154 results about "Dinitrophenol" patented technology

An invention relating to therapeutic pharmacological agents and methods to chemically induce intracellular hyperthermia and / or free radicals for the diagnosis and treatment of infections, malignancy and other medical conditions. The invention relates to a process and composition for the diagnosis or killing of cancer cells and inactivation of susceptible bacterial, parasitic, fungal, and viral pathogens by chemically generating heat, and / or free radicals and / or hyperthermia-inducible immunogenic determinants by using mitochondrial uncoupling agents, especially 2,4 dinitrophenol and, their conjugates, either alone or in combination with other drugs, hormones, cytokines and radiation.

A process for treating the waste water in oil field by electricity-multi-phase catalytic reaction features that under the existance of external electric field, the organic pollutants in the said waste water are catalytically oxidized by the surface of catalyst. The catalyst is composed of the active components chosen from one or several oxides of Fe, Co, NI, Mn, Cu, Ti, W and Pb and the carrier chosen from SiO2, Al2O3, zeolite molecular sieve and activated carbon. Among the mentioned catalyst, one or several oxides of rare earth metals as auxiliaries may be added. The said catalyst is made upthrough impregnating, oven-drying and sintering; and it can effectively treat oil-contained waste water as well as dinitrophenol waste water, fertilizer plant waste water, cutting liquid waste water,etc.. Its advantages are high effect and low cost.

An invention relating to therapeutic pharmacological agents and methods to chemically induce intracellular hyperthermia and / or free radicals for the diagnosis and treatment of infections, malignancy and other medical conditions. The invention relates to a process and composition for the diagnosis or killing of cancer cells and inactivation of susceptible bacterial, parasitic, fungal, and viral pathogens by chemically generating heat, and / or free radicals and / or hyperthermia-inducible immunogenic determinants by using mitochondrial uncoupling agents, especially 2,4 dinitrophenol and, their conjugates, either alone or in combination with other drugs, hormones, cytokines and radiation.

A Se-enriched plant growth regulator is an aqueous product prepared from the sodium (potassium or ammonium) selenate (or selenite) and the sodium (potassium or ammonium) salt of 5-nitroguaiacol, 2,4-dinitrophenol, or catechol. Its advantages are high chemical and physical stability, and high effect on increasing the content of organoselenium in grains of crops and promoting photosynthesis.

The invention provides a method for treating hydrolyzed waste water and recovering resource in a disperse blue production process, which comprises the following steps that: A) the pH value of the hydrolyzed waste water in the disperse blue production process is adjusted to between 2 and 3, the waste water is filtered, and filter cakes are dried to obtain a crude product 2,4-dinitrophenol of which the purity reaches more than 93.5 percent; B) filter liquor passes through an adsorption tower filled with styrene macroporous absorbent resin under the conditions that the temperature is between 10 and 50 DEG C and the flow rate is between 0.5 and 4.0 BV / h (BV is resin bed volume); C) 4 to 8 mass percent sodium hydroxide and water are taken as desorption agents to desorb and regenerate the macroporous absorbent resin adsorbed with the 2,4-dinitrophenol, the desorption temperature is between 40 and 90 DEG C, and the flow rate of the desorption agent is between 0.5 and 2.0 BV / h; and D) the pH of a desorbed eluent is adjusted to between 2 and 3 by 98 percent sulfuric acid, the eluent is filtered and dried, the crude product 2,4-dinitrophenol is recovered, the purity of the crude product 2,4-dinitrophenol reaches more than 93 percent, and the filter liquor of the eluent in the batch and eluent obtained in step C) in the next batch undergo cyclic operation of step D) together.

