41 results about "5-sulfosalicylic acid" patented technology

The invention provides a preparation process of doxycycline hydrochloride. In the preparation process, 5-hydroxy-6-demethyl-6-desoxy-6-methylene-11-chlorotetracycline is pressurized and hydrogenated with hydrogen in the presence of catalyst-palladium / carbon (Pd / C) and adjuvant and then reacts with 5-sulfosalicylic acid to obtain alpha-6-doxycycline 5-sulfosalicylate; then alpha-6-doxycycline base is generated after basification; and finally the doxycycline hydrochloride is generated through salt transformation. The preparation process of the doxycycline hydrochloride has the advantages that the productivity and stereoselectivity are improved, the content of related substances in the finished product is reduced, and the high-quality finished product is obtained.

The invention relates to a method for preparing conductive non-woven fabric by using an in-situ polymerization method, comprising the following steps of: impregnating the non-woven fabric in a solution consisting of pyrrole, anthraquinone-2-sodium sulfonate or anthraquinone-2,7-sulfonic acid sodium salt and water; dropping a solution consisting of ferric nitrate, 5-sulfosalicylic acid and water into the mixed solution in which the non-woven fabric is impregnated; in the presence of the oxidation of the ferric nitrate, subjecting the pyrrole to in-situ polymerization to synthesize polypyrrole;and forming a conductive layer on the surface of the non-woven fabric through adsorption precipitation of the polypyrrole. The preparation method disclosed by the invention has the advantages of simpleness, low cost, no pollution and mild reaction condition and is suitable for large-scale industrial production. The conductive non-woven fabric prepared by using the preparation method has favorableconductivity, electromagnetic shielding performance, flexible characteristics, and the like.

The invention discloses a rapid analysis method of biogenic amine in fish. The common biogenic amine (nine types of biogenic amine comprising agmatine, histamine, tyramine, spermine, spermidine, 2-phenylethylamine, tryptamine, cadaverine and putrescine) is analyzed in a targeted manner by taking 5-sulfosalicylic acid as an extraction solvent, adopting bead agitating and grinding as an extraction method, taking benzoyl chloride as a derivatization reagent and adopting an LC (liquid chromatogram)-triple tandem quadrupole mass spectrometry. The biogenic amine is detected in a multi-reactions monitoring manner by taking ion pairs with optimum response, which are obtained by optimization, as quantitative ion pairs and taking ion pairs with following response as auxiliary qualitative ion pairs.According to the method, the sample extraction time and the biogenic amine derivation time can be greatly shortened, so that the analysis time of the whole analysis process is greatly shortened. The analysis method has the advantages of being simple in sample pretreatment, rapid in derivation, high in detection sensitivity, high in repeatability and the like.

The invention discloses a purification method of a 5-sulfosalicylic acid. The purification method comprises the following steps: taking industrial-grade 5-sulfosalicylic acid as a raw material, adding a composite cleaning agent made by the company into the raw material, heating, stirring and refluxing, pumping water out and centrifuging after cooling to obtain crude 5-sulfosalicylic acid products, and then obtaining purified 5-sulfosalicylic acid through collecting 5-sulfosalicylic acid products in a conventional method, wherein the purity of the 5-sulfosalicylic acid obtained by the purification method is larger than 99.5%. Compared with the prior art, the purification method has a safe and convenient purification process, saves energy and reduces emission; the composite cleaning agent can be recycled after being activated, so that the requirements of green chemical industry and environment protection are met; and the purified 5-sulfosalicylic acid product is stable in quality, and has an industrial production prospect.

