The invention discloses formula components, a preparation process and other contents of a polytetrafluoroethylene modified vinyl floor coating, which is called FVC floor coating for short, the coating comprises three components of A, B and C, wherein the A component is prepared by 9 substances of vinyl resin, polytetrafluoroethylene resin, polyvinyl chloride resin, anionic carboxylic polymer dispersant and the like, the B component is methyl ethyl ketone peroxide, and the C component is cobalt naphthenate. When in use, the A component, the B component and the C component are mixed for preparing the polytetrafluoroethylene modified vinyl floor coating according to the weight ratio of 100: 1.5-4: 1.5-4. The invention simultaneously discloses a formula and the preparation process of producing an anti-corrosion floor by using the polytetrafluoroethylene modified vinyl floor coating, and the polytetrafluoroethylene modified vinyl floor coating is characterized by excellent chemical medium corrosion resistance, weather resistance, oil resistance, water resistance, good mechanical properties, construction performance and the like, as well as long service life, and good anti-cracking performance, and can be used in chemical industry, petroleum, foods, pharmaceutical industry and the like as protective materials of surface layers of basal bodies, such as concrete floors, wall surfaces and other building structures, members and the like.