326results about How to "Reduce fatality rate" patented technology

The invention discloses an inpatient medical management quality assessment method which screens historical data and builds models, including authenticating and clearing data, DRG(Diagnosis Related Group)and model classifying, classification and collection of ICD complication and other variables during hospital admission, the statistic tests and screening of hospital admission and complication variables, the building of statistic models and quality assessment. The method also screens current data and calculates a predicated value, including predicated value of risk when a patient is sent in hospital, to realize risk predictions on the mortality rate of each patient, the days spent in hospital and the medical cost in hospital as well. According to the invention, the method effectively converts medical data to find solutions so as to achieve the values of data based on the analysis of big data, the mathematic statistical method and machine learning method. The method also makes medical data comparable. The method not only performs assessment to medical quality among diseases but also realizes proper assessment to managements of treatment in a hospital between doctors, between different departments and between different patients.

The invention of the invention discloses the use of imidazole alkaloids of a general formula (I) and pharmaceutically acceptable salts thereof in the preparation of anti-Infective medicament synergists and medicinal compositions containing the synergists.

The invention relates to a novel poultry micro-ecological preparation and a preparation method of the novel poultry micro-ecological preparation. The preparation comprises following components in part by weight: 0.8-3.5 parts of vitamin A, 0.2-0.8 part of vitamin D, 2-8 parts of vitamin E, 0.2-1.2 parts of vitamin K, 0.1-0.9 part of vitamin B1, 0.2-0.8 part of vitamin B2, 0.1-0.7 part of vitamin B6, 0.08-0.5 part of vitamin B12, 2-5 parts of nicotinamide, 0.8-3.5 parts of calcium pantothenate, 0.02-0.4 part of folic acid, 0.2-1.2 parts of biotin, 0.02-2 parts of vitamin C, 1.3-32 parts of enterococcus faecium, 27-155 parts of bacillus subtilis, 75-210 parts of oligosaccharide, 150-400 parts of pine needle meal and 400-600 parts of bentonite. The novel poultry micro-ecological preparation can improve daily gain, feed intake, feed conversation efficiency of young poultry, reduces death and culling rate of the young poultry, and improves reproductive performance of breeding poultry, laying rate, fertilization rate of hatching eggs, hatching rate, and healthy rate of the young poultry. According to the invention, as double-layer shallow coating is performed to enterococcus faecium, the stress resistance of enterococcus faecium is improved.

The invention discloses special feed for mandarin fish fries. The special feed comprises raw materials in parts by weight as follows: 20-80 parts of fish meal, 30-80 parts of prawn powder, 15-35 parts of blood worm powder, 2-8 parts of cod-liver oil, 1-3 parts of palm oil, 1-4 parts of citrus oil, 10-30 parts of bone meal, 20-30 parts of sweet corn protein powder, 8-14 parts of corn germ meal, 2-10 parts of bean pulp, 10-30 parts of fermented bioprotein, 5-15 parts of black sesame powder, 8-14 parts of bloodworms, 0.5-3 parts of aloe powder, 0.5-3 parts of lotus leaf powder, 0.1-0.8 parts of cerium citrate, 1-3 parts of methionine, 1-3 parts of threonine, 0.01-0.07 parts of a complex enzyme, 0.01-0.09 parts of microelements, 1-3 parts of Chinese herbal medicines, 2-10 parts of an attractant and 0.5-1.5 parts of multivitamins. With the adoption of the special feed, even if under the condition of manual high-density culture, the fatality rate of the mandarin fish fries is very low, the feed is good in palatability and high in nutritional value, the ratio is reasonable, the cost is low, and fish is delicious.

The invention discloses a polymorphism site genetype of MTHFR gene to predict individual cardiovascular disease and prognostic application in the medical domain, which detects polymorphism parting oligonucleotide of MTHFR gene and polymorphism site genetype through MTHFR gene to predict the individual cardiovascular disease and prognostic method and agent box.

