8797results about "Photometry" patented technology

The Laser Induced Fluorescence Attenuation Spectroscopy (LIFAS) method and apparatus preferably include a source adapted to emit radiation that is directed at a sample volume in a sample to produce return light from the sample, such return light including modulated return light resulting from modulation by the sample, a first sensor, displaced by a first distance from the sample volume for monitoring the return light and generating a first signal indicative of the intensity of return light, a second sensor, displaced by a second distance from the sample volume, for monitoring the return light and generating a second signal indicative of the intensity of return light, and a processor associated with the first sensor and the second sensor and adapted to process the first and second signals so as to determine the modulation of the sample. The methods and devices of the inventions are particularly well-suited for determining the wavelength-dependent attenuation of a sample and using the attenuation to restore the intrinsic laser induced fluorescence of the sample. In turn, the attenuation and intrinsic laser induced fluorescence can be used to determined a characteristic of interest, such as the ischemic or hypoxic condition of biological tissue.

An apparatus for immersion optical lithography having a lens capable of relative movement in synchrony with a horizontal motion of a semiconductor wafer in a liquid environment where the synchronous motion of the lens apparatus and semiconductor wafer advantageously reduces the turbulence and air bubbles associated with a liquid environment. The relative motions of the lens and semiconductor wafer are substantially the same as the scanning process occurs resulting in optimal image resolution with minimal air bubbles, turbulence, and disruption of the liquid environment.

A network for power transmission to a receiver that converts the power into current includes a first node for transmitting power wirelessly in a first area. The first area has a minimum electric or magnetic field strength. The network includes a second node for transmitting power wirelessly in a second area. The second area has a minimum electric or magnetic field strength and overlaps the first area to define an overlap area. In another embodiment, the network includes a source in communication with the first and second nodes which provides power to them. Also disclosed are methods for power transmission to a receiver that converts the power into current.

Disclosed are photoluminescent fibers containing photoluminescent phosphorescent materials and photoluminescent fluorescent materials whose emission signature lies partly or fully in the infrared region of the electromagnetic spectrum. Also disclosed are the use of the inventive fibers, fabrics made therefrom, and objects containing the fiber.

Disclosed is a method for converting a primary electromagnetic radiation to a longer output wavelength that includes providing an energy conversion layer having a first photoluminescent material and a second photoluminescent material, exposing the energy conversion layer to the primary electromagnetic radiation, and transferring at least a portion of absorbed energy from the first photoluminescent material to the second photoluminescent material by dipolar coupling, such that the second photoluminescent material subsequently emits the longer output wavelength.

A low rare earth mineral photoluminescent structure for generating long-persistent luminescence that utilizes at least a phosphorescent layer comprising one or more phosphorescent materials having substantially low rare earth mineral content of less than about 2.0 weight percent, and one or more fluorescent layers is disclosed. Further disclosed are methods for fabricating and using the inventive low rare earth mineral photoluminescent structure. A low rare earth mineral photoluminescent composition for generating long-persistent luminescence that utilizes at least one or more phosphorescent materials having substantially low rare earth mineral content of less than about 2.0 weight percent and one or more fluorescent materials is also disclosed, as well as, the methods for fabricating and using the inventive low rare earth mineral photoluminescent composition.

An assay result reader, for use in conjunction with an assay device comprising a porous liquid-permeable carrier in the form of a strip or sheet through the thickness of which electromagnetic radiation is transmissible, the carrier including a detection zone in which an assay result is revealed by specific binding of a detectable material directly or indirectly to a binding agent immobilized in the detection zone, detection of the detectable material being effected by determining the extent to which electromagnetic radiation transmitted through the thickness of said carrier is attenuated by the presence of the detectable material bound in the detection zone.

The invention provides imaging apparatus and methods useful for obtaining a high resolution image of a sample at rapid scan rates. A rectangular detector array having a horizontal dimension that is longer than the vertical dimension can be used along with imaging optics positioned to direct a rectangular image of a portion of a sample to the rectangular detector array. A scanning device can be configured to scan the sample in a scan-axis dimension, wherein the vertical dimension for the rectangular detector array and the shorter of the two rectangular dimensions for the image are in the scan-axis dimension, and wherein the vertical dimension for the rectangular detector array is short enough to achieve confocality in a single axis.

A method for supplying gas over a substrate in a reaction chamber wherein a substrate is placed on a pedestal, includes: supplying a first gas from a first side of the reaction chamber to a second side of the reaction chamber opposite to the first side; and adding a second gas to the first gas from sides of the reaction chamber other than the first side of the reaction chamber so that the second gas travels from sides of the substrate other than the first side in a downstream direction.

An optical detection and orientation device is provided comprising housing having an excitation light source, an optical element for reflecting the excitation light to an aspherical lens and transmitting light emitted by a fluorophore excited by said excitation light, a focussing lens for focusing the emitted light onto the entry of an optical fiber, which serves as a confocal aperture, and means for accurately moving said housing over a small area in relation to a channel in a microfluidic device. The optical detection and orientation device finds use in identifying the center of the channel and detecting fluorophores in the channel during operations involving fluorescent signals.

