The invention relates to a synthesis method of isopropanolamine. The synthesis method comprises the following steps: (1)
liquid ammonia and water are mixed to form
ammonia water which is mixed with
propylene oxide;
mixed solution is preheated until the temperature reaches 120 to 125 DEG C, and the inputting
molar ratio of the
ammonia and the
propylene oxide is controlled within 10 to 15; (2) the materiel after preheating is delivered into a reactor, the
reaction temperature ranges from 128 to 138 DEG C, the pressure ranges from 12.6 to 13.8MPa, and the reaction time ranges from 1.5 to 3 hours; (3) the surplus unreacted
ammonia is separated from the obtained mixture after the reaction by using a flash
distillation column, the pressure in the flash
distillation column ranges from 0.6 to 1.6MPa, and the temperature of a column kettle ranges from 140 to 160 DEG C; (4) the mixture which is separated through the flash
distillation column is delivered into a leading
tower for rectification
dehydration, the pressure in the leading
tower ranges from minus 0.080 to minus 0.085MPa, the temperature at the top of the leading
tower is 45 to 55 DEG C, and the temperature at the bottom in a tower kettle ranges from 110 to 130 DEG C; (5) the mixture after
dehydration is delivered into a rectification column for rectification, the pressure in the rectification column ranges from minus 0.095 to minus 0.099MPa, the temperature in the column kettle ranges from 135 to 160 DEG C, the temperature at the top of the rectification column ranges from 60 to 70 DEG C, isopropanolamine products are obtained at the top of the rectification column, and the mixture composed of
diisopropanolamine and
triisopropanolamine is obtained in the column kettle. The synthesis method has simple production procedure, little equipment investment, and high product quality.