155 results about "M-Cresol" patented technology

A dual catalyst system thermoplastic phenolic resin preparation method comprises the steps of proportioning, refluxing and reacting, and drying; the raw materials comprises phenol or m-cresol and aldehydes compound, water, organic acid or inorganic acid and bivalent acetate in a molar ratio of 1:0.5-0.9:0-3.0:0.001-0.040:0.001-0.020; wherein, acetate is used as first catalyst and organic acid or inorganic acid is used as second catalyst in reaction process. The invention adopts phenolic aldehyde addition-condensation reaction in dual catalyst system to prepare the thermoplastic phenolic resin; the method has the advantage of rapid polymerization rate, high yield and low content of free phenols; the thermoplastic phenolic resin can be applied for preparing the coated sand and the prepared coated sand has higher hot tensile strength and tensile strength at room temperature.

The invention discloses a preparation method for tazobactam. The preparation method comprises the following steps: with benzhydryl s-oxopenicillanate as a raw material, successively carrying out thermal cracking, bromination, catalytic oxidation and a reaction with 1H-1,2,3-triazole under the action of an anion resin carrier so as to obtain an important intermediate 2beta-(1H-1,2,3-triazolyl)-2alpha-methyl-benzhydryl penicillanate-1beta-oxide; and carrying out potassium permanganate oxidation and then protective group removal under the action of meta-cresol so as to obtain the target product tazobactam. The invention is characterized in that a sulfur atom is subjected to monooxidation so as to improve compound stability, then a nucleophilic substitution reaction with 1H-1,2,3-triazole is carried out so as to effectively control the possibility of ring enlargement during introduction of a triazole ring, and total yield is increased to 68%. The preparation method has the advantages of stable process, simple and convenient operation, easy separation and purification of the reaction product, a small amount of waste gas, waste water and industrial residues, high yield and suitability for clean, industrial and large-scale production.

The invention relates to a method for synthesizing the emodic acid which is the essential component of the traditional Chinese medicine rhubarb horsetails and duroruiyin which is antipyretic analgesic and osteoarthritis treating medicine, employing 3-nitro-ortho-phthalic anhydride as start raw material, reacting with m-cresol fuke, through reaction of reduction, diazonium salt, ring-combining to prepare intermediate compound chrysophanol, oxygenating to emodic acid, preparing duroruiyin through acetylation, the total productivity of the six reaction is 31.1%, the process is optimize through pilot-scale experiment a nd suitable for industrial production.

The invention discloses a high performance liquid chromatography determination method for volatile phenolic compounds in white spirits. By adopting a high performance liquid chromatogram-fluorescence detector (HPLC-FLD) technique to analyze volatile phenolic compounds in white spirits, the method of the invention, when used in analysis of volatile phenolic materials, can determine the following 10 volatile phenolic compounds of phenol, guaiacol, p-cresol, m-cresol, o-cresol, 4-methylguaiacol, 4-vinylphenol, 4-ethylphenol, 4-vinylguaiacol and 4-ethylguaiacol in white spirits. And the method has the advantages of no need for derivatization, high accuracy, high sensitivity and good repeatability.

The invention discloses a process method for separating and purifying cresol mixed isomers. The process method is characterized by comprising the following steps: inputting a mixture primarily comprising m-cresol and p-cresol isomers into a sequential simulated moving bed as a feed to be adsorbed and separated, obtaining a high purity p-cresol solution from a displacing liquid port, and then rectifying, separating and removing a desorption solvent to obtain a m-cresol product; and obtaining a mixed solution primarily comprising m-cresol from a raffinate port, then rectifying, separating and removing the desorption solvent to obtain a mixture rich in m-cresol, and then carrying out crystallization and separation to obtain the m-cresol product. The sequential simulated moving bed disclosed by the invention at least contains four chromatographic columns, a raw material feed inlet, a strippant feed inlet, a strippant discharge port and a raffinate discharge port. The process method can obtain high purity m-cresol and p-cresol products continuously and efficiently at the same time, and has a very good industrial application prospect.

The invention discloses a fashi citric acid rod Citrobacter farmeri SC01 and the application. The bacterium is obtained by artificial accumulation culture and separation cleansing from phenols cyanogen waste water treatment station one level aerobic pool sludge. The bacterium is preserved in china typical culture entreasure center of Wuhan University on January 7th 2008 year whose short form is CCTCC and preserving identification serial number is CCTCC NO: M208004. The fashi citric acid rod Citrobacter farmeri SC01 incorporating the invention can degrade phenyl hydrate, 2-methylphenol, m-cresol, 1-naphthyl hydroxide, 696mg/L m-cresol in 114 hours on aerobic condition, and the average degrading rate of speed ran up to 8.94mg/(L h) and the bacterium is sensitive to acheomycin, chloramphenicol, rifampicin and streptomycin, and the bacterium can be used safe and wide in harnessing and repairing wasted water and soil phenols pollution because the bacterium can not carryover drug-resistance factor spreading in aborigines bacterium when the bacterium is released into environment.

The invention discloses a phenolic aldehyde modified amine curing agent which is prepared by polycondensing mixed phenol, polyformaldehyde and mixed amine through Mannich reaction. The preparation method comprises the following steps: adding phenol, nonylphenol and m-cresol at 35-45 DEG C, and evenly mixing; sequentially adding hexamethylene diamine and triethylene tetramine, and adding polyformaldehyde for reaction in batches in the process of gradually heating to 70-80 DEG C; and after the addition of the polyformaldehyde is finished, further reacting at 70-80 DEG C to obtain the product after the reaction is finished. The curing agent can be directly cured in water, has certain toughness and is favorable in curing effect; an epoxy resin cured by the curing agent has high dry shear bonding strength and in-water cured shear bonding strength; and the preparation method of the curing agent is simple to operate and mild in reaction conditions, and industrial production can be realized.

