133 results about "Garcinia" patented technology

The invention describes a pharmaceutical composition and method for treating cancer comprised of A) 2,3-dimethoxy-5-methyl-1,4-benzoquinone and / or B) at least one of wild yam root, teasel root, balm of gilead bud, bakuchi seed, dichroa root, kochia seed, kanta kari, bushy knotweed rhizome, arjun, babul chall bark, opopanax and bhumy amalaki; optionally one or more of frankincense, garcinia fruit, vitex, dragons blood, mace, sage and red sandalwood with at least c) one compound capable of maximizing oxidative mitochondrial function preferably riboflavin or vitamin B2 derivatives, FAD, FMN, 5-amino-6-(5′-phosphoribitylamino)uracil, 6,7-Dimethyl-8-(1-D-ribityl)lumazine, ribitol, 5,6-dimethylbenzimidazole, tetrahydrobiopterin, vitamin B1, lipoic acid, biotin, vitamin B6, vitamin B12, folate, niacin, vitamin C and pantothenate and / or d) at least one lactic acid dehydrogenase inhibitor (preferably 2′,3,4′5,7-pentahydroxyflavone) and optionally f) an alkalizing agent (aloe vera, chlorella, wheat grass, sodium or potassium bicarbonate, potassium) g) an antiproliferative herb (speranskia or goldenseal) and h) a pharmaceutically acceptable carrier.

The invention describes a nutraceutical composition and method for preventing / treating cancer comprised of A) quinones (2,3-dimethoxy-5-methyl-1,4-benzoquinone, thymoquinone, tocopherolquinone) B) compounds capable of maximizing oxidative mitochondrial function preferably riboflavin, FAD, FMN, 6,7-Dimethyl-8-(1-D-ribityl)lumazine, ribitol, 5,6-dimethylbenzimidazole, tetrahydrobiopterin, vitamin B1, lipoic acid, biotin, vitamin B6, vitamin B12, folate, B3, C and pantothenate C) lactic acid dehydrogenase inhibitors; 2′,3,4′5,7-pentahydroxyflavone, epigallocatechin gallate, quercetin, citric acid, rosemary, black walnut, clove, nutmeg, licorice root, coriander, cinnamon, ginger root, myrrh gum and green tea D) alkalizing agents: aloe vera, chlorella, wheat grass, apple cider vinegar, burdock root, kudzu root, alfalfa, barley grass, spirulina, parsley leaf, calcium, magnesium, potassium or bicarbonate salts E) potent tumoricidal herbs; gromwell root, wild yam, beth root, teasel root, balm of gilead bud, frankincense, bakuchi seed, dichroa root, kochia seed, kanta kari, sweet myrrh, galbanum, garcinia fruit, mace, white sage and tumoricial plant derived constituents: gambogic acid, shikonin, diosmin or boswellic acid F) an antiproliferative herb (speranskia or goldenseal) and G) a pharmaceutically acceptable carrier.

The invention relates to a formula and production method for preparing a yellow wheat straw dye. The yellow wheat straw dye is mainly prepared from locust tree flower, garcinia, white alum, an iron ion compound solution and mineral water. The production method mainly comprises the following steps: material selection, cutting, drying, immersion, hot boiling, mixing, precipitation and dyeing to obtain the finished product. The yellow wheat straw dye prepared from purely natural plants is purely natural, green and environment-friendly, and has the advantages of no pollution and no toxic or side effect on the human body.

Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.

A method of making an alternative bottled water comprising as main ingredients, D-ribose, L-carnitine, Coenzyme Q10, Adenosine triphosphate, Taurine, Garcinia combgia, Chromium polynicotinate, or chromium picolate with or without L-Aspartic acid to provide cardiovascular fitness and overall physical energy. Said energy fitness water may also contain a non-nutritive or nutritive sweetener, aroma and coloring. The bottled water prepared from these ingredients has pH range from 3.5 to 7.0 dependent on processing and packaging of the bottled water.

