87 results about "Intensity-modulated radiation therapy" patented technology
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Intensity modulated radiation therapy (IMRT) uses advanced software to plan a precise dose of radiation, based on tumor size, shape and location. A computer-controlled device called a linear accelerator delivers radiation in sculpted doses that match the 3D geometrical shape of the tumor, including concave and complex shapes.
Various embodiments of the present invention provide methods and systems for deterministic calculation of radiation doses, delivered to specified volumes within human tissues and organs, and specified areas within other organisms, by external and internal radiation sources. Embodiments of the present invention provide for creating and optimizing computational mesh structures for deterministic radiation transport methods. In general these approaches seek to both improve solution accuracy and computational efficiency. Embodiments of the present invention provide methods for planning radiation treatments using deterministic methods. The methods of the present invention may also be applied for dose calculations, doseverification, and dose reconstruction for many different forms of radiotherapy treatments, including: conventional beam therapies, intensity modulated radiation therapy (“IMRT”), proton, electron and other charged particle beam therapies, targeted radionuclide therapies, brachytherapy, stereotactic radiosurgery (“SRS”), Tomotherapy®; and other radiotherapy delivery modes. The methods may also be applied to radiation-dose calculations based on radiation sources that include linear accelerators, various delivery devices, field shaping components, such as jaws, blocks, flattening filters, and multi-leaf collimators, and to many other radiation-related problems, including radiation shielding, detector design and characterization; thermal or infrared radiation, optical tomography, photon migration, and other problems.
This invention describes a system for generating multiple simultaneous tunable electron and photon beams and monochromatic x-rays for all field simultaneous radiation therapy (AFSRT), tumor specific AFSRT and screening for concealed elements worn on to the body or contained in a container. Inverse Compton scattering renders variable energy spent electron and tunable monochromatic x-rays. It's spent electron beam is reused for radiation with electron beam or to generate photon beam. Tumor specificradiation with Auger transformation radiation is facilitated by exposing high affinity tumor bound heavy elements with external monochromatic x-rays. Heavy elements like directly iodinated steroid molecule that has high affinity binding to estrogenreceptor in breast cancer and to iodinated testosterone in prostatecancer or with directly implanted nanoparticles into the tumor are exposed with tuned external monochromatic x-rays for tumor specificradiation therapy. Likewise, screening element's atom's k, l, m, n shell specific Auger transformation radiation generated by its exposure to external monochromatic x-rays is used to screen for concealed objects. Multiple beam segments from a beam storage ring or from octagonal beam lines are simultaneously switched on for simultaneous radiation with multiple beams. The beam on time to expose a tumor or an object is only a few seconds. It also facilitates breathing synchronized radiation therapy. The intensity modulated radiation therapy (IMRT) and intensity modulated screening for concealed objects (IMSFCO) is rendered by varying beam intensities of multiple simultaneous beams. The isocentric additive high dose rate from simultaneously converging multiple beams, the concomitant hyperthermia and chemotherapy and tumor specificradiation therapy and the AFSRT's very low radiation to the normal tissue all are used to treat a tumor with lower radiation dose and to treat a radioresistant and multiple times recurrent tumors that heave no other alternative treatments.
Radiation therapy or diagnostic that will ultimately be delivered in a manner that, in addition to being spatially precise, is capable of adapting instantaneously to changes in patient or subject anatomy. The related system and method can adapt to the time dependent geometry of internal patient anatomy and yield a temporally precise IMRT beam that is optimized for the instantaneous configuration of the internal target and avoidance structures.