53 results about "Glycol-chitosan" patented technology

The present invention relates to a glycol chitosane derivative, a preparation method thereof and a drug delivery system comprising the same. More specifically, the invention relates to a glycol chitosan derivative, which can form nano-sized self-assembled structures and has both temperature sensitivity and biodegradability so as to be suitable for use as a drug delivery system, as well as a preparation method thereof and a drug delivery system comprising the same.

The invention relates to the field of sewage treatment, and discloses a preparation method of a magnetic sewage treatment agent. The preparation method comprises the steps of weighing ferroferric oxide nano magnetic powder, adding pure water for ultrasonic dispersion, and obtaining a dispersion solution; weighing a dispersing agent, dissolving the dispersing agent into anhydrous ethanol, adding the dispersion solution, and conducting ultrasonic treatment to obtain a stable dispersion solution; under ultrasonic conditions, adding an aqueous solution of polyethylene glycol chitosan grafted materials into the stable dispersion solution, and obtaining coated magnetic nanoparticles; adding the coated magnetic nanoparticles into a bismuth nitrate solution, then adding a molybdate solution, and obtaining a solvothermal reaction system; making the system subjected to a solvothermal reaction to obtain a reaction product; obtaining the magnetic sewage treatment agent after the reaction product is washed, centrifuged, dried and calcined at high temperature. The preparation method has the advantages that the process is simple, the cost is low, catalyst load is firm, the thickness of a coatinglayer on the surface of each magnetic nanoparticle is small, the magnetic properties of the particles cannot be influenced, and the preparation method of the magnetic sewage treatment agent is suitable for industrial production.

The invention relates to a compound microsphere for orderly releasing growth factors and antibiotics and its preparation method and application. The PLGA microspheres co-loaded with growth factors and antibiotics are modified by ethylene glycol chitosan, wherein the antibiotics are encapsulated in ethylene glycol. The chitosan shell contains growth factors in the PLGA core; the composite microspheres have an orderly release function, and the antibiotics in the shell are released quickly to achieve rapid anti-inflammatory effects, while the growth factors in the core are slowly released to induce tissue regeneration. The composite microsphere prepared by the invention has high drug encapsulation rate, simple preparation process and easy industrialization; it can be applied to the preparation of carrier materials for repairing diseased and defective periodontal tissue, bone or cartilage tissue.