Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

45 results about "Polypyrrole nanoparticles" patented technology

A kind of polysulfone-polypyrrole nanoparticle composite asymmetric ultrafiltration membrane and preparation method thereof

InactiveCN102258950AGood hydrophilic surfaceGood biocompatibilityUltrafiltrationHemodialysisUltrafiltration
The invention discloses a preparation method of a polysulfone-polypyrrole nano particle composite asymmetric ultrafiltration membrane. That is, using polysulfone as the matrix membrane material and highly dispersed polypyrrole nanoparticles as the filler, polysulfone-polypyrrole nanoparticles composite asymmetric ultrafiltration membranes with different compositions were prepared by solvent blending and phase transfer. The preparation method of the invention requires simple equipment, convenient operation, low production cost and no post-treatment. The polypyrrole nanoparticles in the obtained composite membrane are uniformly dispersed in the polysulfone, and the obtained membrane has no pollution. During the preparation process, the pore structure, hydrophilicity and chargeability of the membrane are controlled by adjusting the content, particle size and concentration of the casting solution of polypyrrole nanoparticles, so as to optimize the separation performance of the membrane. The resulting composite ultrafiltration membrane is suitable for terminal filtration of various Chinese and Western medicine injections, oral liquids, eye drops, etc., protein separation and purification, and human hemodialysis, etc., especially has a good selective separation function for bovine serum proteins.
Owner:UNIV OF SHANGHAI FOR SCI & TECH

Size-controllable polypyrrole nano particle and preparation method thereof

The invention discloses a size-controllable polypyrrole nano particle and a preparation method thereof. The preparation method comprises the following steps of: dissolving pyrrole and an initiator into a first solvent to form blended solution of pyrrole monomer and the initiator; dissolving an oxidant into a second solvent to form oxidant solution; then mixing the blended solution of the pyrrole monomer and the initiator with the oxidant solution, swaying violently, standing, and after reaction is complete, carrying out centrifugation, washing, drying and the like; and finally, obtaining the size-controllable polypyrrole nano particle. According to the size-controllable polypyrrole nano particle and the preparation method thereof, the preparation step is simple, high in efficiency and high in controllability; the particle size of the obtained size-controllable polypyrrole nano particle is 80-600nm, and the electric conductivity of the obtained size-controllable polypyrrole nano particle is 10<-2>-10<-7>S / cm. The size-controllable polypyrrole nano particle and the preparation method thereof can be used for the application fields such as sensors, actuating devices, artificial muscles, overpotential containers, electrochromic color-changing windows, fuel cells, functional coatings and ultrafiltration membranes.
Owner:UNIV OF SHANGHAI FOR SCI & TECH

Double-nerve-factor connected polypyrrole-polylactic acid parallel conductive porous composite filament membrane and preparing thereof

InactiveCN106075571ALarge amount of connectionsUnique inducing propertiesFilament/thread formingTissue regenerationFiberIn situ polymerization
The invention relates to a two-nerve-factor NGF and NT-3 connected polypyrrole-polylactic acid parallel conductive porous composite filament membrane and a preparing method thereof. Firstly, a parallel porous polylactic acid filament membrane with the diameter ranging from 50 nm to 2000 nm is put into a mixed aqueous solution containing sodium alkyl sulfonate, polyglutamic acid, FeCl3 and pyrrole, then a sufficient reaction is carried out for 2-24 h with an in-situ polymerization method, the surface of the parallel filament membrane is evenly coated with polypyrrole nano-particles, washing and drying are carried out, and then conductive polypyrrole wrapped polylactic acid fiber filament membrane with the diameter ranging from 60 nm to 2500 nm is obtained; then, protein of the two nerve factors, namely, NGF and NT-3, is connected to the parallel conductive porous composite filament membrane in sequence with the carbodiimide technology, and the conducive composite filament membrane which can release nerve factors and promote nerve axon elongation and peripheral nerve repair under electrical field stimulation is obtained. The two-nerve-factor NGF and NT-3 connected polypyrrole-polylactic acid parallel conductive porous composite filament membrane and the preparing method thereof have the advantages that implementation is easy, the nerve factor connection efficiency is high, the material conductivity is high, and the nerve repair time is short.
Owner:SICHUAN UNIV

