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253 results about "L-Aspartate" patented technology

L-Aspartic acid is industrially manufactured by an enzymatic process in which aspartase (l-aspartate ammonia lyase, EC 4.3.1.1) catalyzes the addition of ammonia to fumaric acid. Advantages of the enzymatic production method are higher product concentration and productivity and the formation of fewer byproducts.

Organic-inorganic composite water-absorbing material based on polyaspartic acid and nano montmorillonite and preparation method thereof

The invention relates to an organic-inorganic composite water-absorbing material based on polyaspartic acid and nano montmorillonite and a preparation method thereof. The preparation method of the composite material can be carried out by two modes such as an in-situ polymerization method and physical blending and modification. In the in-situ polymerization method, a product is prepared by carrying out in-situ polymerization on montmorillonite and L-aspartic acid of polyaspartic acid monomer, and comprises the following components in parts by weight: 100 parts of L-aspartic acid and 2-10 parts of nano montmorillonite. In the blending and modification of the polyaspartic acid / nano montmorillonite, the improvement on the mechanical performance of polyaspartic acid resin is realized by the modification action of the montmorillonite on the polyaspartic acid, and the obtained product comprises the following components in parts by weight: 100 parts of polyaspartic acid and 2-15 parts of nano montmorillonite. The high-performance polyaspartic acid / nano montmorillonite composite material provided by the invention has the advantages of convenience in preparation, excellent water-absorbing performance, high water-absorbing rate, strong repeated water-absorbing capability, good salt resistance and high impact resistance and the like, and can be used for the fields of high-molecular water-absorbing materials and sand fixing agents and the like.
Owner:NANJING TECH UNIV

Energy fitness water

A method of making an alternative bottled water comprising as main ingredients, D-ribose, L-carnitine, Coenzyme Q10, Adenosine triphosphate, Taurine, Garcinia combgia, Chromium polynicotinate, or chromium picolate with or without L-Aspartic acid to provide cardiovascular fitness and overall physical energy. Said energy fitness water may also contain a non-nutritive or nutritive sweetener, aroma and coloring. The bottled water prepared from these ingredients has pH range from 3.5 to 7.0 dependent on processing and packaging of the bottled water.
Owner:CHOUDHRY MUHAMMAD S

Construction, expression and application of genetic engineering bacteria for high-production of beta-alanine

InactiveCN103898033AImprove synthesis abilityIndustrial Application AdvantagesBacteriaFermentationBiotechnologyL-Aspartate
The invention provides new genetic engineering bacteria used for producing beta-alanine, having strong synthetic ability and having higher enzyme activity, construction, expression and purification of the high-production engineering bacteria, and methods for synthesis of beta-alanine respectively through whole cell transformation and fermentation liquid direct transformation. A synthetic method comprises the steps: an L-aspartic-alpha-alanine decarboxylase (PanD) gene of lactobacillus plantarum is obtained by a gene engineering method and has the gene sequence number of NC-004567.2, the gene is constructed into a high-efficiency expression vector, then the high-efficiency expression vector is transformed into recipient bacteria, and thus the genetic engineering bacteria for producing beta-alanine are obtained. The genetic engineering bacteria are subjected to fermentation culture, 80 g/L of a substrate can be transformed by whole cells, and the beta-alanine content reaches 59.7 g/L; and the substrate is directly added into a fermentation liquid, the transformation concentration can reach 10 g/L, the beta-alanine content reaches 6.8 g/L, and the synthetic ability is higher than that of conventional reported genetic engineering bacteria.
Owner:TIANJIN INST OF IND BIOTECH CHINESE ACADEMY OF SCI

Complex enzyme preparation for sewage treatment and application method thereof

The invention relates to a complex enzyme preparation for sewage treatment. The complex enzyme preparation is compounded by mixing complex enzyme and mineral water, wherein the weight ratio of the complex enzyme to the mineral water is 1:9-50; and the complex enzyme contains the following components in volume content: 50 to 80 mg / L of bromelain, 50 to 80 mg / L of papain, 15 to 30 mg / L of L-aspartase, 15 to 30 mg / L of glutathione, 100 to 150 mg / L of yeast extract and 50 to 80 mg / L of cellulose. The complex enzyme preparation improves the treatment capability of a sewage plant, reduces the running cost, basically achieves zero release of residual organic sludge, prevents environmental secondary pollution of the sewage treatment, improves the self-purification capability of yielding water of the sewage plant, prevents secondary pollution of the yielding water, prevents secondary eutrophication of the yielding water, and radically solves the problem of environmental protection in operation of the sewage treatment plant.
Owner:麦广鸿 +2

