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77 results about "Polyallylamine hydrochloride" patented technology
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Polyallylamine hydrochloride (CAS No. 71550-12-4) is a cationic polyelectrolyte prepared by the polymerization of allylamine. It can be used in combination with an anionic polyelectrolyte like poly(sodium styrene sulfonate) to form a layer-by-layer adsorbed film of negatively and positively charged polymers. Poly(allylamine hydrochloride) has many biomedical applications. The most prominent use of this polyelectrolyte is in the field of cell encapsulation. A layer by layer method is used by alternating positively and negatively charged polyelectrolytes to build a barrier between the cell and the harsher outside environment. Upon cell lysis, the capsule of layered polyelectrolytes maintains its structural integrity and can be used for purposes such as drug delivery.
Method for preparing protamine and dextran sulfate sodium microcapsule
InactiveCN101530767AGood size controlBiocompatibleMicroballoon preparationMicrocapsule preparationMultilayer membraneMicrosphere
The invention relates to a method for preparing the protamine and dextran sulfate sodium microcapsule, comprising the following steps: reacting calcium chloride, sodium carbonate, sodium polystyrene sulfonate or polyallylamine hydrochloride, cetyl trimethyl ammonium bromide, PEO20-PPO70-PEO20 triblock copolymer, polydiallyldimethylamine chloride solution with stirring at the temperature of 10 to 80 DEG C to obtain the calcium carbonate microsphere; fully mixing the obtained calcium carbonate microsphere with the protamine water solution, adsorbing the protamine, removing the protamine not to be adsorbed, fully mixing the calcium carbonate microsphere with the protamine withdextran sulfate sodium containing inorganic salt to adsorb dextran sulfate sodium, removing the dextran sulfate sodium not to be adsorbed; alternately adsorbing to obtain the microcapsule with the protamine and dextran sulfate sodium multilayer membrane core-shell structure; dissolving calcium carbonate in ethylenediaminetetraacetic acid sodiumsalt to obtain the protamine and dextran sulfate sodium microcapsule.
Owner:NINGBO UNIVERSITY OF TECHNOLOGY
Preparation method of layered Li4Ti5O12@graphene composite lithium ion battery anode material
InactiveCN104103823AHigh charge and discharge capacityImprove conductivityCell electrodesSecondary cellsUltrasonic dispersionHydrogen peroxide
The invention relates to a preparation method of a layered Li4Ti5O12@graphene composite lithium ion battery anode material, which comprises the following steps: 0.640-0.690 g of lithium hydroxide monohydrate, 1,8-2.2 ml of hydrogen peroxide and 1.32-1.40 g of tetrabutyl titanate are added into deionized water and stirred to enable the solution to be transparent, the mixed solution is subjected to the hydro-thermal reaction, the temperature of the mixed solution is reduced to the room temperature through natural cooling, and centrifugal separation, washing and drying are carried out to obtain milk white Li4Ti5O12 powder; high temperature annealing is performed on the milk white Li4Ti5O12 powder in air for 3.8-4.2 hours at 500 DEG C to obtain pure white Li4Ti5O12 powder; 10-12 mg of the pure white Li4Ti5O12 powder is added into a 1g / L poly(allylamine hydrochloride) solution, subjected to ultrasonic dispersion and then dispersed into 30 ml of 0.2g / L GO solution, strong stirring is carried out at 0 DEG C, 20 ml of 80 wt% hydrazine hydrate solution is added, the mixed solution is heated to be 98 DEG C for 50-70 minutes, and the obtained sample is washed, filtered, and dried in vacuum to obtain the black Li4Ti5O12@graphene powder. According to the invention, the surfaces of dandelion-shaped Li4Ti5O12 microspheres are coated with a layer of ultrathin graphene to prepare the layered Li4Ti5O12@graphene composite lithium ion battery anode material, so that the charge-discharge capacity and the cycle life of the lithium ion battery anode material are improved.
