129 results about "Nuciferine" patented technology

The invention disclosed a way to successively extract active ingredients from carpohole of north aweto. The invention adopts super critical CO2 to extract sterin substances, precipitating with alcohol to get nucleoside substances with cordycepin and Cordyceps polyose, separating with normal phase low pressure gel silica chromatography to get crude cordycipin, preparative reversed-phase high-performance liquid chromatography to get cordycepin crystal with high purity. The invention can not only successively extract sterin substances and Cordyceps polyose (CM-1) from the carpohole of north aweto, it can also get the cordycepin metamer; it is not applicable to small experiments but also applicable to industrial production. Since the producers can extract many substances by one treatment of carpohole, the invention can not only decrease the industrial cost but also make the biggest economic returns.

The invention discloses a co-catalytic reaction system for preparing rare ginsenosides. The co-catalytic reaction system comprises glycosyltransferase GT (a); sucrose synthase SUS (b); uridine diphosphate UDP (c); and saccharose (d). Experiments show that in the presence of the saccharose and little UDP, an enzyme combination composed of the glycosyltransferase and the saccharose is capable of replacing an in-vitro reaction system to synthesize UDP sugar, one of expensive materials for the rare ginsenosides, and efficiently and economically converting substrates such as protopanoxadiol or protopanaxatriol into the rare ginsenosides, wherein the UDP is about 1/4 of the UDP sugar in price and is 1% of its original dosage; thus, preparation cost of the rare ginsenosides is greatly saved, and large-scale commercial preparation of the ginsenosides is better facilitated.

The invention provides a method for inspecting quality of indigowoad leaf Chinese medicament, which comprises the following steps: processing indigowoad leaves by sample preprocessing means such as water extraction, ethanol processing, extraction with ethyl acetate and water saturated n-butyl alcohol sequentially, concentration an volume fixation; obtaining a finger-print of the indigowoad leaf Chinese medicament by electron spray mass spectrometry; measuring the nucleoside content and purine content of the indigowoad leaf Chinese medicament by high performance liquid chromatography; and measuring the total flavonoid content of the indigowoad leaf Chinese medicament by UV-VIS spectrophotometry, and integrating the finger-print and the measure data of the content to evaluate the quality of the indigowoad leaf Chinese medicament. The quality inspection method is accurate, quick, convenient and effective.

The present invention provides a lotus-active-ingredient-containing skin cleansing composition and a preparation method thereof, and the composition comprises the following ingredients: hydrogenated olive oil, coconut oil, hydrogenated palm oil, hydrogenated almond oil, avocado tree fruit fat oil, avocado oil, hydrogenated soybean oil, wheat germ oil, a tea extract, sodium hydroxide, allantoin, tea powder, nuciferine, lotus pollen, lotus seed powder, and essence and deionized water. The lotus-active-ingredient-containing skin cleansing composition makes full use of natural active ingredients in the lotus, has good skin cleansing effect, also has the effects of conditioning and maintaining the skin, and is mild and low-stimulation, after use of the skin cleansing composition, the skin is not easy to dry, has good comfortable feeling and is not easy to itch.

The invention provides a method for extracting nuciferine from lotus leaves, which is characterized by comprising the following steps: crushing lotus leaf materials; adding an acidic water solution the amount of which is 8-15 times that of the materials; extracting for 2-3 times while heating; adding the extracting solution into a macroporous resin column and a cation resin column; washing with water until the cation resin is neutral; eluting with 4-7 times of sodium chloride solution to remove active components, thus obtaining an eluent; adding a nanofiltration membrane, and concentrating to obtain a concentrated solution; and regulating the pH value to 8-10, precipitating, crystallizing the precipitate with ethanol for 2-3 times, and drying the obtain the product. The process has the advantages of simple operation, low energy consumption and less pollution in the production process, high product content and no residue of organic solvent, thereby being suitable for industrial popularization.

