76results about How to "Facilitate the condensation reaction" patented technology

The invention provides a preparation method and application of a high hydrogenation selectivity Au-Pd monatomic alloy catalyst, which belongs to the technical field of organic synthesis. The catalyst adopts MOF with an organic ligand being linked with an amino group as a carrier and adopts chloroauric acid and chloropalladic acid as metal precursors, the addition amount of Au and Pd is adjusted, when the Au loading amount is 1.93 weight percent, and the Pd loading amount is 0.02 to 0.11 weight percent, the monatomic alloy catalyst can be obtained, and the amino group has a decisive effect on the synthesis of the monatomic alloy. When nitrobenzene and benzaldehyde are used as raw materials, and when the raw materials of the prepared Au-Pd0.03@UiO-66-NH2 are completely converted under a mild condition, and 98 percent of N-benzyl aniline target product selectivity can be obtained. A coordination unsaturated metal locus of the MOF carrier can present certain L acidity, and the L acidity and a cyclohexane solvent used in the invention have apparent effect for promoting the condensation of aniline and benzyl alcohol.

A high-temperature heat resistant elastic composite comprising a porous high molecular-weight silicon polymer and a reinforcing material wherein the silicon polymer comprises a silicon resin, silica and boron oxide catalyzed by the boron oxide to form a reaction mass that is polymerized in acetone and to which the silica and boron nitride are added and wherein pores of silicone polymer are filled with a densification resin blend.

The present invention provides a method for preparing n-phenylglycinonitrile, wherein the method comprises a step of executing condensation reaction for generating n-phenylglycinonitrile when the phenylamine and glycolonitrile are used as raw materials. The invention is characterized in that according to the continuous production method, the raw materials continuously pass through a pipe type preheater, a pipe type mixer, a pipe type reactor and a reaction still for executing condensation reaction for generating the n-phenylglycinonitrile. The method of the invention has the advantages of fewer devices, simple and brief technical route, saved costs of man power, device, raw materials, energy, etc., improved operating environment, extraordinary automatic control realization, excellent guaranteed safety production operability and continuity, equitability and stability of production thereby guaranteeing the stability of product quality, increasing the product purity and yield. The product purity in the invention is above 95.5%, and the product yield is above 99.8%.

The invention relates to the technology of accelerating aging of brandy, and in particular relates to a method for quickly aging brandy by controlling irregular oak by oxidation-reduction potential combined high-pressure and micro-aerobic. The method comprises the following steps: putting brandy raw wine into a container; adding irregular oak; introducing oxygen into the brandy raw wine in the container, and applying a certain electric field intensity to control the oxidation reduction potential of the brandy raw wine to be 20mV-200mV. Therefore, extraction on the irregular oak by the brandy raw wine can be accelerated, and the aging time can be shortened. According to the method, the effect of aging the brandy raw wine for 10-30 minutes can be close to that of natural aging for 6-12 months, the aging time can be greatly shortened, and the aging efficiency can be remarkably improved.

The invention discloses a method for synthesizing a cephalosporin intermediate, which comprises the following steps: 1, adding 1-methyl-5-mercaptotetrazole and 7-amino-cephalosporanic acid into acetonitrile with stirring, heating the solution, and adding a boron trifluoride complex compound into the solution; 2, adding a proper amount of active carbon into the solution, stirring and filtering thesolution, washing the carbon by using aqueous solution of acetone containing hydrochloric acid, and merging filtrate; 3, adding the merged filtrate into the aqueous solution of acetone, stirring the solution, slowly dripping alkali solution till the pH value of the solution is 2.0 to 3.5, and growing crystals for 1 to 2 hours; and 4, filtering the solution, transferring the filtrate to another container, reclaiming the acetonitrile and the acetone, washing the obtained crystals twice to trice by using the acetone, filtering the solution, and then drying the crystals under vacuum. Aiming at the problem that the conventional method for synthesizing the cephalosporin intermediate is not suitable for industrialized production, the invention provides the method for synthesizing the cephalosporin intermediate; the method is simple and convenient to operate, is suitable for industrialized production and has high yield; and the prepared 7-ATCA.HCl has high purity.