Owner:TONGJI UNIV
Silk fibroin/manganese dioxide composite micro-sphere drug carrier with core-shell structure and preparation method
ActiveCN110251480AGood dispersionLarge specific surface areaOrganic active ingredientsEnergy modified materialsManganeseOxygen
The invention discloses a preparation method of a silk fibroin / manganese dioxide composite micro-sphere drug carrier with a core-shell structure. The preparation method includes the steps: (1) adding aqueous-organic solvents into silk fibroin water solution, removing the solvents after freezing-natural thawing to obtain a silk fibroin nanosphere; (2) uniformly mixing the obtained silk fibroin nanosphere, potassium permanganate and polyallylamine hydrochloride, finishing incubation and removing the solvents to obtain the silk fibroin / manganese dioxide composite micro-sphere drug carrier with the core-shell structure taking silk fibroin as an inner layer and manganese dioxide as an outer layer. The preparation method is simple in process and simple and convenient in operation, the surface of a prepared silk fibroin / manganese dioxide composite micro-sphere is rough, excellent performances of the silk fibroin and the manganese dioxide are combined, drug loading rate is high, the preparation method can respond to controllable release of tumor microenvironments, hydrogen peroxide in a tumor environment is degraded to generate oxygen, chemical and photodynamic therapy efficiency of tumors is improved, and the preparation method has a wide application prospect in the field of tumor therapy and drugs.
Owner:ZHEJIANG UNIV
Reagent and method for measuring thrombin-antithrombin complex
ActiveUS20180238871A1Small amountAccurate measurementDisease diagnosisBiological testingDextranAmmonium chloride mixture
Owner:MITSUBISHI CHEM MEDIENCE
Method of preparing linoleate isomerase micro-capsules on the basis of polyelectrolyte layer-by-layer self-assembly technology
InactiveCN104974996AControllable wall thicknessIncrease the areaOn/in organic carrierHalf-lifeAmorphous calcium carbonate
The invention provides a method of preparing linoleate isomerase micro-capsules on the basis of a polyelectrolyte layer-by-layer self-assembly technology and can solve a problem that free linoleate isomerase is poor in tolerance, is poor in stability and cannot be recycled in industrial production. The method of the invention includes the following steps: with an amorphous calcium carbonate crystal, which is obtained through co-precipitation of calcium carbonate and the linoleate isomerase, as a template and with polyallylamine hydrochloride and sodium polystyrenesulfonate as coating materials, preparing the linoleate isomerase micro-capsules through the polyelectrolyte layer-by-layer self-assembly technology. The micro-capsule is high in activity, excellent in stability and long in half life.
Owner:INNER MONGOLIA AGRICULTURAL UNIVERSITY
Self-repairing corrosion inhibitor of Q235 steel and preparing method thereof
InactiveCN109468645AAchieve releaseImprove anti-corrosion performanceCathode reactionPolyallylamine hydrochloride
The invention discloses a pH-sensitive Q235 steel corrosion inhibitor with the self-healing ability. The corrosion inhibitor is 8-HQ embedded HNTs, the outer portion is wrapped with a polyelectrolyte,and the polyelectrolyte selects PSS and PAH. When the Q235 steel has the cathode reaction in the corrosion process, the local pH value is changed, the 8-HQ is released to form a complex compound withiron ions, and absorbing is carried out on the surface of the Q235 steel so as to overcome the defect.
Owner:SHANGHAI NORMAL UNIVERSITY
Lithium ion battery silicon-carbon negative electrode binder, and negative electrode sheet and preparation method thereof
ActiveCN112038633AOptimize the drying processReduces total drying timeElectrode thermal treatmentSecondary cellsPhysical chemistryALLYL SUCROSE
The invention relates to the technical field of lithium ion batteries, provides a lithium ion battery silicon-carbon negative electrode binder, and a negative electrode sheet and a preparation methodthereof, and aims to solve the problems of uneven distribution of a binder in the longitudinal direction of an electrode sheet, reduction of the adhesive force of a coating layer and high production cost easily caused by a traditional negative electrode coating and baking process. The lithium ion battery silicon-carbon negative electrode binder is selected from one or a combination of two of polyallylamine hydrochloride and polyacrylic acid polybenzimidazole. According to the invention, by adopting the novel polymer binder and optimizing the electrode sheet drying process, the migration of thebinder in the electrode sheet is effectively inhibited, the longitudinal distribution uniformity of the binder in the negative electrode sheet is improved, the battery performance is improved, the electrode sheet baking time is shortened, and the battery manufacturing cost is reduced.
