizes the light. Further, a series of filters and / or lenses are incorporated to provide bandpass filtering which eliminates unwanted wavelengths or bands of wavelengths from contacting the tissue and allows for a higher signal-to-noise ratio when the sample is tissue, while preventing thermal damage.

Novel spectrometer arrangements are described. They may employ a resin-based preconcentration system to sample chemical vapors. A field-widened interferometer modulates radiant energy. The signal generated by the interaction of the radiant energy with the sample is detected and processed by a computer. A variety of enhancements to the basic design are described, providing a family of related spectrometer designs. These spectrometers have applications in spectrometry, spectral imaging and metrology.

An apparatus for spectrometry that includes a spectrometer configured for second order focusing and capable of 2π azimuthal collection.

Spectroscopic devices and techniques for determining the presence or absence of an analyte of interest or the presence or absence of desired characteristics of an object are provided. In an embodiment, a portable device or attachment for a smart phone or comparable device includes a light source and a detector. The detector detects light after reflection from a target surface and, based upon attributes in the detected light absent from the emitted light such as covariances among different wavelengths, determines the presence or absence of the analyte of interest.

Fiber-laser light is Raman shifted to eye-safer wavelengths prior to spectral beam combination, enabling a high-power, eye-safer wavelength directed-energy (DE) system. The output of Ytterbium fiber lasers is not used directly for spectral beam combining. Rather, the power from the Yb fiber lasers is Raman-shifted to longer wavelengths, and these wavelengths are then spectrally beam combined. Raman shifting is most readily accomplished with a “cascaded Raman converter,” in which a series of nested fiber cavities is formed using fiber Bragg gratings.

Systems and methods for spectral imaging are disclosed. Such spectral imaging can be used to determine properties of a subject material at different locations upon the surface and / or within the material. For example, strain and / or stress within an imaged area of the material can be determined. A system for spectral imaging can include a light source, a two-dimensional sensor array configured to image light from a two-dimensional area of a subject material, a filter configured to filter light from the subject material before the light is imaged and a processor in communication with the two-dimensional sensor array. The processor can be configured to determine a property of the subject material at a plurality of locations within the two-dimensional area of the subject material. Such spectral imaging systems can facilitate the performance of piezospectroscopic measurements of two-dimensional surfaces in a rapid manner while preserving accuracy.

An optical tomography system has a group of lasers for generating light of multiple distinct wavelengths within a first wavelength band. Light from these lasers is directed into mammalian tissue at laser-specific locations on the tissue, and light from the mammalian tissue is collected at a plurality of reception points. Collected light from each reception point is separated according to its wavelength, and received by a photodetector to produce path attenuation signals representing attenuation along paths between the laser-specific locations on the tissue and the reception points. Image construction apparatus generates a tomographic image of heme concentrations in the mammalian tissue from the path attenuation signals. In an alternative embodiment, there is a second group of lasers operating in a second wavelength band, and the image construction apparatus can generate an image of heme oxygenation In the mammalian tissue.

There is disclosed a device or apparatus that is particularly suitable for use in the analytical fields of polarized light microscopy and spectroscopy / spectral imaging. The apparatus comprises an automated polarized light microscope combined with means for achieving spectroscopic analysis. The apparatus may optionally include means for spectral imaging associated with the means for achieving spectroscopic analysis. Any means for achieving spectroscopic analysis may be utilized for example Raman, mid-infrared, near-infrared, ultraviolet, visible, luminescence, and the like.

A method and apparatus are provided for correcting gamma ray data representative of gamma ray energies for spectral degradation. The method and apparatus include degrading reference gamma ray spectra. At least one correction factor is calculated between the degraded gamma ray spectra and the reference gamma ray spectra. The gamma ray data are then corrected using a calculated correction factor. Another method is provided for determining a correction factor for correcting data representative of gamma ray energies for spectral degradation. The method includes disposing a downhole tool in a simulated environment representative of actual downhole conditions, the tool including a neutron source and at least one gamma ray detector. The temperature of at least one of the gamma ray detectors of the tool is then varied while the simulated environment is irradiated with neutrons emitted from the neutron source. Gamma ray energy signals are then detected at the at least one detector in response to gamma rays produced during nuclear reactions between the neutrons and materials in and of the simulated environment. A characteristic of the simulated environment is then determined along with a characteristic of the at least one detector. The determined characteristics of the simulated environment and of the at least one detector are then correlated to determine at least one correction factor.

An imaging spectral device for use in the spectrum image analysis for performing the spectroscopic analysis of the respective points in two dimensional field is disclosed. The device comprises an imaging spectral device composing a white-light source to illuminate an object to be measured, a tunable filter located in the optical path between the object and the white-light source, a driving mechanism for wavelength scanning of the tunable filter, and a control unit in which scanning rate of transmitting wavelength of the tunable filter is controlled by the above-mentioned driving mechanism in such a manner that the spectral transmittance of the tunable filter integrated within the exposure time becomes desired spectral distribution of the object to be measured.

