44 results about "Proteins metabolism" patented technology

The invention provides recombinant native and mutein forms of human follicle stimulating hormone beta subunit (FSH beta) with characteristic glycosylation patterns which are influential in the metabolic activity of the protein. The invention also provides recombinant mutant forms of the human alpha subunit common to FSH, LH, CG, and TSH, to obtain hormones which also have unique glycosylation patterns. Also provided are recombinant materials to produce these subunits separately or together to obtain complete heterodimeric hormones of regulated glycosylation pattern.

The invention relates to a clinical treatment low-protein food and relative production. Wherein, said method ads alpha modify amidon into wheat amidon, to prepare low-protein food. The invention can realize treatment effect, to support kidney disease patient.

The invention discloses a Chinese herbal medicinal additive for preparing a pigling feed and belongs to the field of Chinese herbal medicines. The formula of the Chinese herbal medicinal additive is designed according to physiological characteristics of piglings. The Chinese herbal medicinal additive is prepared by decoction of raw materials including Radix Astragali, fleece-flower root, acanthopanax, Radix Codonopsis, corydalis tuber, honeysuckle flower, radix bupleuri, Sophora flavescens, safflower, dryopteris crasirhitom nakai, orange peel, medicated leaven, haw, plantain herb and phellodendron. The Chinese herbal medicinal additive contains a plurality of effective active components, can be used to promote synthesis of ferrohemoglobin and serum protein of piglings, resist anaemia and improve protein metabolism, raise utilization efficiency of nutrients and content of cholesterol in serum and enhance regeneration capacity of body, and also has a good effect of promoting metabolism and the like of piglings.

The invention relates to a low-energy-diet (LED) having effect on the basal metabolic rate, the protein metabolism and / or the energy expenditure, such as a low-energy-diet comprising Carbohydrate: 70-120 g, Protein: 50-80 g, Fat: 5-20 g, including medium chain triglycerides, and Iron: 20-30 mg / d, wherein the carbohydrate source and / or the fat source may increase the energy expenditure.

The invention relates to a formulated foodstuff with special medical purposes for patients with hyperuricemia and gout and provides a granule or powder solid beverage formed by mixing both medicinal and edible plants and extract thereof and a nutrient supplement. The granule or powder solid beverage contains submicron powder of green papaya, banana peel extract, green tea extract, sweet potato vine extract, kudzu vine root extract, Poria cocos extract, lotus leaf extract, cape jasmine extract, haw extract, licorice extract, stevia rebaudiana extract, xylo oligosaccharide, dipotassium hydrogen phosphate, sodium bicarbonate, vitamin C and nicotinamide. The granule or powder solid beverage provided by the invention is mainly directed at the characteristic of purine metabolism disorders of patients with hyperuricemia and gout, improves the complex process of biochemical metabolism like protein metabolism, purine metabolism and lipid metabolism in the bodies of patients with hyperuricemia and gout in virtue of special physiological active substances and targeted micronutrients included in the granule or powder solid beverage, indirectly inhibits synthesis of uric acid, promotes acid discharging and maintains nutrition functions like acid-base balance of the body.

The invention belongs to the technical field of research and development of medical products and relates to a preparation method and application of a composite Chinese magnoliavine fruit preparation. The method comprises the following steps of: selecting 6 to 9 grams of high-quality Chinese magnoliavine fruit, 6 to 9 grams of boschniakia rossica, 3 to 6 grams of eucommia bark, 3 to 6 grams of acanthopanax root, 3 to 6 grams of ginseng, 3 to 6 grams of lucid ganoderma, 3 to 6 grams of astragalus, 3 to 6 grams of mushroom, 2 to 4 grams of Indian buead, 2 to 4 grams of agaric, 2 to 4 grams of yam, 2 to 4 grams of hawthorn and 2 to 4 grams of Chinese date; washing; performing microwave drying; smashing into 50-mesh powder; adding water for boiling and extracting for three times; combining extracting solution; filtering to obtain filtrate; condensing the filtrate into extract; uniformly mixing the extract, agar and starch in the ratio of 4:1:16; and pelletizing by using a 10-mesh sieve; drying; sieving by using a 14-mesh sieve so as to obtain the composite Chinese magnoliavine fruit preparation. A product has the effects of promoting the liver function and protein metabolism of fancy carp, and is beneficial to industrial production.