The invention discloses a preparation method of an anticorrosive coating used in a marine environment. The method comprises the following steps: dispersing an aniline monomer into 5-sulfosalicylic acid, performing ultrasonic treatment for 20-40 min, adding a graphene oxide aqueous solution, performing stirring for 20-40 min, performing ultrasonic treatment for 20-40 min, adding ammonium persulfatedropwise, and performing stirring for 11-13 h, wherein a molar ratio of the 5-sulfosalicylic acid to the aniline and a molar ratio of the ammonium persulfate to the aniline are both in a range of 4:5to 5:4; washing the solution obtained after stirring by using deionized water and ethanol for a plurality of times through suction filtration until the cleaning liquid is neutral; performing vacuum drying on the precipitate at 60-70 DEG C for 20-28 h to obtain a graphene oxide / polyaniline composite material; and after nano titanium dioxide is dispersed into the 5-sulfosalicylic acid with a concentration of 0.02-1 M, adding a graphene oxide / polyaniline composite solution with a concentration of 0.25-0.75 mg / ml, performing continuous stirring for 11-13 h, performing centrifugation, performing washing by using distilled water, performing washing by using ethanol, and performing drying to obtain graphene oxide / polyaniline / titanium dioxide composite nanopowder.

The invention provides molecular imprinting. The material of the molecular imprinting is prepared from chitosan and pectin, and one of 5-sulfosalicylic acid, L-tyrosine or R-tyrosine is used as a template molecule. The obtained molecular imprinting has good biocompatibility and biodegradability and low toxicity, is stable for hot solvent, organic solvent and strong acid and strong alkaline solvent, has the performance for resisting the adverse environment, has the advantage of being long in service life, and can meet requirements of the fields having high requirements for toxicity, degradability and the like of biological materials. The preparation process of the molecular imprinting is simple, the molecular imprinting is prepared only by conducting cross-linking reaction on chitosan and pectin in water without using modifier, cross-linking agents or other substances, the production cost is low, the process is safe, and the molecular imprinting is suitable for large-scale industrialized application.

The invention discloses a water-soluble titanocene complex and a synthesis method thereof. The structural formula of the complex is as shown in the specification; and the water-soluble titanocene complex is prepared from titanocene dichloride and 5-sulfosalicylic acid in a mixed system of an organic phase and a water phase at room temperature in the presence of an aromatic carboxylic acid serving as a template catalyst. The complex disclosed by the invention is stable to air and soluble in water; the synthesis method of the water-soluble titanocene complex has the advantages that the used raw materials are cheap and easily available, synthesis steps are simple and feasible; and the post-treatment of the water-soluble titanocene complex is easy, yield is high, and gram-scale preparation of the complex can be realized. The complex disclosed by the invention can be used as a double-acid synergic catalyst or a water-soluble anti-cancer drug.

The invention provides a method which takes PVA (polyvinyl alcohol) as a membrane material and adds PEG (polyethylene glycol) to form a novel asymmetric structure PVA pervaporation membrane through crosslinking and the catalysis-pervaporation membrane is prepared on the basis of the asymmetric membrane. The preparation method belongs to the technical field of membrane separation and comprises thefollowing steps: dissolving the PVA in water, taking the PEG as additive, taking isopropanol for a gel bath, applying an immersion precipitated phase conversion method to prepare the asymmetric PVA membrane, taking glutaraldehyde as cross-linking agent to carry out membrane cross-linking, and dipping the asymmetric PVA membrane in the alcoholic solution of 5-sulfosalicylic acid to apply a chemicalreaction method to prepare the PVA asymmetric catalysis-pervaporation membrane of which the surface and the hole contains a sulfonic acid group. The novel membrane prepared by the invention has the advantages of high flux, good separation effect, high catalytic property and simple technology and has a relatively good application value in ethyl acetate dehydration and acetic acid and ethyl alcoholesterification reaction.

The invention discloses an improved cashmere oxidation-reduction bleaching method, which includes the following steps: (a) pre-treating cashmere with 1-3 wt% of a chelating dispersion agent, 0.5-2 wt% of a surfactant, 2-5 wt% of a penetrating agent, 0.1-0.4 wt% of p-tolyl phenylacetate and 0.5-1 wt% of 2,4,5-trimethyl benzaldehyde; (b) performing oxidation bleaching with 40-47 wt% of hydrogen peroxide, 12-15 wt% of sodium pyrophosphate, 0.75-1.2 wt% of sodium pyridine-3-carboxylate, 1.3-1.5 wt% of potassium methyl malonate, 0.05-0.12 wt% of 2,4-dimethyl phenol and 3.5-5 wt% of 5-sulfosalicylic acid; (c) performing neutralizing washing with 35-45 wt% of isopropyl alcohol, and 3.6-7 wt% of s-butyl-diethyl malonate; (d) performing reduction bleaching with 7-10 wt% of sodium hydrosulfite, 3.5-4 wt% of sodium pyrophosphate, 5-7 wt% of acetic acid, 5-6% of softening agent, 0.65-1 wt% of hydroxyethyl acrylate, and 1.1-1.5 wt% of 2-bromo-2'-fluoroacetophenone, and (e) washing the cashmere with deionized water. The method can reduce damage on scale layer on the cashmere during the bleaching process.

