102 results about "Benzoylformic acid" patented technology

The invention discloses a clean production method of oxidizing 3-methoxy-4-hydroxy mandelic acid for joint production of vanillin and superfine silver powder under an alkaline condition by adopting silver nitrate. The clean production method comprises the following steps: adding a silver nitrate solution, a 3-methoxy-4-hydroxy mandelic acid solution and a sodium hydroxide solution in a parallel flow manner into a reactor, reacting to generate a 3-methoxy-4-hydroxy acetophenone sodium solution and superfine silver powder, filtering and separating the generated silver powder, washing with deionized water and ethyl alcohol sequentially, and drying to obtain the superfine silver powder, wherein the reduction yield of the silver powder is 99.4 per cent to 100 per cent; acidizing filter liquor after the silver powder is separated, performing decarboxylation on 3-methoxy-4-hydroxy benzoylformic acid to generate the vanillin, using methylbenzene to extract the vanillin therein, recycling the methylbenzene solvent, and performing recrystallization on residues in an ethanol aqueous solution to obtain the vanillin, wherein the oxidation yield of the methoxy-4-hydroxy mandelic acid is 95.7 per cent to 98.5 per cent. The silver nitrate is taken as an oxidizing agent to prepare the vanillin, so that the oxidation yield is improved, and the oxidation reaction time is shortened. Two practical fine chemical products can be produced simultaneously, the raw materials can be sufficiently utilized, the generation of waste materials is reduced, the production cost is reduced, and the technological process is safe and environment-friendly.

The invention discloses keto acid reductase, a gene, an engineering bacterium and application of the keto acid reductase in the synthesis of chiral aromatic 2-hydroxy acid. The keto acid reductase hasan amino acid sequence shown as in one of SEQ ID NO. 4, SEQ ID NO. 8 and SEQ ID NO. 10. The invention provides efficient keto acid reductase from Leuconostoc lactis; the efficient keto acid reductaseis capable of catalyzing broad-spectrum aromatic 2-keto acid, substrate loading capacity of a substrate of benzoylformic acid is increased from 100 mM to 400 mM. A single-bacterium dual-plasmid triple-enzyme series redox cascade system is established with the keto acid reductase, 2-hydroxy acid dehydrogenase and glucose dehydrogenase and is capable of catalyzing most racemic aromatic 2-hydroxy acid subjected to efficient deracemization to obtain chiral aromatic (R)-2-hydroxy acid, and both yield and e. e. value are greater than 99%; the system is finally applied to prepare optically pure (R)-2-chloromandelic acid by deracemization of 300 mM 2-chloromandelic acid, and the yield is up to 83.8 g / (L d).

The invention discloses vegetable oil polyurethane soft foam polyol, and a preparation method and an application thereof. The method comprises the following steps: (1) carrying out ring-opening reaction on epoxy vegetable oil, benzoyl formic acid, a basic catalyst and an inert solvent in a first microchannel reactor of a microchannel reaction device to obtain vegetable oil polyol; and (2) carryingout addition polymerization reaction on the vegetable oil polyol obtained in the step (1), epoxy propane and an inert solvent in a second microchannel reactor of the microchannel reaction device to obtain the vegetable oil polyurethane soft foam polyol. The obtained vegetable oil polyurethane soft foam polyol is novel in structure and can completely replace the traditional petrochemical polyol tobe applied to the preparation of polyurethane foam materials.

The invention discloses a novel methyl benzoylformate initiator and a preparation method thereof. The general formula of the novel methyl benzoylformate initiator is as shown by a compound (1), a compound (2), a compound (3) and a compound (4) in the specification, wherein the substituent group R1 is selected from hydrogen, aryl, C1-C12 linear (branched) alkyls or alkoxys, C3-C12 naphthenic bases, and C4-C12 naphthenic alkyls, R2 is selected from aryl, C1-C12 linear (branched) alkyls, C3-C12 naphthenic bases, and C4-C12 naphthenic alkyls, and the substituent groups R3 and R4 are selected from C1-C12 linear (branched) alkyls. The invention provides a reactive and water-soluble methyl benzoylformate free radical initiator for taking part in photo-polymerization in an olefinic unsaturated compound system, and meanwhile, aims at thoroughly solving the problems of volatilization and migration.