The invention discloses a high-efficiency
alcohol effect dispelling and liver protecting composition, and a preparation method and an application thereof. The composition comprises, by weight, 280-390 parts of dehydrated
Ampelopsis grossedentata leaves, 210-580 parts of
Hovenia acerba Lindl., 140-300 parts bof corn
oligopeptide powder and 90-130 parts of Acai instant
powder, wherein the dehydrated
Ampelopsis grossedentata leaves undergoes ultrasonic extraction, the content of total flavonoids in the obtained extract is not less than 35%, and the content of dihydromyricetins is 25-32%; the
Hovenia acerba Lindl. undergoes
ethanol refluxing extraction, and the content of total flavonoids in the obtained extract is not less than 8%; and the Acai instant
powder is prepared through Acai beating, filtering for residue removal, filtrate concentration, auxiliary material adding, and mixing and
drying. A result of test shows that the composition significantly degrades
ethanol in
rat blood, continuously enhances the activity of ADH in liver of mice, effectively prevents
alcohol-induced liver GSH depletion and MDA increase, reduces the TG content, and has good alcoholic
liver injury prevention and treatment effects.