The present invention provides compounds useful as agents for the prevention or treatment of a
disease associated with abnormal
serum uric acid level which has a uricosuric activity or the like. The present invention relates to 5-membered
heterocyclic derivatives represented by the following general formula (I) having
xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a
disease associated with
abnormality of
serum uric acid level, prodrugs thereof, or salts thereof. In the formula (I), T represents nitro, cyano and the like; ring J represents
aryl or heteroaryl; Q represents carboxy, 5-tetazolyl and the like; Y represents H, OH, NH2,
halogen, haloalkyl and the like; X1 and X2 independently represent CR2 or N; R2 represents H,
alkyl and the like; R1 represents
halogen, cyano, haloalkyl, A-D-E-G-L-M, -N(-D-L-M)2 and the like, in the formula, A represents a
single bond, O, S and the like; D, G and M independently represent optionally substituted alkylene, cycloalkylene, heterocycloalkylene,
arylene, heteroarylene and the like; E and L independently represent a
single bond, O, S, COO, SO2 and the like.