The invention provides a preparation method for 2,3,5,6-tetrafluorohydroquinone, comprises the reaction step of: hydrolyzing the heavy nitride of 2,3,5,6-tetrafluoro-4-aminophenol to obtain the target compound 2,3,5,6-tetrafluorohydroquinone. In the method, the total yield can reach at least 85 percent, and the product purity is high (higher than 98 percent). The invention is suitable for the industrial requirement. The reaction formula is shown in the specification.