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306 results about "Suppository drug" patented technology

The medication used in suppositories, bisacodyl and glycerin, are considered stimulant laxatives. When the suppository is inserted about an inch inside the rectum it begins to melt releasing the medication.

Anti-infection compound preparation and its preparation method

The anti-infective medicine, including powder, mixture, aerosol, capsule, injection, suppository, ointment and microcapsule, is characterized by that on the theroretical basis of combining traditional Chinese medicine and modern immunology the immunoglobulin, effective components of Chinese medicinal materials which are extracted according to the compound prescription and auxiliary preparation are combined together organically, and undergone the fine preparation process to obtain a high-efficiency, safe, stable, environment-protecting type anti-infection medicine having no toxic side effect and having no drug resistance.
Owner:张勇飞 +2

Low frequency vibration assisted blood perfusion emergency system

InactiveUS20050054958A1Improve localized drug effectivenessImprove vibrationElectrotherapySurgeryVascular obstructionFourth intercostal space
An emergency system for treatment of a patient (20) experiencing an acute vascular obstruction, employing a non-invasive vibrator (10), optimally in conjunction with drugs, for disrupting and lysing thromboses, relieving spasm (if associated), and thereby restoring blood perfusion. Vibrator (10) is operable in the sonic to infrasonic range, with a source output of up to 15 mm. For acute myocardial infarction cases, a pair of contacts (12), are advantageously placed to bridge the sternum at the fourth intercostal space. Vibration is initiated at 50 Hz (or any frequency, preferably within the 20-120 Hz range), and is ideally adjusted to a maximal amplitude (or force) deemed tolerable and safe to the patient (20), preferably with the administration of thrombolytic agents or other form of drug therapy. A synergistic effect is achieved between vibration and drugs to facilitate the disruption of thromboses, relieve spasm, and restore blood perfusion. In a variation, ultrasonic imaging may be used to direct vibration therapy.
Owner:PARALLEL BIOTECH LLP +1

Medical device with therapeutic agents

A medical device is adapted for at least partial implantation into a body and includes first and second sections along the length of the device. A first therapeutic agent is associated with the first section and a second therapeutic agent is associated with the second section. The first therapeutic agent can be one or more antiproliferative, such as paclitaxel, a paclitaxel derivative, or a paclitaxel pro-drug, anti-coagulant, antithrombotic, thrombolytic, fibrinolytic, or combination thereof. The second therapeutic agent can be one or more antimicrobials, such as one or more antibiotics. Each of the first and second therapeutic agents can either be posited on one or more surfaces of the respective section, or impregnated within the section. The device can include a separator to space the first and second sections. A method of making a medical device and a method of establishing access to a vessel within a body are also provided.
Owner:COOK MEDICAL TECH LLC

Therapy for enteric infections

ActiveUS8772242B2Antibacterial agentsBiocideNervous systemDiverticulitis
There is disclosed herein a composition for treating gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhea, chronic idiopathic nausea, IBD-associated constipation and diarrhea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the composition comprising: (i) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (ii) at least one anti-clostridial agent selected from the above combined with an opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhea, chronic idiopathic nausea, IBD-associated constipation and diarrhea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the method comprising administering orally, via enema or by suppository: (i) a composition of the invention; (ii) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (iii) at least one anti-clostridial agent selected from the above and an opioid blocking agent to a patient in need of such treatment.
Owner:BORODY THOMAS JULIUS

Toad peptide antibiotics separated from toad maggots and preparation method of antibacterial drugs thereof

The invention provides toad peptide antibiotics separated from toad maggots and a preparation method of antibacterial drugs thereof. The preparation method comprises the following steps: taking toad maggots as raw materials; carrying out ultrafiltration and microfiltration, gel chromatography separation, ultrasonic standing wave liquid preparation chromatography and the like by adopting a solvent extraction method and an ion-exchange resin adsorption method; freeze-drying to prepare the toad peptide antibiotics; and combining the active components with appropriate excipients to prepare tablets, capsules, suppositories, ointments, enteric tablets and the like to be used for treating various diseases. The drugs prepared by the invention have the advantages of wide antibacterial range, specific drug components, controllable quality and stable performance and have industrial production values.
Owner:HARBIN INST OF TECH