Owner:WANXIANG 123 CO LTD
Phthalocyanine-polyoxometallate third-order nonlinear optical self-assembled film and preparation method thereof
InactiveCN103991257APacked tightlyImprove stabilityFibre treatmentSynthetic resin layered productsPhthalocyanineLayer by layer self assembly
The invention discloses a phthalocyanine-polyoxometallate third-order nonlinear optical self-assembled film and a preparation method of the phthalocyanine-polyoxometallate third-order nonlinear optical self-assembled film and belongs to the technical field of preparation of function materials. The self-assembled film has third-order nonlinear optical properties including self-defocusing and saturated absorption under a nanosecond laser condition and comprises a substrate, a precursor film and an alternative deposition layer from bottom to top, wherein the precursor film is formed by the alternating deposition of polyallylamine hydrochloride layers and polystyrene sulfonate layers, the bottommost layer of the precursor film is the polystyrene sulfonate layer and is connected with the substrate, and the uppermost layer of the precursor film is the polystyrene sulfonate layer and is connected with the alternative deposition layer; the alternative deposition layer is formed by the alternating deposition of a polyoxometallate layer and a phthalocyanine layer, and the bottommost layer of the alternative deposition layer is the polyoxometallate layer. According to the preparation method, the phthalocyanine-polyoxometallate third-order nonlinear optical self-assembled film is obtained by carrying out alternative assembling in a non-aqueous solvent by virtue of a layer-by layer-self-assembly method and has high stability and the excellent nonlinear optical properties.
Owner:BEIJING UNIV OF CHEM TECH
Tacrolimus nanocrystal and artificial tear compound and preparation method thereof
ActiveCN108383856AChange hydrophobicityImprove solubilityOrganic active ingredientsSenses disorderHigh concentrationLubrication
The invention discloses a tacrolimus nanocrystal and an artificial tear compound and preparation method thereof. Tacrolimus is a nanocrystal. The tacrolimus nanocrystal is prepared through a recrystallization method. The artificial tear compound of the tacrolimus nanocrystal comprises a nanocrystal of tacrolimus as a core and a shell layer covering the core; the shell layer comprises a plurality of double layers, and each double layer comprises a sodium carboxymethyl cellulose layer and a cationic polymer layer from inside to outside in sequence; a cationic polymer is at least one of polyallylamine hydrochloride, polylysine and polyethyleneimine. The compound is prepared by a layer-by-layer self-assembling method. The tacrolimus nanocrystal as hydrophilicity, high bioavailability and low toxicity, and the artificial tear compound of the tacrolimus nanocrystal has the effects of reducing direct stimulation of high-concentration medicine and exerting immunomodulatory anti-inflammatory and lubrication synergy. The tacrolimus nanocrystal and the artificial tear compound and preparation method thereof can be applied to preparation of medicine for treatment of ocular diseases.
Owner:INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI +1
Oil-repellent and water-absorbent palygorskite-double-network gel sponge as well as preparation method and application thereof
ActiveCN113698659AAvoid re-entryAvoid enteringOther chemical processesGeneral water supply conservationPotassium persulfateMeth-
The invention discloses oil-repellent and water-absorbent palygorskite-dual-network gel sponge and a preparation method and application thereof. The preparation method comprises the steps: mixing a polyallylamine hydrochloride solution and a palygorskite dispersion liquid, and performing centrifugal drying treatment to obtain polyallylamine modified palygorskite powder; uniformly dispersing the polyallylamine modified palygorskite powder in water to obtain a polyallylamine modified palygorskite dispersion liquid; mixing the polyacrylamide modified palygorskite dispersion liquid with a sodium perfluorooctanoate solution for reaction, and performing centrifugal drying treatment to obtain modified palygorskite powder; uniformly dispersing the modified palygorskite powder in water to obtain a modified palygorskite dispersion liquid; adding acrylamide and sodium alginate into the modified palygorskite dispersion liquid, dissolving, adding potassium persulfate and N,N'-methylene dilactam, dissolving, adding tetramethylethylenediamine, and stirring until the solution is converted into gel; and soaking the gel in a calcium chloride solution, and performing freeze drying treatment to obtain the palygorskite-double-network gel sponge. According to the sponge, purification treatment of oil substances can be realized.