The invention discloses a preparation method of Glimepiride raw material, which comprises the following steps in sequence: in the presence of K2CO3, a condensation reaction is carried out between a compound A: 4-[2-(3-ethyl-4-methyl-2-keto-3-pyrroline-1-formamido)-ethyl]-benzene sulfonamide and a compound B: trans-4-methyl-cyclohexyl isocyanate of the same molar weight in an organic solvent. The mass ratio of the compound A and K2CO3 is 1:0.8-0.9; the mixture synthetic fluid of a crude Glimepiride product and K2CO3 is filtered in a suction way, and then an extract is added into pure water and dissolved to form a solution. The solution is filtered for removing impurities to obtain the aqueous solution of Glimepiride; a hydrochloric acid solution is added into the aqueous solution of the Glimepiride for acidification and then a crude product is separated; acetone is added into the crude Glimepiride product and then refined, filtered in a suction manner, dried in a vacuum environment to obtain a pure Glimepiride product. The method has the advantages of simplifying the synthetic route, selecting mature intermediates as raw materials, adding K2CO3 for promoting the condensation reaction, avoiding the use of chloroform, reducing the residual organic solvent, and being applicable to industrialized production.

A high-temperature heat resistant elastic composite comprising a porous high molecular-weight silicon polymer and a reinforcing material wherein the silicon polymer comprises a silicon resin, silica and boron oxide catalyzed by the boron oxide to form a reaction mass that is polymerized in acetone and to which the silica and boron nitride are added and wherein pores of silicone polymer are filled with a densification resin blend.

The invention discloses a preparation method of a supported phosphorus-vanadium catalyst and a method for synthesizing methyl acrylate by use of the supported phosphorus-vanadium catalyst, and relates to a preparation method of a catalyst and a method for synthesizing methyl acrylate by use of the catalyst. Through the invention, the technical problem that a catalyst prepared by an existing method is easily deactivated and consequently the catalytic activity is reduced is solved. The preparation method of the catalyst comprises the following steps of: (I) preparing steeping liquid; and (II) preparing a suspension, mixing the suspension with the steeping liquid, evaporating to dryness, firing, grinding and screening to obtain the catalyst. According to the invention, the supported phosphorus-vanadium catalyst prepared by taking three-dimensional ordered macroporous silicon dioxide as a carrier of a supported phosphorus-vanadium active component has a three-dimensional ordered cage structure, and the active center is uniformly supported on the catalyst; the V species in the active component of the catalyst is in amorphous phase and contains species V<4+> and V<5+>; and the aldol condensation reaction is facilitated under the synergistic effect of the species V<4+> and V<5+>. Through the invention, the prepared catalyst is applied to the field of synthesis of methyl acrylate.

The invention discloses methods for producing corrugated paper, natural gas and organic fertilizer from straws. The method for producing the corrugated paper includes: (1) cutting the straws; (2) dedusting by a dry method; (3) dedusting by a water membrane; (4) extracting and washing with hot water to remove sand; (5) hydrolyzing by continuous steaming; (6) sprinkling and collecting; (7) backwashing in multiple stages; (8) grinding into high-concentration liquid firstly; (9) ripening; (10) grinding into high-concentration liquid and low-concentration liquid; (11) producing the corrugated paper. The method for producing the natural gas includes the steps of: (1) subjecting high-concentration wastewater to anaerobic treatment; (2) subjecting the treated wastewater to aerobic treatment; (3) purifying marsh gas obtained from anaerobic treatment to obtain the natural gas. The method for producing the organic fertilizer is also provided. The methods for producing the corrugated paper, the natural gas and the organic fertilizer from straws are environmentally friendly, the wastewater obtained in the processes can be recycled, self-producing capability of pulp for industrial packing paperincluding the corrugated paper and the like can be improved, the difficulty of fibrous material shortage in our country can be alleviated, and reliance on imported waste paper can be reduced.