Low molecular weight carboxyl-reduced derivatives of fucosylated glycosaminoglycans and preparation method and applications of low molecular weight carboxyl-reduced derivatives

The invention discloses low molecular weight carboxyl-reduced derivatives of fucosylated glycosaminoglycans (LCRG). The extent of carboxyl reduction is not less than 20%. Weight-average molecular weight of the LCRG is about 3000-20000Da, and monosaccharides comprise acetyl galactosamine (GalNAc), glucose (Glc) or glucuronic acid (GlcUA) and fucose (Fuc) or sulfates of fucose (shown as -OSO3-). The mole ratio of GalNAc, Glc (containing GlcUA), Fuc and -OSO3- is about 1: (1+-0.3): (1+-0.3): (3.0+-1.0). The LCRG is a potent human immunodeficiency virus (HIV) Type 1 entry inhibitor which acts on conserved regions and has the advantages of high activity against HIV Type 1, high therapeutic index and no-drug-resistance, and the LCRG can be used for preventing or curing HIV. The invention further provides a preparation method of the LCRG. The carboxyl-reduced derivatives of fucosylated glycosaminoglycans and medicinal compositions of the carboxyl-reduced derivatives can be prepared into injection agents, lyophilized powder or suppository and the like.
Owner:KUNMING INST OF BOTANY - CHINESE ACAD OF SCI +1

Low molecular weight glycosylated chondroitin sulfate and its purpose in preparation of anti-HIV-1 medicament

The invention discloses a low molecular weight glycosylated chondroitin sulfate, whose weight average molecular weight is 3000-15000Da. The monosaccharide composition comprises acetyl galactosamine (D-GalNAc), glucuronic acid (D-GlcUA), fucose (L-Fuc), or its sulfuric ester (expressed in -OS03<->), wherein the mole ratio of D-GalNAc to D-GlcUA to L-Fuc to -OS03<-> is 1: (1+ / -0.3): (1+ / -0.3): (3.5+ / -0.5). The low molecular weight glycosylated chondroitin sulfate has a strong anti-HIV-1 virus activity, is a gp120 entry inhibitor, and can be used for preventing and / or treating AIDS. The invention also provides a method for preparing the low molecular weight glycosylated chondroitin sulfate and its composition preparation. Glycosylated chondroitin sulfate is depolymerized by the peroxide method to obtain a low molecular weight product, and then low molecular and / or high-molecular impurities of the product are removed by gel separation or ultrafiltration method. The low molecular weight glycosylated chondroitin sulfate and its medicinal composition can be prepared in the form of an injection, a lyophilized powder or a suppository.
Owner:KUNMING INST OF BOTANY - CHINESE ACAD OF SCI +1

Medicine composition, preparing method and use for preparing gynacecopathia medicine

A Chinese medicine in the form of tablet, capsule, powder, particles, oral liquid, or injection for treating gynopathy is prepared from 10 Chinese-medicinal materials including ginseng, cnidium fruit, astragalus root, mother wort, etc through unique process. Its advantages are quickly taking its effect, high cure rate and short course of treatment.
Owner:HARBIN OT PHARMA

Composition and method for enhancing fibrinolysis

The present invention relates to a novel alpha-2-antiplasmin-binding molecules and treatment for pulmonary embolism, myocardial infarction, thrombosis or stroke in a patient which comprises administering an alpha-2-antiplasmin-binding molecule capable of preventing inhibition of plasmin by endogenous alpha-2-antiplasmin. The invention also relates to a treatment for pulmonary embolism, myocardial infarction, thrombosis or stroke in a patient comprising coadministrating an alpha-2-antiplasmin-binding molecule of the invention together with a thrombolytic agent.
Owner:PRESIDENT & FELLOWS OF HARVARD COLLEGE +2