The invention relates to a fertilizer effect enhancing additive. The additive mainly comprises 2, 4-dinitrophenol, alpha-naphthyl acetic acid, methoxy-5-nitrophenol, 2-nitrophenol, p-nitrophenol, dodecylbenzene sulfonic acid, polyaspartic acid, triiodobenzoic acid, biological azotobacters, protein peptides and polyether ternary alcohol. According to the additive provided by the invention, the effect of fertilizer is enhanced effectively and the utilization rate of the fertilizer is improved, so that the purposes of increasing the yield and lowering the fertilizer consumption are realized. Theadditive also has the advantages that the environmental pollution is reduced, and the yield and the quality of crops, flowers, mushrooms and vegetables are improved.

The invention relates to a catalyst used for coupling reaction of carbon dioxide and an epoxy compound. The catalyst is a Salen-metal complex (I) which has a structural formula shown in the specifications, wherein R1 is 1,2-disubstituted diamine; when R2 is a substituent group with a formula shown in the specifications or nitrogen substituted heterocyclic compound, R3 is tertiary butyl, hydrogen, alkyl or alkoxy; or when R2 is the tertiary butyl, hydrogen, alkyl or alkoxy, R3 is the substituent group with the formula shown in the specifications or nitrogen substituted heterocyclic compound; M is chlorine or bromine, Z is nitrogen or phosphorus, and Y1, Y2 and Y3 are alkane with 1 to 16 carbon atoms respectively; and X is nitrate, boron tetrafluoride, trichloroacetic acid, azide or 2,4-dinitrophenol. For the Salen-metal complex, preparation steps are simple and convenient to operate, cost is low and heavy metal pollution is avoided; 1 mol of catalyst catalyzes 3750mol of cyclic carbonate ester; a cocatalyst and a solvent are not needed; and the cyclic carbonate ester content of a product is over 99 percent.

A disclosed fertilizer quick-acting long-acting synergist comprises the following raw materials: 2, 4-dinitrophenol sodium salt, 4-nitrophenol sodium salt, 2-nitrophenol sodium salt, polyaspartic acid, polyglutamic acid, hydroquinone, thiourea, 3,4-dimethyl-1H-pyrazolium dihydrogen phosphate, acrylamide, dicyandiamide, N-J N-(N-butyl)thiophosphoric triamide, 2-methoxy-5-nitrophenol, sodium alpha-naphthyl acetate, 6-benzylaminopurine, humic acid and potassium hydroxide. The fertilizer quick-acting long-acting synergist is substantially improved in selection and proportion of the raw materials; by cooperating with a fertilizer, the synergist is capable of making the fertilizer rapidly work, keeping long-term effectiveness of the fertilizer, prolonging the fertilizer effectiveness up to 140 days mostly, comprehensively improving fertilizer effective availability by 30% or more and saving fertilizer usage amount by 20%, wherein crops applied with the synergist have substantial effect on absorption and growth just after 1-2 days.

The invention discloses a bacterial bio-fertilizer synergist and a production method thereof. The synergist has the following components: 10-20% of bacillus subtilis, 15-30% of polyaspartic acid, 5-10% of alpha-naphthyl acetic acid (sodium), 10-20% of 2, 4-dinitrophenol (sodium), 5-10% of sodium para-nitrophenolate and 5-10% of 6-benzylaminopurine. The production method is as follows: the 10-20% of bacillus subtilis, the 15-30% of polyaspartic acid, the 5-10% of alpha-naphthylacetic acid (sodium), the 10-20% of 2, 4-dinitrophenol (sodium), the 5-10% of sodium para-nitrophenolate and the 5-10% of 6-benzylaminopurine are added to a stirrer for thoroughly and evenly mixing, bagged in a plastic bag and sealed, thus the product is obtained. When in use, the bag of the biological bacteria fertilizer synergist is unpacked; the synergist is mixed with the applied chemical fertilizer according to the amount of 10-20g per mu, and then applied according to the application method of the chemical fertilizer.

