The invention discloses a treatment method and a separation and recovery system of money printing wastewater and belongs to the technical field of the environment-friendly equipment. The treatment method of the money printing wastewater comprises the following steps: pressurizing the money printing wastewater to be treated to the range of 2-3MPa, and then carrying out coarse filtration to remove large-particle substances and obtain a filtrate; performing membrane filtration and separation on the filtrate, thereby obtaining a filtered concentrated liquid and a filtered clear liquid, respectively; performing reverse osmosis treatment on the filtered clear liquid, and removing the salts of the wastewater, thereby obtaining a reverse osmosis concentrated liquid and a reverse osmosis clear liquid; regulating the pH value of the reverse osmosis clear liquid until the reverse osmosis clear liquid is neutral, performing biochemical treatment on the reverse osmosis clear liquid and discharging the treated liquid after the liquid is up to standard; performing evaporating treatment on the reverse osmosis concentrated liquid and the filtered concentrated liquid, and separating to obtain a concentrated liquid and water, and performing de-solidification treatment on the concentrated liquid and conveying the water to mix with the original money printing wastewater for continuous treatment. The method is simple and reliable in operation and high in separation efficiency, and therefore, innocent and reduced emission of the money printing wastewater is reduced; the system is simple in structure, easy to operate, convenient to maintain, safe and reliable in operation, and good in treatment effect.