The invention relates to a flexible inorganic solid-state electrolyte thin film and preparation and application thereof. The flexible inorganic solid-state electrolyte thin film is prepared by compounding graphite oxide and Li6.75La3Zr1.75Nb0.25O12LLZN inorganic solid-state electrolyte particles through electrostatic adsorbent lithium ions. The preparation comprises the following steps of uniformly dispersing an LLZN dispersing liquid, pouring onto a sand core with a filter film, sucking and filtering, then pouring a graphite oxide dispersing liquid, sucking and filtering under the vacuum condition, and drying, so as to obtain the flexible inorganic solid-state electrolyte thin film. The flexible inorganic solid-state electrolyte thin film has the advantages that the preparation method issimple, the cost is low, and the industrialization is easy; the weight of the prepared flexible inorganic solid-state electrolyte thin film is light, the flexibility is good, the ion conductivity is good, and the excellent safety property is realized; the application prospect is broad in the fields of flexible electron energy storage devices, flexible sensing, flexible display and the like.

The invention discloses a preparation method of dapoxetine hydrochloride. The preparation method comprises that 3-chloropropiophenone and naphthol as initial raw materials and (S)-tert-butanesulfinyl amide undergo a condensation reaction in a solvent, the intermediate is reduced through a reducer BH3 and then is further subjected to deprotection, the reaction product undergoes a methylation reaction and the reaction product undergoes a salification reaction to produce dapoxetine hydrochloride. The preparation method has mild conditions, can be operated simply, realizes a low cost, is free of resolution or use of an expensive heavy metal catalyst, has a simple aftertreatment process, has a high product yield, produces the product with high chemical purity and optical purity and is suitable for industrial production.

The invention discloses a method for extracting antibacterial peptide from fermentation liquid. The method comprises the following steps of preparation of seed liquid, preparation of a fermentation culture medium, fermentation, ultra-filtration and separation. The method comprises the following specific steps: firstly, culturing bacillus subtilis, saccharomyces cerevisiae and aspergillus oryzae seed liquid respectively; then, inoculating the seed liquid into a fermentation culture medium prepared from soybean meal powder, bran powder and corn flour for fermenting; performing purification and ultrafiltration on the fermentation liquid to obtain four segments of polypeptide solutions of different molecular weights; performing gel permeation chromatography separation and liquid chromatographyseparation on the polypeptide solutions in sequence to obtain the antibacterial peptide. The method has the beneficial effects that the antibacterial peptide is prepared by fermenting mixed bacteria,and four segments of antibacterial peptide of different molecular weights are obtained after separation and purification, so that waste of active polypeptide in the fermentation liquid is avoided, and the bioactivity of the polypeptide at each molecular weight segment can be researched finely and distinguishingly. Meanwhile, by adopting the method, the separation accuracy, correctness and efficiency of the antibacterial peptide are increased.

The invention discloses a method for extracting active polysaccharide of wheat bran. The method comprises seed liquid preparation, fermentation medium preparation, fermentation and active polysaccharide extraction and concretely comprises inoculating nutrient broth with revived schizophyllum commune, bacillus subtilis, lactic acid bacteria and saccharomyces cerevisiae according to a weight ratio,carrying out culture to obtain a seed liquid, mixing wheat bran, soybean meal, corn core powder, distilled water and a fermentation synergist to obtain a fermentation medium, inoculating a fermentation medium with the seed liquid, carrying out fermentation culture, and extracting the fermented wheat bran through distilled water and an ethanol solution to obtain an active polysaccharide solution. The fermentation synergist can greatly increase the yield of the active polysaccharide. The method can significantly reduce the probability that the wheat bran active polysaccharide is separated alongwith the protein denatured gel and increase the yield and content of the wheat bran active polysaccharide. The wheat bran active polysaccharide can be used as an antioxidant active ingredient to remove free radicals in the body.

The present invention provides a bis(t-butylperoxyisopropyl)benzene (abbreviated as BIPB) production method, wherein a condensation dehydration reaction is performed under a negative pressure condition by adopting di-(2-hydroxyisopropyl)benzene and a t-butyl hydrogen peroxide aqueous solution as raw materials, adopting a perchloric acid aqueous solution as a catalyst, and by adopting toluene as a solvent, such that the loss of t-butyl hydrogen peroxide is reduced, the side effect is less, the conversion rate of the raw materials is improved, the BIPB product having high yield and high purity is obtained, and the production cost is reduced.