The invention discloses special feed for 50-150-day old mandarin fish. The special feed comprises raw materials in parts by weight as follows: 40-80 parts of fish meal, 50-120 parts of krill meal, 30-50 parts of sandworm powder, 10-12 parts of cod liver oil, 0.5-2.5 parts of palm oil, 1.5-3.5 parts of corn oil, 5-18 parts of scallop skirts, 5-18 parts of sweet corn gluten meal, 10-16 parts of maize germ oil, 5-15 parts of cottonseed cakes, 10-18 parts of fermented bioprotein, 8-17 parts of black sesame powder, 10-38 parts of blood worms, 1-3 parts of radix aucklandiae, 1-3 parts of taurine, 0.5-1.5 parts of probiotics, 0.5-1.2 parts of methionine, 0.2-0.8 parts of threonine, 0.05-0.09 parts of compound enzyme, 0.01-0.03 parts of microelements, 2-5 parts of Chinese herbal medicines, 5-10 parts of a phagostimulant and 1-3 parts of vitamins. The product is used for the 50-150-day old mandarin fish, stress caused during feed changing can be reduced, transition between different kinds of feed is facilitated, the feed has good palatability and high nutritional value and is low in cost, the mandarin fish can grow fast if the mandarin fish is fed on the feed, and the fatality rate is small.

The invention relates to a coding amino acid sequence of an armed chimeric antigen receptor capable of specifically knocking out and targeting the SARS-CoV-2 virus SPIKE protein constructed by SARS-CoV-2 virus RNA polymerase, an immune response cell modified by the amino acid sequence, preparation methods and applications. The recombinant vector of the armed chimeric antigen receptor targeting theSARS-CoV-2 virus SPIKE can be constructed by knocking out the SARS-CoV-2 virus RNA polymerase, and a method using the recombinant vector to modify the immune response cell is also constructed; and the obtained novel functional immune response cell can effectively target and attack various viruses. The preparation method of the immune response cell modified by the armed chimeric antigen receptor targeting the SARS-CoV-2 virus SPIKE is simple in step; and the obtained immune response cell targeting the virus SPIKE and modified by virus replication-dependent RNA polymerase has obvious killing effects on coronavirus.

The invention belongs to the field of biology, and particularly relates to an early diagnosis reagent for colorectal cancer based on combined detection of methylation levels of a SDC2 gene and a SFRP2gene. The early diagnosis reagent is characterized in that the excrement is used as a detection sample, the SDC2 gene and the SFRP2 gene are jointly used as biological markers, and the methylation levels of the SDC2 gene and the SFRP2 gene are detected. Proofed by results, the early diagnosis reagent has the advantages that the detected methylation levels of the SDC2 gene and the SFRP2 gene in the excrement are highly related with the disease generation of colorectal cancer, the detection sensitivity of colorectal cancer is 94.74%, and the specificity is 96.67%; the detection result is accurate, quick and simple, and the non-wound type colorectal cancer screening and early diagnosis are realized.

The invention discloses environment-friendly and pollution-free feed for longsnout catfish. The environment-friendly and pollution-free feed comprises raw materials in parts by weight as follows: 45-65 parts of fish meal, 20-30 parts of shrimps, 15-45 parts of sargassum, 2-10 parts of fish oil, 1-5 parts of corn oil, 15-25 parts of bean pulp, 10-18 parts of rapeseed meal, 10-18 parts of high-gluten flour, 5-15 parts of corn flour, 2-10 parts of wheat bran, 5-15 parts of puffed sweet potato flour, 0.2-0.8 parts of glycine betaine, 8-15 parts of an EM (effective microorganism) bacterium liquid, 1-5 parts of soybean phospholipid and 8-16 parts of premix. The feed is prepared with the process as follows: fish meal, shrimps, sargassum, the bean pulp, the rapeseed meal, the high-gluten flour, the corn flour, the wheat bran and the puffed sweet potato flour are crushed and stirred in the proportion, the fish oil, the corn oil, the glycine betaine, the EM bacterium liquid, the soybean phospholipid and the premix are stirred continuously, water is added until the water content of the system is 20wt%-40wt%, steam is introduced for curing, granulating and cooling are performed, and the environment-friendly and pollution-free feed for the longsnout catfish is prepared. The feed is non-toxic, harmless and environment-friendly and cannot cause pollution to people, the longsnout catfish and water areas where the longsnout catfish live, the fatality rate of the longsnout catfish is low, and the growth speed is high.