The invention pertains to the technical field of bio-treatment of environmental pollutants, particularly relates to a bacterium for degrading o-nitrobenzaldehyde and the applications thereof in bio-treatment of waste water and remediation of soil environmental pollution. The degrading bacterium of o-nitrobenzaldehyde is the strain ND1 of Alcaligenes sp. The bacterium can degrade o-nitrobenzaldehyde with high efficiency under aerobic condition, and utilize albocarbon, p-nitrophenol, o-nitrophenol, ortho-aminophenol, toluene, p-dimethylaminobenzaldehyde, 2, 4-dinitrophenol, para hydroxy benzoic acid, diphenylamine, benzoic acid, xylene and a plurality of other aromatic compounds. The Alcaligenes sp.ND1 is sensitive to five common antibiotics of tetracycline, kanamycin, streptomycin, chloromycetin and ampicillin, thus providing safe guarantees in the application thereof in the bio-treatment of waste water and remediation of soil environmental pollution.

The invention discloses a synthetic process for 2,4-dinitroanisole. The synthetic process comprises the following steps of: heating and dissolving composite inorganic base into methanol to obtain a methanol alkali solution, then dropwise adding the methanol alkali solution into a methanol solution containing the 2,4-dinitroanisole to react, after finishing the reaction, carrying out cooling crystallization on the obtained reaction liquid, filtering to obtain a filter cake and filter liquid, washing the filter cake by utilizing water of 30-35 DEG C to obtain solids and washing liquid, and drying the obtained solids to obtain 2,4-dinitroanisole; and regulating the pH of the obtained washing liquid to be 2-4, and carrying out the cooling crystallization, filtering, water washing and drying to obtain 2,4-dinitrophenol. The synthetic process has the advantages that the purity and yield of the 2,4-dinitroanisole are improved, the water volume of mother liquid is effectively reduced, and the mother liquid can be continuously and mechanically applied after being processed, is accordant with industrial production requirements and can be used for industrial production.

The invention discloses a preparation method of 2-amino-4-nitrophenol. The method consists of the steps of: (1) in a solvent and in the presence of alkali, subjecting 2, 4-dinitrochlorobenzene to hydrolysis reaction, and then carrying out acidification reaction with acid to obtain 2, 4-dinitrophenol; and (2) in the presence of a catalyst, subjecting the 2, 4-dinitrophenol obtained in step (1) and hydrazine hydrate to reduction reaction so as to obtain the 2-amino-4-nitrophenol, with the catalyst being a combination of ferric trichloride hexahydrate and activated carbon. The preparation method of the invention has the advantages of milder reaction conditions, no byproduct, economical efficiency and environmental protection, simple post-treatment, and high reaction yield, and is suitable for industrial production. (reaction formulas).

The invention relates to a method for preparing a quick-acting synergist for a fertilizer. The method comprises the following steps of: smashing and sieving 0.1 to 35 percent of sodium 2,4-dinitrophenolate, 0.1 to 20 percent of alpha-nafusaku, 0.1 to 20 percent of indole potassium butyrate, 1 to 15 percent of polyglutamic acid, 0 to 5 percent of 6-benzyladenine, 0.1 to 5 percent of 2-methoxy-5-nitrophenol in proportion to obtain powder or granules of 20 to 60 meshes; uniformly mixing the components in different types; adding 0.1 to 5 percent of potassium hydroxide or sodium hydroxide which is easy to dissolve in water; and totally mixing the components once again to obtain a finished product. The quick-acting synergist for the fertilizer fulfills the aims of remarkably promoting growing effects of crops within 1 to 2 days, saving the using amount of the fertilizer by 20 to 25 percent, improving the utilization ratio of the fertilizer by 30 to 35 percent, increasing the yield of the crops by 20 to 25 percent and increasing both production and income of the crops, and brings positive and considerable economic and social benefits.

The invention discloses a cadmium coordination polymer and an application thereof to the detection of nitro compounds in water. The cadmium coordination polymer is prepared in a simple condition. The cadmium coordination polymer has a stable structure in water and has very good selectivity and relatively low detection limit on 2,4-dinitrophenol; the fluorescence quenching efficiency of 70 ppm of 2,4-dinitrophenol to the cadmium coordination polymer dispersed in the water can reach 97%. Moreover, the cadmium coordination polymer can be separated and recycled for multiple times, therefore relatively high quenching efficiency is kept.