A calibration light source outputs emission lines having a known emission-line wavelength, a spectral luminometer to be calibrated measures an emission-line output of the calibration light source, and a system control unit calibrates the wavelength of the spectral luminometer by estimating the wavelength of the emission-line output from ratios of outputs of a light receiving unit at a plurality of measurement wavelengths neighboring an emission-line wavelength and estimating a wavelength change amount from a difference between the estimated wavelength of the emission-line output and the known emission-line wavelength. The wavelength and the sensitivity of a spectral luminometer can be calibrated at a user side.

Systems and methods for hyper-resolution beyond the diffraction limit of optical microscopes for applications in spectroscopy, absorption and lithographic photochemical patterning are described. These systems are based on interference of a pump pulse and a Stokes laser pulse which interfere to localize the population of an excited vibrational state in an area that is smaller than the scanning resolution of the microscope. Another (interfering) Stokes pulse has an annular shape at focus and destructively interferes with the the Stokes laser pulse. This destructive interference causes narrowing of the population distribution of the vibrational excited state well below the diffraction limit, which in turn localizes the population of the central electronic excited state by a separate actinic laser pulse having a lower energy than the ground state excitation energy of the molecule.A stepped photolithography system uses two photomasks to produce photoresist images capable of printing features smaller than 10 nm.

Performance and reliability of microelectromechanical system (MEMS) components enhanced dramatically through the incorporation of protective thin film coatings. Current-generation MEMS devices prepared by the LIGA technique employ transition metals such as Ni, Cu, Fe, or alloys thereof, and hence lack stability in oxidizing, corrosive, and / or high temperature environments. Fabrication of a superhard, self-lubricating coating based on a ternary boride compound AlMgB14 is described in this letter as a potential breakthrough in protective coating technology for LIGA microdevices. Nanoindentation tests show that hardness of AlMgB14 films prepared by pulsed laser deposition ranges from 45 GPa to 51 GPa, when deposited at room temperature and 573 K, respectively. Extremely low friction coefficients of 0.04-0.05, which are thought to result from a self-lubricating effect, have also been confirmed by nanoscratch tests on the AlMgB14 films. Transmission electron microscopy studies show that the as-deposited films are amorphous, regardless of substrate temperature; however, analysis of FTIR spectra suggests that the higher substrate temperature facilitates formation of the B12 icosahedral framework, therefore leading to the higher hardness.

A light emitting diode (LED) based detection system is employed for spectroscopy based applications. LEDs are used as monochromatic light sources for applications at specific and pre-defined wavelengths. Spectrographic information is generated using LEDs of different wavelengths ranging from 260 nm to 1400 nm. Multiple wavelength information is generated by coupling light from each LED into an intensity and mode mixing fiber bundle. A dual beam approach of using a reference and a sample photodiode ensures automatic drift correction. Interference filters at the LED input fiber reduce the spectral bandwidth of the monochromatic light emission to a useful 10 nm bandwidth by cutting off the LEDs trailing emission distribution allowing for absorbance measurements similar to typical spectrometers.

A patient interface and a method of installing a patient interface for a spectroscopy kit on a patient. The patient interface includes a butterfly-shaped patient interface with a cap on top of the patient interface and in proximity to an optical head.

The invention is suitable for the spectral imaging technical field, and provides a coded aperture spectral imaging system which comprises a preposition imaging system, a digital micro-mirror, a collimation system, a reflection raster, a microlens array and a detector. The microlens array comprises a plurality of microlenses; the filtering bands of the filtering layer on each microlens are different; the preposition imaging system images an object to be measured on the digital micro-mirror; the image after coded modulation is incident on the reflection raster through the collimation system to perform light splitting; a space spectrum mixing image is obtained after light splitting; a plurality of images are obtained through the microlens array with a filtering function; the detector simultaneously receives the plurality of images, and performs fusion decoding on the plurality of images to obtain the spectral information of the object to be measured. The coded aperture spectral imaging system can maintain system single rapid measurement, and meanwhile substantially improve system spatial resolution.

Embodiments of the invention pertain to a method and apparatus for spectral deconvolution of detector spectra. In a specific embodiment, the method can be applied to sodium iodide scintillation detector spectra. An adaptive chi-processed (ACHIP) denoising technique can be used to remove the results of stochastic noise from low-count detector spectra. Embodiments of the ACHIP denoising algorithm can be used as a stand alone tool for rapid processing of one dimensional data with a Poisson noise component. In a specific embodiment, the denoising technique can be combined with the spectral deconvolution method. Embodiments of the denoising technique and embodiments of the deconvolution method can be applied to any detector material that provides a radiation spectrum. Specific embodiments can incorporate one or more of the following for spectral deconvolution: denoising, background subtraction, detector response function generation, and subtraction of detector response functions. Photopeaks can be rapidly identified, starting at the high-energy end of the spectrum. The detector response functions can be estimated for photopeaks with a combination of Monte Carlo simulations and simple transformations.

