The invention discloses a high-temperature-resistant anti-pricking composition and a preparation method thereof. The high-temperature-resistant anti-pricking composition is prepared from the following raw materials: rosin, starch, eucommia ulmoides, gum, stearic acid, pine tar, mica powder, sulfur, zinc oxide, alumina, kaolin, bentonite, potato residues, borax, flint, spinel, feldspar, rutile titanium dioxide, kyanite powder, andalusite powder, zirconium oxide, cobalt oxide, brown corundum sand, phosphoric acid and rare earth oxide. The high-temperature-resistant anti-pricking composition has the advantages of being safe, non-toxic, fireproof, antifouling, flame-retardant, water-resistant, weather-resistant, high-temperature-resistant, high-strength, blending and compounding, copolymerizing and grafting, cross-linking and interpenetrating, anti-radiation, anti-corrosion, natural, environment-friendly and the like, and has good adaptability and biocompatibility to biological tissues.