(Problems) To provide a highly safe dietetic composition originating in green coffee beans by which excellent dietetic effects can be obtained and which contributes to the prevention and treatment of life style-related diseases such as diabetes.(Means for Solving Problems) A dietetic composition characterized by comprising, as the active ingredient, a polar solvent extract of defatted green coffee beans. It is preferable that the above-described polar solvent extract is an extract obtained by using water-containing ethanol, still preferably water-containing ethanol having an ethanol concentration of from 40 to 90% (wt / wt). It is preferable that the above-described defatted green coffee beans are those obtained by extracting green coffee beans with N-hexane to thereby separate oily components therefrom. It is recommended to combine the above-described dietetic composition with one or more members selected from among salacia extract, evening primrose extract, sesamine and garcinia. This dietetic composition is usable as a material for foods, drinks, drugs, or skin preparations for external use.

In this patent we describe the purification of prenylated benzophenones from the fruit rinds of Garcinia species and its evaluation as an inhibitor for Histone acetyltransferases p300 and PCAF. We have found that prenylated benzophenones are potent HAT inhibitors of p300 (IC50-1 μM) and pCAF (IC50-15 μM). The inhibitors significantly repress the p300 HAT dependent transcriptional activation from in vitro assembled chromatin template but had no effect on transcription from DNA. These results suggest that the compounds could be specific to HATs. Thus these compounds should be useful as biological switching molecule for evaluating the role of p300 and PCAF in cellular functions and may be useful as new chemical entities for the development of anticancer drugs.

The invention relates to the field of plantation of sand-binding plants, in particular to a planting design method for planting a sand-binding plant community. The method is mainly applied to the eastern region of Inner Mongolia and serious desertification areas in the west of Liaoning province and Jilin province in China. In the design of the plant community, a woody plant Caragana microphylla, herbaceos perennial wheatgrass, dester wormwood, garcinia bark and Panicum miliaceum mubarak hassan shami are adopted; and in the design of the sand-binding plant community, the planting of Caragana microphylla is taken as a main framework, and the herbaceos perennial wheatgrass, the dester wormwood, the garcinia bark and the Panicum miliaceum mubarak hassan shami are planted so as to form the sand-binding plant community. By the method, the problems of serious waste of sand-binding plant seeds and the like in the prior art are solved; the better sand-binding effect is achieved by utilizing the reasonable combination of sand-binding plants; a method for planting plant communities is provided for the modern wind protection and sand fixation; and the method can be widely applied to the sand control and plant slope reinforcement work of highways and railways in northern areas in China.

Formulas for producing compositions for the dietary supplement and nutraceutical products, containing virgin olive oil, vitamins, substances as vincamine, vinpocetine or vinburnine, as well as herbal extracts from Vinca Minor and Crioceras longiflorus. The present invention also relates to the oral administration of these compounds, to alleviate mental fatigue or poor cognitive function and anti-ageing prevention.

The invention relates to the field of medicinal chemistry, in particular to a garcinia derivative (I), a preparation method thereof and the application of the derivative in pharmacy. The derivative is a structural analogue of a garcinia natural product such as gambogic acid and has the molecular weight which is lower than that of the gambogic acid, and hetero atoms and hydrophilic groups are introduced or further salified, so that the absorbability of a gastrointestinal tract is improved; and the derivative has an antitumor effect and can be used for preparing antitumor medicaments.

(Problems) To provide a highly safe dietetic composition originating in green coffee beans by which excellent dietetic effects can be obtained and which contributes to the prevention and treatment of life style-related diseases such as diabetes.(Means for Solving Problems) A dietetic composition characterized by comprising, as the active ingredient, a polar solvent extract of defatted green coffee beans. It is preferable that the above-described polar solvent extract is an extract obtained by using water-containing ethanol, still preferably water-containing ethanol having an ethanol concentration of from 40 to 90% (wt / wt). It is preferable that the above-described defatted green coffee beans are those obtained by extracting green coffee beans with N-hexane to thereby separate oily components therefrom. It is recommended to combine the above-described dietetic composition with one or more members selected from among salacia extract, evening primrose extract, sesamine and garcinia. This dietetic composition is usable as a material for foods, drinks, drugs, or skin preparations for external use.

