326 results about "P-Aminophenol" patented technology

The invention relates to a phosphorus-containing fire retardant, a preparation method of the phosphorus-containing fire retardant and a flame-retardant epoxy resin prepared from the phosphorus-containing fire retardant, and especially relates to a phosphorus-containing nitrile / DOPO double-base structure phosphorus-containing fire retardant, a preparation method of the phosphorus-containing nitrile / DOPO double-base structure phosphorus-containing fire retardant, and flame-retardant epoxy resin prepared from the phosphorus-containing nitrile / DOPO double-base structure phosphorus-containing fire retardant. The flame-retardant epoxy resin solves the problem that the existing epoxy resin has low flame retardation efficiency and poor compatibility between a polymer matrix and a fire retardant. The preparation method comprises the following steps of 1, dissolving p-hydroxybenzaldehyde and tetrahydrofuran, adding triethylamine into the solution and carrying out stirring, 2, dissolving phosphonitrilic chloride trimer in tetrahydrofuran, dropwisely adding the solution into the reaction system, and carrying out heating and stirring, 3, cooling the reaction system, concentrating the filtrate, pouring the filtrate into water for precipitate separation, carrying out pumping filtration, carrying out recrystallization on the precipitates and carrying out drying to obtain intermediates, and 4, dissolving the intermediates by a solvent, adding p-aminophenol into the solution, carrying out heating reflux, adding DOPO into the reflux product, carrying out condensation, pouring the concentrate into cold ethanol for solid precipitation, and washing and drying the solids to obtain the phosphorus-containing nitrile / DOPO double-base structure phosphorus-containing fire retardant. The flame-retardant epoxy resin comprises epoxy resin, a curing agent and the phosphorus-containing nitrile / DOPO double-base structure phosphorus-containing fire retardant. The preparation method is used for preparing the phosphorus-containing nitrile / DOPO double-base structure phosphorus-containing fire retardant.

The invention relates to a catalyst for preparing p-aminophenol through catalytic hydrogenation of p-nitrophenol, and a preparation method thereof, and belongs to the technical field of catalysis. The carrier of the catalyst is a ceramic membrane, and the preparation method comprises the following steps of: modifying the membrane surface by using aminosilane; immersing in salt solution of an active ingredient; and performing hydrazine hydrate reduction to prepare a catalytic membrane. The invention has the advantages that: nano-scale catalyst particles are supported on the surface of the ceramic membrane modified by silane, and the activity and stability of the catalyst are improved; moreover, a problem that the catalyst is hardly separated from the product subsequently is avoided. The catalyst is simple in preparation process and high in activity and stability and can be widely applied to preparing the p-aminophenol through catalytic hydrogenation of the p-nitrophenol.

The invention concerns the reaction of benzene catalyst adding hydrogen, specific speaking, it's a kind of catalyst to produce 4-ammonia base-3-F benzene fen and its application. The catalyst is made of carrier, active parts and helping dose. The main active parts are: dear metal Pt, Pd or Rh, whose weight is of catalyst 0.1%--20%. Help doses are IA, ó�A, ó¾B, ó° or Sparse soil chemical element. The catalyst has the feature of high active in reactivation, good choosing ability and many reuses. The catalyst can also be used in other replacing nitric unit benzene adding hydrogen and catalyst process.

A quaternary ammonium salt ionic liquid of the present invention and its preparation and application methods belong to quaternary ammonium compounds, and its molecular composition is N, N, N-trimethyl-N-sulfobutyl-ammonium bisulfate, and its molecular formula is [HSO3-b -N(CH3)3]HSO4, the structural formula is as follows: the quaternary ammonium salt ionic liquid of the present invention is non-corrosive equipment and environment-friendly, and the quaternary ammonium salt ionic liquid catalyst of the present invention is used for nitrobenzene catalytic hydrogenation to synthesize p-amino The phenol reaction is a liquid phase method, the reaction temperature is 60-130° C., and the PAP yield reaches 19.5-88%.