The invention discloses a method for purifying 5-sulfosalicylic acid. The method comprises the following steps of: mixing industrial-grade 5-sulfosalicylic acid serving as a raw material and deionized water to obtain an aqueous solution of 5-sulfosalicylic acid, making the aqueous solution of 5-sulfosalicylic acid pass through active carbon and a 4A molecular sieve in sequence for secondary absorption purification, and collecting by using the common method to obtain the purified 5-sulfosalicylic acid. The purity of the 5-sulfosalicylic acid prepared by the method is more than 99 percent. Compared with the prior art, the method has the advantages that: the purification process is safe and simple, the energy is saved, the emission is reduced, the used active carbon and 4A molecular sieve can be activated to be recycled, and the requirements of green chemical engineering and environmental friendliness are met; and the purified 5-sulfosalicylic acid is stable in quality and has an industrialized production prospect.

The invention discloses a titanocene complex with oxygen-containing carboxylic acid as well as a preparation method and an application of the titanocene complex. The structural formula of the complexis shown in the description. The titanocene complex is prepared from oxygen-containing carboxylic acid as a ligand, titanocene dichloride as Lewis acid and 5-sulfosalicylic acid as a transitional ligand. The complex is stable to air, the raw materials used in the synthesis method are low in cost and easy to obtain, synthesis steps are simple and easy, post-treatment of the product is simple, conditions are mild, and the yield of the target product is high. The complex is used for catalyzing reaction of 2-aminoacetophenone and aromatic aldehyde for synthesis of 2-aryl-2,3-dihydroquinolinone, and better yield is obtained.

The invention provides a pennisetum sinese porous carbon-based solid catalyst and a preparation method thereof, and belongs to the technical field of solid catalyst preparation. The preparation methodof the pennisetum sinese porous carbon-based solid catalyst comprises the following steps: pyrolyzing pennisetum sinese under normal pressure to obtain a pre-carbonized product, activating the pre-carbonized product by using 5-sulfosalicylic acid to obtain an activated precursor, preparing a pennisetum sinese porous carbon carrier through an anaerobic pyrolysis process, and finally, preparing thepennisetum sinese porous carbon-based solid catalyst by adopting 1,4-phenylenediamine-2,5-disulfonic acid diazonium salt as a sulfonating agent. The prepared catalyst can be used for a hydrolysis reaction of cellulose, and the yield of reducing sugar is high. The preparation method disclosed by the invention is simple and feasible and has high catalytic activity and good heat stability, and the main raw materials are reproducible, are low in cost and are environmentally friendly. The method provides a new way for solid catalyst preparation.

The invention discloses an anti-aging back film used for a solar photovoltaic panel. The anti-aging back film comprises a weather-proof layer, an adhesive layer and a carrion-resistant layer from upper to lower in sequence, wherein the weather-proof layer comprises the following components in parts by weight: 50 parts of epoxy resin, 40-42 parts of polyurethane resin, 6-7 parts of paradichlorobenzene, 0.4-0.5 parts of sodium tartrate and 0.4-0.5 parts of 5-sulfosalicylic acid; and the adhesive layer comprises the following components in parts by weight: 50 parts of polymethyl methacrylate, 22-23 parts of propylene-octyl methacrylate copolymer and 2-3 parts of ammonium acetate. According to the scheme, the anti-aging back film is obtained based on improvement on the structure and formula of the conventional back film structure, so that the binding strength between layers is improved; meanwhile, the structural strength, the corrosion resistance, the weather resistance and the anti-aging performance of the single layer body are reinforced; and therefore, the anti-aging back film is relatively long in service life, low in manufacturing cost and easy to popularize and apply.