The invention relates to a self-help betel nut. The betel nut comprises a betel nut semi-finished product prepared according to the traditional betel nut preparation technology and not coated with betel nut brine, and is characterized by also comprising a betel nut brine which is isolated from the betel nut semi-finished product and independently packaged. The invention also provides the betel nut brine, which is prepared by adding a lotus leaf product and/or lotus leaf extract instead of lime into a conventional betel nut semi-finished product. The betel nut semi-finished product and the betel nut brine are respectively packaged, thus the kinds and edible amount of the brine are chosen by the consumer; thus the ' halogenation ' phenomenon does not occur on the betel nut products, therefore the defects of the existing betel nut product and the brine preparation technology are made up. Moreover, nuciferine and lotus leaf flavone have obvious effects on weight reduction, fat reduction, virus resistance, bacteria inhibition, detoxification and oxidation resistance. The prepared betel nut brine not only extends the kinds of betel nut brine, but also increases the special function of the betel nut brine.

The invention relates to a method for preparing nuciferine from lotus leaf; the process takes lotus leaf medical material as raw material and includes the steps that: the lotus leaf medical material is shredded, and is soaked in acid and extracted for 2-3 times, ammonia water is used for adjusting pH, and then the steps of concentration, chloroform dissolving, active carbon column decoloration, alumina column separation and chloroform-ethanol-ammonia water mixed solution elution are conducted to collect nuciferine fractions and recover reagents, and then the end products are obtained after placement crystallization, chloroform and ethanol recrystallization. The process is suitable for scaling up.

The invention relates to a method for ionic liquid extraction/HPLC (high performance liquid chromatography) detection of nuciferine in lotus leaves. The method comprises steps as follows: (1) sample extraction: a lotus leaf powder sample is weighed and put in a container provided with a stirring bar, an ionic liquid solution in the solid-to-liquid ratio being 1: (20-60) is added, and extraction is performed under the microwave assistance at the microwave power being 200-600 w for 2-12 min; (2) detection: HPLC is adopted for detection under the HPLC chromatographic conditions that a Kromasil ODS-C18 column is adopted and has the specifications being 4 mm*250 mm, 5 mu m; a flowing phase is acetonitrile-water-triethylamine-glacial acetic acid; the flowing speed is 0.5-1 ml/min; the detection wavelength is 270 nm; the column temperature is 25 DEG C. The method is simple, convenient, rapid, accurate, high in repeatability and suitable for measuring the content of nuciferine in the lotus leaves.

The invention provides combined application of nuciferine and analogue thereof and a drug. The drug is used for treating or preventing hyperuricemia and reducing the serum uric acid level.

The invention provides a skin-care composition containing lotus active ingredients and a preparation method of the skin-care composition. The skin-care composition comprises the following components: glycerin, 1,3-butanediol, squalene, polydimethylsiloxane, modified polydimethylsiloxane, dicaprylyl carbonate, isopropyl myristate, cetearyl alcohol, white beeswax, titanium dioxide, iron oxides, sodium chloride, nuciferine, lotus pollen, allantoin, sodium hyaluronate, methylparaben, propylparaben, diazolidinyl urea, iron oxide red, iron oxide yellow, essence and deionized water. The skin-care composition is a powder product which takes full advantage of the lotus active ingredients, and the types and consumption of the various components are set reasonably; by adoption of the reasonable preparation method, the color of the prepared skin-care product approximates the human skin color, and the color difference is avoided after the skin-care product is applied to the skin surface; and meanwhile, the skin moisturizing degree is improved obviously, the skin trans-epidermal water loss is reduced, and the skin elasticity is improved.

The invention discloses lotus leaf fruit jelly containing edible glue, a sweet agent and edible flavoring essence. The lotus leaf fruit jelly also contains lotus leaf extract comprising nuciferine and lotus leaf flavone. The lotus leaf fruit jelly comprises the following components by weight percentage: 0.01 to 0.05 weight percent of nuciferine, 0.05 to 0.5 weight percent of lotus leaf flavone, 0.6 to 1.2 weight percent of edible glue, 0.04 to 16 weight percent of sweet agent, 0.07 to 0.10 weight percent of edible flavoring essence, and the balance being water. The nuciferine and the lotus leaf flavone have remarkable functions of weight losing, blood fat reduction, bacteriostasis, antivirus, detoxication and oxidation resistance. Not less than 10g of the lotus leaf fruit jelly for everyday has obvious effects of reducing blood fat, losing weight, promoting the urination and relaxing the bowels, and removing intestine toxin. For long-time taking, the lotus leaf fruit jelly can resist ageing and can not cause impacts like excretion burden due to excessive taking.