The invention discloses a supported gold catalyst, a preparation method and an application thereof, and a p-aminophenol preparation method. The supported gold catalyst contains silica and nano-gold particles supported on the silica, the particle size of the supported gold catalyst is not greater than 0.6mm, the average aperture is 10-70nm, and the particle size of the nano-gold particles is 1-5nm. The supported gold catalyst has the advantages of simple preparation method, low cost, good catalysis performance, good repeatability, and good dispersion and small dimensions of the supported nano-gold particles.

The invention involves a load palladium amorphous alloy catalyst used for nitrophenol hydrogenation and preparation method and belongs to catalyst technology field. Said catalyst uses NaY, MCM-41, molecular screen, Al2O3, TiO2, SiO2 or MgO as carrier, and is loaded with Pd-B amorphous alloy, the quality of Pd is 0.1-0.5% of toatl quality of catalyst. The preparation process includes ultrasonic dispersion, vacuum impregnation, KBH4 chemical reduction under vacuum conditions, filtration and washing of carriers; it is characterized by introducing vacuum and ultrasonic radiation conditions. The advantages of the invention lies in its high activity of catalyst, low preparation cost and simple preparation process, it could widely apply to the preparation of p-aminophenol through nitrophenol catalysis and hydrogenation.

The invention provides a mesopore carbon load nickel hydrogenation catalyst and a preparation method thereof. For the load type catalyst, a carrier is mesopore carbon, an active component is metal nickel, and the mass of the nickel is 5-50 percent of that of the carrier. The preparation method comprises the following steps: soaking the mesopore carbon carrier in an organic soaking liquid containing nickel salt precursor under the action of ultrasonic, standing at room temperature, drying, and activating the precursor containing a metal component through the reducibility of the carrier, i.e. by a thermal reduction mode. The invention has the advantages of high dispersity of the active component, excellent performance of the catalyst, simple preparation process and low cost and can be used for preparing p-aminophenol by carrying out liquid-phase hydrogenation on p-nitrophenol.

The invention provides a sensitive detection method of alkaline phosphatase based on carbon-dots fluorescence ''quenching-recovery''. Carbon dots prepared by a simple hydrothermal method have low toxicity and good water solubility and fluorescent property. In the presence of potassium permanganate, fluorescence of carbon dots is quenched; and with a hydrolysate ascorbic acid or p-aminophenol of alkaline phosphatase (ALP), quenched fluorescence will be recovered again. By high catalytic activity of ALP, a novel fluorescence analysis method is established to realize highly sensitive detection of ALP. The method has advantages of novel principle, high sensitivity, good selectivity and simple and fast operation, and is adopted to avoid interference of false signals in a fluorescence quenching method and widen the application range of carbon dots-based biological detection.

The production process with p-nitrophenol material includes catalytic hydrogenation with Ni, Al or other metal catalyst with the reactant material being pumped to circulate between reactor and inorganic memobrane assembly; repeated filtering of circular material through inorganic membrane with the liquid phase product passing through the membrane pores; the conventional treatment of the collectedliquid phase product to obtain p-aminophenol crystal product; and the recovery and reuse of the solid catalyst in circular flow and finally in the reactor. During the process, fine suspended catalystis separated and recovered continuously.

The present invention provides a single step process for the preparation of p-aminophenol by contacting a mixture of nitrobenzene and water with hydrogen over a solid acid catalyst, terminating the reaction to obtain a reaction mixture containing the product, extracting the reaction mixture with an organic solvent, separating the aqueous layer containing the product, and then concentrating the aqueous layer by any conventional method to obtain the product.

N-(3,5-bis-disubstituted aminomethyl-4-hydroxy)benzyl aromatic sulfonamides and N-(3,5-bis-disubstituted aminomethyl-4-hydroxy)phenyl aromatic sulfonamides compounds in accordance with the animal test, are active in the prevention and the treatment of cardiac arrhythmia. These compounds are prepared as corresponding diamines by the condensation of optionally substituted aromatic sulfochlorides with p-hydroxybenzylamine, p-aminophenol, or the like, which followed by the Mannich reaction of the resulted corresponding aromatic sulfamides with formaldehyde and secondary amines; or directly obtained by the reaction of the aromatic sulfamides with 4-amino-2,6-bis-disubstituted aminomethylphenol. Subsequently, the diamines are reacted with various acids to provide their salts.

The invention discloses a conjugated microporous polymer, and a preparation method and application thereof. The preparation method of the conjugated microporous polymer comprises the following steps:under the atmosphere of argon or nitrogen, mixing a compound II, a compound III, cuprous iodide and a palladium catalyst into an diisopropylamine / organic solvent mixed solution, and uniformly carryingout stirring at room temperature; carrying out ultrasonic dispersion, carrying out freezing and deoxidizing, then carrying out heating to 50-120 DEG C, and carrying out a reaction for 24-72 hours; and carrying out cooling to room temperature, and carrying out filtering, washing and drying. An ion-loaded nano-composite catalytic material is prepared by taking the conjugated microporous polymer asa carrier to load nano-silver particles. The composite catalytic material can be used for efficient catalytic reduction of industrial pollutant p-nitrophenol, and the industrial pollutant p-nitrophenol is converted into common medicines and chemical raw material p-aminophenol. In addition, the catalyst has good solvent tolerance, stability and recyclability.

The invention relates to a novel method for preparing loading type nanometer nickel catalyst; the method takes a carrier loaded with a revulsant as a precursor to induce hydrazine hydrate to reduce a nickel salt solution; the crystal grains of the formed nanometer nickel is directionally deposited on the surface of the carrier with no aggregation; the loading type nanometer nickel catalyst prepared by the method has the advantages of high loading of activating components, small grain diameters, good dispersibility and high activity as well as being suitable for catalytic hydrogenation reaction.

The invention relates to a phthalaznone-containing poly(aryl ether nitrile) end-capped with maleimide and a preparation method thereof. Self-made 4-[4-(4-carboxyl phenoxyl) phenyl) -2-(4-carboxyl phenyl) naphthyridine-1-ketone or derivative thereof and 2, 6-dichlorobenzonitrile are used as polycondensation monomers. Meanwhile, other bisphenol and aromatic bi-halogen monomers can be added, p-aminophenol is used as an end-capping agent, and a solvent, a co-boiling dewatering agent and a catalyst are added for carrying out progressive polymerization reaction and synthesizing a phthalaznone-containing poly(aryl ether nitrile) resin end-capped with amino. On the basis, a phthalaznone-containing poly(aryl ether nitrile) polymer end-capped with amino, maleic anhydride, p-toluenesulfonic acid, a polymerization inhibitor, the solvent and the co-boiling dewatering agent are used as raw materials to prepare a phthalaznone-containing poly(aryl ether nitrile) resin end-capped with maleimide. The poly(aryl ether nitrile) resin can be co-cured with bis-maleimide or an epoxy resin, can be used in the fields of thermostable paint, coatings, adhesives, composite materials and the like and has broad application prospects.

The invention relates to a novel catalytic agent for preparing p-aminophenol by using nitrobenzene catalytic hydrogenation and a preparation method thereof. The catalytic agent enables active carbon to serve as a carrier, enables Pt to serve as a main catalytic agent and enables MoS2 to serve as an auxiliary catalytic agent. The preparation step of the catalytic agent comprises (1) preparing Pt / C catalytic agent, namely enabling the Pt to be loaded on the activated carbon through an infusion process; and (2) restoring the auxiliary catalytic agent MoS2 through steeping and roasting under certain H2, loading on the Pt / C, and finally obtaining the catalytic agent for preparing the p-aminophenol. The catalytic agent for synthesizing the p-aminophenol is high in productivity and high in selectivity, and the catalytic agent is good in stability. After 23 times of circulation, the catalytic agent keeps good activity, yield coefficient of the p-aminophenol is above 83%, and the catalytic agent has good industrial application prospect.

The invention discloses a phosphorus-nitrogen type flame retardant containing an active double bond as well as a preparation method and an application thereof. The preparation method comprises the following steps: carrying out Mannich reaction on 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide, p-aminophenol and paraformaldehyde in the presence of a solvent to obtain a product and washing the product with methanol to obtain a phenolic intermediate compound; reacting the phenolic intermediate compound with methacryloyl chloride in the presence of a solvent and an acid binding agent, filtering to remove acid binding agent salts generated in the reaction to obtain a crude product, purifying the crude product by virtue of washing, carrying out spin evaporation and drying to obtain the phosphorus-nitrogen type flame retardant containing the active double bond. The phosphorus-nitrogen type flame retardant containing the active double bond can be applied in preparation of flame-retardant polymer materials. The raw materials are easily available and the cost is low; the reaction conditions are mild and the yield is high; the purification and separation operations of the product are simple and the phosphorus-nitrogen type flame retardant is easily industrialized and complies with environmental requirements; the flame-retardant effect is good and the application range is wide.

