Traditional Chinese veterinary medicine composition or animal food additive for preventing and/or treating kidney diseases

A technology for animal food and kidney disease, applied in the field of medicine, can solve the problems of high cost of western medicine treatment, inability to repair the kidneys, severe pain for pets, etc., and achieves the effects of broad application prospects, protection of animal kidney function, and easy availability of raw materials.

Pending Publication Date: 2022-05-20
四川嗨葆生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The curative effect of Western medicine is fast and the effect is remarkable, but it only plays the role of rapid detoxification and replaces the function of the kidney, and cannot repair the damaged kidney. Long-term use will gradually lose the function of the still functioning nephron until the disease worsening; and the cost of western medicine treatment is high, and the suffering of pets is great, and it is difficult for ordinary families to afford the high cost of treatment

Method used

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  • Traditional Chinese veterinary medicine composition or animal food additive for preventing and/or treating kidney diseases
  • Traditional Chinese veterinary medicine composition or animal food additive for preventing and/or treating kidney diseases
  • Traditional Chinese veterinary medicine composition or animal food additive for preventing and/or treating kidney diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1, the oral liquid preparation of preparation Chinese veterinary medicine composition

[0028] Recipe: rhubarb, salvia. Wherein, the mass ratio of rhubarb and salvia miltiorrhiza is 3:7.

[0029] Preparation:

[0030] (1) Weigh rhubarb and salvia miltiorrhiza according to the formula, add water and reflux to extract according to the volume ratio of 1:10, extract continuously for 2 times, combine the filtrates and concentrate them into extracts for later use.

[0031] (2) The extract is diluted with distilled water into an oral liquid, wherein 1 g of the oral liquid uses 1 g of raw medicinal materials.

Embodiment 2

[0032] Embodiment 2, the tablet of preparation Chinese veterinary medicine composition

[0033] Recipe: rhubarb, salvia. Wherein, the mass ratio of rhubarb and salvia miltiorrhiza is 3:7.

[0034] Preparation:

[0035] (1) Weigh rhubarb and salvia miltiorrhiza according to the formula, add water and reflux to extract according to the volume ratio of 1:10, extract continuously for 2 times, combine the filtrates and concentrate them into extracts for later use.

[0036] (2) Add appropriate proportion of starch and dextrin in the field of tablets to the extract, granulate and dry, and then compress into 1g tablets, named "Shenhuang Tablets". Among them, 1 piece of "Shenhuang Tablet" uses 5g of raw medicinal materials.

[0037] The beneficial effects of the present invention are demonstrated through experimental examples below.

experiment example 1

[0038] Experimental example 1, research on the protective effect of the Chinese veterinary drug composition of the present invention on experimental acute kidney injury in rats

[0039] 1. Experimental method

[0040] Select 60 healthy rats, half male and half male, divided into 6 groups, 10 in each group, respectively normal group, model group, positive drug group (dexamethasone 1mg / kg), Danshen group, rhubarb group, and "ginseng group". Pornography” group.

[0041] The "Shenhuang Tablets" group was dissolved in distilled water ("Shenhuang Tablets" produced in Example 2) and administered by intragastric administration at 4 g / kg body weight for 7 consecutive days. The Danshen group dissolved the Danshen tablets in distilled water and administered them by intragastric administration at 4 g / kg body weight for 7 consecutive days; For the preparation method, refer to Example 2, the only difference is that the formula is replaced by a single Danshen; for the preparation method of...

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Abstract

The invention discloses a traditional Chinese veterinary medicine composition or an animal food additive for preventing and / or treating kidney diseases, and belongs to the field of medicines. The traditional Chinese veterinary medicine composition is a preparation prepared from the following raw material medicines in parts by weight: 2.8-3.2 parts of rheum officinale and 6.8-7.2 parts of salvia miltiorrhiza. Compared with salvia miltiorrhiza or rheum officinale with the same dosage, the traditional Chinese veterinary medicine composition has an obvious better effect of reducing creatinine and urea nitrogen in rat blood, so that the traditional Chinese veterinary medicine composition consisting of salvia miltiorrhiza and rheum officinale in a specific ratio plays a synergistic role in preventing acute kidney injury and protecting kidney functions. In addition, the traditional Chinese veterinary medicine composition can effectively reduce the levels of blood creatinine and urea nitrogen of cats with chronic renal failure, and can effectively treat chronic renal failure. The traditional Chinese veterinary medicine composition is composed of salvia miltiorrhiza and rheum officinale according to a specific ratio, the medicines are simple and easy to obtain, the preparation process is simple, and the application prospect is wide.

Description

technical field [0001] The invention belongs to the field of medicaments, and in particular relates to a Chinese veterinary medicine composition composed of rhubarb and salvia miltiorrhiza and its application in preparing medicines or animal food additives for preventing and / or treating kidney diseases. Background technique [0002] With the development of social economy, as an option to improve the quality of life, more and more families have kept pets, and dogs and cats are the most common among pets. The number of domestic dogs and cats in my country is increasing, and their health is more and more valued by people. The improvement of the quality of life is also accompanied by the extension of the life span of dogs and cats, and the diseases of dogs and cats are increasing year by year and developing in a variety of ways. At present, senile diseases and chronic diseases of dogs and cats are increasing year by year. Common medical diseases, eye diseases, dental diseases, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61P13/12A23K10/30A23K50/40
CPCA61K36/708A61K36/537A61P13/12A23K10/30A23K50/40A61K2236/331A61K2236/39A61K2300/00
Inventor 张阳杨晓宇辛佳亮唐伯娇李钇霏
Owner 四川嗨葆生物科技有限公司
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