Owner:XI AN JIAOTONG UNIV
Wear-resistant and anti-aging waterborne glazing oil and preparation method thereof
InactiveCN110079179AReduce contact areaImprove hydrophilicityCoatingsPotassium persulfateWear resistant
The invention discloses wear-resistant and anti-aging waterborne glazing oil and a preparation method thereof, and relates to the field of novel environment-friendly high polymer materials. The preparation method comprises steps as follows: PAH-D microgel is prepared from polyacrylamide hydrochloride, glucan and metal powder together, pretreated tetratitanate is soaked with a PAH-D microgel dispersion liquid and a poly 4-vinylbenzenesulfinic acid sodium salt solution respectively, and an additive is prepared; acrylic resin is mixed with a mixed surfactant, potassium persulfate and water are added, after a stirring reaction is performed, styrene, butyl acrylate and ammonium hydroxide are added, a blank is prepared by a mixing reaction, finally, the blank is mixed with silicone oil, the additive is added, and the wear-resistant and anti-aging waterborne glazing oil is prepared. The prepared wear-resistant and anti-aging waterborne glazing oil has excellent wear resistance and oxidation resistance.
Owner:江苏美乔科技有限公司
Nano-material composite membrane for water treatment and preparation method thereof
ActiveCN111013555AGood dispersionImprove adsorption capacityMembranesWater/sewage treatment by irradiationModified carbonDiethylenetriamine
The invention discloses a nano-material composite membrane for water treatment and a preparation method thereof, belonging to the technical field of sewage treatment. The preparation method comprisesthe following steps: firstly, oxidizing glucan with potassium periodate to prepare oxidized glucan, and then treating carbon nanotubes by using polyacrylic acid and diethylenetriamine to prepare modified carbon nanotubes; secondly, mixing and reacting oxidized glucan with polyallylamine hydrochloride and the modified carbon nanotubes to prepare a micro-gel; mixing the micro-gel with tetrabutyl titanate, and carrying out hydrolyzing and filtering to obtain a modified micro-gel; mixing the modified micro-gel with polyvinylidene fluoride and polyvinylpyrrolidone to obtain a film forming solution;and forming a film on a glass plate by using the film forming solution, uncovering the film, and carrying out washing and drying to obtain the nano-material composite membrane for water treatment. The water treatment nano-material composite membrane prepared by the method has good treatment capacity on water polluted by metal ions and organic matters.
Owner:胡小青
Removable Tattoo Ink and the Use Thereof
InactiveUS20150265508A1Easy to disassembleCosmetic preparationsMake-upTattoo inkPolyallylamine hydrochloride
Provided is a removable tattoo ink that is composed of colored micro-particles that create permanent tissue markings, such as tattoos. The micro-particles include an inner core housing a bio-absorbable chromophore and an outer shell, which includes polystyrene sulfonate and polyallylamine hydrochloride and is designed for rupture with ultrasonic energy. The micro-particles can be implanted in the tissue of a subject, for example to create a tattoo and ruptured in situ by the application of ultrasonic energy to remove the tattoo. Also provided are methods of making the colored micro-particles.
Owner:ULTRA INK
Low salt forms of polyallylamine
InactiveUS7541024B2Reduce phosphate serum levelLess anionMetabolism disorderUrinary disorderDiluentChloride
Disclosed is a pharmaceutical composition comprising a stable polyallylamine hydrochloride polymer in which between about 4% to about 12% by weight of the polymer is a chloride anion and a pharmaceutically acceptable carrier or diluent.