The invention concretely relates to a lotus-leaf slimming teabag and a production method thereof, belonging to the technical field of teabag. The method comprises: 1) spreading the fresh lotus leaves for 6 to 8 hours till the leaves are soft and leaf color is changed from fresh green to dark green; cutting into strips of 1 to 2 cm; killing in a continuous roller fixation machine; rolling in a tearolling machine for 20 to 30 minutes, drying in a vacuum dryer for 10 minutes at a temperature of 30 to 60 DEG C under 0.05 to 0.08 MPa; crushing and sieving with an analyzing sieve to obtain the lotus-leaf powder containing 10 % of water, namely, raw material 1; 2) mixing licorice, cassia seed, oriental waterplantain rhizome, green tea, Chrysanthemum morifolium, gynostemma pentaphylla, honeysuckle flower and dried haw pieces, crushing and sieving with an analyzing sieve to obtain raw material 2; and 3) mixing the raw material 1 and the raw material 2, sterilizing by using pasteurization and then packaging to obtain the lotus-leaf slimming teabag. The key points of the invention are that the lotus leaf is pretreated with matte rolling, so that effective components in the lotus leaves are easy to dissolve. Compared with the control, dissolution rates of flavonoids and nuciferine in the lotus leaves are increased by 30-40 % and 35-48 % respectively.

The invention mainly aims to prevent and treat a series of syndromes caused by ketosis of the periparturient cows by using lotus leaves and some antioxidative substances. The powder mainly has an effect of preventing and treating some postpartum diseases easily caused by improper feeding management of postpartum cows and physiological factors of the cows. The powder is mainly prepared from calciumgluconate, potassium gluconate, iodized salt, propylene glycol, vitamin A, vitamin D, vitamin E, vitamin B12, nicotinic acid, carotenoid and nuciferine, and is mainly used for preventing postpartum paralysis of the cows, postpartum hemorrhage, retained placenta, cow ketosis, abomasum displacement, milk down, fatty liver and endometritis. The powder has precise components, is high in safety and easy to manufacture, is prepared from the readily available materials and low in manufacturing cost, can supplement nutrition and trace elements which are required by the postpartum cows in time, and has a good effect on prevention of the postpartum syndrome of the cows. The feeding cost can be greatly reduced, and the powder has relatively high economical benefits.

The invention discloses a lotus leaf cake. The lotus leaf cake comprises the following components of flour, eggs and sucrose and further comprises active ingredient of lotus leaf, wherein, the active ingredients of lotus leaf include nuciferine and flavonoid from lotus leaf, the content of the nuciferine in the lotus leaf cake ranges from 0.003 percent to 0.03 percent by weight, and the content of the flavonoid from lotus leaf ranges from 0.015 percent to 0.5 percent by weight; the nuciferine and the flavonoid from lotus leaf have the functions of obvious weight reduction, fat decreasing, bacteriostasis, antivirus, detoxication, oxidation resistance, and the like; if at least 10 g of the lotus leaf cake is consumed each day, the lotus leaf cake has the effect of obvious fat decreasing, weight reduction, diuresis, catharsis and intestine detoxication, and also has the function of senile-resistance for long-term consumption, and the influence of burden of excretion due to excessive consumption does not exist. The lotus leaf cake has the functions of fat decreasing, weight reduction, diuresis, catharsis, intestine detoxication, and the like.