The invention discloses an anti-carbon deposition aldol condensation catalyst, which comprises an active component, an anti-carbon deposition agent, an active auxiliary agent and a carrier, and the active component is selected from one or more of inorganic salts of Cs and organic salts of Cs The anti-coking agent is selected from one or more of oxides, chlorides, nitrates, carbonates and organic acid salts of Pt, Rh, Ru, Pd, Ir, Fe, Co and Ni, and the active auxiliary The agent is selected from one or more of soluble salts of La, Ce, Nd, Pr and Pm, and the carrier is silicon dioxide. Through the controllable precursor preparation and catalyst activation process, the obtained catalyst is used to catalyze the aldol condensation reaction of methyl propionate and formaldehyde to prepare methyl methacrylate, which has high catalytic activity, good selectivity, strong anti-coking ability and Features of high stability.

The invention discloses a polyethylene water supply pipe material and a preparation method thereof. The polyethylene water supply pipe material comprises the following raw materials: high density polyethylene, metallocene linear low density polyethylene, composite fillers, hydrogen-terminated silicone oil, hydroxyethyl acrylate, nano-manganese oxide and allyl glycidyl ether, wherein the mass ratioof the hydrogen-terminated silicone oil, the hydroxyethyl acrylate, the nano-manganese oxide to the allyl glycidyl ether is 5-15: 5-10: 5-10: 1-5. The preparation method comprises the following steps: preparation of the raw materials, mixing, molding and the like. Compared with the prior art, a product disclosed by the invention is further improved in the aspects of aging resistance and heat resistance.

The present invention provides an active energy ray-curable coating composition containing (A) a polymerizable unsaturated compound; (B) a photopolymerization initiator; (C) at least one silane coupling agent selected from the group consisting of amino group-containing silane coupling agents and mercapto group-containing silane coupling agents; and (D) at least one chelate compound selected from the group consisting of aluminum chelates and titanium chelates, and a film formation method using the same.Disclosed is an active energy ray-curable coating composition characterized by containing a polymerizable unsaturated compound (A), a photopolymerization initiator (B), at least one silane coupling agent (C) selected from the group consisting of amino group-containing silane coupling agents and mercapto group-containing silane coupling agents, and at least one chelate compound (D) selected from the group consisting of aluminum chelates and titanium chelates. Also disclosed is a method for forming a coating film using such an active energy ray-curable coating composition.

The invention discloses a phosphine and sodium trimetaphosphate preparation method, wherein a mixture of a sodium salt of trivalent phosphate and a sodium salt of pentavalent phosphate is heated to a temperature of 300-400 DEG C to be subjected to a disproportionation and condensation reaction under nitrogen protection so as to obtain phosphine and sodium trimetaphosphate, wherein a sodium-phosphorus ratio of the mixture is 0.93-0.99, and a ratio (P<III> / P<V>) of trivalent phosphorus atoms to pentavalent phosphorus atoms of the mixture is 1-1.34. With the method, decomposition and oxidation of an intermediate product phosphine produced from the reaction are avoided, the important chemical industry material phosphine is collected, the condensation reaction for sodium trimetaphosphate production is promoted in the presence of the phosphine, the high purity sodium trimetaphosphate is obtained, long chain high molecule weight substance production is avoided, the sodium trimetaphosphate process is shortened, environmental pollution is reduced, production energy consumption is reduced, production cost is reduced, the whole production process and the final product meet food industry requirements, and comprehensive utilization is achieved.

The invention discloses a preparation method of a filter tip material, and belongs to the technical field of preparation of filter materials. Based on the principle that olefin and acid halide are subjected to a Friedel-Crafts reaction to generate corresponding [alpha],[beta]-unsaturated ketone, an aluminum chloride solution is dispersed in wood pulp, then mixed gas of propylene and acetyl chloride is introduced into the wood pulp to generate trans-3-pentene-2-ketone, which has a fruity flavor; and unsaturated ketones can react with hydroxyl groups in wood pulp fibers, so that the distance between the fibers and unsaturated ketone molecules is reduced, and the adsorption capacity of the filter tip material on wood offensive gas is enhanced. Roots and rhizomes of Platycodon grandiflorum andlicorice roots in the flavor enhancer can absorb nitrosamine gas in smoke and have the effects of relieving cough and reducing sputum. Sugar in corn flour and protein in egg white can be subjected toa Maillard reaction under a heating condition to generate aroma molecules. Agilawood powder can obviously cover cigarette offensive gas, so that the smoke is fine and mellow, and nitrosamine substances can be converted into nitrosamine salt to be adsorbed in the porous gel of the konjak. The product has a wide application prospect.