A Safe and effective treatment methods to cure and curtail tuberculosis affliction described using high dose Vitamin C, and other known anti-mycobacterium tuberculosis drugs especially rifampicin administered intravenously for 6 weeks instead of 6 to 24 months of conventional treatment. Insulin is administered to induce moderate hypoglycemia to augment and add effectiveness of anti-tuberculosis drugs and Vitamin C. Invention also delivers the drugs directly to a tuberculin lesion through a catheter. An embodiment of the invention uses a nebulizer and other methods of administration of Vitamin C with anti-tuberculosis drugs, interferon Y−, Coley's vaccine, dinitrophenol hyperthermia, ozone therapy, Hydrogen peroxide therapy and artemisinin, combined with oxygen supplementation including autohemotherapy with ozone, hyperbaric therapy, and hypertheramia to increase the respiration of the M. tuberculosis bacteria which has a killing effect.

The invention relates to a method for preparing 2-amino-4-nitrophenol, in particular to a method for preparing 2-amino-4-nitrophenol through liquid catalytic hydrogenation. 2,4-dinitrochlorobenzene is hydrolyzed to obtain industrial 2,4-dinitrochlorobenzene serving as a raw material, and 5 percent of Pd / C is used as a catalyst, so that the 2-amino-4-nitrophenol is prepared by performing catalytic hydrogenation on a liquid phase system. Compared with original sodium sulfide reduction, the liquid catalytic hydrogenation process disclosed by the invention has the advantages of low pollution, high yield and high quality; meanwhile, the catalytic hydrogenation system takes water serving as a solvent to replace an alcohol solvent which is low in boiling point and easy to volatilize, so that the problem of solvent recycling in the catalytic hydrogenation process is solved, and the safety of production is improved.

The invention discloses a method for producing 2, 4- dinitrobenzene methyl ether and 2, 4-dinitrophenol simultaneously, which is characterized by comprising the following steps: feeding and reacting stage: adding methanol and 2, 4- dinitro chloro benzene into a reaction device, heating until the 2, 4- dinitro chloro benzene is complately dissolved, and dripping sodium hydroxide water solution for reaction, so as to obtain the mixture of 2, 4- dinitrobenzene methyl ether and 2, 4- dinitrophenol; extracting 2, 4- dinitrobenzene methyl ether; obtaining methanol through steaming after reaction, adding water, regulating pH, lowering the temperature and suction filtering, washing a filter cake through water, and then drying, so as to obtain 2, 4- dinitrobenzene methyl ether; and extracting 2, 4- dinitrophenol; regulating the pH value of obtained filter liquor, cooling and crystallizing, washing through water, filtering, and drying so as to obtain 2, 4- dinitrophenol. The process is simple, the reaction time is short, the efficiency is high, the use level of the methanol can be effectively reduced, and the toxicity is lowered.

The invention discloses a naphthyl methyl imidazole modified silica gel adsorbent and a preparation method and application of the naphthyl methyl imidazole modified silica gel adsorbent. The technical scheme provided by the invention is characterized in that the naphthyl methyl imidazole modified silica gel adsorbent has the following structure as shown in the specification. The invention also discloses the preparation method of the naphthyl methyl imidazole modified silica gel adsorbent and the application of the naphthyl methyl imidazole modified silica gel adsorbent in a separation enrichment solution-2, 4-dinitrophenol. The naphthyl methyl imidazole modified silica gel adsorbent is simple in preparation process, novel in structure, high in multiple of enrichment on 2, 4-dinitrophenol in the solution, easy to elute, high in adsorption efficiency and adsorption quantity, and invariable in recovery rate after being used for multiple times.