The invention discloses a weather-resistant film for a solar photovoltaic cell. The weather-resistant film is sequentially provided with a weather-resistant layer, an adhesive layer and an anticorrosive layer from top to bottom, wherein the weather-resistant layer comprises the following raw materials in parts by weight: 50 parts of epoxy resin, 33-35 parts of polyamide resin, 3-4 parts of m-difluorobenzene, 0.6-0.7 part of sodium citrate and 0.4-0.5 part of 5-sulfosalicylic acid; and the adhesive layer comprises the following raw materials in parts by weight: 50 parts of polymethyl methacrylate, 20-22 parts of a propylene-octyl methacrylate copolymer and 2-3 parts of ammonium phosphate. Through dual improvement of traditional film structure and formula, the bonding strength between the layers is improved; meanwhile, the structural strength, the corrosion resistance, the weathering resistance and the ageing resistance of a single-layer body are strengthened; and the weather-resistant film has relatively long service lifetime, and is low in manufacturing cost and easy to popularize and apply.

The invention discloses a method for improving antibacterial performance of a latex mattress. The method comprises the following steps that (1) adiantum capillus-veneris linn, tripterospermum herb, foliage ginkgo biloba, caulis aristolochiae manshuriensis and cinnamomum cassia are dried and smashed, then an ethanol solution is adopted for conducting heating reflux extraction, re-filtering is conducted, a filtered solution is evaporated, and after ethyl alcohol is removed, extracted liquid is prepared; (2) after natural emulsion in a liquid state, the extracted liquid, alpha-olefin sulfonate, 5-sulfosalicylic acid and sodium caseinate are uniformly mixed, helium is introduced in the mixture for foaming treatment, then the mixture is added into a mold, and after thermal evaporation treatment, the antibacterial latex mattress is prepared. The prepared latex mattress is green, environmentally friendly, safe, comfortable and excellent in antibacterial performance.

The invention discloses black ceramic ink powder consisting of the following components mixed in parts by weight: 6-8 parts of hydroxy acrylic resin, 10-12 parts of butyl acrylate, 5-8 parts of azodiisobutyronitrile, 8-10 parts of methyl methacrylate, 5-8 parts of dibutyl phthalate, 100-120 parts of an inorganic black pigment, 20-30 parts of black glaze, 5-6 parts of 5-sulfosalicylic acid, 3-5 parts of cuprammonium sulfate, 5-8 parts of polyethylene wax, 6-8 parts of sodium polyacrylate, 10-12 parts of gas-phase aluminum oxide and 12-15 parts of nano silicon dioxide. The black ceramic ink powder is special type black ceramic ink powder prepared by adding a ceramic sintered pigment into an ink powder formula, a ceramic processing unit can use the black ceramic ink powder to print personalized pictures with extremely-high resolution by using a colored laser printer and the like, and the personalized pictures are directly sintered on ceramic surfaces.

The invention discloses a determination method for cigarette smoke total particle phase induced cell oxidative stress GSH / GSSG. The determination method comprises the following steps that 1, an experiment reagent is prepared; 2, a cigarette smoke total particle phase object is prepared; 3, cell inoculation cultivation is conducted; 4, the contamination of the cigarette smoke total particle phase object is conducted; 5, sample treatment and GSH / GSSG determination are conducted; 6, result analysis is conducted. According to the determination method for the cigarette smoke total particle phase cell induced oxidative stress GSH / GSSG, an SBB buffer solution is used for re-suspending cells, artificial oxidation GSH is prevented, and meanwhile the effective processing time of a sample is increased; in consideration of the fact that protein of active sulfhydryl exists in a cell lysis solution, in order to reduce the situation that sulfide of non-glutathione is combined with DTNB to interfere determination, before sample determination, 5-sulfosalicylic acid is added to be used for removing the protein in the sample, and interference in the determination process is reduced; since the method determines the GSH and the GSSG at the same time, the minusing is used in the result treatment, the concentrations of the GSH and the GSSG can be obtained separately, and the determination method for the cigarette smoke total particle phase cell induced oxidative stress GSH / GSSG has the advantages of being short in time-consuming, simple and convenient to operate, high in sensitivity and reliable in results.