Owner:GENZYME CORP
Biomass based composite material with high degradability for non-woven fabric and processing technology of biomass based composite material
ActiveCN110129918AReduce joinGood flexibilityConjugated synthetic polymer artificial filamentsArtifical filament manufactureNonwoven fabricBiodegradable polymer
The invention discloses a biomass based composite material with high degradability for non-woven fabric and a processing technology of the biomass based composite material, and belongs to the technical field of biodegradable polymer composite materials. The processing technology comprises steps as follows: after sodium alginate and nano-silica are mixed, the mixture is processed by a silane coupling agent KH-550, and modified sodium alginate is prepared; then, oxidized starch and polyallylamine hydrochloride are subjected to a mixed reaction, the modified sodium alginate is added, a stirring reaction is performed, and an additive is prepared; polylactic acid and epoxidized soybean oil are mixed, a catalyst and the additive are added, mixed banburying and pelletizing are performed, and thebiomass based composite material with high degradability for the non-woven fabric is obtained. The biomass based composite material with high degradability for the non-woven fabric has better heat resistance, excellent flexibility and higher degradability and is suitable for preparing the non-woven fabric.
Owner:山东莱芬无纺布有限公司
Electrochemical biosensor, preparation method thereof and method for detecting novel coronavirus
PendingCN113777141AReduce volumeEasy to carryMaterial electrochemical variablesAgainst vector-borne diseasesElectrochemical biosensorFerrocene
The invention relates to the field of electrochemical analysis and detection, and discloses an electrochemical biosensor, a preparation method thereof and a method for detecting novel coronavirus. The electrochemical biosensor provided by the invention comprises a screen-printed electrode and a functional layer modified on the surface of the screen-printed electrode, wherein the functional layer contains polyallylamine hydrochloride, cerium dioxide and ferrocene-labeled non-specific single-stranded DNA. The preparation method of the electrochemical biosensor comprises the following steps of dispensing a modification solution containing polyallylamine hydrochloride, cerium dioxide and ferrocene-labeled non-specific single-stranded DNA on the surface of a screen-printed electrode, and drying to form a functional layer on the surface of the screen-printed electrode. The electrochemical biosensor provided by the invention can realize rapid and high-sensitivity detection of novel coronavirus.
Owner:NANJING NORMAL UNIVERSITY
Preparation method of sevelamer carbonate
InactiveCN103864972AMeet the requirementsGood molding effectMetabolism disorderPhosphoric acidRoom temperature
The invention discloses a preparation method of sevelamer carbonate. The preparation method comprises the steps: dissolving polyallylamine hydrochloride with the average molecular weight of 8000-20000 in water, adding sodium hydroxide, then cooling to the room temperature, adding epoxy chloropropane, stirring until being viscous, and placing for 18-24 hours at the room temperature, wherein the weight part ratio of polyallylamine hydrochloride, sodium hydroxide and epoxy chloropropane is 1:0.2-0.8:0.2-0.8. Experimental results show that when the molecular weight of polyallylamine hydrochloride is in a range of 8000-20000, preferably in a range of 10000-15000, the prepared sevelamer carbonate has the advantages of good formability of tablets, high hardness and easy coating, moreover, has the disintegration time less than 3 minutes, can be fully mixed with food, reaches an effect of full complexation of phosphoric acid, and is more beneficial for patients to use.
Owner:TIANJIN TAIPU PHARMA SCI & TECH DEV
Preparation process of sevelamer carbonate
InactiveCN105732865AAvoid wastingThe amount added is accurateOrganic active ingredientsMetabolism disorderSevelamerCarbonate
The invention relates to the technical field of production of sevelamer carbonate. A preparation process of sevelamer carbonate comprises the steps as follows: firstly, an epichlorohydrin acetonitrile solution is added to a poly (allylamine hydrochloride) solution in proportion, curing is performed, and polymerized jelly is obtained; after polymerization, the jelly is milled to 50 meshes by a colloid mill, then a 4% sodium hydroxide aqueous solution is added, the stirring reaction is performed, and sevelamer alkali is obtained; finally, purified water is added to the sevelamer alkali, then the temperature is raised, carbon dioxide is fed in, centrifugation and drying are preformed after heat-preserved stirring reaction, and sevelamer carbonate is obtained. By adopting the preparation process of sevelamer carbonate, the product energy consumption can be greatly lowered, the product quality is improved, and the problem of production of waste water is solved; meanwhile, the labor intensity can also be reduced, and the labor productivity is raised; the product quality is improved, the qualified rate of finished products reaches 99.6%, and the yield reaches 64.7%.