The invention is a method of processing the waste water containing nitrobenzene, 2, 4- dinitrophenol and para-nitrochlorobenzene, pumping the basic waste water in a water distributing tank or the neutral water produced by using 98% sulphuric acid to regulate the pH value up to 7-8, into an electro-catalyzing device with activated carbon particle group, the voltage and current of the device, staying for a short time and then making the outgoing water pass through a medium tank for buffering, adding in 98% sulphuric acid to regulate the pH value up to primary effluent standard in the list 4 of 'Sewage Synthetic Effluent Standard' of the national GB8978-1996 and discharging. It has characters of effective degrading the industrial waste water containing nondegradable basic or neutral organic pollutants like nitrobenzene, 2, 4- dinitrophenol, para-nitrochlorobenzene, etc.

The invention discloses a preparation method for 2-amino-4-nitrophenol. The preparation method for the 2-amino-4-nitrophenol, provided by the invention, comprises the following step: subjecting 2,4-dinitrophenol and hydrazine hydrate to a reduction reaction in the presence of a catalyst, thereby preparing the 2-amino-4-nitrophenol, wherein the catalyst is a combination of ferric chloride hexahydrate (FeCl3.6H2O) and activated charcoal. The preparation method disclosed by the invention has the advantages of milder reaction conditions, no byproduct, economical efficiency, environment-friendliness, simple aftertreatment and high reaction yield, thereby being adaptable to industrial production.

The invention discloses a 2,4-dinitrophenol surface molecular imprinting polymer and a preparing method and application thereof. According to the key point of the technical scheme, activated silica is used as a carrier, absolute ethyl alcohol is used as solvent, 2,4-dinitrophenol is used as template molecule, 3-aminopropyl triethoxy silane is used as a functional monomer, tetraethoxysilane is used as a cross-linking agent, glacial acetic acid is used as an initiator, the substances are vibrated in a water bath at the temperature of 30 DEG C to trigger polymerization for 9-30 h, template molecules are eluted, or Soxhlet extraction is carried out on the template molecules, and the target product 2,4-dinitrophenol surface molecular imprinting polymer is obtained through methyl alcohol washing and vacuum drying at the temperature of 60 DEG C. The prepared 2,4-dinitrophenol surface molecular imprinting polymer is uniform in particle size, good in mechanical performance, high in selective adsorbability, large in adsorption capacity, easy to regenerate and recycle and capable of being used in high-selectivity separation and enrichment pretreatment of 2,4-dinitrophenol and 2,4,6-trinitrophenol.

The invention relates to a liquid chemical fertilizer synergism additive. 0-20 percent of 2,4- dinitrophenol, 0-20 percent of a-naphthylacetic acid, 0-20 percent of indoleacetic acid, 0-20 percent of indolebutyric acid, 0-30 percent of o-nitrophenol, 0-30 percent of p-nitrophenol, 0-20 percent of 5- nitro guaiacol, 0-20 percent of guaiacol, 0-10 percent of brilliant blue, 0-10 percent of polyoxyethylene ethers surfactant and 0-70 percent of methanol according to the weight content are mixed and stirred to produce the liquid chemical fertilizer synergism additive. The fertilizer synergism additive overcomes the shortages of the existing chemical fertilizers, improves chemical fertilizer utilization ratio, reduces chemical fertilizer application and pollution to the environment, has obvious synergism effect, reaches the purpose of increasing production and efficiency, environmental protective and reducing cost, therefore, the popularization of the liquid chemical fertilizer synergism additive has significant social meaning in China as a big agricultural Country.

The present invention is one kind of chemical fertilizer synergizing additive, which is brilliant yellow mixture powder of 2, 4-dinitrophenol (sodium) 0.1-60 wt%, alpha-naphthylacetic acid or sodium alpha-naphthylacetate 0.1 -40 wt%, indolacetic acid or sodium indolacetate 0.1-30 wt%, and dodecyl benzene sulfonic acid or sodium dodecyl benzene sulfonate 0.1-10 wt%. It is added into composite fertilizer in the amount of 0.01-10 wt%, and the mixture is pelletized. It can raise the utilization rate of chemical fertilizer, reduce use amount of chemical fertilizer, reach obvious yield increasing effect, reduce environmental pollution and lower agricultural production cost.