The invention discloses an external ointment for treating herpes zoster, which comprises the following raw materials in proportion by weight: 45 to 55 grams of gamboge, 15 to 25 grams of red orpiment, 8 to 12 grams of camphol, 4 to 6 grams of hydrargyrum, 8 to 12 grams of menthol, and 1,000 grams of vaseline. According to the proportion, the external ointment is prepared by gradually heating the Vaseline to 100 DEG C, lowering the temperature of the Vaseline to 60 DEG C, mixing the powdered red orpiment, the camphol and the menthol into the Vaseline, reducing the temperature of a mixture to 50 DEG C, adding the gamboge and the hydrargyrum into the mixture, grinding the mixture until mercury globules disappear, gradually cooling the temperature of the mixture to 30 DEG C, and bottling the mixture. The ointment can cure the herpes zoster in short time with single treatment, has stable healing efficacy and convenient use, has significant healing effects on patients suffering from xerosis cutis, pruritus and tinea manuum, has cure rate of over 98 percent, and has good healing effects on verruca acuminate, chancroid, syphilis and other venereal diseases.

The invention relates to the field of natural compounds, especially to two novel compounds extracted from the bark of Garcinia oligantha and having a structural formula as described in the specification, or a pharmaceutically acceptable salt, hydrate or prodrug thereof, and a preparation method, a pharmaceutical composition and application thereof. In the formula, R is a methyl group or -CH2CH2CH=C(CH3)2. The compound can be used for preparation of drugs used for preventing and treating a plurality of tumors like prostatic cancers, liver cancers, lung cancers and colorectal cancers.

The invention discloses a hemostatic anti-inflammation nursing agent and a preparation method thereof. The nursing agent is prepared from the following raw medicinal materials in parts by weight: 20-45 parts of creeping bulbophyllum, 18-30 parts of gambir, 3-7 parts of pterocarpus indicus willd, 6-10 parts of silkworm cocoon, 12-28 parts of solanum melongena, 10-16 parts of rhododendron micranthum, 4-8 parts of oblongleaf garcinia seed oil, 3-9 parts of nicandra flower, 6-8 parts of cardiospermum halicacabum, 0.15-0.25 part of emulsifier and 0.03-0.06 part of surfactant. The hemostatic anti-inflammation nursing agent is reasonable in formula, simple and easily available in raw materials and low in cost, is capable of quickly stopping bleeding and carrying out disinfection and anti-inflammation on a wound, integrates disinfection with hemostasis, is convenient to use, and has a certain practical value in the aspect of clinical trauma nursing.

The invention provides weight loss health food containing hyaluronic acid. The food is formed by wrapping a content with a hyalurate shell and comprises the following raw materials by weight: 5-20 parts of L-carnitine, 10-30 parts of garcinia camnogia extract, 5-30 parts of lotus leaf extract, 1-20 parts of tea polyphenol, 0.1-10 parts of vitamin, 1-30 parts of dietary fiber, 0.1-20 parts of dextrin, 0.1-20 parts of chondroitin sulfate, 0.1-20 parts of glucosamine salt, 0.1-20 parts of collagen, 0.1-20 parts of conjugated linoleic acid glyceride and 0.1-30 parts of hyaluronate. The hyaluronateis a combination of a high molecular hyaluronate and a low molecular hyaluronate in the mass ratio of 20:1-1:20. The high molecular hyaluronate has the molecular weight of 1000KDa-3000KDa, and the low molecular hyaluronate has the molecular weight of 1KDa-800KDa. The weight loss health food has the advantages of losing weight, protecting deployable joints and reducing cutis laxa.

Aromatase inhibitors (AIs) are disclosed which are useful in the treatment and prevention of post-menopausal breast cancer. New AIs derived from natural products are disclosed that are evaluated for clinical utility for treating post-menopausal breast cancer and may also act as chemopreventive agents for preventing breast cancer. Several pure compounds demonstrated AI activity using a noncellular, enzyme-based microsomal and a cell-based aromatase assay. Correlations are made between structural classes with levels of aromatase inhibition. The disclosure may be utilized to direct synthetic modification of natural product scaffolds to enhance aromatase inhibition or to standardize botanical dietary supplements for increased aromatase inhibition activity.

The invention relates to an antitumor medicament which is prepared from the following raw materials: (1) gamboges 0.5-1.5 weight parts, (2) flavescent sophora root 5-15 weight parts, or flavescent sophora root essence 0.1-0.3 weight part, sophocarpidine 0.1-0.3 weight part. The invention also discloses the process for preparing the medicament.