Cobalt carbonate-polypyrrole composite anode material used for power lithium ion battery and preparation method thereof

The invention discloses a cobalt carbonate-polypyrrole composite anode material used for a power lithium ion battery and a preparation method thereof. The material is in a micro-nano-scale spheroid core-shell structure in which an exterior is a cobalt carbonate core which is coated by polypyrrole. The composite anode material is 3-5 [mu]m in particle sizes. The cobalt carbonate core is assembled by nanometer rods with widths being 20-50 nm. A thickness of a polypyrrole coating layer is 0.3-1 [mu]m. The polypyrrole coating layer is formed, in an aggregation manner, from polypyrrole nanometer particles with particle sizes being 50-100 nm. The preparation method includes following steps: dispersing CoCO3 powder into water in which a surfactant is dissolved to prepare a suspension; adding a pyrrole monomer to the suspension with mixing uniformly; adding ferric chloride to carry out a polymerization reaction; performing a filtering process and collecting a cobalt carbonate-polypyrrole precipitate after the reaction being finished; and performing a washing process and a drying process to obtain the cobalt carbonate-polypyrrole composite anode material. The composite anode material has excellent circulation stability, an excellent rate capability and a very strong capacity recovering capability. In addition, the preparation method is simple and is easy to carry out in large-scale production.
Owner:SHANDONG UNIV

Method for detecting multiple targets based on nucleic acid aptamer fluorescence sensor

The invention discloses a method for detecting multiple targets based on nucleic acid aptamer fluorescence sensor, which applies polypyrrole nanoparticles and DNA silver nanoclusters for the first time and establishes an aptamer sensing platform based on a steric hindrance effect.In addition, the invention obtains a good detection result based on the low non-specific adsorption characteristic ofthe polypyrrole nanoparticles, and realizes the detection of multiple targets based on the specific recognition characteristic of the aptamer sequence, improving the universal performance of the invention.The method for detecting multiple targets based on nucleic acid aptamer fluorescence sensor, provided by the invention, has the advantages of label-free property, no enzyme and high sensitivity,and can realize high-efficiency detection in biological samples.
Owner:NANJING MEDICAL UNIV

Medicine-carried mesoporous silica coated polypyrrole nanoparticles and preparation method thereof

The invention discloses medicine-carried mesoporous silica coated polypyrrole nanoparticles and a preparation method thereof. The preparation method comprises preparation of polypyrrole nanoparticlesand preparation of the medicine-carried mesoporous silica coated polypyrrole nanoparticles. The medicine-carried mesoporous silica coated polypyrrole nanoparticles prepared by the preparation method disclosed by the invention are simple in preparation process, low in production cost and easy in industrial production. On the one hand, the novel nano preparation enters the tumor stroma through an EPR (Enhanced Permeability and Retention) effect of a tumor site to realize passive targeted drug delivery of the tumor, thereby improving the bioavailability of the drug, reducing the toxic and side effects of the drug and enhancing the therapeutic action of the drug; and on the other hand, polypyrrole coated in the novel nano preparation has very high photothermal conversion efficiency, so that the novel nano preparation can simultaneously perform photothermal therapy and realize photoacoustic imaging and has potential clinical application values.
Owner:CHONGQING MEDICAL UNIVERSITY

Polypyrrole-polyvinylpyrrolidone nanoparticles and preparation method and application thereof