The invention discloses a preparation method of antibacterial tipping paper for water-based ink printing and belongs to the technical field of preparation of tipping paper. According to the method disclosed by the invention, by utilizing a principle that a Friedel-Crafts reaction is carried out between olefins and acid halides to produce corresponding alpha, beta-unsaturated ketones, an aluminum chloride solution is dispersed into wood pulp, so that the prepared tipping paper has caramel aroma, and the flavor of cigarettes is improved. According to the preparation method disclosed by the invention, a sweet potato powder is subjected to hydrolytic degradation under the action of a compound activator of zinc chloride and copper chloride and forms an oligomer, and after reaction dehydration,the intermediate product can be promoted to carry out a condensation reaction. The tobacco leaf fibers used in the invention have the characteristics of being long, soft, thin in cell walls and largein cell lumen, the tobacco leaf fibers are easily broomed, namely fibrillated in the pulping process, pigments in the prepared perillae extract powder can serve as printing ink pigments, and after activated carbon is soaked into an acetone solution of the perillae extract, the perillae extract is distributed in all fine pores of the activated carbon and achieves an inhibitory effect on bacteria breeding around, so that the tipping paper has an excellent antibacterial property.

The invention provides a slow release type polyphosphate curing agent, a preparation method and application thereof in preparation of a sodium silicate cured product. The preparation method comprises the steps that silica sol is added to a polyving akohol aqueous solution to obtain a polyving akohol intermediate product, then the polyving akohol intermediate product and polyphosphate are mixed to obtain a polymer packaged polyphosphate curing agent, and fiannly spray drying is performed to obtain the slow release type polyphosphate curing agent. Accoridng to the slow release type polyphosphate curing agent, the preparation technology is relatively simple, the product stability is high, the adaptability is good, and the storage life is long; the adaptation period is long after a lot of the curing agent (50%) and sodium silicate are mixed, the mixture uniformity and the fluidity are good, and various construction methods of pouring, mould pressing, coating and the like are convenient; the defect that the usage amount of the ordinary curing agent is small is overcome, the usage amount of the slow release type curing agent is increased, influences to the adaptation period and the construction operation of the curing agent and sodium silicate mixture are small, the alkali content in the cured product can be reduced greatly, the curing integrity is improved, and the usage performance of the cured product is enhanced.

The present invention provides a method for preparing n-phenylglycinonitrile, wherein the method comprises a step of executing condensation reaction for generating n-phenylglycinonitrile when the phenylamine and glycolonitrile are used as raw materials. The invention is characterized in that according to the continuous production method, the raw materials continuously pass through a pipe type preheater, a pipe type mixer, a pipe type reactor and a reaction still for executing condensation reaction for generating the n-phenylglycinonitrile. The method of the invention has the advantages of fewer devices, simple and brief technical route, saved costs of man power, device, raw materials, energy, etc., improved operating environment, extraordinary automatic control realization, excellent guaranteed safety production operability and continuity, equitability and stability of production thereby guaranteeing the stability of product quality, increasing the product purity and yield. The product purity in the invention is above 95.5%, and the product yield is above 99.8%.

The invention relates to a method for preparing 4-(4-aminophenyl)morpholin-3-one. The method comprises the steps of subjecting p-nitroaniline, which serves as a raw material, to an amidation reaction,performing a catalytic hydrogenation reaction, so as to obtain p-acyl substituted aminoaniline, then, subjecting the p-acyl substituted aminoaniline and 1,4-dioxan-2-oneto an amidation reaction, performing a halogenating reaction or a sulfonylation reaction so as to prepare N-(2-substituent ethyl-oxo-acetyl)p-acyl substituted aminoaniline, then, carrying out a condensation cyclization reaction inthe presence of an alkali so as to obtain 4-(4-substituted acyl aminophenyl)morpholin-3-one, and finally, carrying out acyl protective group removing, thereby obtaining a target product. According tothe method, the raw materials employed are cheap and readily available, the operation is simple and convenient, and the cost is low. An involved reaction of each step is high in activity and high inspecificity, reactions are easily performed, and the product is high in purity and high in yield.

