44 results about "Calcium Phosphate Crystals" patented technology

Methods and compositions are provided which contains preparations of calcium chelators, bisphosphonates, antibiotics, antimicrobial agents, cytostatic agents, calcium ATPase and pyrophosphatase pump inhibitors, calcium phosphate-crystal dissolving agents, agents effective against calcium phosphate-crystal nucleation and crystal growth, and / or a combination of supportive agents and which may be used for treating and or reducing pathological calcifications, the growth of Nanobacterium and calcification-induced diseases including, but not limited to, Arteriosclerosis, Atherosclerosis, Coronary Heart Disease, Chronic Heart Failure, Valve Calcifications, Arterial Aneurysms, Calcific Aortic Stenosis, Transient Cerebral Ischemia, Stroke, Peripheral Vascular Disease, Vascular Thrombosis, Dental Plaque, Gum Disease (dental pulp stones), Salivary Gland Stones, Chronic Infection Syndromes such as Chronic Fatigue Syndrome, Kidney and Bladder Stones, Gall Stones, Pancreas and Bowel Diseases (such as Pancreatic Duct Stones, Crohn's Disease, Colitis Ulcerosa), Liver Diseases (such as Liver Cirrhosis, Liver Cysts), Testicular Microliths, Chronic Calculous Prostatitis, Prostate Calcification, Calcification in Hemodialysis Patients, Malacoplakia, Autoimmune Diseases. Erythematosus, Scleroderma, Dermatomyositis, Antiphospholipid Syndrome, Arteritis Nodosa, Thrombocytopenia, Hemolytic Anemia, Myelitis, Livedo Reticularis, Chorea, Migraine, Juvenile Dermatomyositis, Grave's Disease, Hypothyreoidism, Type 1 Diabetes Mellitus, Addison's Disease, Hypopituitarism, Placental and Fetal Disorders, Polycystic Kidney Disease, Glomerulopathies, Eye Diseases (such as Corneal Calcifications, Cataracts, Macular Degeneration and Retinal Vasculature-derived Processes and other Retinal Degenerations, Retinal Nerve Degeneration, Retinitis, and Iritis), Ear Diseases (such as Otosclerosis, Degeneration of Otoliths and Symptoms from the Vestibular Organ and Inner Ear (Vertigo and Tinnitus)), Thyroglossal Cysts, Thyroid Cysts, Ovarian Cysts, Cancer (such as Meningiomas, Breast Cancer, Prostate Cancer, Thyroid Cancer, Serous Ovarian Adenocarcinoma), Skin Diseases (such as Calcinosis Cutis, Calciphylaxis, Psoriasis, Eczema, Lichen Ruber Planus), Rheumatoid Arthritis, Calcific Tenditis, Osteoarthritis, Fibromyalgia, Bone Spurs, Diffuse Interstitial Skeletal Hyperostosis, Intracranial Calcifications (such as Degenerative Disease Processes and Dementia), Erythrocyte-Related Diseases involving Anemia, Intraerythrocytic Nanobacterial Infection and Splenic Calcifications, Chronic Obstructive Pulmonary Disease, Broncholiths, Bronchial Stones, Neuropathy, Calcification and Encrustations of Implants, Mixed Calcified Biofilms, and Myelodegenerative Disorders (such as Multiple Sclerosis, Lou Gehrig's and Alzheimer's Disease) in humans and animals. The method comprises administering the various classes of compositions of the present invention, which together effectively inhibit or treat the development of calcifications in vivo.

The invention provides a bioactive glass ceramic fiber-PEEK resin composite artificial tooth and a preparation method. The preparation method of the artificial tooth comprises the four steps of preparing hydroxy calcium phosphate crystal glass ceramic fragments, preparing bioactive glass ceramic fibers, preparing the bioactive glass ceramic fiber-PEEK resin composite artificial tooth and conducting surface layer treatment on the portion, implanted into the alveolar bone, of the artificial tooth. The bioactive glass ceramic fiber-PEEK resin composite artificial tooth product prepared according to the method not only has the enough mechanical property, but also has the very good biocompatibility, and the mechanical property, the biocompatibility and the bone bonding strength are all greatly superior to those of a conventional artificial tooth product; in addition, the whole preparation technology process is simple, operation is convenient, and therefore the artificial tooth is very worthy of energetical popularization.

The invention discloses a process for preparing self- growing calcium phosphate crystal whisker tough porous biological ceramic material by using beta-calcium phosphate or hydroxyapatite powder, multiple phase addition agent, zirconium oxide and bonding agent as raw material through the steps of preparing multiple phase addition agent, making slip, modeling, blank pre-calcination and sintering process.

The invention discloses a corrosion and scale inhibitor for the reuse of reclaimed water from production wastewater as circulating cooling water, which comprises the following raw materials by weight: an organic phosphonic acid corrosion and scale inhibitor, PBTC, KW-923, a copper corrosion inhibitor, and deionized production water; the corrosion and scale inhibitor is based on the high-efficientdispersant of KW-923, and is combined with other components such as organic phosphonic acid and copper corrosion inhibitors; through the adsorption and chelation with inorganic scaling microcrystals such as calcium carbonate and calcium phosphate, and organic microparticles in water, the invention can effectively prevent calcium carbonate and calcium phosphate crystals and organic particles from scaling, effectively reduce the corrosion rates of carbon steel and copper, and has good effect of scale inhibition and corrosion inhibition.

The object of the present invention is to provide a calcium phosphate-collagen fiber composite which has an excellent mechanical property, can induce bone replacement by rapid bone remodeling, and can be used in a high-load region. The object can be solved by a porous composite comprising a calcium phosphate crystal and a collagen fiber at a weight ratio of 80:20 to 20:80, wherein (1) a bioabsorbability of the porous composite is graded, and (2) the density of the porous composite determined by gravimetric method is 300 to 1500 mg / cm3.

The invention provides thermoplastic materials for biomedical applications through the processing of soybean de-fatted Tofu cheese. The material films show a relatively high degree of water uptake from the dry state as well as good tensile strength and elastic modulus when tested in wet conditions. The materials minimise in vitro the humoral and cell-mediated inflammatory response, promote the formation of calcium phosphate crystals and undergo a slow degradation in buffer systems. Adhesion and proliferation of tissue cells are favoured by this natural composite material.

Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed.

The invention discloses a controllable preparation method of modified hydroxyapatite powder based on microfluidic control. A micro-channel chip with a Y-shaped structure is used as a reaction container; mineral oil / oleic acid / Span-80 is used as an oil phase containing an emulsifier; an inorganic calcium ion / sodium polyacrylate aqueous solution and an ammonia water / phosphate ion aqueous solution are used as aqueous phases, calcium phosphate crystal nucleuses are formed in the micro-flow droplets and further grow to spherical / shuttle-shaped hydroxyapatite nano particles, the obtained hydroxyapatite nano particles are controllable in particle size, and the particle size of the hydroxyapatite nano particles ranges from 3 nm to 80 nm. The prepared hydroxyapatite nano particles have high dispersity and good biocompatibility, and can be applied to multiple fields of cosmetic sun-screening agents, abrasives, concealer, and the like.

Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed.