147 results about "Agent Combination" patented technology

The use of microfluidic structures enables high throughput screening of protein crystallization. In one embodiment, an integrated combinatoric mixing chip allows for precise metering of reagents to rapidly create a large number of potential crystallization conditions, with possible crystal formations observed on chip. In an alternative embodiment, the microfluidic structures may be utilized to explore phase space conditions of a particular protein crystallizing agent combination, thereby identifying promising conditions and allowing for subsequent focused attempts to obtain crystal growth.

A method for producing a chewing gum, as well as the chewing gum so produced, incorporates a physiological cooling agent, such as acyclic carboxamide, or combinations of physiological cooling agents. In another embodiment a combination of physiological cooling agents is made in a modified release structure. The modified release/cooling agents combination is preferably obtained by physically modifying the properties of the combination of cooling agents by coating and drying. When incorporated into gum, these particles are adapted to enhance the shelf stability of the flavor and/or produce a modified release when the gum is chewed. In another embodiment, the physiological cooling agent is present with menthol and menthone. In another embodiment, coated chewing gum has a coating that comprises a physiological cooling agent. The preferred inventive chewing gum provides a high flavor impact in which the harsh notes normally associated with such a high flavor impact have been reduced or eliminated. In addition, the preferred inventive gum provides a clean, high-quality, cooling chewing gum coating with xylitol or other polyols where xylitol has been reduced in concentration or eliminated.

The invention relates to a ceramic material for 3D light curing formation printing and a preparation method of a ceramic element. The ceramic material is prepared from 30 to 70 vol percent of ceramicpowder and 30 to 70 vol percent of photosensitive resin premixed liquid, wherein the photosensitive resin premixed liquid is prepared from 37 to 50 weight percent of oligomers, 30 to 60 weight percentof reactive diluents, 0.1 to 5 weight percent of photoinitiators, 1 to 5 weight percent of dispersing agents, 0.1 to 0.6 weight percent of ultraviolet blocking agents, 0 to 0.05 weight percent of polymerization inhibitors, 1 to 4 weight percent of anti-foaming agents, 0.5 to 2.35 weight percent of anti-settling agents and 0.3 to 3 weight percent of leveling agents. In the degreasing and sinteringpost-treatment work procedures, specific parameters are used, so that a sintering element can reach good sintering density and mechanical performance. By optimizing the composition and the proportionof light curing ceramic resin, and selecting the excellent dispersing agent combination and the reasonable consumption, the ceramic powder can be better dispersed in the resin; the problems that theexisting light curing ceramic resin has poor flowability and low formation precision, and that a finally prepared ceramic product can easily generate cracks or deformation, and the like are solved.

Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque.

A drug-delivery system is provided including at least 100 μg of everolimus and clobetasol, such that the ratio of everolimus to clobetasol is at least 10:1 (w/w) or the amount of everolimus by weight is at least 10 times more than clobetasol. The system can be a stent. Also provided a method of treating restenosis or vulnerable plaque of a blood vessel, the method includes locally administering to a patient a first drug selected from a group consisting of rapamycin (sirolimus), Biolimus A9, deforolimus, AP23572, tacrolimus, temsirolimus, pimecrolimus, zotarolimus (ABT-578), 40-O-(2-hydroxy)ethylrapamycin (everolimus), 40-O-(3-hydroxy)propylrapamycin, 40-O-[2-(2-hydroxy)ethoxy]ethylrapamycin, 40-O-tetrazolylrapamycin and 40-epi-(N1-tetrazolyl)rapamycin, and locally administering to a patient a second drug consisting of clobetasol, wherein the minimum amount of the first drug that is locally administered is 100 μg, and wherein the ratio of the first drug to the second drug is, for example, 10:1 to 100:1 (w/w).

The invention discloses a polyether modified silicone defoaming agent combination, of which mass fraction is 40-75 of A, 10-55 of B, 0.5-2 of C and 1-5 of D, wherein A and B are the key component, C and D are the secondary component, A is polyether modified silicone defoaming agent, B is defoaming agent of other kinds, C is thickening agent, and D is emulsifying agent. The also discloses the preparation method of the defoaming agent combination. The defoaming agent combination of the invention has the character of polysiloxanes defoaming agent, of which the defoaming capability is high, and surface tension and volatility are low, and which is innocuity, nonpollution and physiologically inert. The defoaming agent combination also has the character of high temperature resistant and alkaliproof like polyethers defoaming agent, and has the advantage of long lasting defoaming agent, defoaming restrain, low incorporaticn and good adaptability. The performance and price ratio is high. It has a better effect when used in stretch thick dope.

The invention relates to a tire having at least one component of a rubber composition comprised of at least one conjugated diene-based elastomer which contains silica reinforcement together with use of a combination of coupling agents for the silica. The coupling agent combination is comprised of blocked alkoxyorganomercaptosilane and unblocked alkoxyorganomercaptosilane coupling agents. Such tire component may be, for example, a tire tread.

The invention discloses a conductive agent combined type lithium ion battery positive pole piece, which comprises a current collector and a positive pole film adhered to the current collector. The positive pole film comprises a positive pole active material, a conductive agent and a binding agent, wherein the conductive agent is a combination of CB and CNTs or CB and GNPs or CNTs and GNPs or CB, CNTs and GNPs. A manufacture method comprises the steps of (1) adding the binding agent into solvent and evenly stirring and mixing; (2) adding the conductive agent combination of two or three of CB, CNTs and GNPs into the solvent and evenly stirring and mixing; (3) adding the positive pole active material and evenly stirring and mixing to obtain positive pole slurry; (4) coating the positive pole slurry on the current collector and obtaining the lithium ion battery positive pole piece after roasting and rolling. The positive pole piece is high in energy density, low in expansion rate, high in coulombic efficiency and high in compaction.

The invention discloses a concentrated feed for laying hens in egg-laying peak period. The feed comprises a laying hen dietary feed with main components of soybean meal, cottonseed meal, rapeseed meal, corn germ cake, corn germ meal, enzyme hydrolyzed feather meal, stone powder, calcium hydrogen phosphate, medical stone, salt, and methionine; a health care agent combination pack and a premix are added into the laying hen dietary feed; the health care agent combination pack comprises ovary protecting elements, microecological preparations, enzyme preparations, diluents, and Chinese herbal medicine health care agents; and the premix comprises coated vitamins, mineral elements, methionine, and carriers. The feed can prolong the egg-laying peak period of laying hens, improve the body immunity of laying hens, improve the quality of the eggs, allow the eggshell to have a good texture and a pure color, allow the yolk to have a dark color, and allow the eliminated hens to be full-fledged and have good quality.

A method of producing cementitious mixtures containing fly ash as one of the cementitious components, under air entrainment conditions. The method involves forming a mixture comprising water, cement, fly ash, optionally other cementitious materials, aggregate, conventional chemical admixtures, and an air entrainment agent and agitating the mixture to entrain air therein. Additionally, at least one sacrificial agent is also included in the mixture. The sacrificial agent is a material or mixture of materials that is not required to act as an air entrainment agent but interacts preferentially with components of the fly ash that otherwise neutralize, repress or depress the activity of the air entrainment agent. The invention includes cementitious mixtures and hardened concretes resulting from the method and fly ash treated with sacrificial agent, or air entrainment agent/sacrificial agent combinations, and processes for selecting suitable sacrificial agents.

The invention relates to a staining agent combination for tumor tissue cells, in particular to a staining agent combination for the tumor tissue cells. The combination comprises 0.01%-5% of a color developing agent, less than or equal to 6.5% of folic acid, 0.1%-10% of a leuco agent, less than or equal to 10% of a pH modifier and 3%-95% of water, wherein the color developing agent adopts methylene blue and/or dichlorophenolindophenol; the leuco agent adopts a reducing reagent; a targeted drug preparation adopts the folic acid; and the solution pH modifier and the water are adopted. The coloring agent for staining tumor cell can also be used for detecting the tumor cells. The invention also relates to a method of the staining agent combination used for detecting the tumor cells, a kit for detecting the tumor cells and a detection carrier.

A method for producing a confection such as chewing gum, as well as the confection so produced, incorporates a blend of physiological cooling agents, including menthyl glutarate and one or more of L-isopulegol and p-menthane-3,8-diol. In another embodiment the blend of physiological cooling agents is made in a modified release structure. The modified release/cooling agents combination is preferably obtained by physically modifying the properties of the combination of cooling agents by coating and drying. When incorporated into gum, these particles are adapted to enhance the shelf stability of the flavor and/or produce a modified release when the gum is chewed. In another embodiment, the blend of physiological cooling agent is included in a confection coating.

A method of producing cementitious mixtures containing fly ash as one of the cementitious components, under air entrainment conditions is described. The method involves forming a mixture comprising water, cement, fly ash, optionally other cementitious materials, aggregate, conventional chemical admixtures, and an air entrainment agent and agitating the mixture to entrain air therein. Additionally, at least one amine sacrificial agent is included in the mixture. The cementitious mixtures and hardened concretes resulting from the method and fly ash treated with sacrificial agent, or air entrainment agent/sacrificial agent combinations, are also described.

The invention provides a pesticide for killing piercing-sucking type insects. The pesticide comprises dinotefuran with the mass percentage of 1%-80%, and a pesticide-acceptable addition agent combination, or comprises an effective component A and an effective component B with the mass ratio in a range from 80:1 to 1:80, and a pesticide-acceptable addition agent combination, wherein the effective component A is dinotefuran, and the effective component B is one of indoxacarb, chlorfenapyr and pymetrozine. The invention further provides a method for preparing the pesticide into soluble liquid, wettable powder, a water dispersible granule product and a suspension agent product. According to the pesticide disclosed by the invention, the dinotefuran is mainly applied to internal suction and penetration of insects, the lasting period is long and the generation of drug resistance can be retarded; the pesticide has an excellent effect for preventing and treating insects; meanwhile, the pollution to the environment is alleviated and an insecticidal spectrum can be expanded. The pesticide disclosed by the invention has excellent effects on prevention and treatment of various piercing-sucking type insects including thrips, plant hoppers, leafhoppers, aleyrodid, aphids, scale insects, tea lesser leafhoppers and the like.

This invention discloses one positive light anti-erosion agent peeling agent combination, which comprises the following parts: a, occupying organic amine for weight of 10 to 50; b, monoethylene glycol monoalkyl ether for weigth of 0 to 70 percent; c, non photon electrode solvent for weight of 20 to 90; d, based on the said three component total weight for 0.01 to 10 non-ion surface active agent. This invention relates to positive light anti-erosion peel agent combination to etch process with excellent solve property and peeling property of pattern film for light resistance.