The invention discloses an environment-friendly scale and corrosion inhibitor comprising following components in percentage by weight: 3-5% of polyacrylic acid, 3-10% of zinc sulfate, 0.5-1.5% of 3-(2-thiophene) propionic acid, 1.5-2.5% of 5-sulfosalicylic acid, 0.02-0.05% of ethyl2-chloro-6-fluorophenylacetate, 0.02-0.05% of 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine, and the balance of water. Compared with the prior art, the environment-friendly scale and corrosion inhibitor disclosed by the invention has the beneficial effects of being free of organic phosphonic acid and good in scale and corrosion inhibition effect, and especially obvious in scale and corrosion inhibition effect on circulating water with high hardness and high pH; and the adhesion speed of a carbon steel test tube is reduced to 5.25 mcm, and the corrosion rate of carbon steel is reduced to 0.00684 mm / a, all of which meet the 'very good' standard of Sinopec.

the invention discloses a compound protein precipitant, which is characterized by the following: possessing 1-1.5% 5-sulfosalicylic acid, 75-85% carbinol and 15-25% distilled water; making rate of deposition over 99%; damaging little for chromatographic column through pH at weak acid.

The invention relates to a magnesium alloy pickling activator, a pickling method and a product. The pickling activator comprises the following components according to concentration: 5-20g / L 5-sulfosalicylic acid and 5-10g / L potassium fluoride. The pickling method comprises the steps of: (1) putting a magnesium alloy into a degreasing solution to undergo degreasing so as to remove surface greasy dirt; (2) washing the degreased magnesium alloy, and then placing it in the pickling activator to undergo a pickling activation treatment, with the pickling activator composed of the following components in terms of concentration: 5-20g / L 5-sulfosalicylic acid and 5-10g / L potassium fluoride; (3) washing the pickled magnesium alloy, then putting it into a?surface conditioning?agent to perform a surface conditioning treatment; and (4) washing the magnesium alloy subjected to surface conditioning, and then carrying out a formation treatment. The pickling activator adopts an inorganic acid, does not contain chromium compound, and has the advantage of mild reaction. The method abolishes the work of magnesium alloy surface grinding to save manpower and material resources.

The invention belongs to the technical field of mineral metallurgy, and concretely discloses a leaching method for recovering lead from lead oxide ores, and its leaching agent. The method is characterized in that 5-sulfosalicylic acid is used as a leaching agent to leach lead from the lead oxide ores with the lead level of 14-75%, the leaching temperature is 20-60DEG C, lead oxide ores with the granularity of below 65[mu]m account for 70-96% of the weight of the lead oxide ores, the concentration of 5-sulfosalicylic acid is 0.1-0.5mol / L, the 5-sulfosalicylic acid leaching agent is mixed with lead oxide ore powder according to a liquid / solid mass ratio of 5-20:1, and the obtained mixture is fully stirred for 20-60min to obtain a lead-containing solution suitable for later lead extraction and electrodeposition treatment. The leaching agent has a high leaching rate and is simple to prepare, and the method uses 5-sulfosalicylic acid wastes generated in the pharmacy and chemical industry; and the leaching method guarantees the high lead leaching rate without high temperature or a pressurizing device, and also has the advantages of simple operation and low process cost.

