195 results about "Diastole" patented technology

Described are devices and methods for treating degenerative, congestive heart disease and related valvular dysfunction. Percutaneous and minimally invasive surgical tensioning structures offer devices that mitigate changes in the ventricular structure (i.e., remodeling) and deterioration of global left ventricular performance related to tissue damage precipitating from ischemia, acute myocardial infarction (AMI) or other abnormalities. These tensioning structures can be implanted within various major coronary blood-carrying conduit structures (arteries, veins and branching vessels), into or through myocardium, or into engagement with other anatomic structures that impact cardiac output to provide tensile support to the heart muscle wall which resists diastolic filling pressure while simultaneously providing a compressive force to the muscle wall to limit, compensate or provide therapeutic treatment for congestive heart failure and / or to reverse the remodeling that produces an enlarged heart.

Apparatus is provided including first and second chambers, adapted to be in fluid communication with first and second volumes of oxygenated blood of a subject, respectively, the first and second chambers having first and second surfaces, respectively. A third surface is adapted to apply an elastically-derived force, at least a first and second portions of the third surface in mechanical communication with, respectively, the first and second surfaces, during at least a portion of a cardiac cycle. A pressure-sensitive valve is coupled between the first and second chambers, the valve adapted: (a) to be in an open position during at least a portion of systole, such that the first chamber is in fluid communication with the second chamber; and (b) to be in a substantially closed position during diastole, such that the first chamber is substantially not in fluid communication with the second chamber. Other embodiments are also described.

A perfusion system for off-pump coronary artery bypass is provided in order to make the off-pump coronary artery bypass easier and safer and to restrict the amount of bleeding to a degree for not affecting operations by occluding the vessel in concurrency with the perfusion, including a blood removal portion, a pump, and a perfusion portion for returning blood pumped out by the pump in the form of an injection of the blood in pulses in response to a diastolic phase of the heart.

A device used to treat heart disease by decreasing the size of a diseased heart, or to prevent further enlargement of a diseased heart. The device works by limiting the volume of blood entering the heart during each cardiac cycle. The device partitions blood within the heart, and protects the heart from excessive volume and pressure of blood. The device is placed within the interior of the heart, particularly within a ventricular cavity. The device is a hollow sac, with two openings, which simulates the shape and size of the interior lining of a ventricle of a normal heart. It allows the ventricle to fill through one opening juxtaposed to the annulus of the inflow valve to a predetermined, normal volume, and limits filling of the heart beyond that volume. It then allows blood to be easily ejected through the second opening through the outflow valve. By limiting the amount of blood entering the ventricle, the ventricle is not subjected to the harmful effect of excessive volume and pressure of blood during diastole, the period of the cardiac cycle when the heart is at rest. This allows the heart to decrease in size, or to reverse remodel, and to recover lost function. In some applications, a second device may be simultaneously placed inside the heart to take up excessive space between the heart and the primary device.