Herbal extracts composition suitable for weight management in mammals is disclosed. The composition comprises a mixture of Garcinia extract, Green tea extract, Green coffee extract and Banaba extract. The method of reducing weight, and treating diabetes in mammals involve oral administration of the composition. The invention further relates to a method of producing and standardizing the individual extract useful for human health.

The invention relates to the technical field of medicine preparation, is a traditional Chinese medicine for preventing and treating chemotherapeutic phlebitis, and solves the problems that the existing medicines for treating the chemotherapeutic phlebitis has a poor effect, high price and the like. A compounded garcinia and radix angelicae ointment for preventing and treating chemotherapeutic phlebitis comprises the following medical components in parts by mass: 500-1000 parts of garcinia, 150-250 parts of radix angelicae, 1000-1500 parts of fritillary, 200-300 parts of rheum officinale, 200-300 parts of camphor, 200-300 parts of borneol, 100-300 parts of costus root and 100-300 parts of mint. According to the invention, the garcinia as a monarch drug is taken as a medicine prescription for treating the chemotherapeutic phlebitis, the treating methods of clearing heat and expelling damp, detoxicating and removing pus, relieving swelling and pain, activating blood and removing blood stasis and dredging main and collateral channels are used to prevent and treat the chemotherapeutic phlebitis.

The invention relates to a pure traditional Chinese medicine lotion for treating gynecological diseases, which comprises the following ingredients in parts by weight: 3-5 parts of argy wormwood leaf, 3-5 parts of garcinia bark, 1-3 parts of belvedere fruit, 1-3 parts of cotex dictamni, 5-8 parts of Mongolian dandelion herb and 5-8 parts of wild chrysanthemum. A medicament is prepared according to the conventional process of medicinal lotion preparations. The pure traditional Chinese medicine lotion has special formula and takes common local Chinese herbal medicines as raw materials, and the cost is low. The pure traditional Chinese medicine lotion has the functions of clearing heat-toxin, killing vermin and reliving itch and good treatment effect. The pure traditional Chinese medicine lotion is characterized by easy production, low cost and good treatment effect. The pure traditional Chinese medicine lotion can be used for treatment and prevention of vaginitis, cervical erosion, vaginal itching, redness and swelling and other gynecological diseases.

Herbal extracts composition suitable for weight management in mammals is disclosed. The composition comprises a mixture of Garcinia extract, Green tea extract, Green coffee extract and Banaba extract. The method of reducing weight, and treating diabetes in mammals involve oral administration of the composition. The invention further relates to a method of producing and standardizing the individual extract useful for human health.

The invention aims at providing a method of efficiently extracting and separating gambogic acid and neogambogic acid from gamboge, serving as a traditional Chinese medicine. The method comprises the following steps: crushing the gamboge, carrying out microwave extraction, and concentrating to obtain an extract A; leaching with petroleum ether, dissolving and filtering with ethanol, and carrying out chromatographic separation by virtue of a simulated moving bed to obtain a component B rich in the gambogic acid and a component C containing the gambogic acid and the neogambogic acid; and recovering a solvent, drying to obtain products, including the gambogic acid with the purity to be above 95 percent and a mixture of 10-20 percent of the gambogic acid and 30-50 percent of the neogambogic acid, in two specifications. The method of extracting the effective components of the gamboge, serving as the traditional Chinese medicine, is simple in step and high in product purity and is capable of simultaneously obtaining the products, including the gambogic acid and the neogambogic acid, in two specifications, fully extracting and separating the effective components from the raw materials and improving the production efficiency while saving the raw material resources.

The invention discloses a kind of macrolide antibiotic and the manufacturing method, the method includes following steps: (1) culture yeasting: óƒ the producing of incubation media: blends glucose, soluble starch, peptone, corn pulp, K2HPO4, MgSO4.H2O, NaCl and water, carries on sterilization; ó yeasts: the garcinia grey chain mycete strain into the sterilized incubation media, shakes the bottle and carries on yeasting; (2) processes the yeasted liquid: óƒ centrifugates yeasted liquid; ó isochoric extract acetic ester, partial acetic ester is inversely extracted by water and the pigment impurities are eliminated; ó� reclaims acetic ester and gets brown oil which has active part; óœ carries on silica pole chromatography and gets the coarse product; ó¦ purifies the coarse product.