The invention relates to an environment-friendly chemical conversion processing technology for an aluminum alloy, and belongs to the technical field of aluminum alloy surface processing. The environment-friendly chemical conversion processing technology includes the chemical conversion film preparation process steps that a pre-processed aluminum alloy is obtained by conducting the oil removing working procedure, the alkali corrosion working procedure and the acid pickling working procedure on the surface of the aluminum alloy; then, the chemical conversion film forming working procedure and the hole sealing processing working procedure are conducted on the surface of the pre-processed aluminum alloy; wherein chemical conversion processing fluid required by chemical conversion film formingprocessing includes following components, namely, a H3PO4 solution with the concentration being 10 mL / L to 50 mL / L, NaF with the concentration being 3.5 g / L to 10.5 g / L, K2TiF6 with the concentrationbeing 1.0 g / L to 4.0 g / L, Na2WO4 with the concentration being 1.0 g / L to 5.0 g / L and 5-sulfosalicylic acid with the concentration being 1.5 g / L to 5.0 g / L; the pH value of the chemical conversion processing fluid is between 2.00 and 4.00, the conversion temperature is 30 DEG C to 50 DEG C, and the aluminum alloy chemical conversion processing time is 5 min to 15 min; and a solution used for hole sealing processing includes sodium molybdate with the concentration being 10 g / L to 20 g / L. The environment-friendly chemical conversion processing technology is simple in processing technology, low incost, green and environment-friendly, and a formed conversion film has good corrosion resistance.

The invention discloses 5-sulfosalicylic acid functionalized Fe3O4 magnetic nano particles, as well as a synthesis method and application of the nano particles. The 5-sulfosalicylic acid functionalized Fe3O4 magnetic nano particles are formed by wrapping Fe3O4 magnetic nano particles with tetraethyl orthosilicate, and generating reaction between the obtained Fe3O4 / SiO2 magnetic nano particles and 5-sulfosalicylic chloride. The synthesis method of the particles disclosed by the invention is simple; the synthesized particles are spherical, uniform in dimension and high in dispersion property, and have a good adsorption effect on Se speciation; a feasible basis is supplied to research of trace Se speciation in an environment water sample.

The invention discloses an ion exchange agent based on modified resin. The ion exchange agent is prepared by using 5-sulfosalicylic acid to modify Amberlite XAD-4 resin. The ion exchange agent can be used to adsorb Co2+ and Mn2+ in PTA wastewater, and removal rate of the same is up to higher than 90%; the ion exchange agent can realize desorption after being soaked by hydrochloric acid, namely having high renewability.

The invention relates to a magnesium alloy pickling activator, a pickling method and a product. The pickling activator comprises the following components according to concentration: 5-20g / L 5-sulfosalicylic acid and 5-10g / L potassium fluoride. The pickling method comprises the steps of: (1) putting a magnesium alloy into a degreasing solution to undergo degreasing so as to remove surface greasy dirt; (2) washing the degreased magnesium alloy, and then placing it in the pickling activator to undergo a pickling activation treatment, with the pickling activator composed of the following components in terms of concentration: 5-20g / L 5-sulfosalicylic acid and 5-10g / L potassium fluoride; (3) washing the pickled magnesium alloy, then putting it into a?surface conditioning?agent to perform a surface conditioning treatment; and (4) washing the magnesium alloy subjected to surface conditioning, and then carrying out a formation treatment. The pickling activator adopts an inorganic acid, does not contain chromium compound, and has the advantage of mild reaction. The method abolishes the work of magnesium alloy surface grinding to save manpower and material resources.

The invention belongs to the technical field of mineral metallurgy, and concretely discloses a method for leaching ore concentrate from copper oxide ores based on a complexing reaction, and its leaching agent. The method is characterized in that 5-sulfosalicylic acid is used as a leaching agent to leach copper from the copper oxide ores with the copper level of above 15%, the leaching temperature is 20-60DEG C, copper oxide ores with the granularity of below 74[mu]m account for 75-95% of the weight of the copper oxide ores, the concentration of 5-sulfosalicylic acid is 0.05-0.25mol / L, the 5-sulfosalicylic acid leaching agent is mixed with copper oxide ore powder according to a liquid / solid mass ratio of 5-20:1, and the obtained mixture is fully stirred for 25-50min to obtain a copper-containing solution suitable for later lead extraction and electrodeposition treatment. The leaching agent and the leaching method have the advantages of high leaching rate and short leaching time; and the leaching method guarantees the high copper leaching rate without high temperature or a pressurizing device, and also has the advantages of simple operation and low process cost.