The invention provides a traditional Chinese medicine for treating infectious serositis of duck. The raw material medicines of the traditional Chinese medicine comprise jasmine, radix scrophulariae, root of common peony, Coptis chinensis, cassia twig, Rhizoma Osmundae, solanum lyratum, asiatic toddalia root, tabasheer, Philippine flemingia root, hedyotis hedyotidea, Rhizoma Atractylodis Macrocephalae, Angelica sinensis, honeysuckle, seed of feather cockscomb, acanthopanax, abrus cantoniensis hance, Polygonum cuspidatum, sargentgloryvine stem, groundsel, glossy privet fruit, verbena, Brucea javanica, Chinese Tamarisk Twig, moutan bark, madder, pericarpium citri reticulatae, sealwort and sealwort. The traditional Chinese medicine has the advantages of no toxicity, no harmful residue, environmental friendliness and no tolerance, and has remarkable effect for treating infectious serositis of duck.