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56 results about "Shiraia bambusicola" patented technology

Shiraia bambusicola is a parasitic fungus on twigs of several genera of bamboos, and its relatively large stromata are used in traditional Chinese medicine. It is the sole species in the monotypic genus Shiraia. It is widely distributed in many provinces of Southern China and also in Japan.

Method for synchronously producing hypocrellin and shiraia bambusicola polysaccharides

The invention relates to the field of bio-fermentation, in particular to a method of producing hypocrellin pigments and polysaccharides simultaneously with solution fermentation. In the art of producing hypocrellin pigments and polysaccharides simultaneously with solution fermentation of the invention, bottle-shaking culture is firstly proceeded, convolution culture is the second step, the enlarging culture of the shaking bottle is the third step and fermentation culture is the final step. In the step of bottle-shaking culture, strain of the hypocrellin is utilized as parent strain, bacteria on the inclined surface of the tube are introduced to a shaking bottle inside which liquid medium is arranged, and the charging coefficient of the shaking bottle is 0.1 to 0.25. In the step of convolution culture, the rotation speed of the convolution culture is 150 to 250 turnings every minute and the culture temperature is 22 to 27 DEG C. In the third step of enlarging culture of the shaking bottle, the culture material achieved by the bottle-shaking culture is shifted to the culture medium of the enlarging culture of the shaking bottle to proceed culture, the inoculation amount is 2-10%, the rotation speed of a rotation bed is 150-250 turnings every minute, the culture temperature is 22 to 27 DEG C, and the culture period is 72 to 120 hours. In the final step of fermentation culture, the culture material achieved by the enlarging culture of the shaking bottle is transferred to a fermentation pot inside which fermentation culture medium is installed to be cultured, the inoculation amount is 5-10%, and the culture temperature is 22 to 27 DEG C. The hypocrellin fermentation liquid is achieved after the fermentation is finished, and the hypocrellin pigments and polysaccharides are respectively achieved by separating and purifying the achieved fermentation liquid.
Owner:WENZHOU UNIVERSITY

Method for preparing perylenequinone pigment under catalysis of Shiraia bambusicola

The invention discloses a method for preparing a perylenequinone pigment under the catalysis of Shiraia bambusicola and belongs to the technical field of bioengineering. In the method, naphthoquinone, cinnamic acid and the like which form a substrate are used to prepare the perylenequinone pigment under the catalysis of the Shiraia bambusicola. The catalytic process is implemented by: A), adding the substrate into culture system in a cell liquid culture process, wherein the perylenequinone pigment yield is up to 2.9g / L and the transformation rate is up to 9.7 percent; or B), placing cells obtained by liquid fermentation culture in a reaction system having the substrate, wherein the perylenequinone pigment yield is up to 35.3g / L and the transformation rate is up to 39.7 percent; or C), adding the substrate into a culture system in a cell solid culture process, wherein the perylenequinone pigment yield is up to 1.5g / 100g and the transformation rate is up to 46 percent. The method adopts a perylenequinone pigment-producing Shiraia bambusicola strain and specific substrate transformation to produce hypocrellin, is high in transformation rate, low in cost, less in step and applicable to industrial production and has excellent industrial application prospect.
Owner:江苏竹红生物科技有限公司

Method for improving hypocrellin yield in shiraia bambusicola

The invention discloses a technology for improving hypocrellin yield in shiraia bambusicola by using a polystyrene type nonpolar adsorption resin, wherein the technology comprises: carrying out activating culture for a strain, carrying out liquid seed culture, and carrying out co-culture fermentation for the strain and the adsorption resin. The method is characterized in that: with the co-culture fermentation, the resin can absorb the hypocrellin secreted by the shiraia bambusicola, and the hypocrellin content in the shiraia bambusicola can be improved so as to improve the hypocrellin yield. Therefore, with the present invention, the synthesis of the hypocrellin in the shiraia bambusicola can be effectively stimulated, the hypocrellin production in the culture system can be improved, the yield is high, the cost is low, the steps are simple, and the method can be used for the industrial production, and has a good industrial application prospect.
Owner:SUZHOU UNIV

