Belonging to the field of nano
biomedicine and material, the invention in particular relates to the atomization
ultrasound polarity difference technology for preparing organic
metal anti-
cancer drug-dichloro dicyclopentadienyl
titanium and cis-
platinum nano-particles. The method comprises the following steps: preparing solution A with an appropriate concentration; placing the solution A into a squeezing type
sprayer and spraying the solution A into solution B;
controlling environment temperature to range from 15 DEG C to 25 DEG C, environment
humidity to range from 45% to 50%,
ultrasound intensity to be 100w and jet
mass velocity to range from 0.4mL / min to 0.5mL / min; wherein the whole
reaction system is in an
ultrasound environment. The method of the invention features simple equipment, convenient preparation process and low production cost.
Medicine size and shape of the product can be controlled by controlling conditions such as
medicine concentration in the solution A, reaction time and the like; therefore controlled production of the
medicine is expected to be realized by further studies, thus providing more choices for multi-
drug administration of the
medicine. The method of the invention has the advantages of simple and convenient operation, short
production cycle, controlled production, freedom from addition agent and easy realization of industrialization, thus being of great value for industrialized application and expected to be promoted to achieve large-scale application. In addition, the product features even distribution, difficult agglomeration, high purity and easy realization of industrialized production.