The invention belongs to the technical field of medical product research and development, and relates to a preparation method and application of a compound white paeony root preparation. The preparation method comprises the following steps of: selecting and washing 6 to 9 g of high-quality white paeony root, 4 to 6 g of lucid ganoderma, 4 to 6 g of astragalus mongholicus, 4 to 6 g of ginseng, 4 to 6 g of honeysuckle, 4 to 6 g of andrographis, 4 to 6 g of baical skullcap root, 4 to 6 g of acorus calamus, 4 to 6 g of isatis root, 2 to 4 g of rhubarb, 2 to 4 g of phellodendron, 2 to 4 g of dandelion, 2 to 4 g of sophora flavescens, 2 to 4 g of garlic and 2 to 4 g of liquorice root; drying by using microwave; crushing into 50-mesh powder; adding water, boiling and extracting for 3 times; combining extracting solution; filtering to obtain a filtrate; concentrating the filtrate into an extractum; mixing the extractum and starch in a ratio of 1:4; granulating by using a 10-mesh sieve; and drying and screening by using a 14-mesh sieve to obtain the compound white paeony root preparation. The product has the effects of promoting the liver function and the protein metabolism of fancy carps. The product contributes to industrial production.

The invention discloses an anti-aging beauty injection and a preparation method thereof, and relates to the technical field of medical cosmetology. The anti-aging beauty injection comprises the following components by mass: 18-25 parts of normal saline, 19-29 parts of collagen, 23-32 parts of hyaluronic acid, 7-11 parts of poly-L-lactic acid, 5-6 parts of glutathione, 2-3 parts of mannitol, and 1-3 parts of vitamin. The collagen and the hyaluronic acid are added to achieve a filling effect, and the normal saline is added to effectively improve the problem of short-time body fluid secretion insufficiency. The main effect of poly-L-lactic acid is to stimulate the body to autonomously generate collagen, and is matched with glutathione to activate multiple enzymes and promote metabolism of sugar, fat and protein, mannitol can improve osmotic pressure of plasma, vitamin can improve cell activity, cells are stimulated to absorb the injection from multiple aspects, and the problems that in the prior art, beauty injection is prone to gathering, uneven in absorption and poor in absorption effect, and consequently the injection position swells and the beauty effect is poor are solved.

A sugarless strengthening element chickpea powder relates to an accessory food made of chickpea and used for curing diabetes and other diseases. The chickpea is peeled, grinded into thick liquid, added with maltodextrin and accessories containing chromium, concentrated, sprayed and dried, and then the chick pea powder is made. The chickpea powder is applied to children who are growing and the elderly. The chickpea not only supplements chromium easily lacked in the growing phase and in old age but also supplements finer protein substrate. Many experiments find that chromium plays an obvious role in promoting growth and development and in enhancing protein metabolism of the children who do a large amount of sports in the growing phase, thus improving the effect of light weight. As for the elderly, the chickpea supplements chromium easily lacked when supplementing calcium and protein at the same time, and also provides a certain amount of medium-chain fatty acid which does not accumulates in the body, thus effectively preventing and regulating diabetes, hyperlipidemia, atherosclerosis, osteoporosis, low immunity and other diseases.

The invention discloses a method for preparing spiced beef by using a pulsed magnetic field, and belongs to the technical field of beef processing. According to the method, preparation pretreatment ofthe spiced beef is carried out by adopting a method of combining ultrasonic soaking and the pulsed magnetic field, wherein the ultrasonic soaking adopts a CaCl2 solution and a starch solution, Ca<2+>is a trigger agent for protein metabolism and a biological enzyme, so that protein can be promoted to be metabolized so as to be converted into amino acid, and therefore the nutritional ingredients and the taste of the beef can be conveniently improved, the freshness, the tenderness and the smoothness of the beef can be conveniently kept through the starch solution, the shearing force of the beefcan be conveniently reduced through the ultrasonic mechanical effect, the fragmentation of beef fibers can be facilitated through the ultrasonic cavitation effect, and the freshness and the tenderness of the beef are improved.

