43results about How to "High value of industrial production" patented technology

The invention relates to a method for preparing 7-dehydrocholesterol, which comprises the following steps: 1) protecting hydroxyl on the 3-site of cholesterol; 2) oxidizing carbon on the 7-site of the product obtained in step 1) into carbonyl; 3) carrying out a hydrazone reaction on the product obtained in step 2) and a hydrazine derivative; 4) reacting the product obtained in step 3) with a strongly alkaline reagent; and 5) reacting the product obtained in step 4) with water or an acid. The method has the advantages of simple operation process, less secondary reaction, high yield and less corrosion to equipment, thereby having high industrial production values.

The invention discloses a mutant of β-galactosidase and its preparation method and application, belonging to the fields of genetic engineering and enzyme engineering. By mutating the amino acid at a specific site in β-galactosidase, transferring it into the recombinant bacteria, and performing enzyme transformation under optimized conditions, the yield of galactooligosaccharides produced by the mutant reached 59.8%, which was higher than that of the wild The enzyme is increased by about 70%, and the yield of galactooligosaccharides is increased, which has extremely high industrial application.

The invention provides a novel preparation method for Mitiglinide calcium hydrate. The method comprises the following steps: adopting cis-hexahydroisoindole as a raw material, conducting acylation reaction, hydrocarbonylation reaction, hydrolysis reaction, and salt forming reaction on the raw material, and obtaining the Mitiglinide calcium hydrate; a one-port process method is adopted for conducting the hydrocarbonylation reaction and the hydrolysis reaction, and the product purity can reach over 99.8%, and the yield can reach over 36%. The preparation method for Mitiglinide calcium hydrate has the advantages of the easy-to-get raw material, mild reaction condition, simple and practicable operation, and relatively high yield, therefore, the method has relatively higher industrial production value, and industrialization has been realized at present.

The invention discloses a comprehensive water-saving process for producing stevioside. Down-column water generated in a resin adsorption step is subjected to purification treatment and a waste acid, a waste alkali and waste water, which are generated in an adsorption resin and desalting and decolorizing resin regeneration step are subjected to treatment, in the production procedure of the stevioside. According to the comprehensive water-saving process, a water extracting solution of a stevia leaf is subjected to resin adsorption; down-column waste water is subjected to rough filtration, primary filtration, ceramic film filtration, resin adsorption treatment, ozone treatment, adsorption filtration and reverse osmosis treatment in sequence to obtain purifier water which is directly used for the water extraction of the stevia leaf; abundant waste acid, waste alkali and waste water, which are produced in a resin regeneration procedure, are recycled; a water consumption is decreased by 70 percent or above; an acid consumption and an alkali consumption are decreased by 60 percent or above; meanwhile, by-products flavone and chlorogenic acid are obtained. According to the comprehensive water-saving process, a new pollutant does not be generated; no new chemical reagents are put; the quality of treated water is high; part of indexes are superior to those of underground water and municipal water; the ash content of a stevioside product can be decreased; the improvement of the purity and the yield of the product is facilitated; the industrial production value of the stevioside is improved.

The invention discloses a synthesis method of N-methyl-2-hydroxyethyl hydroxyethyl, which comprises the following steps of: (1) adding dimethyl sulfate and N-methyl pyrrolidone into a reaction kettle for reaction; (2) cooling and dropwise adding an ethanol solution of sodium ethylate, continuously dropwise adding ethyl cyanoacetate, reacting and filtering to obtain an intermediate (I); (3) addingthe intermediate (I) and a catalyst as well as a high-boiling point organic solvent to the reaction kettle, heating, fractionating, reacting, filtering, recovering propylene glycol, and carrying vacuum rectification to obtain a intermediate (II); and (4) adding the intermediate (II) and the catalyst as well as a solvent into the reaction kettle, replacing by using nitrogen and hydrogen sequentially, introducing hydrogen, reacting, cooling, evacuating, filtering, evaporating out moisture content, and carrying out vacuum rectification to obtain the N-methyl-2-hydroxyethyl hydroxyethyl. The synthesis method has the advantages of cheap and easily obtained raw materials, short synthesis route, mild reaction conditions, relatively low production cost and higher overall yield.

The invention belongs to the technical field of 3D printing, and in particular relates to an automatic leveling system and a leveling method for a forming platform of laser selective melting forming equipment. It adopts the concept of fully automated control modular design, rebuilds the leveling system of the manufacturing equipment platform, realizes the convenience of 3D printing substrate leveling preparation, removes manual, automation, improves production efficiency, and ensures product quality. It is suitable for the leveling of industrial-grade 3D printing platforms, especially in the area of ​​metal selective melting and forming technology. It is oriented to the future automatic production line mode, and the automatic leveling system and method have extremely high industrial production value in the field of future equipment manufacturing.