The invention discloses a preparation method of a Ni-based catalyst modified by an aid Pt supported by multi-wall carbon nanotubes as a carrier and application. The preparation method comprises the following steps: firstly, performing acid modification on multi-wall carbon nanotubes by using nitro-sulfuric acid; by taking the multi-wall carbon nanotubes as a carrier, putting precursor salts of platinum and nickel according to the multi-wall carbon nanotubes to hexachloroplatinic acid hexahydrate and nickel nitrate hexahydrate according to a mass ratio of (5-10):(0.1-0.5):(5-10); further addingdeionized water, performing ultrasonic stirring, drying, and performing roasting and reduction, thereby finally obtaining an expected catalyst Pt-Ni / MWCNT. The catalyst prepared by using the method is low in cost, economic and effective, good in universality, good in environmental-friendliness, free of equipment corrosion and good in circulation property, and is relatively high in activity and relatively high in p-aminophenol selectivity under a relative gentle reaction condition in a process that p-aminophenol is prepared from nitrobenzene through one-step hydrogenation rearrangement, the production conditions can be improved, the production cost is reduced, and the product quality is improved.

The invention relates to a technique of synthesizing paraaminophenol by catalyzing and dydrogenating nitrobenzene, and belongs to the technical field of aminophenol. The invention is the technique of producing the paraaminophenol from the nitrobenzene catalyzing dydrogenating device in the metal salt liquors, wherein, the quality compounding rate of the material has a mass distribution ratio that Lewis acid metal salt: load metal Pt activator: nitrobenzene: hexadecyl trimethyl ammonium bromide: water is equal to 0.5 to 5 : 0.1 to 0.3 : 1 to 5 : 0.01 : 50. The invention has the reacting conditions that: a branch pressure of the hydrogen is 0.1 to 1.0 M Pa, a reacting temperature is 80 to 200 DEG C, and a reacting time is 1 to 10 hours. The reaction which is proceed in the neutral or acidulous metal salt liquors has not high requirements to the device material, thereby preventing using abundant ammonia during the managing process, simplifying the production craftworks and overcoming the problems of the canker of the device and the serious environmental pollution; the metal salt and the activators can be separated from the reaction system for being reused repeatedly; therefore, the invention reduces the production cost, also prevents the discharging of the waste liquids and makes the yield of PAP highly reach to 25 to 73 percents.

The invention relates to a catalyst used for synthesis of p-aminophenol by catalytic hydrogenation of nitrobenzene, a preparation method and an application method, belonging to catalyst containing both platinum and organic compound field. The catalyst is a supported and bi-functional catalyst, and comprises room temperature ionic liquid of N, N, N-trimethyl-N-sulfobutyl-ammonium bisulfate which is one component of the active components, active metal Pt which is the other component of the active components, and silica gel carrier; wherein, the loading of the room temperature ionic liquid of N, N, N-trimethyl-N-sulfobutyl-ammonium bisulfate is 5 to 50%, while the loading of the active metal Pt is 0.01 to 1.5%. The invention has the advantages that: as a highly active heterogeneous catalyst, the catalyst overcomes the shortcomings that the homogeneous catalyst in prior art can not be used repeatedly, the reaction conditions of the heterogeneous catalyst in prior art are severe and the activity is low, and the problems that the equipment is liable to corrosion and the discharge of wastewater pollutes environment are solved.

