64 results about "Bone like apatite" patented technology

The invention discloses a porous polyaryletherketone (PAEK) material with bioactivity, and a preparation method and an application thereof, and belongs to the field of biomedical materials. The method comprises the following steps: carrying out wet uniform mixing on PAEK powder and a calcium phosphate ceramic (CPC) spherical particle pore forming agent to obtain a mixture, filling a die with the mixture, applying a pressure to make the hard pore forming agent be arranged in a close packing approximating manner and remove superfluous PAEK powder, heating the die to realize fusion molding of the PAEK powder under hot pressing in order to obtain a PAEK / CPC body, and immersing the PAEK / CPC body in diluted hydrochloric acid to remove the pore forming agent CPC in order to obtain the porous PAEK material; and processing through concentrated sulfuric acid, and immersing in a simulated body fluid to obtain the bioactive porous PAEK material with a surface bone like apatite layer. The method has the advantages of simple process and good repeatability, and the obtained bioactive material has completely three dimensional through macro-pores and abundant surface micro-pores, and easily adjustable macro-porous dimension and amount of porosity, and can be used to prepare bioactive materials with a gradient pore structure. The bioactive porous PAEK material can be used to restore bone defects, and is especially suitable for being used in interbody fusion cages for spinal column restoration.

The invention relates to a calcium phosphate silicate biomaterial, and a preparation method and a purpose thereof. The calcium phosphate silicate biomaterial is characterized in that a soluble silicon source, a soluble phosphor source and a soluble calcium source are used as raw materials, and water is used as a solvent; a sol-gel method is employed to synthesize pure phase calcium phosphate silicate (Ca5(PO4)2SiO4) powder, which is compressed for moulding and sintered into a calcium phosphate silicate (Ca5(PO4)2SiO4) ceramic block. After soaking the Ca5(PO4)2SiO4 ceramic block in a simulated body fluid (SBF) for 1 day, bone-like apatite can be precipitated on a surface of the ceramic block, and the apatite layer becomes thicker with increasing of a soaking time. The Ca5(PO4)2SiO4 prepared in the invention has good biological performance, is a potential biological and medical material and can be used as a bone restoration and filling material and a restoration material in dentistry.

The invention relates to a preparation method of bone inducing porous titanium artificial bone. The method comprises the following steps: a porous titanium block is processed into a required shape and is washed; the surface is activated; the porous titanium block is put into acid solution which is prepared by sulfuric acid, hydrochloric acid and deionized water to be processed and then is put into alkali solution of sodium hydroxide; or put into acid solution which is prepared by hydrofluoric acid, nitric acid and deionized water to be processed and is then put into hydrogen peroxide solution; or put into acid solution which is prepared by hydrofluoric acid, nitric acid and deionized water to be processed and is then put into hydrogen peroxide solution which contains tantalum pentachloride; the method is characterized in that the surface of the porous titanium can be activated uniformly without pre-depositing a calcium phosphate layer, when being soaked in simulated body fluid at 36.5DEG C, bone-like apatite can be induced to deposit in 28 days; and bone inductivity can be given to the porous titanium artificial bone. The bone inducing porous titanium artificial bone is used for repairing, replacing or reinforcing bone tissue and can reinforce the regeneration of the bone tissue and the interfacial bond of the implant site; and the process is simple and the operation is convenient.