An optical system for use in a spectroscopy procedure includes one or more semiconductor diodes configured to generate an input signal beam with a wavelength shorter than 2.5 microns that is amplified and communicated through optical fiber(s) to a nonlinear element configured to broaden the spectral width to at least 50 nm through a nonlinear effect. A subsystem includes lenses or mirrors to deliver an output beam having a broadened spectrum selected to obtain a desired penetration depth and substantially minimize water absorption with a temporal duration greater than about 30 picoseconds to a sample to perform spectroscopy to characterize the sample. The output beam may have a repetition rate between continuous wave and one Megahertz or higher with a time averaged output power of 20 mW or more and a time averaged intensity of less than approximately 50 MW / cm2.

A spectrally controlled light source includes a light source with a spectral distribution repeated with a predetermined spatial period along an input plane so as to produce multiple copies of the spectral distribution separated by the spatial period. All copies are propagated through dispersive optics to produce equally dispersed spectra on an image plane. A periodic modulating element with a given filter period is applied to each of the dispersed spectra to produce corresponding modulated outputs. According to the invention, the spatial period of the light source on the image plane and the filter period of the modulating element are selected so as to produce a resonance effect that greatly enhances the utility of the spectrally modulated source.

A method for calibrating a computed tomographic imaging apparatus having a gantry, a radiation source operable at a plurality of kVp's, and a detector array having a plurality of detector elements includes using a system detection function to estimate signals of each detector element that would have been detected through air and through a given thickness of water to determine estimated datasets. The estimated datasets are used to determine data pair sets each comprising a normalized water projection value and an ideal projection value for each detector element. The method further includes determining and storing a representation of a mapping function of the normalized water projections values to the ideal projection values in a memory of the computed tomographic imaging apparatus as a spectral calibration of the computed tomographic imaging apparatus.

A spectroscopic instrument (38) includes a first optical component (48) for spatial spectral splitting of a polychromatic beam of light (46) impinging onto the first optical component (48), an objective (50), which routes various spectral regions (B1, B2, B3) of the split beam of light (46a, 46b, 46c) onto differing spatial regions (52a, 52b, 52c), and a sensor (54), situated downstream of the objective (50) in the beam path of the beam of light (46a, 46b, 46c), with a plurality of light-sensitive sensor elements (54a, 54b, 54c). The sensor elements (54a, 54b, 54c) are arranged in the beam path of the split beam of light 46a, 46b, 46c in such a manner that each sensor element (54a, 54b, 54c) registers the intensity of a spectral sector (A1, A2, A3) of the beam of light (46) and the medians (Mk1, Mk2, Mk3) of the spectral sectors (A1, A2, A3) are situated equidistant from one another in the k-space, where (k) denotes the wavenumber.

The invention belongs to the field of ultra-fast laser micro-nano processing and discloses an ultra-fast laser micro-nano processing device with an online monitoring function. The device comprises a laser unit, a dichroic mirror, a microscope, an object carrying platform and an imaging spectrometer. The laser unit is used for outputting two paths of pulsed laser with different wavelengths, and thefirst path of pulsed laser is divided into a first light beam and a second light beam, wherein the first light beam carries out laser micro-nano processing. The second light beam is combined with thesecond path of pulsed laser for spectral imaging and is combined with the first light beam at the same time. After passing through the dichroic mirror and the microscope, the combined light beams areconcentrated on an object to be processed so as to carry out cooperative laser micro-nano processing and real-time monitoring of spectra and imaging; and then non-linear optical signals such as backward coherent anti-stokes raman scattering generated by the object to be processed are collected backward and are to be received by an imaging spectrometer so as to realize real-time monitoring in theprocessing process. Through the ultra-fast laser micro-nano processing device, ultra-fast laser micro-nano processing with nonlinear imaging and spectrum online monitoring functions is realized.

A method for detecting death process of a cell or tissue of a living subject. In one embodiment, the method includes the steps of illuminating the cell or tissue of the living subject with a coherent light, collecting fluorescent light returned from the illuminated cell or tissue of the living subject, identifying a NAD(P)H peak of a spectrum of the collected fluorescent light with a wavelength, λpeak, and obtaining the intensity of the NAD(P)H peak of the spectrum of the collected fluorescent light substantially corresponding to the wavelength λpeak. These steps are repeated at sequential stages until the intensity of the NAD(P)H peak of the spectrum at a current stage is less than the intensity of the NAD(P)H peak of the spectrum at an earlier stage immediately prior to the current stage so as to detect death process of the cell of the living subject at the current stage using the intensity of the NAD(P)H peak of the spectrum.