The invention provides polypyrrole-polyvinylpyrrolidone nanoparticles are formed by synchronously surface-modifying polyvinylpyrrolidone during pyrrole polymerization process. The method for preparingthe above nanoparticles is also provided and comprises the following steps: separately adding polyvinylpyrrolidone with various molecular weights and concentrations into distilled water, stirring anddissolving, adding an initiator, adding pyrrole, stirring until the polymerization is completed, and centrifugally washing to obtain polypyrrole-polyvinylpyrrolidone nanoparticles with various particle sizes. The application of the above polypyrrole-polyvinylpyrrolidone nanoparticles as pharmaceutical carriers or tumor therapeutic materials is also provided. Polyvinylpyrrolidone is grafted on thesurface of nanoparticles to enhance the colloidal stability thereof and to endow the nanoparticles with good blood compatibility and biocompatibility; and the molecular weight and concentration of the polyvinylpyrrolidone are changed to regulate and control the microscopic morphology of the polypyrrole nanoparticles, thus solving the technical problems in the effect of tumor thermotherapy.
Owner:UNIV OF SHANGHAI FOR SCI & TECH

Novel application of polypyrrole nanoparticle as contrast agent for photoacoustic imaging

The invention discloses novel application of a polypyrrole nanoparticle as a contrast agent for photoacoustic imaging. The polypyrrole nanoparticle comprises solid, mesoporous and hollow structures, shows strong absorption capability in a near-infrared area with wavelength of 500 to 1300 nm and is a high-efficiency near-infrared light thermit. Application of the polypyrrole nanoparticle as the contrast agent for photoacoustic imaging can effectively improve penetration depth of near-infrared laser in tissue, and the polypyrrole nanoparticle has a substantial contrast enhanced effect. Moreover, a polypyrrole nano-material has high conductivity, excellent stability and good biocompatibility; a preparation method for the polypyrrole nanoparticle is simple and green and has low cost; as the contrast agent for photoacoustic imaging, the polypyrrole nanoparticle has wide application prospects.
Owner:PEKING UNIV

Preparation of polypyrrole/gel alginate with three dimensional structure and electrical stimulation and pH response and double control drug release

The invention relates to preparation of polypyrrole / gel alginate with a three dimensional structure and electrical stimulation and pH response and application of the polypyrrole / gel alginate in double control drug release. A preparation method comprises the following steps: preparing nanoparticles of salicylic acid doping polypyrrole, preparing salicylic acid doping polypyrrole nanoparticles / hydrogel alginate and applying the same in the double control drug release. The preparation method has the following advantages that the polypyrrole with the three dimensional structure / hydrogel alginate has electrical stimulation sensibility and drug release behavior of pH response, and that drug release can be controlled dually, and that the preparation method of materials is simple and convenient and feasible, and that the drug release is postponed, and that a drug efficacy is maintained for a longer period of time in a body.
Owner:CHANGZHOU UNIV

Magnetic nanometer diagnosis and treatment agent and preparation method and application thereof

The invention provides a magnetic nanometer diagnosis and treatment agent and a preparation method and application thereof. The magnetic nanometer diagnosis and treatment agent comprises polypyrrole nanoparticles doped with ferroferric oxide nanoparticles and hyaluronic acid adsorbed to the surfaces of the polypyrrole nanoparticles. The nanometer diagnosis and treatment agent is small in grain size, good in penetrability, uniform in grain size, easy to purify, free of obvious cytotoxicity, good in biocompatibility, good in long circulating effect and low in long-term toxicity, and negative charges exist on the surfaces of the particles; an outstanding T2 relaxation enhancement effect is achieved, the linear relation of the T2 relaxation time reciprocal and the iron concentration change within the low concentration range is good, and the nanometer diagnosis and treatment agent has photo-acoustic imaging capability, is an ideal nanometer diagnosis and treatment agent for preparing multi-mode images and is remarkable in photo-thermal and magnetic-thermal treatment effect. The preparation method is simple, conditions are mild, cost is low, and application and popularization are easy.
Owner:THE NAT CENT FOR NANOSCI & TECH NCNST OF CHINA