Deer blood wine for treating rheumatism and gout and preparation method thereof

The invention discloses a deer blood wine for treating rheumatism and gout and a preparation method thereof, wherein the deer blood wine comprises the following raw materials in parts by weight: 20-30 parts of deer blood, 10-15 parts of aspongopus, 15-20 parts of scorpion, 8-12 parts of ant, 15-25 parts of ptyas dhumnades, 10-15 parts of pangolin, 5-10 parts of cibotium rhizome, 15-20 parts of jujube peel, 8-12 parts of muscardine silkworm, 20-30 parts of eucommia, 15-25 parts of taxillus, 12-16 parts of achyranthes bidentata, 9-14 parts of fibraurea recisa, 18-24 parts of vegetable sponge of luffa, 10-15 parts of seatung bark, 20-25 parts of phellodendron, 15-20 parts of rhizoma atractylodis, 16-22 parts of fructus liquidambaris, 10-15 parts of Chinese parsnip root, 8-12 parts of peony vine, 20-30 parts of campsis grandiflora loisel, 15-25 parts of fish poison yam rhizome, 14-18 parts of shiraia bambusicola, 10-15 parts of botrychiam ternatum and 400-500 parts of wine of 50 DEG to 60 DEG. The deer blood wine in the invention has effects of clearing heat and removing toxicity, promoting flow of qi and blood circulation, inducing menstruation to relieve menalgia and dispelling wind and eliminating dampness. The deer blood wine has a good curative effect in the treatment of gout, rheumatoid arthritis, rheumatoid arthritis, numbness of limbs, traumatic injury, lumbar and leg ache and other symptoms.
Owner:张兴保

Bis(p-benzoquinone) compound and extraction method thereof

The invention discloses a bis(p-benzoquinone) compound and an extraction method thereof. The bis(p-benzoquinone) compound is named as 2,7-dihydroxy-3,6,9-trimethyl-9H-xanthene-1,4,5,8-tetraone. The bis(p-benzoquinone) compound with the molecular weight being 316 and unsaturation degree being 11 can form orange red needle crystals in an ethyl acetate solution, is represented as a molecular formula of C16H12O7 and is represented as a structural formula containing one oxygen heterocycle, two hydroxys, three methyls and four ketone groups. The extraction method of the bis(p-benzoquinone) compound includes isolating a haematochrome-producing hypha fermentation solid from a fruiting body of Shiraia bambusicola Henn., extracting through ethyl acetate to obtain extract, adding the extract into petroleum ether for sufficient dissolving, centrifuging to remove a supernatant, subjecting a precipitate to ethyl acetate dissolving and then column chromatography on silica gel, concentrating to crystallize and using reversed-phase high performance liquid chromatography for detecting purity so as to obtain the novel high-purity compound. The bis(p-benzoquinone) compound has a high free radial scavenging capability and provides a lead compound resource for developing new drugs as a natural product of a novel structure.
Owner:NANJING NORMAL UNIVERSITY

Traditional Chinese medicinal preparation for treating dysthymia

The invention provides a traditional Chinese medicinal preparation for treating dysthymia. The traditional Chinese medicinal preparation is prepared from the following traditional Chinese medicinal materials: fossil fragments, rose flowers, shiraia bambusicola, rhizoma nardostachyos, concha haliotidis, herba epimedii, peach kernels, rhizoma polygonati, radix salviae miltiorrhizae, antelope's horn, pinellia ternata, radix bupleuri, Chinese yam, saffron crocus, albizia flowers, polygala tenuifolia, lotus seeds, the fruits of Chinese wolfberry, rhizoma gastrodiae, the root of bidentate achyranthes, prepared rehmannia root, rhizoma anemarrhenae, cinnabar, oyster, mint and spina date seeds. The traditional Chinese medicinal preparation has good clinical effects for patients suffering from depressive disorder at various stages, and has good treatment effects at the medication initial stage, the symptoms including insomnia, early awakening, dreaming and agriothymia are alleviated, the pain of the patient is greatly reduced, and the traditional Chinese medicinal preparation has the outstanding effect of being free of toxic and side effects, can rapidly improve the disease symptoms of the patients, has the advantages of significant curative effects and small possibility of relapse, and is low in treatment cost.
Owner:侯霞

