The present invention discloses honeysuckle compound drink and a preparation method thereof. The honeysuckle compound drink comprises the following raw materials in mass ratios: 60-80% of distilled honeysuckle liquid, 5-15% of polysaccharide and flavone extractum, 0.5-2% of volatile oil (containing linalool, honeysuckle ethanol and geraniol), 0.5-2% of chlorogenic acids, 1-5% of bifidus factors, 5-10% of a sweetness adjusting agent, and 0.02-0.05% of vitamin C. The preparation method consists of the following steps: material selecting, distilled honeysuckle liquid preparing, blending, filtering and filling, sterilizing, detecting and packaging, and storing. The heat clearing and toxin removing honeysuckle compound drink is designed for children, and the bifidus factors, vitamin C and other materials beneficial to children's physical and mental health are added, so that the drink is good in taste and nutrient-rich, can regulate the beneficial flora in intestines, supplement energy, improve absorption, and enhance immunity, is simple in production processes and low in costs, does not need to consume a large amount of water and electricity, and is green, environmentally protective, energy-saving, and suitable for industrial production.