The invention discloses a preparation method of a supported phosphorus-vanadium catalyst and a method for synthesizing methyl acrylate by use of the supported phosphorus-vanadium catalyst, and relates to a preparation method of a catalyst and a method for synthesizing methyl acrylate by use of the catalyst. Through the invention, the technical problem that a catalyst prepared by an existing method is easily deactivated and consequently the catalytic activity is reduced is solved. The preparation method of the catalyst comprises the following steps of: (I) preparing steeping liquid; and (II) preparing a suspension, mixing the suspension with the steeping liquid, evaporating to dryness, firing, grinding and screening to obtain the catalyst. According to the invention, the supported phosphorus-vanadium catalyst prepared by taking three-dimensional ordered macroporous silicon dioxide as a carrier of a supported phosphorus-vanadium active component has a three-dimensional ordered cage structure, and the active center is uniformly supported on the catalyst; the V species in the active component of the catalyst is in amorphous phase and contains species V<4+> and V<5+>; and the aldol condensation reaction is facilitated under the synergistic effect of the species V<4+> and V<5+>. Through the invention, the prepared catalyst is applied to the field of synthesis of methyl acrylate.

The invention relates to a novel method for preparing 1-hydroxy-4-arylamino-anthraquinone. The method comprises the following steps: performing condensation reaction on a mixture of quinizarin and leucoquinizarin and a slight excess of aromatic amine in water containing an anionic surfactant, wherein boric acid or other condensation agents are not used in the reaction; and performing refining treatment on a condensation product with a DMF water solution to obtain 1-hydroxy-4-arylamino-anthraquinone with the purity being above 97.0%, wherein the content of a secondary condensation product in the product is lower than 2.0% and the residual amount of 1, 4-dihydroxyanthraquinone is lower than 1.0%. According to the novel method provided by the invention, by strictly controlling condensation reaction conditions, such as selecting the slight excess of aromatic amine and the anionic surfactant, the condensation reaction stays in the primary condensation state, the secondary condensation reaction is effectively controlled, the generation of double condensation products is reduced, the product purity is improved and the refining difficulty in the late stage is further reduced. Aromatic amine is strictly controlled to be slightly excessive, i.e., the amount meets the reaction requirements and does not need to be recovered; and by using the anionic surfactant, the condensation reaction is effectively promoted and the cost and reaction difficulty are reduced.

The invention provides a micro-foaming rubber runway. The micro-foaming rubber runway comprises micro-foaming rubber particles and a polyurethane adhesive, the polyurethane adhesive is used for adhering and curing the micro-foaming rubber particles to form the micro-foaming rubber runway, the micro-foaming rubber runway layers are stacked and are adhered and cured through a polyurethane adhesive to form the micro-foaming rubber runway layers, the micro-foaming rubber particles are prepared from the following raw materials in parts by weight: 100 parts of ethylene propylene diene monomer, 20-30parts of a reinforcing agent, 3-7 parts of a vulcanizing agent, 3-5 parts of a coupling agent, 5-10 parts of a foaming agent and 1-5 parts of an anti-aging agent, and the foaming agent comprises thefollowing components in parts by weight: 4-8 parts of an AC foaming agent and 1-2 parts of 2, 5-ditert-pentylhydroquinone. The invention provides the micro-foaming rubber runway with good elasticity,good tensile and tear resistance and excellent anti-aging performance and a preparation method of the micro-foaming rubber runway.

The invention relates to a method for synthesizing penoxsulam. The method comprises following steps: 1), 5,8-dimethoxy-[1,2,4]triazole[1,5-c]pyrimidine-2-amine is subjected to condensation with chlorosilane and sodium iodide under the action of nucleophilic alkali, and an intermediate is obtained; 2), the intermediate is subjected to a reaction with 2-(2,2-difluoroethoxy)-6-(trifluoromethyl)benzenesulfonyl chloride, and penoxsulam is produced. According to the method, by means of introduction of a tri-alkylated silicon derivative as the intermediate, the condensation reaction of an amino triazole group and a sulfonyl chloride group can be promoted, the reaction time is effectively shortened, reaction yield is increased, and product quality is improved. Besides, the method is green and environmentally friendly, is free of emission of reagents harmful to the environment and facilitates large-range popularization.