The invention discloses a micrococcus luteus strain and an application thereof. The micrococcus strain is morphologically characterized in that the appearance of the bacterial colony of the strain on an LB culture medium is golden yellow, in a concave and cone-frustum shape, opaque, even in edge, smooth and moist in surface, and shiny, and the size of the bacterial colony is approximately 2 millimeters. The strain is gram-positive tetracoccus. The micrococcus luteus strain is a strain which can efficiently decompose high-sulfur coal gangue and release phosphorus.

The invention belongs to the field of traditional Chinese medicines and discloses an oral traditional Chinese medicine for treating erysipelas. The traditional Chinese medicine consists of isatis root, cudweed herb, Chinese rose, amur corktree bark, Chinese atractylode rhizome, wild chrysanthemum, indigowoad leaf, Philippine violet herb, Sinkjang arnebia root, tree peony bark, cape jasmine fruit,twotooth achyranthes root, common ducksmeat herb, India madder root, scandent schefflera stem and leaf and gamboge serving as active ingredients according to certain parts by weight. The oral traditional Chinese medicine has the advantages of simplicity for preparation, good absorbing effect, remarkable curative effect, no side effect, high safety and contribution to relieving symptoms of diseases for patients.

The process for preparation of hypoglycemic foods and formulations thereof, useful as snacks, wholesome or supplementary foods, especially to the Type II diabetics, and a hypoglycemic foods and formulations product of composition with concentration of toasted cereals is ranging between 50-60%, concentration of toasted legumes is ranging between 6-12%, concentration of soy is ranging between 7-15%, concentration of fenugreek is ranging between 2-6%, concentration of spice mix is ranging between 3-7%, concentration of amla fruit pulp is ranging between 0.5-2%, concentration of Garcinia combogia rinds is ranging between 1.5 to 3%, concentration of dry skimmed milk is ranging between 3-6%, concentration of edible oil is ranging between 2-6%, and concentration of vitamin and mineral premix is ranging between 1-3%.

The invention discloses a bedsore paste. The traditional Chinese medicine composition is composed of the following components in parts by weight: lithospermum, ginseng, dog oil, caulis spatholobi, lily, sida acuta, psammosilene tunicoides, garcinia hamburgy hook, willow root, gastrodia elata, polygonum cuspidatum, vitamin C, vitamin B2, radix angelicae, radix achyranthis bidentatae, zaocys dhumnade, lycopodium clavatum, oldenlandia diffusa, houttuynia cordata, chitosan, frankincense, gallnut, radix sophorae flavescentis, raw rheum officinale, patrinia, pseudo-ginseng, garden burnet, angelica sinensis, root of oriental buckthorn, moutan bark and metronidazole. The bedsore paste disclosed by the invention has the functions of clearing away heat and toxic materials, invigorating blood circulation and removing stasis, removing the necrotic tissue and promoting granulation, and dredging channels and collaterals. The bedsore paste disclosed by the invention further has the functions of astringing and relieving pain, invigorating blood circulation and removing stasis and avoiding percolate and infection, and is capable of rapidly controlling infection, remarkable in curative effect in clinical application, unique in curative effect, good in medicine property exertion, low in dosage, convenient to use, simple in production process, convenient to store and suitable for clinical popularization and application.

The invention discloses a medicament for treating periodontitis, which is prepared from the following main raw materials in parts by weight: 9-16 parts of rhizoma alismatis, 7-14 parts of acanthopanax, 10-15 parts of hairy holly leaf, 8-16 parts of commelina diffusa, 6-13 parts of Chinese pear-leaved crabapple, 9-14 parts of populus alba leaf, 8-13 parts of orchis, 6-12 parts of rose hip, 7-13 parts of oblongleaf garcinia seed oil, 9-12 parts of spinach beet, 10-16 parts of dodder, 7-15 parts of Chinese usnea, 3-6 parts of daphne giraldii, 10-14 parts of dandelion and 8-12 parts of sheareria nana. The medicament disclosed by the invention has the effects of clearing away heat and purging pathogenic fire, resisting bacteria and diminishing inflammation as well as eliminating swelling and healing sores, is capable of quickly reducing an inflammatory surface and alleviating pain, has a good effect on treating periodontitis, and is free of toxic or side effect.