The invention relates to a Ni-based alloy oil sleeve for a high-acidity deep well, which comprises the following components in percentage by mass: less than or equal to 0.02 percent of C, less than or equal to 0.03 percent of P, less than or equal to 0.03 percent of S, less than or equal to 0.5 percent of Si, less than or equal to 1.0 percent of Mn, 40 to 60 percent of Ni, 20 to 30 percent of Cr, 1 to 10 percent of Mo, 1 to 5 percent of W, 0 to 5 percent of Co, 0.1 to 3.0 percent of Cu, 0.01 to 0.5 percent of Al, less than or equal to 0.01 percent of O, less than or equal to 1.5 percent of Ti, and the balance of Fe and inevitable impurities. In the invention, the thermal extrusion processing performance and corrosion resisting performance of the alloy are effectively ensured by controlling the contents of the Al and O. The 90 to 140 ksi steel-grade Ni-based alloy oil sleeve meeting different well depth requirements of high-acidity oil fields and gas fields is manufactured by thermal extrusion, 1,050-1,150 DEG C of solution treatment and cold rolling of the smelted and forged blanks.