Oleum fructus bruceae soft capsule and preparation method thereof
A technology of bruce japonica oil and soft capsule, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as greasy feeling, nausea, etc., achieve accurate content, avoid exudation, and save absorption. Effect
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Embodiment 1
[0025] Weigh 4000g of Brucea javanica oil, 2500g of gelatin, 875g of glycerin, 10g of antioxidant, and 0.7g of preservative, put gelatin, glycerin, and water in a plastic bucket at a ratio of 1:0.35:0.90, heat to dissolve at 90°C, and add preservative , while stirring for 2 hours, after vacuum degassing, keep warm at 70°C for later use.
[0026] Mix the antioxidant into javanica javanica oil, stir and mix well, let it stand to dissolve, and degas it by ultrasonic for later use.
[0027] Adjust the temperature of the plastic box of the SCM-100 soft capsule machine to 50°C, the temperature of the spray body to 41-43°C, and the thickness of the rubber to 0.7-0.8mm. Pour the medicinal liquid into the medicinal liquid hopper, and press the soft capsule with a mold.
Embodiment 2
[0029] Weigh 2000g of Brucea javanica oil, 400g of gelatin, 140g of glycerin, 5g of antioxidant, and 0.4g of preservative, put gelatin, glycerin, and water in a plastic bucket at a ratio of 1:0.35:0.90, heat and dissolve in a water bath at 95°C, and add antiseptic agent, stirred for 2 hours at the same time, after vacuum degassing, keep warm at 80°C for later use.
[0030] Mix the antioxidant into javanica javanica oil, stir and mix well, let it stand to dissolve, and degas it by ultrasonic for later use.
[0031] Adjust the temperature of the plastic box of the SCM-100 soft capsule machine to 50°C, the temperature of the spray body to 41-43°C, and the thickness of the rubber to 0.7-0.8mm. Pour the medicinal liquid into the medicinal liquid hopper, and press the soft capsule with a mold.
Embodiment 3
[0033] Weigh 3000g of Brucea javanica oil, 1500g of gelatin, 525g of glycerin, 8g of antioxidant, and 0.5g of preservative, put gelatin, glycerin, and water in a plastic bucket at a ratio of 1:0.35:0.90, heat and dissolve in a water bath at 80°C, and add antiseptic agent, stirred for 2 hours at the same time, after vacuuming and degassing, keep warm at 55°C for later use.
[0034] Mix the antioxidant into javanica javanica oil, stir and mix well, let it stand overnight to dissolve it, and degas it by ultrasonic for later use.
[0035] Adjust the temperature of the plastic box of the SCM-100 soft capsule machine to 50°C, the temperature of the spray body to 41-43°C, and the thickness of the rubber to 0.7-0.8mm. Pour the medicinal liquid into the medicinal liquid hopper, and press the soft capsule with a mold.
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