Owner:JIANGSU TIANHE PHARMA CO LTD
Low Salt Forms of Polyallylamine
InactiveUS20100068167A1Reduce phosphate serum levelLess anionMetabolism disorderUrinary disorderDiluentChloride
Disclosed is a pharmaceutical composition comprising a stable polyallylamine hydrochloride polymer in which between about 4% to about 12% by weight of the polymer is a chloride anion and a pharmaceutically acceptable carrier or diluent.
Owner:GENZYME CORP
Preparation method of polyallylamine hydrochloride polymer
Owner:CHANGZHOU FANGYUAN PHARMA
Compound water retention additive for meat food and preparing method of compound water retention additive
InactiveCN110150367AGreat tasteImprove water retentionSugar food ingredientsInorganic compound food ingredientsFood additiveMonopotassium phosphate
The invention discloses a compound water retention additive for meat food and a preparing method of the compound water retention additive, and belongs to the technical field of food additives. A microcapsule is prepared from polyallamine hydrochloride and aldehyde dextran, calcium peroxide and ferrous chloride tetrahydrate react and are added into the microcapsule, the additive is prepared, the additive is mixed with sodium tripolyphosphate, sodium pyrophosphate, monopotassium phosphate, sodium hexametaphosphate, trisodium phosphate and glucose are added to be stirred and mixed, and the compound water retention additive for meat food is prepared. The prepared compound water retention additive for meat food has excellent water retention performance.
Owner:江苏成琦生物集团有限公司
Preparation method of three-dimensional porous Rh-Ir alloy dendritic crystal nanoflower as well as material obtained by preparation method and application of three-dimensional porous Rh-Ir alloy dendritic crystal nanoflower
ActiveCN111600040ANot easy to aggregate and dissolveEasy transferMaterial nanotechnologyCell electrodesIridiumPtru catalyst
The invention discloses a preparation method of a three-dimensional porous Rh-Ir alloy dendritic crystal nanoflower, as well as a material obtained by the preparation method and the application of thematerial as a hydrogen evolution catalyst. The method comprises the following steps that polyallylamine serves as a morphology regulating agent, rhodium salt and iridium salt serve as precursors, ethylene glycol and polyallylamine hydrochloride are mixed to be uniform, then a precursor solution of rhodium and iridium is added, and the three-dimensional porous Rh-Ir alloy dendritic crystal nanoflower is obtained through hydrothermal method reduction. Compared with the traditional preparation method, the method provided by the invention is simple in process operation and easy to synthesize, thedeionized water can be used for removing heteroions and excess morphology regulating agent in the solution, and the excess morphology regulating agent is a recyclable green chemical reagent, so thatthe method is environment-friendly and pollution-free. The three-dimensional porous Rh-Ir alloy dendritic crystal nanoflower prepared through the method is not larger than 60 nm in diameter, single inmorphology and extremely high in purity, has the advantages of being large in specific surface area, multiple in active sites, good in electron conductivity, stable in structure and the like, and shows excellent electro-catalytic activity on hydrogen evolution.
Owner:NANJING NORMAL UNIVERSITY
Bacterium and MOF-based carrier hybrid material as well as preparation method and application thereof
ActiveCN113350514AHigh suppression efficiencyImproving the effect of targeted tumor therapyOrganic active ingredientsEnergy modified materialsShewanella oneidensisCombined treatment
The invention discloses a bacterium and MOF-based carrier hybrid material as well as a preparation method and application thereof, and the method comprises the following steps: loading a therapeutic agent on MOF nanoparticles to obtain a chemotherapeutic drug loaded MOF carrier; wrapping hyaluronic acid on the MOF carrier loaded with the chemotherapeutic drug to obtain an MOF carrier with electronegative surface; modifying the surface of shewanella with polyallylamine hydrochloride to obtain a shewanella solution with electropositive surface; and combining the MOF carrier with electronegative surface and the shewanella solution with electropositive surface through electrostatic interaction to obtain the bacterium and MOF-based carrier hybrid material. The bacterium and MOF-based carrier hybrid material is high in accuracy in anti-tumor treatment, can be used for multi-mode combined treatment, not only combines the advantages of each single therapy, but also can make up the respective defects, thereby generating an efficient and low-toxicity anti-tumor effect.