The invention relates to a separation and purification method of m-cresol. The separation and purification method comprises the following steps: a) complexing: adding mixed cresol, urea and a mixed solvent formed by toluene and liquid alkane into a reactor, stirring, heating to increase the temperature to 65-90 DEG C, performing heat preservation for 1-2h, reducing the temperature to 40-60 DEG C, then cooling and crystallizing at the temperature of 0-20 DEG C for 1-2h, and filtering to obtain a complex solid and filtrate A; and b) decomplexing: adding the complex solid obtained in the step a) into an ether type solvent, stirring at the temperature of 10-60 DEG C, performing decomplexing reaction for 0.5-3h, and filtering to obtain urea and filtrate B; and performing decompression rectification on the filtrate B to obtain m-cresol. The method for separating m-cresol from mixed cresol is high in product purity, simple in process, low in solvent consumption, high in recovery rate and low in energy consumption and can operate at normal pressure, prevent the production of three wastes in a separation process and realize recycling of resources, so that the method is environment-friendly.

This invention relates to a method for treating salt-containing waste-water from the production of M-cresol. The waste-water, after pre-treatment of absorption by powder activated carbon, is proceeded the electroosmosis treatment. The effluent is used as sulphuric acid solution for cyclic utilization, the residual salt-containing waste-water is neutralized for production of mirabilite. In this invention, the recovered sulphuric acid solution, after the treatment, contains Naf ion with its concentration being lower than 2g/L, the sulphuric acid solution recovery rate is upto 80%, and being able to be utilized in hydrolytic reaction for M-cresol production. This method is useful for environmental protection.

The invention discloses a method for producing resordinol through direct hydrolysis. The method comprises the following steps: adding sulphuric acid or hydrochloric acid with certain concentration and meta-toluidine respectively according to a proportion into a blending pot so as to form meta-toluidine sulphate or meta-toluidine hydrochloride; sending the meta-toluidine sulphate or meta-toluidine hydrochloride aqueous solution from the blending pot into a high-pressure kettle; controlling the reaction temperature; carrying out the hydrolysis of the meta-toluidine sulphate or the meta-toluidine hydrochloride; recovering part of water in the hydrolysate through flash evaporation for blending; neutralizing the hydrolysate through ammonia spirit or caustic alkali aqueous solution till reaching a PH value of 3 to 5; carrying out organic extraction on the hydrolysate; and then recovering the extractant and refining coarse resordinol. The method adopts only one-step hydrolysis, thereby greatly reducing the dosage of sulphuric acid, and not using sodium nitrite. The concentration of the dilute sulfuric acid generated in the reaction process is lower than 2 percent. The method has the advantages that the cost of neutralizing the dilute acid is low, and the environmental pollution is also low.

The invention provides an improved synthesis method for diacerein, comprising taking 3-nitrophthalic anhydride as the raw material, carrying out a Friedel-Crafts reaction with m-cresol, deoxidizing, cyclizing and diazotizing to obtain an intermediate chrysophanol, then acetylating, and oxidizing to obtain high-purity diacerein with a total yield of 33.7%.

The invention relates to a fluidization catalytic method for producing m-cresol and p-cresol through isomerization of o-cresol. According to the method, o-cresol and a carrier gas are gasified in a preheater, and m-cresol and p-cresol are produced through isomerization by adopting the fluidization catalytic method, so that problems of short service life of a catalyst and low conversion rate in the isomerization process of cresol at present are better solved. The fluidization catalytic method can be applied to industrial production for large-scale production of the m-cresol and the p-cresol.

The invention discloses a novel synthetic process of thymol. The novel synthetic process is as follows: in the presence of a catalyst which is a composition of concentrated sulfuric acid and aluminum trichloride, a composition of polyphosphoric acid and aluminum chloride, a composition of concentrated sulfuric acid and zinc chloride or a composition of the polyphosphoric acid and the zinc chloride, continuously introducing a propylene gas in a reaction system containing m-cresol by controlling the reaction temperature to carry out isopropylation reaction of the m-cresol, so that the thymol with content of 98%-99.5% and yield of 75%-80% is finally prepared. And moreover, the novel synthetic process is low in cost, simple in process condition and easy to operate.

A preparation technical of m-cresol is that: M-cresol is diazotizated, and hydrolyzed while at the same time steam is distilled to prepare a distilled m-cresol hydrolysis liquid. The distilled hydrolysis liquid passes through a N3520 type macroporous resin, and is eluded by organic solvent; the m-cresol product is obtained after rectifying. The invention adopts steam to distil m-cresol generated by hydrolyzation in time, which produces little byproduct tarry matter and increases the yield rate of m-cresol; preparation of product and treatment of waste water are carried out at the same time, which reduces the waste water treatment procedure and simplify the progress of preparation technology; because the invention adopts N3520 type macroporous resin to dispose the distilled m-cresol hydrolysis liquid, the m-cresol is easily desorbed with a fast desorption rate and a short reaction cycle, thus being beneficial to the recycle of m-cresol. The preparation technology of m-cresol of the invention has a yield rate over 85 percent and purity over 99.5 percent.