The invention discloses a diet drink and a preparation method thereof. The diet drink is made from the flowing materials in parts by weight: 8 to 20 of green tea extracts containing 65% to 90% of tea polyphenols, 1 to 2 of lotus leaf extracts containing 3% to 6% of nuciferine, 100 to 300 of bean cake nanoparticles with a particle size distribution range of 70 to 800 nm, and 4 to 7.11 millions of drinking water. The method comprises the steps as follows: dissolving the lotus leaf extracts in ethanol to make a solution A; dissolving the green tea extracts in drinking water to make a solution B; and dissolving the bean cake nanoparticles in drinking water, adding the solution A, mixing for 0.5 to 12 hours, adding the solution B, heating to 80 DEG C and fractionating to remove ethanol, adding the drinking water, and thoroughly mixing; and sterilizing and packaging under sterile conditions. The functional drink contains green tea extracts, lotus leaf extracts and other active components, has a function of inhibiting fat accumulation, and is good in dietary therapy for obesity or overweight people. Since the active components are adsorbed on the bean cake nanoparticles and not liable to be affected by external conditions such as illumination and temperature, the solubility and the stability are greatly improved.

The invention discloses a method for extracting nuciferine in folium nelumbinis by the aid of ultrasonic processes. The method includes steps of 1, smashing and then sieving the folium nelumbinis to obtain folium nelumbinis powder; 2, mixing the folium nelumbinis powder and nanometer silicon dioxide with each other and then grinding the folium nelumbinis powder and the nanometer silicon dioxide to obtain mixtures; 3, mixing the mixtures obtained at the step 2 and extraction solvents with one another; 4, arranging a container with mixtures in an ultrasonic cleaner and extracting the mixtures to obtain extract mixtures; 5, filtering the extract mixtures, then diluting the extract mixtures by the aid of extraction agents, analyzing diluted solution by the aid of liquid chromatography and measuring the content of the nuciferine. The method for extracting the nuciferine in the folium nelumbinis by the aid of the ultrasonic processes has the advantages that the nuciferine is extracted by the aid of the ultrasonic extraction processes and is detected by the aid of the liquid chromatography, and the method is high in detection precision and low in extraction and analysis operation difficulty.

The invention relates to a preparation method of a deacidifying agent with lotus leaves and belongs to the technical field of preparation of the deacidifying agent. For solving the problem that an adsorption deacidifying agent in the prior art has single effect and high limitation, cannot effectively remove oleic acid, and is liable to decompose during adsorption. The preparation method includes the steps of: drying and grinding fresh lotus leaves, extracting nuciferine under ultrasonic wave, grinding and activating dried lotus leaves to prepare a microporous deacidifying agent supporter, and compositing the nuciferine with the microporous deacidifying agent supporter to support the nuciferine onto the activated deacidifying agent supporter to effectively remove oleic acid in plants. The deacidifying agent has low oil loss rate being only 0.1% and is improved in adsorption efficiency by 25-30% than other deacidifying agents, is simple in preparation process, is green and environment-friendly and is free of environment pollution.

The invention discloses a medicine composition for preventing and treating the gout and a preparation method thereof. The medicine composition is prepared by mixing nuciferine, almond, lapis lazuli, liensinine and jujuboside, which are used as active ingredients, the medicine composition can be made into various preparations according to a conventional preparation process, and the curative effect for preventing and treating the gout is remarkable.

The invention discloses a lotus leaf bean curd, comprising the active ingredient of lotus leaf. The active ingredient of the lotus leaf comprises nuciferine and flavone in the lotus leaf. In the lotus leaf bean curd, the nuciferine accounts for 0.002-0.025% and the flavone in the lotus leaf accounts for 0.01-0.15% according to weight contents, wherein, the flavone in the lotus leaf and the nuciferine has the obvious functions of weight losing, fat reducing, bacteriostasis, antivirus, detoxification, anti-oxidation, etc. The lotus leaf bean curd has the obvious effects of reducing fat, losing weight, promoting urine, relaxing bowels and expelling of toxin after being eaten 20-1000g every day; and the lotus leaf bean curd can be against aging after being eaten for a long time and overeat can not cause excretion burden and other influences. Therefore, the invention is the lotus leaf bean curd with the functions of reducing fat, losing weight, promoting urine, relaxing bowels and expelling of toxin.