The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and / or vitamin B12 and, optionally, agents that impact heme protein metabolism.

The invention discloses a gene chip used for researching the action of an AD (Alzheimer Disease)-controlling medicament. An oligonucleotide gene probe array is fixed on the chip, wherein the oligonucleotide is an important biomolecule gene closely related to the occurrence and development process of the AD and relates to pathophysiological molecules, such as familial AD genes and susceptibility genes, amyloidosis, microtubule and cytoskeleton recombination, cynapse function, neurotransmission and ion channel, nerve regeneration, immunoregulation, immune response, signal transduction, chondriosome, protein metabolism, and the like. The chip of the invention can be used for researching pharmacological actions and action mechanisms of the AD-preventing and treating medicament containing a chemical medicament, a biotech drug, a single traditional Chinese medicine, a traditional Chinese medicine compound and an extract thereof, researching the sifting, the prescription, and the like of the AD-controlling medicament and researching the AD pathogenesis and carrying out auxiliary and differential diagnosis on a clinical case. The gene chip overcomes the defect of researching a multifactorial disease medicament by utilizing the method of a single target and has favorable application prospect.

The present invention discloses a piglet composite premix composition. The composition comprises the following raw materials, wherein the raw materials comprise, by mass: 0.04-0.05 parts of glycine zinc, 0.1-0.2 parts of ferrous fumarate, 0.01-0.015 parts of yeast selenium, 0.1-0.15 parts of ethoxyquin, 0.1-0.3 parts of yeast chromium, 0.05-0.1 parts of lysine zinc, 10-25 parts of calcium hydrogen phosphate, 40-60 parts of zeolite powder, and 10-20 parts of calcium carbonate. The 1 Kg of the prepared piglet composite premix composition further comprises: 240-300 IU of VE, 800-900 mg of VB2, 500-600 mg of VB12, and 350-400 mg of VB6. With adopting the piglet composite premix composition of the present invention in the feed ration, the appetite of the piglets can be enhanced, and the growthdevelopment and the tissue regeneration of the body can be promoted; with accelerating the glucose utilization in the body, the protein metabolism and the growth development are promoted so as to increase the feed intake, and completely digest, absorb and utilize the nutrient substances in the feed; with participating in the immune function, the immune mechanism is enhanced, the resistance is improved, and the external stress can be effectively resisted.

The invention discloses a medicine for resisting altitude stress and production equipment, and relates to the field of medicine for resisting altitude stress. The medicine for resisting altitude stress is prepared from the following components in parts by weight: 10-20 parts of rhodiola crenulata powder, 5-10 parts of dried ginger powder, 8-10 parts of tomato powder, 5-10 parts of soybean powder, 5-10 parts of brown powdered sugar, 10-15 parts of plum powder, 2-5 parts of coenzyme Q10, 1-2 parts of selenium, 3-5 parts of a vitamin mixture and 2-4 parts of amineral matter mixture. Selenium can activate main antioxidant enzyme-glutathione anti-peroxidase in cells, soybean meal and pea meal can increase protein intake, when people enter plateau areas, protein metabolism of organisms is enhanced, sufficient high-quality protein must be eaten, and by matching with the rhodiola crenulata powder for medicine preparation, the effect of the medicine for resisting altitude stress is improved; and meanwhile, the plum powder and the brown powdered sugar are added, the sweet taste is increased through the brown powdered sugar, the sour taste is increased through the plum powder, the taste of the medicine can be adjusted, the medicine is convenient to take, and large-scale application and popularization are facilitated.

The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and / or vitamin B12 and, optionally, agents that impact heme protein metabolism.