Method for preparing magnesium L-aspartate

The invention provides a method for preparing magnesium L-aspartate. The method comprises the steps as follows: using any one of magnesium carbonate, magnesium oxide and magnesium hydrate, and L-asparaginic acid as raw materials; carrying out reaction with water served as the solvent and with the temperature of 70-80 DEG C; calibrating the pH (Potential of Hydrogen) of reacting liquid to reach 6.0 to 7.5 after the reaction; discoloring and filtering the reacting liquid, and concentrating until supersaturation reaches; cooling supersaturation liquid; and carrying out the methods of freeze drying and vacuum drying to directly prepare the supersaturation liquid into the finished product of magnesium L-aspartate. With the adoption of the technical scheme provided by the invention, organic solvent is not used, and therefore, the safety coefficient of production environment can be improved; the demands of the customers on the residual solvent are increased, and the nonuse of the solvent represents the general trend; and meanwhile, the nonuse of the organic solvent can greatly reduce the cost of raw material, and the cost can be reduced by about RMB5000/ton; and furthermore, the input for the equipment and field in the scheme is low, and the input on the equipment can be reduced by about 20% and the water in the product can be controlled well.
Owner:宜兴市前成生物有限公司

Method for catalytic synthesis of polyaspartic acid by using imidazole type ionic liquid

The invention discloses a method for catalytic synthesis of polyaspartic acid by using imidazole type ionic liquid, relates to a method for synthesizing the polyaspartic acid, and solves the technical problems of low yield, difficult product separation process and high reaction temperature existing in the conventional method for synthesizing the polyaspartic acid by using chloroaluminate type ionic liquid as a reaction solvent. The method comprises the following steps of: adding the imidazole type ionic liquid and L-aspartic acid into a container; heating to 145-158 DEG C and preserving the heat for 0.5-6 hours to obtain mixed liquid of polysuccinimide and the ionic liquid; cooling the mixed liquid and then adding deionized water to separate the polysuccinimide out; washing the polysuccinimide and then dissolving the polysuccinimide by using a sodium hydroxide aqueous solution; adjusting pH value to be 3.0-3.5 by using hydrochloric acid; precipitating with ethanol to obtain polyaspartic acid precipitate; and filtering and drying to obtain the polyaspartic acid. The yield of the polyaspartic acid is 50-70 percent. The method can be used for synthesizing the polyaspartic acid serving as a water treatment scale inhibitor.
Owner:HEILONGJIANG UNIV

Treatment composition containing amlodipine series salt and pril medicament

The invention relates to an amlodipine series salt, which particularly comprises nicotinate, camsilate, pyroglutamate, L-aspartate, maleate and mesylate. The invention also relates to a pril compoundor a pharmaceutical composition of a medicinal salt of the pril compound and a preparation method thereof, and a drug combination medicine box containing a composition of the amlodipine series salt and a composition of sartan compounds. The composition of the invention comprises the following components: a) a certain amount of an amlodipine salt; b) a certain amount of the pril compound or a medicinal salt of the pril compound; and c) a medicinal carrier or a diluting agent. The composition or the medicine box can be used for treating the patients suffering from hypertension, angina pectoris,atherosclerosis, and / or hypersphyxia and treating the patients (including the human beings) having heart danger symptoms.
Owner:BEIJING ROCK PHARMA

Method for constructing engineering bacterium capable of producing beta-alanine and method for producing beta-alanine by adopting engineering bacterium

InactiveCN107338258AIncrease vitalityMeet the needs of industrial scale productionBacteriaFermentationEscherichia coliL-Aspartate
The invention discloses a method for constructing an engineering bacterium capable of producing beta-alanine and a method for producing beta-alanine by adopting the engineering bacterium, belonging to the field of biotechnologies. The invention provides L-aspartate alpha-decarboxylase gene of a bacillus tequilensis strain, as shown in SEQ ID NO.1, and the engineering bacterium comprising the PanD gene. The invention further provides a constructing method of the engineering bacterium capable of producing the L-aspartate alpha-decarboxylase, L-aspartate alpha-decarboxylase obtained through expression and secretion is adopted for transforming L-aspartic acid, and thus beta-alanine is produced. According to the invention, L-aspartate alpha-decarboxylase derived from bacillus tequilensis is adopted for transforming L-aspartic acid for producing beta-alanine for the first time at home and abroad, after the enzyme is expressed in escherichia coli, the generated L-aspartate alpha-decarboxylase has high enzyme activity, the thallus does not need to be crushed and can be directly used for carrying out transformation, L-aspartic acid of 180g/L can be transformed to the maximum, the yield of beta-alanine can achieve 119.8g/L, and the industrial application has the advantages.
Owner:LUDONG UNIVERSITY
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