The invention discloses a GC-
Orbitrap-MS screening and analyzing method for
pesticide residues in animal-derived food. The method comprises the following steps: (1) extraction: homogenizing an animal-derived
food sample, mixing the homogenized animal-derived
food sample with an extraction
solvent and an extraction salt, carrying out oscillation extraction to obtain an extraction solution, and taking a supernatant I; (2) purification: mixing the supernatant I obtained in the step (1) with a purifying agent for purification, collecting a supernatant II, and filtering to obtain a to-be-detected liquid sample; (3)
chromatography-
mass spectrometry detection: separating
pesticide residues in the to-be-detected sample solution by adopting
gas chromatography, and then detecting by adopting
Orbitrap-MS with an EI
ion source so as to obtain the content of the
pesticide residues in the animal-derived food. The method disclosed by the invention has the characteristics of high
recovery rate, good precision, strong applicability, small organic
reagent dosage and the like; various technical indexes can meet the requirements of daily detection and analysis of various animal-derived foods, and important
technical support is provided for the field of
food safety.