Application of effective part of cockroach extract in preparing drug for inhibiting fungus growth

The invention relates to application of an effective part of a cockroach extract in preparing a drug for inhibiting fungus growth, and particularly relates to application of an effective part obtained by refining a crude cockroach extract through macroporous adsorption resin in the aspect of preparing a drug capable of resisting fungal infection. The effective part is refined from a fresh or dried Periplaneta americana L. polypide product through alcohol and water extraction, macroporous adsorption resin column chromatography and alcohol solvent elution, and has an obvious inhibition effect on the growth activity of candida albicans and a fungus growth inhibition capacity 80 times higher than that of fluconazole and 5-fluorocytosine and 800 times higher than that of amphotericin. The effective part of the cockroach extract can be prepared into forms, such as a hydrogel, a frothy gel, a cataplasm, freeze-dried powder, a water aqua, an aerosol, a suppository, a film, an external liniment, an ointment and the like, and is used for preparing pharmaceutical preparations for preventing and curing fungal infection, medical appliances and daily-use chemical products.
Owner:DALI UNIV

Chinese medicinal composition for treating gynaecologic inflammation and preparation thereof

The invention discloses a herbal composite and a preparation thereof for treating gynecological inflammation. The herbal composite is prepared of cotyledon, selinum, sophora, phellodendron, radix Stemonae, agrimonia, sanqi, borax, borneol; the weight ratios are that 3-15 portions of cotyledon, 3-15 portions of selinum, 3-15 portions of sophora, 2-10 portions of phellodendron, 2-10 portions of radix Stemonae, 2-10 portions of agrimonia, 0.2-2 portions of sanqi, 3.03-0.3 portion of borax, and 0.06-0.6 portion of borneol. The preparation can be suppository, gel, cream, solution agent, film, spray, effervescent tablets agent, and other externally used preparations. The invention adopts common herbal medicines as materials, the usage cost of a sufferer is lower, the content of the effective components are high, the stability is high, and the curative effect is notable. The herbal composite and the preparation of the invention can reduce fever, destroy the toxic properties, dry dampness, kill insect, remove rot, and produce fresh, can inhibit and kill pathogenic micro-organisms and infusorium, can improve the immunity of organism, can cure tickle and relieve pain, can accelerate metabolism, can promote the tissue to rebirth. The prescription is applicable for the sufferers with leukorrhea with reddish discharge, pruritus vulvae, cervical erosion, infusorium vaginitis, mucedine vaginitis, nonspecific vaginitis, etc.
Owner:谢晓涛 +1

Allicin cyclodextrin clathrate compound, formulation and its preparation method

The invention discloses a garlicin cyclodextrin clathrate compound, preparation and the process for preparing same, wherein the allicin, cyclodextrin or their derivatives (such as beta-cyclodextrin, hydroxypropyl-beta-cyclodextrin) can be used for preparing garlicin cyclodextrin clathrate compound, which can be used for preparing various preparations of different oral preparation, suppositorium, spray, and injection.
Owner:毛友昌

Cyclosporin A dispersion solid and its preparation method

A dispersing solid (capsule, tablet, particle, suppository and dripping pill) of cyclosporin A is prepared from cyclosporin A and carrier by solvent method, solvent fusion method, etc. It has high solubility of easy absorption.
Owner:FUDAN UNIV +1

Buyang huanwu gantong medicine for preventing and curing cardiovascular or cerebrovascular disease and the agent and the method for preparing the same