The invention relates to the field of food, in particular to an energy bar, a preparation method thereof and application of the energy bar in preparation of muscle injury resistant products. The energy bar is prepared from the following raw materials: cocoa butter replacer dark chocolate, isomaltooligosaccharide, highland barley protein, soybean protein, whey protein, quinoa, peach kernel, medium-chain triglyceride, casein, whole milk powder, glycerol and edible oil. The isomaltooligosacharide, MCT and other raw materials in the energy bar provided by the invention can ensure the rapid energysupply and slow energy supply effects of the product, and besides, proteins from different sources contained in the energy bar cooperate with each other, so that the protein metabolism requirements atdifferent exercise stages can be met as much as possible, muscle tissues of exercisers are repaired, and therefore, the energy bar disclosed by the invention can also be used for enhancing the satiety of the product.

The invention discloses high-protein black chocolate sauce. The high-protein black chocolate sauce comprises the following raw materials in parts by weight of 164-200 parts of medium-chain triglyceride, 180-240 parts of whey protein isolate powder, 40-70 parts of erythritol, 18-27 parts of low-fat cocoa powder, 6-12 parts of citrus fibers, 2-3 parts of phospholipid and 1-3 parts of bacillus coagulans. A preparation method of the high-protein black chocolate sauce comprises the following steps of taking half of the medium-chain triglyceride and the citrus fibers, performing uniform stirring byusing a high-speed shearing machine, adding the residual medium-chain triglyceride and the erythritol into an electric heating sauce boiling jacketed kettle, performing stirring, then sequentially adding the low-fat cocoa powder, the whey protein isolate powder, the phospholipid and the bacillus coagulans, performing uniform stirring, and performing homogenization for three times in a homogenizerto obtain the finished high-protein black chocolate sauce. The black chocolate sauce has the advantages that the black chocolate sauce is free of fat and beneficial to reduction of fat intake of users, and the whey protein powder is easy to absorb; digestion is promoted, immunity is enhanced and health of protein metabolism is promoted; and the melting point of the black chocolate sauce can be increased to 40 DEG C, so that modeling of desserts such as cakes is facilitated.

The invention discloses a traditional Chinese medicine composition applied to preparing medicines for curing diabetes cardiomyopathy. Tests prove that the pharmaceutical composition can enhance the activity of suckling mouse cardiac muscle cells in vitro culture; by promoting the expression of mRNA of superoxide dismutase (SOD2), free radicals are eliminated and high-glucose-induced myocardial cell injury is prevented by restraining oxidative stress; simultaneously, the medicinal composition can improve myocardial lesions of a diabetes rat model and restrain cardiac muscle cell apoptosis; gene chip test results show that the medicinal composition plays the roles of curing the diabetes cardiomyopathy in the aspects of correcting sugar and protein metabolism, enhancing antioxidant capacity, inhibiting cell apoptosis and the like; and the experimental results prompt that the medicinal composition can protect the cardiac muscle of a patient and cure the diabetes cardiomyopathy.

The identification of 101 genes upregulated or differentially expressed by mature human oocytes is provided herein. These genes and the corresponding gene products will facilitate a greater understanding of oogenesis, folliculogenesis, fertilization, and embryonic development. In addition these genes and the corresponding gene products can be used to effect dedifferentiation and / or transdifferentiation of desired somatic cells. The resultant dedifferentiated cells and somatic cells derived therefrom can be used in cell therapies such as in the treatment of cancer, autoimmunity, and other diseases wherein specific types of cells such as hematopoietic cells may be depleted because of the underlying disease or the treatment of the disease.Also, a core group of 66 transcripts was identified by intersecting significantly up-regulated genes of the human oocyte with those from the mouse oocyte and from human and mouse embryonic stem cells. Within the up-regulated probe sets, the top overrepresented categories were related to RNA and protein metabolism, followed by DNA metabolism and chromatin modification. This invention therefore provides a comprehensive expression baseline of genes expressed in in vivo matured human oocytes. Further understanding of the biological role of these genes will also expand knowledge on meiotic cell cycle, fertilization, chromatin remodeling, lineage commitment, pluripotency, tissue regeneration, and morphogenesis.