The present invention relates to a selenium-enriched heart-nourishing tea and a production method thereof. The selenium-enriched heart-nourishing tea is characterized in that the tea comprises the following components by mass percentage: 20-30% of selenium-enriched ampelopsis grossedentata leaves, 10-20% of selenium-enriched ginkgo leaves, 10-20% of lotus leaves, and 30-50% of selenium-enriched green tea. The production method of the selenium-enriched heart-nourishing tea is as follows: preparation of powder of the selenium-enriched ampelopsis grossedentata leaves, the selenium-enriched ginkgo leaves and the lotus leaves: removing impurities from fresh leaves, carrying out steam enzyme deactivation and sterilization on the fresh leaves to remove herbal flavor, baking the leaves at a temperature of 60 DEG C, and crushing and mesh screening the leaves to get raw material powder; preparation of the selenium-enriched green tea: crushing and mesh screening dried green tea to get green tea powder; and uniformly mixing the powder of the selenium-enriched ampelopsis grossedentata leaves, the selenium-enriched ginkgo leaves and the lotus leaves with the selenium-enriched green tea powder according to a ratio to get the heart-nourishing tea. The present invention utilizes the compatibility of bioflavonoids and natural organic selenium to provide complementary functions and multiplied efficacy. Nuciferine has efficacy of clearing heat and reducing blood fat, clearing stasis and detoxifying, timely supplying nutrition for heart and lung, timely eliminating metabolic waste harmful to heart and liver functions, refreshing nerve and qi, and promoting strength and health.

The invention discloses a lotus leaf egg roll. The components of the egg roll comprises flour, eggs, cane sugar, and lotus leaf effective components which comprises nuciferine and lotus leaf flavone; the weight content of the nuciferine in the egg roll is 0.01 to 0.05 percent, and the weight content of the lotus leaf flavone is 0.05 to 0.5 percent; the nuciferine and the lotus leaf flavone have obvious functions of weight reducing, lipid lowering, bacteriostasis, antivirus, detoxification, antioxidation and the like; if at least 10g of the egg roll is eaten as food everyday, obvious effects of lipid lowering, weight reducing, diuresis and catharsis, and intestinal detoxification can be achieved; and long term use is anti-aging, and no influence such as excretion burden can be caused by overuse. Therefore, the egg roll has the functions of lipid lowering and weight reducing, diuresis and catharsis, intestinal detoxification and the like.

The invention discloses a puffed food made by lotus leaves. The finished product with a certain shape and taste can be obtained by the following steps: raw materials are added with water and then stirred into wet blank, then the processes of puffing, cutting and granulating, cooling and transporting, rolling and sheeting, and roasting are carried out on the wet blank, and the flavoring is added into one of the processes. The raw materials comprise grain powder and lotus leaver powder which can pass through a 60-mesh sieve with less than or equal to 10% of water content, wherein, the weight ratio of the grain powder and the lotus leaver powder is 1:0.02-0.1, the water content of the wet blank is 20-25%, the adding amount of the flavoring is 5-10% of the total weight of the raw materials, the water content of the finished product is 3-6%, and the weight content of nuciferine in the finished product is 0.002-0.015%. The puffed food of the invention has the advantages of losing weight, reducing fat, promoting urination, relaxing bowels and expelling toxin and is an ideal snack food with the functions of weight loss and health care.

The invention provides a use of nuciferine in the preparation of inflammatory cancer translation preventing and/or blocking medicines, that is, a use of a compound represented by a formula shown in the specification or pharmaceutically acceptable salts, solvates, polycrystals, enantiomers or a racemic mixture thereof in the preparation of tumor preventing and/or blocking medicines. In vivo experiments show that the above nuciferine compounds can block the inflammatory cancer translation of the digestive tract, have a digestive tract tumor prevention function, and can especially prevent the translation of moderate and severe enteritis to intestine cancer and prevent the intestine cancer. The above compounds are from traditional Chinese medicines, have small toxic side effects, and can be used to prepare medicines for preventing and/or blocking the inflammatory cancer translation of digestive tract organs especially the intestine.