The invention belongs to the technical field of catalysts, and in particular relates to a catalyst for synthesizing p-aminophenol by hydrogenation reduction of nitrobenzene and a preparation method thereof. The catalyst takes an all-silica mesoporous molecular sieve as a carrier and is prepared by loading active components, namely Pt and Ni, on the carrier. The preparation method for the catalyst comprises the following steps: impregnating the carrier by adopting a wet method, namely dripping solution of metal salts of the active components onto the carrier, baking the carrier in air and reducing the carrier with hydrogen to obtain the catalyst. The catalyst is used for catalytic hydrogenation of the nitrobenzene; and the intermediate product is rearranged in acidic aqueous solution to prepare the p-aminophenol, wherein the yield of the target product can reach over 75 percent. The preparation method for the catalyst is simple; and because the catalyst has relatively good stability and can be circulated for over 16 times, the catalyst has good industrial application prospect.

The invention discloses a method for preparing high-efficiency concrete water reducer of aromatic amino sulfonic acid through condensation reaction of waste water from synthesis process of p-aminophenol with sulfanilic acid and formaldehyde. The molar ratio of the materials of phenolic compound, sulfanilic acid and formaldehyde for condensation reaction during the preparation process is controlled to be 1:(0.5-1):(1.5-2.5); the molar ratio of phenol added to the sulfanilic acid is controlled to be (0-1):1; the reaction temperature and the pH value of the reaction solution are controlled on a segmental basis; and after the reaction is finished, the reaction solution is condensed under vacuum condition to obtain the high-efficiency water reducer liquid of aromatic amino sulfonate with the mass ratio of 40%. Not only is the environment pollution problem in the production process of p-aminophenol solved, but also the high-efficiency concrete water reducer of aromatic amino sulfonic acid with low cost can be prepared.

A preparation method of a fiber composite membrane catalyst is as follows: firstly, cellulose fiber is subjected to carboxymethylation treatment, a large amount of carboxyl groups are introduced, metal organic framework MOFs are synthesized in situ on the fiber by immersion stirring, nano-Ag (Ag NPs) is loaded and dispersed on the MOFs by microwave reduction, and a nano-paper-based composite filmcatalytic material is finally obtained by washing, suction filtration, and paper making and forming; the practical size of the Ag nano-particles is between 6 and 20 nm, and rapid catalytic degradationand conversion of p-nitrophenol in wastewater to p-aminophenol can be realized by synergistic effects of the MOFs and the Ag nano-particles. The primary conversion rate is over 99%. Compared with a traditional granular catalyst, and the problems of difficult recovery, short catalytic time and high efficiency can be solved. The fiber composite membrane catalyst can be used as a filler to prepare acatalytic membrane material by mixing for paper making with other plant fibers. The catalytic membrane material has broad application prospects in the field of treating industrial wastewater.

The invention discloses a preparation method of a Pt-C (platinum-carbon) catalyst for nitrobenzene hydrogenation, which is applied to a high-activity Pt-C catalyst for nitrobenzene hydrogenation reduction to generate p-aminophenol. In order to avoid the problems of chloride oil poison and the like in the preparation of a catalyst by taking chloroplatinic acid as a precursor, ethanolamine hydroxyl platinum is used as a precursor; meanwhile, sodium dodecyl benzene sulfonate is used as a protective agent to control the particle size of the Pt particles and is prepared through two-step reduction by H2 and NaBH4. The dispersity of the active component Pt particles is good, the mass percentage is 2-5%, and the particle size of the particles is less than or equal to 5nm. The catalyst prepared by the method shows perfect catalytic activity and reaction selectivity in a reaction of generating p-aminophenol through nitrobenzene hydrogenation, wherein the conversion rate is 99.09%, and the selectivity reaches 92%.

The invention relates to a micron acicular-structure N-methyl-2-phenyl-3,4-fullerenylpyrrolidine, and a preparation method and application thereof. The fullerene C60, benzaldehyde and sarcosine are used as raw materials to prepare the N-methyl-2-phenyl-3,4-fullerenylpyrrolidine and N-methyl-2-phenyl-3,4-fullerenylpyrrolidine in a micron acicular structure; and the micron acicular-structure N-methyl-2-phenyl-3,4-fullerenylpyrrolidine is used as a support to prepare the catalyst for preparing p-aminophenol from nitrobenzene by catalytic hydrogenation. The product prepared by the technique has the advantages of high yield and high purity; and the prepared catalyst has the advantages of high activity and long service life.

