Polyethylene glycol/chitosan microsphere composite biological medical dressing

Abstract

The invention relates to a polyethylene glycol / chitosan microsphere composite biological medical dressing and belongs to the field of medical dressings. The method includes the steps that firstly, chitosan powder and an acetic acid solution are selected, mixed and stirred to be in an emulsion state; the mixture in the emulsion state has a cross-linking reaction with ethylene glycol and a NaOH solution, reactants are washed to be neutral with deionized water, and blank chitosan microsphere carriers are obtained after suction filtration, suction extraction and drying; polyethylene glycol is dissolved in boiled water and stirred, dibenzyl isopropyl phenyl phenol emulgators and the like are added after the temperature is lowered, chitosan microspheres are added after the dibenzyl isopropyl phenyl phenol emulgators are evenly mixed and dissolved; then hydrochloric acid is added, and after being completely foamed, a mixed solution is injected into a polyethylene mold; an obtained product is taken out and repeatedly washed with distilled water, and the polyethylene glycol / chitosan microsphere composite biological medical dressing can be obtained through drying. The polyethylene glycol / chitosan microsphere composite biological medical dressing has the advantages that the healing time of a wound is short, the dressing does not adhere to the wound, and the pain of a patient is relieved; the dressing is easy to operate and low in needed cost.

Description

technical field [0001] The invention relates to a polyethylene glycol / chitosan microsphere composite biomedical dressing, which belongs to the field of medical dressings. Background technique [0002] There are a large number of patients with skin defects in our country and the whole country every year, mainly due to safety accidents, burn patients and patients with large-scale skin ulcers caused by diseases, the development of chemical industry and current industry, modern weapons and frequent wars, the number of burn patients is increasing every year. With the rapid increase of the aging population and the deterioration of the environment, the number of people with large areas of skin ulcers caused by diseases such as diabetes has increased. Therefore, the demand for biological dressings is increasing day by day. [0003] At present, traditional methods rely on chemical drugs or antibiotics to achieve antibacterial and bactericidal purposes, so it is difficult to avoid ad...

AI Technical Summary

Problems solved by technology

[0003] At present, traditional methods rely on chemical drugs or antibiotics to achieve antibacterial and bactericidal purposes, so it is difficult to avoid adverse irritation and drug-resistant strains to human skin. At the same time, the most commonly used clinical dressing is gauze. This inert dressing , although it has the advantages of good absorption, wound protection, simple production, and cheap price, but because it cannot keep the wound moist, it is easy to adhere to the wound, and cannot prevent bacterial invasion, etc., it is powerless to infection and suppuration of the wound, and has no effect on wound healing. Obvious promotion effect, causing re-injury to the new tissue when changing the dressing, increasing the pain of the patient