Near-infrared sensing chip, preparation method and application thereof

The invention discloses a near-infrared light sensing chip based on ion liquid-polypyrrole nano-particles, a preparation method and an application thereof. The near-infrared sensing chip comprises a polydimethylsiloxane substrate, 2 pieces of cover glasses and 2 electrodes; one piece of cover glass attaches to the upper surface of the polydimethylsiloxane substrate while the other attaches to the lower surface of the polydimethylsiloxane substrate, and the two pieces of cover glasses are in seal fit with the upper surface and the lower surface; a through hole is formed in the polydimethylsiloxane substrate and filled with the mixture of polypyrrole nano-particles and ion liquid; the two electrodes pass through the polydimethylsiloxane substrate to contact with the mixture. Compared with a traditional near-infrared sensing chip, the near-infrared sensing chip enables the chip volume and cost to be lowered, is simple in structure, is convenient to operate and has low detection limit to the near infrared.
Owner:RENMIN UNIVERSITY OF CHINA

Preparation method and application of drug-loaded polypyrrole nanoparticles

The invention relates to a preparation method and application of drug loaded polypyrrole nanoparticles. The preparation method comprises the following steps: preparing polypyrrole nanoparticles by taking polyethyleneimine as a stabilizer; carrying out polyethylene glycol modification through amino groups on the surface of polyethyleneimine; loading an anti-cancer drug-adriamycin by utilizing a cavity formed in polyethyleneimine; carrying out in-vitro cancer cell treatment performance evaluation on an obtained final product. The preparation method disclosed by the invention is simple and easy,prepared pegylated polyethyleneimine stabilized polypyrrole / adriamycin composite nanoparticles are good in photothermal effect, stability and biocompatibility, a good combined treatment effect is displayed aiming at cancer cells, and a potential cancer cell treatment application prospect is obtained.
Owner:SOUTHWEST UNIVERSITY

Graphene-polypyrrole nanoparticle composite film electrode and preparation method thereof

The invention provides a graphene-polypyrrole nanoparticle composite film electrode, which is formed by compounding graphene and polypyrrole nanoparticles, wherein the polypyrrole nanoparticles are methyl orange-doped polypyrrole nanoparticles; and the sizes are 50-200nm. The composite film electrode has flexibility, good mechanical property and electrochemical properties, relatively high area capacitance value and volumetric capacitance value and excellent cycling stability and chemical stability. Compared with other film electrodes, the composite film electrode provided by the invention is simple in preparation method and easy to operate; and large-scale and large-area preparation is easy to implement. Adjustment and control on the mechanical property and the electrochemical properties of the graphene-polypyrrole nanoparticle composite film electrode can be achieved through adjustment on the content of the polypyrrole nanoparticles and the thickness of a film; and the composite film electrode has a broad application prospect in the field of energy storage of super capacitors.
Owner:SHANGHAI JIAO TONG UNIV

Preparation method and applications of polypyrrole functional nanoparticles stabilized with protein

The invention discloses a preparation method and applications of polypyrrole functional nanoparticles stabilized with a protein, and belongs to the field of material science and biomedical application. According to the preparation method, water soluble bovine serum albumin (BSA) is taken as a stabilizing agent, potassium peroxydisulfate (KPS) is taken as an initiator, initiation of pyrrole monomerpolymerization is carried out, gadolinium ions (Gd3+) are introduced into a polypyrrole nanoparticle dispersion liquid stabilized by the protein, simulative biomineralization is adopted so as to realize in-suit generation of gadolinium oxide (Gd2O3) in polypyrrole nanoparticles stabilized by the protein. Synchronous diagnosis and treatment is realized, the polypyrrole functional nanoparticles stabilized with the protein possess excellent Ti modal MRI effect and light-heat properties, the preparation method is simple, reaction conditions are mild, the repeatability is high, and popularizationis convenient.
Owner:HUBEI UNIV

Double-targeted-mediated chemotherapy-photothermal combined cancer therapy compound system, preparation method and application of compound system