The invention discloses a method for industrial production of a sorafenib tosylate polymorphic substance I. The method comprises the following steps: by adopting N-methyl-4-chloro-pyridine carboxamide and p-aminophenol as raw materials, adding a proper amount of alkali to obtain an intermediate 4-(4-aminophenoxy)-N-methyl-2-pyridine carboxamide by virtue of nucleophilic substitution reaction in an organic solvent, performing condensation on 4-(4-aminophenoxy)-N-methyl-2-pyridine carboxamide and 4-chloro-3-benzenyl trifluoride isocyanate to obtain free alkali of sorafenib, finally performing back-flow and salification with p-toluenesulfonic acid in a mixed solvent of acetone and acetonitrile, and cooling and crystallizing to obtain sorafenib tosylate of the polymorphic substance I. Compared with the prior art, the scheme of the method disclosed by the invention is simple and safe to operate, is mild in reaction condition, and does not need crystal form transformation steps; an obtained product is single and stable in crystal form and high in purity, and is suitable for large-scale industrial production.

The invention provides an in-situ nitrogen-doped hollow carbon ball and a preparation method thereof and a preparation method and application of an electrode material and relates to the technical field of electrochemistry energy materials. According to the in-situ nitrogen-doped hollow carbon ball, the SiO2 ball is used as a rigid membrane plate, formaldehyde is used as a carbon source, and one ormore of p-acetamidophenol, 2-acetamidophenol, p-aminophenol and m-aminophenol are used as a nitrogen source; the rigid membrane plate, the carbon source and the nitrogen source are placed in a reaction system of ethyl alcohol, water and ammonium hydroxide; through a sol-gel process, the SiO2 ball is wrapped by phenolic resin prepared through an aldol condensation reaction, the SiO2 / phenolic resinball with a core-shell structure is prepared, and the nitrogen-doped hollow carbon ball is obtained through carbonization and silicon removal. The prepared nitrogen-doped hollow carbon ball has the advantages of being small in nanoscale, even in shape, high in specific surface area and the like and has wide application prospects in the aspects such as energy storage, catalysis and adsorption.

The invention generally relates to biological engineering of microorganisms and production of chemical compounds therefrom. More particularly, the invention relates to novel genetically engineered microorganisms for the fermentative production of p-aminobenzoic acid and related compounds from fermentable carbon substrates. The biologically derived PABA and related compounds from fermentable carbon substrates can be used in a number of applications including as a food supplement or raw materials for the syntheses of other industrial chemicals or polymers.

The invention provides a molybdenum disulfide / carbon composite material and a preparation method and application thereof. The preparation method comprises the following steps: taking water as a solvent at first; adding p-aminophenol, formaldehyde and ammonia water to prepare multilayered C hollow balls; regulating the amount of the water, 3-AP, the formaldehyde and the ammonia water to regulate and control the number of the layers of the C hollow balls; taking the synthesized C hollow balls as a framework, taking ammonium molybdate as a molybdenum source, taking thiourea as a sulfur source, and using a hydrothermal method to obtain a MoS2 / C composite material. The preparation method is simple, safe in preparation process, low in energy consumption and high in operability.

A carried catalyst for synthesizing p-aminophenol is composed of the carrier (SiO2) and the active component chosen from Pt, Pt-Ru, Pt-Co, Pt-Ba, Pt-Mg, Pt-Ca, Pt-Al, Pt-B and Pt-Mo. Its preparing process and application method are also disclosed.

The invention discloses a high-sensitivity phenol electrochemical sensor and a preparation method thereof. The preparation method comprises the following steps: subjecting a prepared multi-walled carbon nanotube-bridged 3D graphene conductive network to ultrasonic dispersion in water, dispensing an obtained solution on a polished glassy carbon electrode and carrying out drying so as to obtain the sensor. The nanometer sensor prepared from a 3D functionalized nano-material can realize electrochemical detection of p-aminophenol, p-chlorophenol, p-nitrophenol and the like in a complex environment containing other interference substances, and effectively overcomes the defect that CDs are easy to shed; non-covalent bridging of carboxylated carbon nanotubes substantially improves conductivity of the system and selectivity of CDs; and the method is higher in economic performance, better in feasibility and higher in sensitivity.