InactiveCN101036705AEffective ingredients are clear and controllableQuick effectPowder deliveryAnthropod material medical ingredientsDiseaseBuyang huanwu
The invention discloses a yang supplementing five returning ketoside drug for preventing and treating cardio-cerebrovascular diseases, which is prepared by extracting active ingredient from raw materials of hoantchy root, angelica, red paeonia, hemlock parsley, earthworm and peach kernel. The obtained drug has total glucosides of the hoantchy root as 30-60%, total glucosides oftotal glucosides of the red paeonia as 5-20%, content of safflower flavone as 5-10%, and the remains as the other ingredients extracted from the traditional Chinese medicine materials. The yang supplementing five returning ketoside drug provided by the invention can be added with accessories or auxiliary components acceptable in pharmacy to form various preparations required by clinic. The preparations are: small injection solution, transfusion, freeze-dried powder, tablet, capsule, oral solution, buccal tablet, granule, medicinal granules, pill, powder, suspension, suppository, drop, dropping pill, sustained release preparation, release controlling agent and targeting preparation. The drug of the invention has clearly controllable efficacious components, fast absorption, definitive curative effect, convenience for taking and is effective for preventing and treating cardio-cerebral ischemia diseases.
Owner:合肥七星医药科技有限公司

Cancer treating

The invention provides a medicinal composition of Cinobufacini, which is prepared into the forms of drop pill, or dispersible tablet, or soft capsule, or effervescent tablet, or orally disintegrating tablet, or mini-pill, or suppository. The invention also discloses their preparing process. The composition comprises dried toad skin extract and Job's-tears seed oily extract by the weight ratio of 1:0.05-30.
Owner:叶耀良

Chinese medicine preparation for treating chronic prostatitis and preparation method thereof

The invention relates to a Chinese medicine preparation for treating chronic prostatitis, which is characterized by comprising the following raw medicines: radix rehmanniae preparata, cynomorium songaricum rupr, radix astragali, rhizoma corydalis, herba epimedii, dodder, herba ecliptae, schisandra chinensis, hedyotis diffusa, safflower, radix polygoni multiflori preparata, fructus ligustri lucidi, salvia miltiorrhiza, radix paeoniae alba, myrrh, prunella vulgaris, fructus cnidii, herba patriniae, scutellaria baicalensis georgi, angelica and cortex moutan. In the invention, Chinese herbal medicines for promoting blood circulation and removing blood stasis are adopted, the permeability of capillaries can be improved, inflammation reaction can be alleviated, the extinction and the absorption of inflammation focus can be promoted, the metabolism of connective tissues can be improved, the transformation and the absorption of hyperplastic lesions can be promoted, and atrophic connective tissues can recover. When the Chinese medicine preparation for treating chronic prostatitis is applied through rectums, the medicines can be absorbed in the rectums, enema or suppository enables the medicines to be absorbed through rectum mucosa to directly reach affected parts; and the Chinese medicine preparation can reach higher consistency in diseased prostate and has the advantages of ideal treating effect, low price and simple, convenient and practical preparation method.
Owner:郭瑶

Methods of treatment using topical copper ion formulations

Provided herein are topical formulations containing copper ions and methods of treating radiation dermatitis, damage caused by radiation therapy, or other radiation-induced damage conditions in various areas of the body using such formulations. Methods of treating radiation dermatitis using topical copper ion treatments are provided. A topical treatment in its basic form comprises a biocompatible copper ion solution or suspension obtained by leaching of the copper ions from copper metal. The copper ion solution or suspension is combined with various carriers to form the copper ion treatment including creams, gels, lotions, foams, pastes, tampons, solutions, suppositories, body wipes, wound dressings, skin patches, and suture material. Methods of making the copper ion solution or suspension from solid copper metal in a biocompatible solution are also provided.
Owner:CDA RES GROUP

Diffusion enhancing compounds and their use alone or with thrombolytics

The subject invention relates to diffusion enhancing compounds and their use alone or with thrombolytic agents for the treatment of disorders resulting from the formation of a thrombus such as a myocardial infarction or stroke.
Owner:DIFFUSION PHARMA LLC

Use of clostridium butyricum in preparing medicine composition for preventing and curing intestinal cancer