The invention discloses a folic acid recognition and pillararene nano-valve controlled-release double-targeted-mediated chemotherapy-photothermal combined cancer therapy compound system, a preparationmethod and application of the compound system, and belongs to the technical field of compound medical materials. The preparation method includes that polypyrrole nanoparticles (PPy NPs) are used as anuclear matrix, a metal organic frame material (MOFs) reaction mother solution directly reacts with the nuclear matrix by means of in-situ growth to form a PPy-MOFs compound nanomaterial, and 'connecting shaft' molecules are modified on the PPy-MOFs compound nanomaterial by means of post-modification for subsequent mounting of a pillararene nano-valve mediated by subject-object acting force; polyethyleneimine polymer (PEI-Fa) modified by folic acid is post-modified on a compound material equipped with a supermolecule nano-valve. Design of the whole compound material therapy system brings synergism of all parts into full play, organic combination of chemotherapy and photothermal therapy is realized, and targeted and controlled drug release is realized through controllability of the nano-valve and folic acid recognition.
Owner:JILIN UNIV

Preparation method of nanometer chemotherapeutic drug carrier

The invention discloses a preparation method of a nanometer chemotherapeutic drug carrier. The preparation method comprises the steps that manganese-doped prussian blue nanoparticles and manganese-doped prussian blue@polypyrrole nanoparticles are synthesized firstly, then 4 mg of the manganese-doped prussian blue nanoparticles and the manganese-doped prussian blue@polypyrrole nanoparticles are weighed to be dissolved in a 4 ml of PBS buffer solution, and stirring is conducted to prepare a uniform solution; 1 mg of doxorubicin hydrochloride (DOX) is weighed to be dissolved in a 1 ml of PBS solution and dropped into a nanoparticle solution under the light avoidance condition, and after dropping is finished, 75 mg of sodium hyaluronate is weighed to be added to the solution to be stirred at the low speed for 24 h; and then a dialysis bag with the molecular weight cut-off being 14 KD is selected to conduct light avoidance dialysis for 24 h, and a final product is obtained and placed in a refrigerator at 4 DEG C for light avoidance preservation. The preparation method has great significance in preparing the nanometer chemotherapeutic drug carrier with MRI and PTT functions to load chemotherapeutic drugs, and realizing the nanoparticles with a diagnosis and treatment integrated function.
Owner:HUBEI UNIV +1

Method for preparing welding goggle material

The invention discloses a method for preparing a welding goggle material, and belongs to the technical field of labor protection article preparing. The method includes the steps that polypropylene glycol and a pyrrole monomer serve as raw materials, ferric chloride hexahydrate serve as a catalyst, and polypyrrole nanometer particles are obtained; the polypyrrole nanometer particles are mixed with materials such as polycarbonate L-1225Z and an ultraviolet absorber UV360, the obtained premixed materials and liquid paraffin are mixed and screened, and compounded polycarbonate master batches are obtained; the master batches are subjected to injection molding through an injection molding machine, then an obtained compounded polycarbonate filter lens is cut and smoothed, the lens is finally washed with deionized water and dried, and the welding goggle material can be obtained. The welding goggle material prepared with the method can be subjected to light changing adjustment along with strong and weak change of arc light and distance to arc light of welding persons in the welding process, welding persons can clearly see weldments under all light ray conditions, and the flexibility and safety of the welding person operating are enhanced.
Owner:CHANGZHOU DINGRI ENVIRONMENTAL PROTECTION TECH