The invention discloses a high-yield leucine p-nitroanilide production lactobacillus helveticus strain and application thereof and belongs to the field of microbial technology. The high-yield leucinep-nitroanilide production lactobacillus helveticus strain, namely lactobacillus helveticus CCFM1035, has the advantages of being high in growth and production speed as well as high in yield of leucinep-nitroanilide (Lys-pNA), and can effectively enhance the protein metabolism of fermented foods, reduce bitter taste of the fermented foods and improve the flavor of the fermented foods, thereby highin application significance to prepared foods such as acidified milk, acidified milk beverages, cheese, Koumiss, sour cream, cookies, vinegar and soybean sauce.

The invention discloses a method for preparing hotpot condiment grease rich in medium and long carbon chain triglyceride by an enzyme method, which comprises the following steps: taking medium and long carbon chain triglyceride as raw materials, adding expanded lipase into a solvent system, and reacting to obtain the hotpot condiment grease. Vegetable oil is selected as a raw material, the price of the vegetable oil is lower than that of beef tallow, the vegetable oil does not contain cholesterol and trans-fatty acid and is healthier than the beef tallow, and the obtained product is rich in medium and long carbon chain triglyceride and has positive effects in the aspects of weakening protein metabolism, promoting nitrogen balance, enhancing the immune function, reducing cancer risks and the like.

The invention belongs to the technical field of research and development of medical products. The invention relates to a preparation method and application of a compound radix bupleuri preparation. The preparation method comprises the following steps: selecting 4-6g of high-quality radix bupleuri, 4-6g of medlar, 4-6g of spirulina, 4-6g of mushroom, 4-6g of kelp, 4-6g of cordate houttuyniae, 4-6g of ginseng, 2-3g of star anise, 2-3g of ginger, 2-3g of garlic, 2-3g of hawthorn, 2-3g of Chinese date and 9-12g of shrimp meal, washing, carrying out microwave drying, and grinding into 50-mesh powder; adding water to the powder, boiling to extract three times, merging the extracting solutions, and filtering to obtain the filtrate; and concentrating the filtrate into extract, uniformly mixing the extract and starch at a ratio of 1:4, granulating with a 10-mesh sieve, drying, and then sieving with a 14-mesh sieve, thus obtaining the compound radix bupleuri preparation. The product has the function of promoting liver functions and protein metabolism of golden carps and is beneficial to industrial production.

A sugarless strengthening element chickpea powder relates to an accessory food made of chickpea and used for curing diabetes and other diseases. The chickpea is peeled, grinded into thick liquid, added with maltodextrin and accessories containing chromium, concentrated, sprayed and dried, and then the chick pea powder is made. The chickpea powder is applied to children who are growing and the elderly. The chickpea not only supplements chromium easily lacked in the growing phase and in old age but also supplements finer protein substrate. Many experiments find that chromium plays an obvious role in promoting growth and development and in enhancing protein metabolism of the children who do a large amount of sports in the growing phase, thus improving the effect of light weight. As for the elderly, the chickpea supplements chromium easily lacked when supplementing calcium and protein at the same time, and also provides a certain amount of medium-chain fatty acid which does not accumulates in the body, thus effectively preventing and regulating diabetes, hyperlipidemia, atherosclerosis, osteoporosis, low immunity and other diseases.

The invention discloses a high efficiency feed for meat ducks, for assisting to promote the absorption and the utilization of zinc of meat ducks by phytase. The high efficiency feed comprises the following components in parts by weight: phytase, chitosan anion liquid, amino acid chelated zinc, wheat bran, fly larva powder, cactus dry powder, garlic dry powder, maifan stones, threonine, ethoxyquin, water-soluble modified xanthophyll and the like. According to the high efficiency feed disclosed by the invention, the wheat bran, the fly larva powder and the like are adopted as main materials so as to prepare the feed for the meat ducks. The high efficiency feed provides plant protein and animal protein and nutrient components capable of improving immunity, sterilization and disinfection. The phytase is adopted for assisting the chitosan cation liquid, the amino acid chelated zinc and shiraia bambusicola alkone so as to prepare maifan stone powder carried and loaded chitosan modified organic zinc to be used as a whole, the absorption and the utilization of phosphorus in plant sources by the ducks are promoted, besides, the absorption and the utilization of the organic zinc are also promoted, and the transformation of the organic zinc in bodies is also promoted, so that the organic zinc can participate in the processes of synthesization of enzymes in organisms of the ducks, protein metabolism and the like. Auxiliary materials, such as threonine are adopted, so that the growth of the ducks is promoted in various degrees, and the high efficiency breeding of the ducks is promoted.