The invention discloses the novel application of clostridium butyricum to drugs, in particular to the application of the clostridium butyricum to the preparation of a drug combination used for preventing and treating intestinal cancer. The novel application comprises the prevention of chronic intestinal disease canceration such as intestinal polyp, Crohn disease, ulcerative colitis, etc., the adjuvant therapy on advanced inoperable intestinal cancer, the adjuvant therapy after the intestinal cancer operation, etc.; the clostridium butyricum is selected from (but is not limited to) clostridium butyricum, CGMCC, and storage serial number 0313.1. In the forms of live bacteria and pharmic receivable different carriers, the clostridium butyricum is made into tablets, capsules, powders, liquid preparations, suppositories, and enemas; the clostridium butyricum can be used for preventing and treating the intestinal cancer for a long time through the methods of oral administration, clysis, injection in the tumor tissue; therefore, the life of a patient suffering from the intestinal cancer is prolonged, and the life quality of the patient suffering from the intestinal cancer is increased.
Owner:QINGDAO EASTSEA PHARMA +1

Ciclopirox olamine pessary and preparation method thereof

The invention relates to a ciclopirox olamine pessary capable of reducing toxic and side effects of a medicament caused by systemic delivery, increasing local concentration of the medicament, fully playing the therapeutic effectiveness of the medicament and improving the adaptability of patients. The pessary can realize zero order release and is prepared by the following materials by weight portion: 1 portion of ciclopirox olamine, 65 to 90 portions of substrate, 0.2 to 3 portions of stearic acid, 0.1 to 5 portions of hydrogenated castor oil and 0.05 to 2 portions of sodium benzoate.
Owner:HAINAN YONGTIAN PHARMA INST

Anti-cervical erosion suppository and preparation method thereof

The invention relates to the field of traditional Chinese medicines and provides an anti-cervical erosion suppository and a preparation method thereof. The anti-cervical erosion suppository is prepared from ginsenoside, lithospermum, golden cypress, sophora flavescens, dried alums and acacia catechu. The preparation method comprises the following steps: grinding the acacia catech and the dried alums into fine powder; grinding borneol; adding water into the golden cypress, the sophora flavescens and the lithospermum and decocting for three times; mixing decoction solutions and filtering; adding ethanol and standing for 24 hours; recycling the ethanol and concentrating into thick paste; drying and crushing into fine powder; uniformly mixing with the fine powder; additionally adding base materials including polyoxyl stearate and polyethylene glycol 1500; mixing, heating and smelting; and adding the fine powder and uniformly agitating to prepare a suppository. The anti-cervical erosion suppository has good water solubility, no stimulation, no toxin, no anaphylaxis, and is stable in physicochemical property; the anti-cervical erosion suppository is not easily deformed due to moisture absorption and is not easy to mildew; at a room temperature, the anti-cervical erosion suppository has suitable rigidity and has no deformation and crushing in a packaging, transporting and storing process.
Owner:TONGHUA MAOXIANG PHARMA

Baicalin cyclodextrin clathrate compound, preparation and preparing method thereof

A scutelloside-cyclodextrin inclusion compound prepared from scutelloside and cyclodextrin or its derivative (beta-cyclodextrin or hydroxypropyl-beta-cyclodextrin), its various preparations including oral-applied ones, suppository, spray, injection, etc. and their preparing process are disclosed. Its advantages are high water solubility, stability and curative effect and low by-effect.
Owner:毛友昌

Medicine for preventing and treating senile dementia and its prepn and use

InactiveCN1931212AAvoid deficiencies of unclear active ingredientsImprove memory impairmentOrganic active ingredientsNervous disorderDiseaseEpimedium
The present invention is one kind of medicine for preventing and treating senile dementia and its preparation and use. The medicine has epimedium as the single ingredient, which is treated through solvent extraction, macroporous resin elution, drying and other technological steps to obtain epimedium total flavone used as the main component. The medicine is used in preventing and treating vascular dementia, Alzheimer disease and other senile dementia. It may be prepared into tablet, capsule, soft capsule, granule, dripping pill and other preparation forms.
Owner:南京宇道科技开发有限公司