Preparation method of conductive reinforced alginate fiber

The invention provides a preparation method of conductive reinforced alginate fiber. The preparation method comprises the following steps that 1, sodium alginate is dissolved in water to prepare a sodium alginate solution; 2, a conductive nano polymer material is added into the sodium alginate solution obtained in step 1 and evenly stirred for ultrasonic dispersion, and a uniformly dispersed mixedsolution is obtained; 3, the mixed solution obtained in step 2 is filtered and subjected to vacuum defoaming, and a spinning solution is obtained; 4, the spinning solution obtained in step 3 is extruded and then solidified into yarn through a coagulating bath, and then washing, rolling and drying are carried out, wherein the conductive nano polymer material is selected from one or more of polyaniline nano particles, polyacetylene nano particles, polypyrrole nano particles and polythiophene nano particles. According to the method, the original advantages of the alginate fiber are guaranteed, the conductivity is also improved, and the method can be applied to the field of textiles.
Owner:珠海阿尔吉科技有限公司

Preparation method of polypyrrole nanoparticles with adjustable photo-thermal conversion capability

The invention discloses a preparation method of polypyrrole nanoparticles with adjustable photo-thermal conversion capability. The method is characterized in that the polypyrrole nanoparticles are prepared through an oxidative polymerization reaction at normal temperature, and synthesis and surface modification of the polypyrrole nanoparticles are synchronously realized. According to the preparation method, the process is simple, compared with a conventional thought, the novel thought does not need temperature control means such as refrigeration, the prepared PPy-PVP NPs have good colloid stability and biocompatibility, and the nanoparticles have high photo-thermal conversion capacity.
Owner:UNIV OF SHANGHAI FOR SCI & TECH

Preparation method of graphene/polypyrrole nanoparticle with negative dielectric constant

The invention relates to a preparation method of a graphene / polypyrrole nanoparticle with a negative dielectric constant and relates to a graphene / polypyrrole nanoparticle preparation method. Comparedwith a dielectric constant epsilon of graphene / polypyrrole synthesized by an existing method, the graphene / polypyrrole nanoparticle prepared by the preparation method disclosed by the invention has the negative value characteristic, and a dielectric constant epsilon of the graphene / polypyrrole nanoparticle is -1.226*10<5> to -398.38. According to the preparation method, a metamaterial is preparedby a material synthesizing method, so that application of the metamaterial in the fields of invisibility, micro antennas, electronic components and the like is beneficial to be expanded. The graphene / polypyrrole nanoparticle prepared by the preparation method disclosed by the invention is in a powder shape and has an even particle size. The preparation method disclosed by the invention can be applied to preparing a nano-composite electromagnetic metamaterial.
Owner:TONGJI UNIV

Preparation method and application of polypyrrole nanoparticles with controllable particle diameters

The invention discloses a preparation method and application of polypyrrole nanoparticles with controllable particle diameters. The preparation method comprises the following steps of S1, preparing astabilizing agent solution, enabling the stabilizing agent solution to reflow, and performing natural cooling to room temperature; S2, dropwise adding an oxidizer to the stabilizing agent solution inS1, and performing uniform stirring to obtain a mixed solution; and S3, dropwise adding a polypyrrole monomer to the mixed solution obtained in S2, continuing to performing stirring for a reaction, and performing dialysis to obtain granular polypyrrole nanoparticles. The proportion of the stabilizing agent in a reaction system is adjusted and controlled, so that the dimension and the size of the polypyrrole nanoparticles can be adjusted and controlled, and the polypyrrole nanoparticles with controllable particle diameters can be obtained. The invention provides a synthesis method which is simple, feasible and green and can be used for massive preparation of the polypyrrole nanoparticles. According to the method, the size of the polypyrrole nanoparticles can be precisely adjusted and controlled, the micro polypyrrole nanoparticles can be prepared, the method can be applied to treatment of tumors by photothermal therapy, can discharge outside bodies from the kidney, and has high use value and clinical development potential.
Owner:SUN YAT SEN UNIV

Polypyrrole nano particle having photo-thermal effect, preparation method and application thereof