The invention discloses a chromium-rich organic nutrient solution, which is prepared from the following raw materials in parts by weight: 10 to 15 parts of ferrous sulfate, 20 to 35 parts of trivalent chromium passivation solution, 2 to 3.5 parts of antibacterial agent, 5 to 7 parts of organic chromium, 3 to 4.5 parts of boric acid powder, 2 to 3.5 parts of inorganic salt, 10 to 15 parts of nutritional agent and 15 to 20 parts of water. A preparation method of thechromium-rich organic nutrient solution comprises the steps of 1, pouring the trivalent chromium passivation solution, the antibacterial agent, the nutritional agent, the organic chromium and the water into a material injection tank corresponding to the material mixing equipment. The content of chromium in crops is increased through the organic chromium, when a user eats the crops rich in chromium, the content of the necessary trace element chromium in a human body is increased, good effects of reducing blood sugar and blood fat are achieved for the user, meanwhile, metabolism of sugar, lipid and protein of the human body can be adjusted, and by adding the organic chromium into the nutrient solution, a chromium-rich organic nutrient solution is generated, the chromium content of crops can be effectively increased, and the use effect of the chromium-rich organic nutrient solution is improved.

The invention discloses a culture medium for promoting germination of bletilla striata and a preparation method thereof, and the preparation method comprises the following steps: step 1, slowly adding a culture matrix, an organic solution, a macroelement base solution and a growth-promoting substrate into sterile water, heating to 40-50 DEG C, and continuously stirring until the materials are completely and uniformly dissolved; 2, the dissolved substance is cooled, high-temperature sterilization is carried out, and the culture medium is obtained.The organic liquid is a compound of vitamin, glycine, inositol and coconut milk, the vitamin is prepared by compounding pyridoxine hydrochloride and nicotinic acid, and the vitamin and the glycine are added into the coconut milk; the bletilla striata extract can effectively participate in vital activities of protein metabolism, fat metabolism and sugar metabolism of cell tissues in a coenzyme form, and is matched with inositol to participate in carbohydrate metabolism and ion balance, so that the growth of bletilla striata tissues and the formation of embryoid and buds are effectively promoted.

The invention discloses a strain of Lactobacillus helveticus with high production of lysine aminopeptidase and application thereof, belonging to the technical field of microorganisms. The Lactobacillus helveticus CCFM1035 has the advantages of fast growth rate, fast acid production and high yield of lysine aminopeptidase (Lys-pNA), which can effectively enhance the protein metabolism in fermented foods and reduce the bitterness of fermented foods It has important applications in the preparation of fermented milk, fermented milk drinks, cheese, kumiss, kumiss, sour cream, cookies, vinegar or soy sauce and other fermented foods .

Provided herein are methods, systems, and kits for improving success rates in assisted reproductive technologies such as in vitro fertilization, frozen embryo transfer, and intrauterine insemination. These methods, systems, and kits rely on levels of protein, metabolite, and microRNA markers determined herein to be linked to uterine toxicity and embryo implantation failure.

The invention discloses an application of bioactive peptides extracted from human hair in the preparation of a therapeutic drug for improving protein metabolism of chronic kidney diseases, and a drug. The human hair extracted BAPs can effectively improve the indexes of serum albumin (Alb), prealbumin (PAb) and transferrin (TRF) of CKD patients, improves the symptoms of protein metabolism disorder caused by renal dysfunction, avoids adverse consequences caused by malnutrition of CKD patients, and delays the progress of CKD to a certain extent.