103results about How to "Enhanced antibody" patented technology

The invention aims to provide a Muscovy duck parvovirus. The Muscovy duck parvovirus is a YBMDV strain, and is preserved in the China General Microbiological Culture Collection Center of the China Committee Of Culture Collection For Microorganisms in the Institute of Microbiology Chinese Academy of Science at the address of No. 3, No. 1 yard, Beichen west road, Chaoyang District, Beijing, on November 11th, 2013; the preservation number is CGMCC No. 8504. The Muscovy duck parvovirus screened by the invention has the characteristics of low toxicity and high immunogenicity; dead embryo and embryo liquid can be obtained by vaccinating the Muscovy duck parvovirus to a Muscovy duck embryo; virus liquid can be collected after grinding and freeze thawing; a vaccine is prepared by ultrafiltration concentration, formalin inactivation, the addition of an adjuvant, and mixing and emulsification; the Muscovy duck parvovirus can improve antibody of the Muscovy duck, ensure parent source antibody level of an offspring, and prevent green duck parvovirus infection caused by Muscovy duck parvovirus; the vaccine has the advantages of high efficiency and good safety.

The invention belongs to the technical field of cosmetics, and particularly relates to polypeptide repair liquid and a preparation method thereof. Various peptide type raw materials are used for compounding the polypeptide repair liquid, so that the polypeptide repair liquid is rich in powerful repair ingredients; and acetyl hexapeptide-8, palmitoyl tripeptide-3, copper tripeptide-1, acetyl tetrapeptide-5, palmitoyl tetrapeptide-7 and carnosine are in combined action and synergistic interaction to dissolve and repair damaged cells in human bodies and promote a microcirculatory system to eliminate decomposed fat, so that the problem of poor cell protein repair is solved, and the purpose of repair is achieved. In addition, raw materials are rich in sources, so that the production cost is reduced, and the product competitiveness can be increased.

The invention relates to a drug for treating hyperlipidemia and a preparation method thereof. The drug is prepared by the following pharmaceutical raw materials: ginkgo leaf, hawthorn leaf, cassia seed, turmeric root-tuber, Mongolian snakegourd root, danshen root, sanchi, oriental waterplantain rhizome and prepared tuber fleeceflower root. The preparation steps thereof are as follows: 1) the sanchi is taken and smashed into fine powder, the ginkgo leaf and the hawthorn leaf are additionally taken and smashed into coarse powder, the percolation is carried out, percolate is collected, the recovery of ethanol with the reduced pressure is carried out, then the dilution, the removal of pigments and the separation of a water layer are carried out, ethyl acetate is used for shaking extraction, and the ethyl acetate is recovered with the reduced pressure from extract liquid and concentrated till the ethyl acetate is dry; 2) the cassia seed, the turmeric root-tuber, the Mongolian snakegourd root, the danshen root, the oriental waterplantain rhizome and the prepared tuber fleeceflower root are taken, 80 percent ethanol is used for reflux for two times, filtrate is merged, and the ethanol is recovered and vacuum-concentrated to a clear paste with the relative density of 1.40 and the temperature of 50 DEG C; and 3) the various medicine residues after the ethanol extraction are merged, then water is added for carrying out three times of decoction, decocted liquid is merged and filtered, then the standing is carried out, supernatant fluid is taken and concentrated to a thick paste, an extract of the step 2 and the sanchi powder are further added for even mixing, the mixture is dried at the temperature of 60 DEG C and then ground to the fine powder with 100 meshes, and the packaging into capsules with 0.5g is finally carried out for preparation.

A conjugate molecule comprising an oligo- or polysaccharide covalently bound to a carrier and its use as potential vaccine against infection by S. Flexneri.

HCV E1E2 compositions comprising E1E2 antigens, submicron oil-in-water emulsions and / or immunostimulatory nucleic acid sequences are described. The compositions can be used in methods of stimulating an immune response in a vertebrate subject.

The present disclosure relates to a symmetric bispecific antibody of the class IgG4 comprising two heavy chains which each comprise a variable domain, CH1 domain and a hinge region, wherein in each heavy chain: the cysteine in the CH1 domain which forms an inter-chain disulphide bond with a cysteine in a light chain is substituted with another amino acid; and optionally one or more of the amino acids positioned in the upper hinge region is substituted with cysteine, wherein the constant region sequence of each heavy chain is similar or identical and the variable region in each heavy chain is different, formulations comprising the same, the use of each of the above in treatment and processes for preparing said antibodies and formulations.

HCV E1E2 compositions comprising E1E2 antigens, submicron oil-in-water emulsions and / or immunostimulatory nucleic acid sequences are described. The compositions can be used in methods of stimulating an immune response in a vertebrate subject.