Preparation method for medicine for treating renal failure

A medicament for treatment of renal failure and a preparation method therefor. Shiraia bambusicola, Fossilia ossis Mastodi, Angelica pubescens, dried tangerine peel, Hedyotis diffusa, Gynostemma pentaphyllum, and Bauhinia championii seed are used as active ingredients, while Lophatherum gracile, Glycyrrhiza uralensis, smoked Prunus mume seed, Pseudostellaria heterophylla, Pueraria lobata Ohwi、lotus leaf, Citrus medica var. sarcodactylis, Leonurus Artemisia, Andrographis paniculata, Gardenia jasminoides, Bambusae Caulis in Taeniam, papaya, and processed Rehmannia glutinosa are used as excipients. With the traditional Chinese medicine principles that kidneys are the congenital foundation and that kidneys rule water, kidney vital energy is cultivated and kidney fluids are regulated for differentiation and treatment of renal failure. Side effects are mitigated, great efficacy is provided, and patient suffering is alleviated.
Owner:WEIFANG MODERN RHEUMATOLOGY RES INST

Drug for treating rheumatism and rheumatoid and preparation method thereof

The invention provides a drug for treating rheumatism and rheumatoid and a preparation method thereof. The drug is prepared according to the following steps of: combining 14 Chinese herbal medicines including cooked radix aconiti carmichaeli, herba asari, ramulus cinnamomi, radix aconite lateralis preparata, rhizoma zingiberis, shiraia bambusicola P.Henn, radix achyranthis bidentatae, siegesbeckia orientalis, ramulus mori, common threewingnut root, scarabaeoidea larva, sulfur, pangolin scales and dried and cooked strychnospierriana with three western medicines including vitamin B1 tablets, metoclopramide tablets and diclofenac sodium tables; and grinding or decocting with water and extracting to form paste, and adding conventional auxiliary materials to prepare different preparations. The drug combines traditional herbal medicines and western medicines, is scientific and particular in formula as well as simple and reasonable in preparation method and has the advantages of both traditional herbal medicines and western medicines; side effects are relatively less, and the curative effects supplement and complement each another; and the drug has a quick effect and a lasting medicinal effect and can effectively treat and relive rheumatism and rheumatoid.
Owner:广西东兴市创新特色医药科技发展有限公司

Formula and preparation process of medium for culturing medical shiraia bambusicola henn

The invention discloses a formula and a preparation process of a medium for culturing medical shiraia bambusicola henn and belongs to the technical field of processing of mediums. The formula is characterized in that the medium contains 21 to 37 percent of nutrient solution, 8 to 19 percent of sugar, 2 to 11 percent of fungus, 5 to 16 percent of synergistic component and 30 to 56 percent of mineral water. According to the formula and the preparation process of the medium for culturing the medical shiraia bambusicola henn, the medium contains various nutritional components which are required by the survival of shiraia bambusicola henn, the nutrients required by growth of shiraia bambusicola henn can be provided, the culture period can be shortened, the yield and the quality of hypocrellin can be improved, the medium is good in culture effect, the quality of the cultured hypocrellin does not have obvious difference with that of the shiraia bambusicola henn hypocrellin in nature, and the medium is easy and convenient to prepare, safe and effective, convenient to use, and low in production cost. The formula of the medium can be applied to artificial culturing of shiraia bambusicola henn hypocrellin in a laboratory and industrial large-area production and development of shiraia bambusicola henn hypocrellin.
Owner:ZHEJIANG FORESTRY UNIVERSITY