An optical reader is suitable for reading 2-dimensional indicia. The optical reading device, that may include a bar code reader, comprises a guide whose length along the optical reader optical axis is such that when that guide contacts the part or equipment surrounding the indicia to be read, that indicia is within the optical reader depth of field. The reader comprises a housing having therein a source of illumination and optics for producing a diverging beam for illuminating indica. A spacing element transparent guide is removably attached to the housing, and does not block indicia. The line of contact of the guide with the data carrier is substantially fully visible to the operator, who can thus confirm that the guide is in proper operating position relative to the indica prior to initiating a reading operation. A reading operation can be initiated by pressing on the guide to actuate a switch, or on a manual trigger.

Self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed together while the ability is retained to identify the sensor type and location of each sensor in a random dispersion of large numbers of such sensors in a sensor array using an optically interrogatable encoding scheme, resulting in a microsphere-based analytic chemistry system. Individual microsphere sensors are disposed in microwells at a distal end of a fiber bundle and are optically coupled to discrete fibers or groups of fibers within the bundle to form an optical fiber bundle sensor. The identities of the individual sensors in the array are self-encoded by exposing the array to a reference analyte while illuminating the array with excitation light energy. A single sensor array may carry thousands of discrete sensing elements whose combined signal provides for substantial improvements in sensor detection limits, response times and signal-to-noise ratios.

A network for power transmission to a receiver that converts the power into current includes a first node for transmitting power wirelessly in a first area. The first area has a minimum electric or magnetic field strength. The network includes a second node for transmitting power wirelessly in a second area. The second area has a minimum electric or magnetic field strength and overlaps the first area to define an overlap area. In another embodiment, the network includes a source in communication with the first and second nodes which provides power to them. Also disclosed are methods for power transmission to a receiver that converts the power into current.

A method and apparatus for curing photosensitive materials uses LEDs and an optical concentrator to generate high optical power intensities. An LED array, comprising a plurality of LED assemblies, generates collimated light. A collection lens functions as an optical concentrator and focuses the collimated light to a desired spot size at a desired location. The LED assemblies may be at least partially disposed in a cooling plenum, where the cooling plenum is at least partially defined by the collection lens. Each LED assembly within the LED array may be detachably coupled to a mounting surface, enabling easy replacement of individual LED assemblies within the LED array. The photocuring assembly may also include a redirecting assembly disposed between the collection lens and the desired location that may further concentrate the light at the desired location. The photocuring assembly may include more than one of the above features.

A safety indicator monitors environment conditions detrimental to humans e.g., hazardous gases, air pollutants, low oxygen, radiation levels of EMF or RF and microwave, temperature, humidity and air pressure retaining a three month history to upload to a PC via infra red data interface or phone link. Contaminants are analyzed and compared to stored profiles to determine its classification and notify user of an adversity by stored voice messages from, via alarm tones and associated flashing LED, via vibrator for silent operation or via LCD. Environmental radiation sources are monitored and auto-scaled. Instantaneous radiation exposure level and exposure duration data are stored for later readout as a detector and dosimeter. Scans for EMF allow detection with auto scaling of radiation levels and exposure durations are stored for subsequent readout. Electronic bugs can be found with a high sensitivity EMF range setting. Ambient temperature measurements or humidity and barometric pressure can be made over time to predict weather changes. A PCS RF link provides wireless remote communications in a first responder military use by upload of alarm conditions, field measurements and with download of command instructions. The link supports reception of telemetry data for real time remote monitoring of personnel via the wrist band for blood pressure, temperature, pulse rate and blood oxygen levels are transmitted. Commercial uses include remote environmental data collection and employee assignment tasking. GPS locates personnel and reporting coordinates associated with alarm occurrences and associated environmental measurements.

A multi-dimensional imaging device and method for automated exposure control that implement two distinct modules to control the exposure and gain settings in the imager so that processing can occur in a multi-tasking single CPU environment. The first module, referred to herein as the imager control module, controls the exposure and gain settings in the imager. The first module is typically implemented in a high priority routine, such as an interrupt service routine, to insure that module is executed on every captured frame. The second module, referred to herein as the histogram processing module, calculates a target contrast (the product of the targeted exposure and gain settings) based on feedback data from the first module and image data from memory. The second module is typically implemented in a low priority routine, such as a task level routine, to allow for the routine to be executed systematically in accordance with priority.

The invention provides imaging apparatus and methods useful for obtaining a high resolution image of a sample at rapid scan rates. A rectangular detector array having a horizontal dimension that is longer than the vertical dimension can be used along with imaging optics positioned to direct a rectangular image of a portion of a sample to the rectangular detector array. A scanning device can be configured to scan the sample in a scan-axis dimension, wherein the vertical dimension for the rectangular detector array and the shorter of the two rectangular dimensions for the image are in the scan-axis dimension, and wherein the vertical dimension for the rectangular detector array is short enough to achieve confocality in a single axis.

Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains that direct excitation radiation to and emitted signals from such arrays and image the signals onto detector arrays, from which such signals may be subjected to additional processing.

Method and system are disclosed for de-embedding optical component characteristics from optical device measurements. In particular, the invention uses frequency domain averaging of the RBS on both sides of an optical component to determine one or more of its optical characteristics. Where the RBS has a slope (e.g., as in the case of a lossy fiber), a frequency domain least square fit can be used to determine the optical component characteristics. In addition, the invention uses a reference DUT to correct for variations in the frequency response of the photoreceiver. A reference interferometer is used in the invention to correct for sweep non-linearity of the TLS. The optical component characteristics are then de-embedded from optical device measurements to provide a more precise analysis of the optical device.

A system and method for knee arthroplasty procedures, using a novel leg rotation fixture to enable the leg mechanical axis, the tibia and the femur to be mutually disposed such that the load bearing, mechanical axis of the leg runs through the center of the knee joint. A measurement gauge is provided for mounting on the tibia and for aligning a baseplate in a known position on the tibia. This baseplate supports an X-ray target plate in a known position relative to the tibia, used in determining the mechanical axis, and an optional surgical robot, used to perform tibial and femoral cuts. The position of the femur relative to the robot may be determined from X-ray imaging of the pelvic region after attachment to the baseplate of an additional target extending to the pelvic region. The system enables improvement in the accuracy of knee arthroplasty procedures.

A system for conducting a polymerase chain reaction (PCR) assay upon a collection of samples is disclosed. The PCR assay is performed by absorption detection. The system includes a multi-well plate which is adapted to retain a collection of sample wells. This system includes a thermal cycler for the multi-well plate. The system additionally includes a collection of photodetectors, and a corresponding number of light sources. The light sources are positioned such that light emitted from each of the respective light sources passes through a corresponding well retained in the multi-well plate and to a corresponding photodetector. The system also includes a processor or other means for analyzing the output signals from the photodetectors. In certain versions of the system, ultra-violet light is used.

A particle beam irradiation system capable of ensuring a more uniform dose distribution at an irradiation object even when a certain time is required from output of a beam extraction stop signal to the time when extraction of a charged particle beam from an accelerator is actually stopped. The particle beam irradiation system comprises a synchrotron, an irradiation device including scanning magnets and outputting an ion beam extracted from the synchrotron, and a control unit. The control unit stops the output of the ion beam from the irradiation device in accordance with the beam extraction stop signal, controls the scanning magnets to change an exposure position in a state in which the output of the ion beam is stopped, and after the change of the exposure position, starts the output of the ion beam from the irradiation device again. The control unit further outputs a next beam extraction stop signal when an increment of dose integrated from the time of a preceding beam extraction stop signal as a start point reaches a setting dose stored in advance.

A system and method for imaging biological samples on multiple surfaces of a support structure are disclosed. The support structure may, for instance, be a flow cell through which a reagent fluid is allowed to flow and interact with the biological samples. Excitation radiation from at least one radiation source may be used to excite the biological samples on multiple surfaces. In this manner, fluorescent emission radiation may be generated from the biological samples and subsequently captured and detected by detection optics and at least one detector. The captured and detected fluorescent emission radiation may then be used to generate image data. This imaging of multiple surfaces may be accomplished either sequentially or simultaneously. In addition, the techniques of the present invention may be used with any type of imaging system. For instance, both epifluorescent and total internal reflection (TIR) methods may benefit from the techniques of the present invention. In addition, the biological samples imaged may be present on the surfaces of the support structure in a random special pattern and need not be at known locations in order for the imaging to be performed.

A method of fabricating an infrared detector, a method of controlling the stress in a polycrystalline SiGE layer and an infrared detector device is disclosed. The method of fabricating includes the steps of forming a sacrificial layer on a substrate; patterning said sacrificial layer; establishing a layer consisting essentially of polycrystalline SiGe on said sacrificial layer; depositing an infrared absorber on said polycrystalline SiGe layer; and thereafter removing the sacrificial layer. The method of controlling the stress in a polycrystalline SiGe layer deposited on a substrate is based on varying the deposition pressure. The infrared detector device comprises an active area and an infrared absorber, wherein the active area comprises a polycrystalline SiGe layer, and is suspended above a substrate.

A fluorescence detecting apparatus which allows highly precise measurement of fluorescence even with minute sample amounts, which has a strong responsiveness to temperature variations, which allows simultaneous measurement of a plurality of samples, and wherein the light source and the container holder, and the container holder and the fluorescence detector, are each optically connected by optical fibers; and the optical fibers are connected to the container holder in such a manner that the sample in the container is excited for fluorescence from below the sample container held by the container holder, and that they may receive the fluorescent light which is emitted by the sample from below the sample container.