369 results about "Optical tomography" patented technology

A high performance imaging system for diffuse optical tomography is disclosed. A dense grid utilizing sources, e.g., light emitting diodes (“LEDs”), that achieve high performance at high speed with a high dynamic range and low inter-channel crosstalk are complemented by a system of discrete, isolated receivers, e.g., avalanche photodiodes (“APDs”). The source channels have dedicated reconfigurable encoding control signals, and the detector channels have reconfigurable decoding, allowing maximum flexibility and optimal mixtures of frequency and time encoding and decoding. Each detector channel is analyzed by dedicated, isolated, high-bandwidth receiver circuitry so that no channel gain switching is necessary. The resulting improvements to DOT system performance, e.g., increased dynamic range and decreased crosstalk, enable higher density imaging arrays and provide significantly enhanced DOT image quality. A processor can be utilized to provide sophisticated three dimensional modeling as well as noise reduction.

A system for tomographic imaging includes a source of at least partially coherent radiation, a frequency-swept laser source and an interferometer. The radiation in the interferometer is phase modulated at a modulation frequency for elimination of DC and autocorrelation noises as well as the mirror image. The interference fringes of the radiation backscattered from the sample into the interferometer are detected to obtain a spectral signal. The spectral signal of the detected backscattered interference fringes is transformed to obtain a location dependent signal at each pixel location in a data window. A tomographic image of the fluid flow in the data window is generated for display and of the structure of the scanned fluid flow sample in the data window from the location dependent signal is generated.

Uterine cervical cancer Computer-Aided-Diagnosis (CAD) according to this invention consists of a core processing system that automatically analyses data acquired from the uterine cervix and provides tissue and patient diagnosis, as well as adequacy of the examination. The data can include, but is not limited to, color still images or video, reflectance and fluorescence multi-spectral or hyper-spectral imagery, coherent optical tomography imagery, and impedance measurements, taken with and without the use of contrast agents like 3-5% acetic acid, Lugol's iodine, or 5-aminolevulinic acid. The core processing system is based on an open, modular, and feature-based architecture, designed for multi-data, multi-sensor, and multi-feature fusion. The core processing system can be embedded in different CAD system realizations. For example: A CAD system for cervical cancer screening could in a very simple version consist of a hand-held device that only acquires one digital RGB image of the uterine cervix after application of 3-5% acetic acid and provides automatically a patient diagnosis. A CAD system used as a colposcopy adjunct could provide all functions that are related to colposcopy and that can be provided by a computer, from automation of the clinical workflow to automated patient diagnosis and treatment recommendation.

Light emitted from a light source is divided into measuring light and reference light. The reflected light from the object and the reference light are superposed. Interference light of the reflected light and reference light which have been superposed is detected. Intensities of the reflected light in a plurality of positions in the direction of depth of the object are detected on the basis of the frequency and the intensity, and a tomographic image of the object is obtained on the basis of the intensity of the reflected light in each position in the direction of depth. A compensating signal is obtained by removing the spectral components of the measuring light from an interference signal obtained by detection of the interference light, and the compensating signal is provided for detection of the intensities of the reflected light after a Gaussian transform.

The present invention provides systems, methods and apparatuses that perform digital detection for use in optical tomography. Methods and systems are provided in which digital lock-in detection is performed using an algorithm that employs a phase-independent quadrature technique. Methods and systems are provided in which a unique manipulation of an ordinary averaging filter optimized for sources discrimination and the consequent sampling constraints is presented as a novel filtering scheme for the lock-in detection. Systems and apparatuses are provided which include a digital signal processor which performs digital lock-in detection and an integrated complex programmable logic device for timing control. Apparatuses are provided which include an instrument having an integrated digital signal processor for performing digital processing and detection for use in optical tomography.

An optical probe includes a tubular outer envelope and a optical fiber which extends in the longitudinal direction of the outer envelope inside the outer envelope. By fixing a light deflecting element to the optical fiber and rotating the optical fiber by a driver, the light deflecting element is rotated. A protective member which has a higher resistance to wear than the outer peripheral surface of the optical fiber is fixed to a part of the outer peripheral surface of the optical fiber in a position near the front end of the optical fiber and is borne for rotation by a bearing portion on the probe outer envelope.

When reflection light, reflected from a measurement target that has been irradiated with measurement light in such a manner to scan the measurement target, and reference light are combined in each wavelength sweep, interference light is detected as interference signals. When a thinning region in which the interference signals obtained by detecting the interference light in each wavelength sweep are thinned so that the interference signals that are used to produce the tomographic image remain is set, thinning is performed on the plurality of interference signals in the thinning region. Light intensity information about the measurement target in the thinning region is obtained, based on the interference signals for the respective wavelength sweeps, the interference signals remaining after thinning. The tomographic image in the thinning region is produced based on the obtained light intensity information.