The invention discloses a method for recovering 2,4-dinitrophenol hydrogenation reduction byproduct to prepare 2-amino-4-acetamidoanisole. The method comprises the following steps: separating a 2-amino-4-nitrophenol and 2-nitro-4-aminophenol mixture to obtain a 2-nitro-4-aminophenol single component; mixing the 2-nitro-4-aminophenol with an alkylation reagent, and carrying out a phenolic hydroxyl group alkylation reaction and an amino group acylation reaction to obtain 2-nitro-4-acetamidoanisole; and carrying out nitro group reduction on the 2-nitro-4-acetamidoanisole to obtain the 2-amino-4-acetamidoanisole. The method provides a brand new method for the synthesis of the fine chemical engineering intermediate 2-amino-4-acetamidoanisole with important uses, reduces the content of organic matters in 2-amino-4-nitrophenol production wastewater, reduces the treatment difficulty of enterprises' industrial wastewater, converts wastewater components into the fine chemical engineering intermediate with important production uses, and increases the enterprises' economy income.

The invention relates to the technical field of processing and producing of composites, in particular to a protection coating for a book edge sealing adhesive packaging box.The protection coating is characterized by being prepared from, by weight, 5 parts of ethyl alcohol, 6 parts of modified epoxide resin, 1 part of lignosulfonic acid, 2 parts of glycerol triacetate, 3 parts of sodium tripolyphosphate, 1 part of nanoscale ceramic powder, 4 parts of silane coupling agent KH-520, 1 part of iso-tridecanol polyoxyethylene ether, 1 part of 2,4-dinitrophenol, 6 parts of mica powder, 1 part of chitosan, 4 parts of anti-aging agent, 1 part of pentaerythritol, 1 part of lauric acid and 5 parts of additive.The method is reasonable, operation is convenient, and matching is reasonable.

The invention relates to an analysis method of testing the nitrate reductase activity in the soil, which includes the following steps: 1) n dried and screened soil samples are weighed, adopted and put into test tubes; 2, 4-dinitrophenol solution is added into the test tubes and mixed to be even; and then substrate potassium nitrate solution is added into n-1 test tubes and the same amount of distilled water is added into the other one test tube for sample comparison; glucose solution is respectively added into the test tubes, which is then supplemented by distilled water to be 5 to 10ml and cultivated under constant temperature; 2) the distilled water is added to supplement to 50 to 100ml; 3) potash alum saturated solution is added in to be oscillated and filtered; 4)the distilled water and a chromogenic reagent are added into the filtrate, and a light absorption value A is determined under 520nm; 5) the content of nitrite in the samples is calculated. The analysis method has the advantages of: 1) simplification of operation steps and reduction of the complicacy and uncertainty during the anaerobic culturing process; 2) reduction to dependency on the equipment requirements; 3) high accuracy and easiness in operation; 4) stable and reliably result, and good repeatability.

The present invention discloses a determination method for 2,4-dinitrophenol in dry food packaging paper. The determination method comprises: standard working solution preparation, sample solution preparation, high-performance liquid chromatography analysis, standard curve drawing and result calculation. According to the determination method, extraction is performed on dry food packaging paper to obtain 2,4-dinitrophenol, a DAD detector is adopted to carry out qualitative confirmation and quantitative detection on the 2,4-dinitrophenol, operation is simple and accurate, the target object and other impurity chromatographic peaks brought by the sample matrix can be well separated with the used chromatographic conditions, good linear correlation is provided, a detection limit is 0.44 mg / kg, an average relative standard deviation is 1.6%, a standard addition recovery rate is 93.20-116.62%, and characteristics of rapidness, accuracy, high sensitivity, good repeatability, high recovery rate and the like are provided. The determination method is especially suitable for determination of 2,4-dinitrophenol content in dry food packaging paper.