The invention belongs to the crossing field of nano engineering and cell biology, and relates to a polypyrrole nano particle having a photo-thermal effect, a preparation method and an application thereof. The nano particle generates heat under irradiation of near infrared ray and can be used for preparing a medicine preparation for treating hemadostenosis caused by inflammatory reaction in blood vessel and vascular smooth muscle cell proliferation. In the invention, on the basis of killing effects on chronic inflammatory cells in vitro with photo-thermal therapy of the nano particle and near infrared laser, an application test of mouse vascular chronic inflammation and in an arteriostenosis model is carried out further, and a result proves that the nano particle can locally enter the focus of the chronic inflammation in artery, and can be used for inhibiting the local chronic inflammation with near infrared ray local irradiation, thereby inhibiting restenosis after intracavitary therapy and being used for evaluating the restenosis after intracavitary therapy through MRI.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Water-based antistatic photocureable coating and preparation method thereof

The invention is applicable to the technical field of photocureable coatings, and provides a water-based antistatic photocureable coating and a preparation method thereof. The preparation method comprises the steps that a polypyrrole nanoparticle aqueous solution serves as a conductive component and is mixed with water-based ultraviolet curing resin, a water-based defoamer, a water-based levelingagent, a photoinitiator and other components, and the preparation of the water-based antistatic photocureable coating can be completed. The method is simple, convenient and easy to implement, and theprepared antistatic photocureable coating does not contain volatile organic solvents, does not need to be heated, and is efficient and environmentally friendly, meanwhile, the conductive component polypyrrole nano-particles have good dispersity and stability in a photocuring system, ideal antistatic performance can be obtained with a small addition amount, and the situation that inorganic conductive particles or conductive polymer powder and the like are dispersed unevenly in the photocuring system after being added as conductive filler is also avoided, agglomeration and precipitation are easily caused, and the viscosity of the system is obviously increased.
Owner:山东亿博润新材料科技有限公司

Preparation method of traditional Chinese medicine molecule doped polypyrrole nanoparticles

The invention discloses a preparation method of traditional Chinese medicine molecule doped polypyrrole nanoparticles. The preparation method comprises the following steps: S1, sequentially dissolving polyvinylpyrrolidone, dopamine and ginsenoside Rh1; S2, adding a pyrrole monomer into the solution in the step S1, and conducting stirring to fully dissolve the pyrrole monomer; S3, adding a ferric chloride hexahydrate solution into the solution in the step S2, fully conducting stirring and mixing, conducting sealing, and conducting stirring for reacting for a period of time; and S4, after the reaction is completed, performing high-speed centrifugation, and performing cleaning with an ethanol / acetone mixed solution to finally obtain the nanoparticles. Conductive polypyrrole is used as a main body, traditional Chinese medicine molecules and polydopamine are jointly used as doping agents, and the nano-particles with photo-thermal rapid and long-acting anti-tumor functions are constructed.
Owner:CHINA-SINGAPORE INT JOINT RES INST

Marker nucleic acid probe, preparation method thereof, test strip and application of polypyrrole nanoparticles

The invention discloses a marker nucleic acid probe and a preparation method thereof, a test strip and application of polypyrrole nanoparticles. Wherein the marker nucleic acid probe comprises a marker and a detection probe loaded on the marker, and the marker is polypyrrole nanoparticles. According to the lateral chromatography test paper, the polypyrrole nanoparticles are creatively adopted as the marker, the polypyrrole nanoparticles have relatively high storage stability, relatively high conductivity and high light stability, and the lateral chromatography test paper based on the polypyrrole nanoparticles can be used for carrying out sensitive and quantitative visual detection on DNA or RNA in a short time; the minimum DNA concentration which can be detected by naked eyes is 1pM, so that the detection sensitivity of the lateral chromatography test paper is greatly improved.
Owner:ANHUI SCI & TECH UNIV

Chitosan drug-carrying composite microsphere with photo-thermal/redox double response and preparation method thereof