Owner:WUHAN UNIV +1
Tacrolimus nanocrystal and its artificial tear compound and preparation method
ActiveCN108383856BChange hydrophobicityImprove solubilityOrganic active ingredientsSenses disorderDiseaseCellulose
The invention discloses a tacrolimus nanocrystal and an artificial tear compound and preparation method thereof. Tacrolimus is a nanocrystal. The tacrolimus nanocrystal is prepared through a recrystallization method. The artificial tear compound of the tacrolimus nanocrystal comprises a nanocrystal of tacrolimus as a core and a shell layer covering the core; the shell layer comprises a plurality of double layers, and each double layer comprises a sodium carboxymethyl cellulose layer and a cationic polymer layer from inside to outside in sequence; a cationic polymer is at least one of polyallylamine hydrochloride, polylysine and polyethyleneimine. The compound is prepared by a layer-by-layer self-assembling method. The tacrolimus nanocrystal as hydrophilicity, high bioavailability and low toxicity, and the artificial tear compound of the tacrolimus nanocrystal has the effects of reducing direct stimulation of high-concentration medicine and exerting immunomodulatory anti-inflammatory and lubrication synergy. The tacrolimus nanocrystal and the artificial tear compound and preparation method thereof can be applied to preparation of medicine for treatment of ocular diseases.
Owner:INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI +1
Heat-shrinkage-resistant sealing ring and preparation method thereof
InactiveCN111117121AImproved resistance to heat shrinkageImprove mechanical propertiesFibre typesFiberPolymer science
The invention provides a heat-shrinkage-resistant sealing ring and a preparation method thereof. Fluoroether rubber and polyacrylate rubber are adopted as main materials and have excellent high-temperature resistance and aging resistance, so that the sealing ring has good high-temperature resistance, and it can be guaranteed that the sealing ring still has good mechanical properties after being subjected to high-temperature treatment; sodium gluconate can improve the size stability of the sealing ring; a modified fiber is used for improving the dimensional stability of the sealing ring and improving the shrinkage resistance of the sealing ring; double-vinyl-terminated silicone oil is used for improving the toughness of the rubber and improving the sealing performance of the sealing ring; and polyallylamine hydrochloride can improve the mechanical stability of the sealing ring, so that the sealing ring has excellent shrinkage resistance. Experimental results show that the heat-resistantand oil-resistant sealing ring has excellent shrinkage resistance, mechanical properties and the like. The preparation method is simple, and the prepared heat-shrinkage-resistant sealing ring has excellent heat shrinkage resistance and mechanical properties.
Owner:河北新尔特橡塑密封有限公司
Drugs and Food Products for Hypophosphoric Normo-,Hyper-and Hypoproteic Diets, and Hypophosphoric Beverages
InactiveUS20090306013A1Reduce riskIncrease the number ofOrganic active ingredientsHeavy metal active ingredientsAluminium hydroxideNuclear chemistry
The present invention relates to an alimentary component comprising a physiologically acceptable phosphorus binding agent, in particular polyallylamine hydrochloride, polyallylamine carbonate, lanthanum carbonate, aluminium hydroxide, magnesium acetate, magnesium carbonate, calcium carbonate, calcium acetate, calcium citrate, calcium alginate, styrene divinyl-benzene ionic exchange resin, stabilized polynuclear iron hydroxide, calcium acetate plus magnesium carbonate and chitosan. Said component is useful in the nutrition of subjects in need of a low phosphorus level diet.
Owner:SAVICA VINCENZO
Process of preparing polycrystalline nanotube of metal oxide
InactiveCN100569655CGood removal effectIncrease productionNanostructure manufactureOxide/hydroxide preparationUltrasonic dispersionPolypropylene
The method for preparing metal oxide polycrystalline nanotubes disclosed in the present invention has the following steps: 1) adding multi-walled carbon nanotubes to an aqueous sodium chloride solution, ultrasonically dispersing, and then adding a positively charged polyacrylamine hydrochloride solution , so that polyacrylamine hydrochloride is coated on the surface of the multi-walled carbon nanotubes; 2) The product obtained in step 1) is added to the negatively charged sodium polystyrene sulfonate solution, so that the sodium polystyrene sulfonate is coated Covering the surface of the product in step 1); 3) adding the product obtained in step 2) to a positively charged solution of polyacrylamine hydrochloride, so that polyacrylamine hydrochloride is coated on the surface of the product in step 2); 4) Disperse the product obtained in step 3) in deionized water, add metal chloride, dropwise add sodium borohydride aqueous solution, centrifuge, dry, and heat treatment in an oxygen atmosphere. The invention uses carbon tubes as templates, and can prepare nanotubes of various metal oxides by self-organizing layers of positive and negative charges, and has the advantages of large yield, small particles, fine diameters, and easy removal of templates.