The invention relates to the technical filed of biological degradation of pesticide residue, in particular to an analysis method for fast detecting the degradation rate of organophosphorus degrading bacteria. The method comprises the following steps: inoculating organophosphorus degrading bacterial strains into an organophosphorus-inorganic salt culture medium according to the inoculating amount with the volume ratio of 5 percent to 10 percent for fermentation culture; carrying out centrifugation after the fermentation to obtain supernate which is a sample solution to be detected; adding 0.2 to 0.4 mL indicating agents of dinitrophenol into every 10 mL sample solution to be detected; then, adopting water for defining the volume to 50 mL; then, adding 10 percent sodium carbonate solution or 5 percent sulfuric acid solution into the solution; next, adding 5 mL molybdenum-stibium color developing resistant agents to be uniformly shaken after the solution become light yellow; adding water for defining the volume; placing the solution for 20 to 30 min for color development under the condition of room temperature; carrying out colorimetric determination at 700 nm after the color development; and checking and obtaining the corresponding phosphor content from a calibration curve. The ratio of the obtained phosphor content to the total phosphor concentration in organophosphorus farm insecticide is the degradation rate of the organophosphorus degrading bacteria. The analysis method of the invention can be used for direct analysis of biochemical samples without any pretreatment.

A composition and method of treatment of neuromuscular, neuromuscular degenerative, neurodegenerative, autoimmune, developmental, traumatic, hearing loss related, and / or metabolic diseases, including spinal muscular atrophy (SMA) syndrome (SMA1, SMA2, SMA3, and SMA4, also called Type I, II, III and IV), traumatic brain injury (TBI), concussion, keratoconjunctivitis sicca (Dry Eye Disease), glaucoma, Sjogren's syndrome, rheumatoid arthritis, post-LASIK surgery, anti-depressants use, Wolfram Syndrome, and Wolcott-Rallison syndrome. The composition is selected from the group consisting of 2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP, bipartite 2,3-dinitrophenol, 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, or 3,5-dinitrophenol (2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP) prodrugs; Gemini prodrugs, bioprecursor molecules, and combinations thereof. A dose of the composition for treatment of neurodegenerative diseases may be from about 0.01 mg / kg of body weight to about 50 mg / kg of body weight of the patient in need of treatment. A dose of the composition for treatment of metabolic diseases may be from about 1 mg / 70 kg of body weight to about 100 mg / 70 kg of body weight of the patient in need of treatment, and a maximum dose per day is about 200 mg / 70 kg of body weight of the patient in need of treatment.

The invention relates to a method for measuring available phosphorus in planting soil. The method is characterized by comprising the steps of (1) drawing a working curve; (2) weighing a soil sample of 0.5000g-1.0000g, putting the soil sample into a 150ml conical flask, adding NH4F and HCl extracting agents into the conical flask, shaking up the mixture, standing still for 1.5h at room temperature, carrying out dry filtration by non-phosphorus filter paper, and using a 100mL dry beaker to contain filtrate to be measured, wherein 40-45mL c(NH4F) is equal to 0.015mol / L, and c(HCl) is equal to 0.3mol / L; (3) moving 10.0mL of filtrate to be measured into a 25mL colorimetric tube, adding 2-5 drops of dinitrophenol indicator, HCl and NH3.H2O to adjust the test solution to be slight yellow, then adding 1.5mL-2mL of an antimony-molybdenum anti-mixing color developing agent into the test solution, diluting the test solution to the scale by distilled water, shaking up, developing in water bath at the temperature of 40-45 DEG C for 20min-30min, or standing still at the room temperature of 25 DEG C for 40min, cooling, measuring the light absorption value at a part with the wave length of 700nm on a spectrophotometer, and calculating the content of the available phosphorus in the sample by a regression equation of a working curve, wherein c(HCl) is equal to 0.5mol / L, and c(NH3.H2O) is equal to 0.5mol / L. The method is high in analysis speed, good in selectivity, high in sensitivity, low in analysis cost and suitable for popularization.