The invention discloses a near-infrared second-region fluorescent compound capable of targeting mitochondria as well as a preparation method and application thereof. According to the compound, the emission wavelength ranges from 600 nm to 1200 nm and can reach the near-infrared second-region (900-1200 nm) after the compound is modified by different functional groups. The compound can be used for the biological fields of mitochondrion imaging, photo-thermal therapy and osteosarcoma and whole-body bone imaging; and added modified sites can be used for connecting different bioactive groups, so that the water solubility, the biocompatibility and the targeting property are improved, and the compound can also be used for in-vitro detection of various disease markers and in-vivo early diagnosis of breast cancer, brain glioma, colon cancer, liver cancer and the like. The fluorescent compound has the advantages of being novel in structure, simple in synthesis steps, resistant to photobleaching,non-toxic, good in biocompatibility and excellent in industrial production value and biomedical application prospect.

The invention discloses an energy-saving and environment-friendly type flue gas filtering system. The energy-saving and environment-friendly type flue gas filtering system comprises a dust filter, a gas absorption tank, an adsorption pot and an exhausting pipe; dust solid particles in flue gas are removed through the dust filter; the gas absorption tank is used for absorbing and removing acidic gas including carbon dioxide, sulfur dioxide and the like in the flue gas; an adsorbent in the adsorption pot is used for adsorbing and removing carbon monoxide in the flue gas; preparation of the adsorbent in the adsorption pot comprises the following steps: firstly, enabling ruthenium trichloride and sodium periodate to react in an acidic environment, and oxidizing ruthenium trichloride into a high-valence ruthenium compound; then loading the high-valence ruthenium compound into modified chlorite and sufficiently dispersing the high-valence ruthenium compound in the surface and pore channels of the modified chlorite, wherein high-valence ruthenium can be complexed with 4 carbon monoxide at the same time, and the adsorption amount of the chlorite adsorbent on carbon monoxide is 130ml / g or above and is much higher than the loading amount of an existing transition metal loaded adsorbent on the carbon monoxide, so that the adsorbent has relatively high industrial production value.

The invention belongs to the field of chemical synthesis, and discloses an asymmetric synthesis method of D-halopheniramine, which comprises: under the condition of the presence of alkali, 3-(2-pyridyl) ethyl acrylate acts on a chiral rhodium catalyst The asymmetric addition product can be obtained by reacting with 4-chlorophenylboronic acid or 4-bromophenylboronic acid, and the single-step yield can reach up to 96%, and the ee value can reach 96%; the asymmetric addition product can be hydrolyzed to obtain the corresponding acid, acid Condensation with dimethylamine hydrochloride gives the corresponding amide; reduction of the amide gives the desired final product. The raw material of this route is cheap and easy to obtain, the route is short, the enantioselectivity of the product is high, the total yield is about 75%, and it has high industrial production value.

The invention belongs to the field of 3D printing equipment, and in particular relates to a modular forming system suitable for automatic production line 3D printing equipment and a use method thereof. It includes working cabin frame, forming cylinder module, material supply cylinder module, collection cylinder module and lower base module. The internal structure of the collecting cylinder includes the worktable base plate, lifting motor, parallel guide rod, power connector and other components; the lower base mainly includes the base plate, lifting motor, horizontal push-out motor, power connector and other components, and the base plate can carry the above forming cylinder, material supply Cylinder, collection cylinder module, when lifting the motor, the cylinder module is raised, the motor is pushed out horizontally to take out the cylinder module, the lower base is lowered, and then the cylinder module is pushed out, so that functions such as replacement can be realized. The invention realizes the modularization of 3D printing preparation work, printing process, and cleaning after completion, realizes streamlining of operations, combination of functions, and convenience, and realizes production line mode manufacturing.

The invention belongs to the technical field of chemical synthesis and discloses a dithiocarbamate synthesis method. The dithiocarbamate synthesis method comprises that in an organic solvent, Ar-B(OH)2, NHR1R2 and carbon disulfide as raw materials and a copper salt and alkali as promoters undergo a reaction at a temperature of 60-120 DEG C for 10-24h with stirring, after the reaction, the reaction product is cooled to a room temperature, then is filtered and then is subjected to reduced pressure distillation for solvent removal so that a crude product is obtained, and the crude product is purified by column chromatography so that dithiocarbamate is obtained. The dithiocarbamate synthesis method realizes dithiocarbamate synthesis by one step, has simple and easy processes and a high product yield, utilizes cheap and easily available raw materials, has a low synthesis cost and has great industrial production values.