Owner:ZHEJIANG UNIV
Preparation method of electrostatic spinning functional nanofiber film for epidermis repair
ActiveCN113183594AExcellent mechanical propertiesImprove hydrophilicityCosmetic preparationsLamination ancillary operationsFiberPolymer science
The invention discloses a preparation method of an electrostatic spinning functional nanofiber film for epidermis repair, and belongs to the field of medical cosmetology. The preparation method comprises the following steps that: a nanofiber film with polylactic acid caprolactone as a shell layer and polyethylene glycol as a core layer is prepared through coaxial electrostatic spinning; stress is applied to the two ends of the nanofiber film, then unloading is conducted, heated absolute ethyl alcohol is evenly sprayed to the surface of the sample, low-temperature airflow is used for rapidly cooling the nanofiber film, and a winding fiber film is formed; and recombinant human epidermal growth factors are mixed into a sodium polystyrenesulfonate solution to form a negative electricity layer, the winding fiber film is immersed into a polyallylamine hydrochloride solution to form a positive electricity layer, layer-by-layer assembly is carried out, and the multi-layer composite fiber film is formed. The polylactic acid and polycaprolactone copolymer polylactic acid caprolactone serve as the shell layer of the coaxial electrostatically-spun nanofibers, the mechanical property of the fiber film is improved; and the polyethylene glycol serves as the core layer of the fibers, and the hydrophilicity and moisture permeability of the fiber film are improved.
Owner:GUANGDONG UNIV OF TECH
Low-temperature-resistant high-resistance transparent conductive film and preparation method thereof
ActiveCN110534226AAvoid stackingHigh light transmittanceNon-insulated conductorsFinal product manufactureHigh resistanceHigh resistivity
The invention discloses a low-temperature-resistant high-resistance transparent conductive film and a preparation method thereof, and relates to the technical field of transparent conductive thin filmmaterials. According to the invention, graphene oxide is first reduced by dextran to acquire modified graphene; a pretreated silicon wafer is immersed in a polyallylamine hydrochloride solution and an ammonium tetrachlorozincate solution to acquire a modified silicon wafer; the modified silicon wafer and the modified graphene are mixed and react under the action of a reducing agent to prepare a film-bearing silicon wafer; the film is peeled off; and drying is carried out to acquire the low-temperature-resistant high-resistance transparent conductive film. The low-temperature-resistant high-resistance transparent conductive film prepared by the invention has the advantages of good light transmittance and relatively high resistivity, and can be used well under low-temperature conditions.
Owner:乐清市泰博恒电子科技有限公司
Synthesis process of Sevelamer
ActiveCN102675510AImprove adsorption capacitySimple and fast operationMetabolism disorderCross-linkAlcohol
The invention discloses a synthesis process of Sevelamer, particularly provides a new method for synthesising Sevelamer, which is suitable for industrial production, low in cost and simple in operation, wherein the method can be used for producing the hydrochloride or carbonate of Sevelamer, and belongs to the field of medicine synthesis. According to the invention, 1-halo-3-sulfonyloxyl-2-propyl alcohol is used as a cross-linking agent, and reactes with polyene propylamine hydrochloride in an alkaline condition to generate cross-linked polyene propylamine, and the hydrochloride or carbonate of Sevelamer is obtained by process steps such as acidification and salification. Compared with other synthesis methods, the process flow is simple and convenient to operate, the reaction time is shorten by more than 70%, and the phosphorus adsorption capacity of the product is strong and up to 5.0-6..0 mmol / g.
Owner:CHENGDA PHARM CO LTD
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