The invention discloses a chitosan drug-carrying composite microsphere with photo-thermal / redox double response and a preparation method thereof. The preparation method comprises the following steps:firstly, wrapping polypyrrole nanoparticles and an anti-tumor drug 5-fluorouracil with chitosan to form nano microspheres; secondly, adsorbing carboxymethyl cellulose on an outer layer through electrostatic action; and finally, performing crosslinking by using a disulfide compound to form the composite drug-carrying microspheres. After the drug-carrying system provided by the invention enters intoblood circulation, under the stimulation of high-concentration glutathione in tumor tissues, the drug-carrying system releases anticancer drugs by reductive response, and exerts an anticancer effect.Meanwhile, the prepared nano drug delivery system not only has a thermotherapy effect under near infrared photothermal irradiation, but also can control thermal response of the drugs so as to achievethe purpose of combined therapy.
Owner:NANJING FORESTRY UNIV

A kind of graphene-polypyrrole nanoparticle composite film electrode and preparation method thereof

The invention provides a graphene-polypyrrole nanoparticle composite film electrode, which is formed by compounding graphene and polypyrrole nanoparticles, wherein the polypyrrole nanoparticles are methyl orange-doped polypyrrole nanoparticles; and the sizes are 50-200nm. The composite film electrode has flexibility, good mechanical property and electrochemical properties, relatively high area capacitance value and volumetric capacitance value and excellent cycling stability and chemical stability. Compared with other film electrodes, the composite film electrode provided by the invention is simple in preparation method and easy to operate; and large-scale and large-area preparation is easy to implement. Adjustment and control on the mechanical property and the electrochemical properties of the graphene-polypyrrole nanoparticle composite film electrode can be achieved through adjustment on the content of the polypyrrole nanoparticles and the thickness of a film; and the composite film electrode has a broad application prospect in the field of energy storage of super capacitors.
Owner:SHANGHAI JIAO TONG UNIV

A kind of polypyrrole gel with high conductivity and preparation method thereof

The invention provides high-conductivity polypyrrole gel and a preparation method thereof, belonging to the technical field of conductive high molecular materials. The high-conductivity polypyrrole gel is a porous structure material prepared from polypyrrole nanoparticles through linear assembling and linkage. The preparation method particularly comprises the following preparation steps: mixing anamaranthine aluminon water solution with pyrrole monomers in a certain volume ratio, and carrying out ultrasonic treatment, so as to obtain a solution A; adding a water solution containing ferric ions into the solution A, reacting at the room temperature, and soaking by virtue of a large number of distilled water, so as to obtain polypyrrole gel; and carrying out freeze drying on the gel at -20 DEG C for 2 hours, so as to obtain the high-conductivity polypyrrole gel. The prepared polypyrrole gel has excellent conductivity reaching up to 8.7S / cm-11S / cm and is hopeful to be taken as a new material to be applied to the practical application in the fields of supercapacitors, electromagnetic shielding, electro-catalysis and the like. Besides, the preparation method is convenient in preparationprocess, simple in process and suitable for large-scale production.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY

High-conductivity polypyrrole gel and preparation method thereof

The invention provides high-conductivity polypyrrole gel and a preparation method thereof, belonging to the technical field of conductive high molecular materials. The high-conductivity polypyrrole gel is a porous structure material prepared from polypyrrole nanoparticles through linear assembling and linkage. The preparation method particularly comprises the following preparation steps: mixing anamaranthine aluminon water solution with pyrrole monomers in a certain volume ratio, and carrying out ultrasonic treatment, so as to obtain a solution A; adding a water solution containing ferric ions into the solution A, reacting at the room temperature, and soaking by virtue of a large number of distilled water, so as to obtain polypyrrole gel; and carrying out freeze drying on the gel at -20 DEG C for 2 hours, so as to obtain the high-conductivity polypyrrole gel. The prepared polypyrrole gel has excellent conductivity reaching up to 8.7S / cm-11S / cm and is hopeful to be taken as a new material to be applied to the practical application in the fields of supercapacitors, electromagnetic shielding, electro-catalysis and the like. Besides, the preparation method is convenient in preparationprocess, simple in process and suitable for large-scale production.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products