A method for raising quails for eggs using internal and external ecological technology discloses a method for ecologically raising quails for eggs, which uses natural organic disinfectants instead of daily disinfectants to improve the internal and external environment of quail houses and make the air quality comply with NY/T391 ( Environmental technical conditions for green food production areas) requirements; adding lactic acid bacteria to the quail feed for eggs instead of medicine and health care can regulate the normal flora of the gastrointestinal tract of the egg quail body, maintain the micro-ecological balance, and inhibit the growth and reproduction of spoilage bacteria and the production of spoilage products in the intestinal tract. Effectively reduce harmful gases such as ammonia in quail houses and the odor of feces, improve the breeding environment, and improve the health of laying quails; establish a reasonable immunization program through pathogen investigation and antibody detection to control the occurrence of diseases. After adopting the method, the internal and external environment of the poultry house is greatly improved, the resistance of laying quail to diseases and the prevention of infectious diseases are enhanced, the occurrence of epidemic diseases is controlled, the yield of quail eggs is increased, and the quality of quail eggs is improved.

The invention provides a traditional Chinese medicine composition and application thereof in prevention and treatment of viral pneumonia. According to the traditional Chinese medicine composition, 40-130 parts of fructus forsythiae, edible tulip, honeysuckle, scutellaria baicalensis and folium isatidis are used as basic components, and 50-110 parts of a qi-tonifying yin-nourishing component, 20-50parts of a spleen-tonifying circulation-assisting component, 15-50 parts of a phlegm-heat-clearing component, 14-50 parts of a phlegm-eliminating masses-resolving component and 20-50 parts of a lung-promoting, lung-moistening, lung-astringing and asthma-preventing component which accord with incompatibility of traditional Chinese medicines are matched. The traditional Chinese medicine compositionhas the effects of clearing away heat and toxic materials, dispelling wind and promoting exterior syndrome, relieving cough and reducing sputum and tonifying qi and yin, is suitable for treating thenovel coronavirus pneumonia, can effectively relieve symptoms of patients with the novel coronavirus pneumonia and improve prognosis, reduces the diseaseseverity-causing rate and the case fatality rate, and is clear and remarkable in curative effect.

The invention discloses green and healthy feed with the good fattening effect for a fattening period of sheep. The feed comprises raw materials in parts by weight as follows: 20-40 parts of cooked peanut cakes, 15-35 parts of corn, 20-36 parts of corn germ meal, 20-40 parts of wheat, 15-35 parts of fermented sesame cakes, 2-10 parts of grass meal, 8-16 parts of chrysanthemum meal, 5-15 parts of silkworm chrysalis meal, 10-20 parts of bone meal, 8-13 parts of brewer's grains, 10-25 parts of fermentation protein, 0.002-0.006 parts of tryptophan, 0.005-0.009 parts of lysine, 0.005-0.0085 parts of methionine, 0.007-0.0095 parts of threonine, 0.004-0.008 parts of glutamic acid, 1-3 parts of a Chinese herbal medicine additive and 2-7 parts of an attractant. The feed is green, healthy and balanced in nutrition and has the good fattening effect.

The invention provides a primer pair for detecting novel coronavirus SARS-CoV-2, a probe, a composition, a kit and an application thereof. The fluorescent RT-RAA primer and the fluorescent probe can be used for rapidly and qualitatively detecting the novel coronavirus SARS-CoV-2 in a patient sample. According to the fluorescent RT-RAA primer and the fluorescent probe provided by the invention, when the fluorescent RT-RAA primer and the fluorescent probe are used for detecting the novel coronavirus SARS-CoV-2, the detection time is remarkably shortened compared with a PCR method or fluorescentPCR, and the sensitivity is equivalent to or even higher than that of the fluorescent PCR.

The invention discloses a traditional Chinese medicine composition for treating acute stroke and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw medicines: senna leaf, giant knotweed rhizome, artificial bovine calculus powder, concretio silicea bambusae and trichosanthes fruit seed. The traditional Chinese medicine composition provided by the invention has the efficacy of dredging intestines and inducing resuscitation, is suitable for the symptoms of viscera and phlegm retention and viscera qi obstruction caused by the acute stroke, and is used for treating phlegm retention and viscera qi obstruction of yang and yin shutting syndromes of viscera caused by the stroke. The traditional Chinese medicine composition for treating patients suffering from acute stroke can improve clinical curative effect, reduce mortality and improve the life quality of patients; and the clinical application is safe without side effects.

The invention builds a blood serum protein mass spectrometric model that is used for detecting multiple myeloma, finds out that the blood serum protein of multiple myeloma patients has 56 characteristic proteins, chooses any two or over two proteins from the 56 characteristic proteins, and uses mass spectrometric analysis, thus detecting diseases including the multiple myeloma. According to the mass spectrometric model, the invention develops a reagent and a kit that are used for detecting the characteristic proteins in a biological sample through a mass spectrometric method.