Shiraia bambusicola with high yield of hypocrellin, and cultivation method and application of Shiraia bambusicola

ActiveCN111218407AImproving the Ability to Produce Hypocretin with High EfficiencyIncrease productionFungiMicroorganism based processesBiotechnologyMicroorganism
The invention belongs to the technical field of microbial fermentation, and particularly relates to Shiraia bambusicola with high yield of hypocrellin, and a cultivation method and application of theShiraia bambusicola. The Shiraia bambusicola with high yield of hypocrellin is preserved in the China General Microbiological Culture Collection Center with the classification name of Shiraia bambusicola, and the preservation number is CGMCC No.18808. The Shiraia bambusicola can be fermented to obtain high-yield hypocrellin, the total amount of hypocrellin can reach 4762.9mg / 100g, and the obtainedhypocrellin includes hypocrellin A, hypocrellin B, hypocrellin C and hypocrellin D at the same time.
Owner:JINAN GUOLI BIOLOGICAL SCI & TECH +1

Stomach nourishing traditional Chinese medicine composition

The invention discloses a stomach nourishing traditional Chinese medicine composition. The stomach nourishing traditional Chinese medicine composition comprises 2-3 parts of eleocharis dulcis, 1-3 parts of white honey, 1-2 parts of rhizoma corydalis, 1-2 parts of shiraia bambusicola henn, 3-5 parts of herba pogostemonis, 1-3 parts of trapa incisa, 2-4 parts of capsella bursa-pastoris roots, 3-5 parts of physalis alkekengi, 1-2 parts of peanut coats, 1-2 parts of santonin, 3-5 parts of royal jelly freeze-dried powder, 1-2 parts of herba gendarussae, 1-3 parts of folium pyrrosiae, 2-3 parts of rumex patientia roots, 3-5 parts of poria and 1-2 parts of liquidambar formosana hance resin. Owing to the mode, the stomach nourishing traditional Chinese medicine composition has the advantages that excellent stomach nourishing effects can be realized by the stomach nourishing traditional Chinese medicine composition, the stomach nourishing traditional Chinese medicine composition is free of side effects, and appetite can be improved.
Owner:武志云

A kind of deer blood wine for treating rheumatism and gout and its preparation method

The invention discloses a deer blood wine for treating rheumatism and gout and a preparation method thereof, wherein the deer blood wine comprises the following raw materials in parts by weight: 20-30 parts of deer blood, 10-15 parts of aspongopus, 15-20 parts of scorpion, 8-12 parts of ant, 15-25 parts of ptyas dhumnades, 10-15 parts of pangolin, 5-10 parts of cibotium rhizome, 15-20 parts of jujube peel, 8-12 parts of muscardine silkworm, 20-30 parts of eucommia, 15-25 parts of taxillus, 12-16 parts of achyranthes bidentata, 9-14 parts of fibraurea recisa, 18-24 parts of vegetable sponge of luffa, 10-15 parts of seatung bark, 20-25 parts of phellodendron, 15-20 parts of rhizoma atractylodis, 16-22 parts of fructus liquidambaris, 10-15 parts of Chinese parsnip root, 8-12 parts of peony vine, 20-30 parts of campsis grandiflora loisel, 15-25 parts of fish poison yam rhizome, 14-18 parts of shiraia bambusicola, 10-15 parts of botrychiam ternatum and 400-500 parts of wine of 50 DEG to 60 DEG. The deer blood wine in the invention has effects of clearing heat and removing toxicity, promoting flow of qi and blood circulation, inducing menstruation to relieve menalgia and dispelling wind and eliminating dampness. The deer blood wine has a good curative effect in the treatment of gout, rheumatoid arthritis, rheumatoid arthritis, numbness of limbs, traumatic injury, lumbar and leg ache and other symptoms.
Owner:张兴保
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