Medicine composition of refreshing solid dispersion and its preparation and preparing process

The present invention relates to dispersed solid medicine composition, named as Xingnaojing, for treating infantile externally caused fever heat, infantile viral encephalitis fever heat, infantile supurative tonsillitis, senile cerebral vascular dementia and cerebral apoplexy in recovering stage. The solid medicine composition consists of musk, borneol, volatile curcuma root oil, total curcuma root curcumin and total cape jasmine glycoside, and is prepared into dripping pill, suppository, capsule, tablet, granule or other forms. The preparation process has separate extraction of the active components curcumin and total cape jasmine glycoside, high shearing technology and sealed circular apparatus for well maintenance of active components and quantitative indexes for the control of active components so as to ensure the stable quality and curative effect of the product.
Owner:托新权

Tranexamic acid external semisolid preparation and preparation method thereof

The invention belongs to the field of pharmaceutical preparations and particularly discloses a tranexamic acid external semisolid preparation and a preparation method thereof. The semisolid preparation is one of gels, suppositories and ointments prepared from tranexamic acid serving as an active ingredient and other pharmaceutically acceptable auxiliary materials. The tranexamic acid external semisolid preparation disclosed by the invention has high physiological skin compatibility, and the haemostatic effect of the tranexamic acid is effectively improved.
Owner:贵州健瑞安药业有限公司

Traditional Chinese medicine suppository and preparation method thereof

The invention is concerned with the Chinese traditional medicine suppository and the preparation method for treating and defending intestine paralysis, intestine conglutination and intestinal obstruction, composes of bark of official magnolia, rhubarb and fruit of immature citron that compounds with weight, which is by distill, filtration, concentration, dryness, crush to get dry cream powder, melts and mixes with the suppository base, irrigate module, cooling, gets the suppository. The invention is fast effect and dramatic curative effect.
Owner:JINAN KANGZHONG PHARMA TECH DEV

Medicinal preparation of general alkaloid of bocconia cordata and producing method

An externally-applied medicine in the form of effervescent tablet, capsule, or suppository for treating gynopathy is prepared from pink plumepoppy herb's alkaloid and medicinal auxiliary. Its advantage is high curative effect. Its preparing process is also disclosed.
Owner:张晴龙

External-use sertaconazole nitrate suppositorium

The invention provides an external nitric acid Sertaconazole suppository, which is a suppository of different specifications made by mixing the powder of ground nitric acid Sertaconazole and melt suppository base, glycerol and Polysorbate 80. The suppository has the beneficial effects that the preparation process of the suppository is simple, the eutherapeutic and low-toxic nitric acid Sertaconazole are used as the main medicaments, a greater cure effect can be achieved by using a small amount of medicament for local application, mycotic infection is inhibited, the cure effect is good, the use is convenient, etc.
Owner:HAINAN HAISHEN TONGZHOU PHARM CO LTD

Traditional Chinese medicine extractive having bidirectional immunity adjustment effect and application

The invention discloses a paliurus ramosissimus extractive having the bidirectional immunity adjustment effect and application thereof as a medicine for treating immune function abnormalities. The traditional Chinese medicine extractive disclosed by the invention is a methanol, ethanol, ethyl acetate, petroleum ether or similar solvent extract of paliurus ramosissimus leaves, paliurus ramosissimus roots, paliurus ramosissimus stem leaves or paliurus ramosissimus whole plant and mainly contains terpenes, flavonoids, alkaloids, coumarins (including glycosides and monomers of the above substances), polysaccharides, cellulose and the like; the preparation of the traditional Chinese medicine extractive include tablets, capsules, emplastrums, granules, injections, suppositories, ointments, gels, plastics, linimentums, lotions and sprays. The paliurus ramosissimus extractive and the preparation thereof disclosed by the invention have the bidirectional immunity adjustment effect and can be applied to preparing the medicines for treating immunocompromise and autoimmune diseases.
Owner:四川梓橦宫药业股份有限公司
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